AU2015374240B2 - Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production - Google Patents

Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production Download PDF

Info

Publication number
AU2015374240B2
AU2015374240B2 AU2015374240A AU2015374240A AU2015374240B2 AU 2015374240 B2 AU2015374240 B2 AU 2015374240B2 AU 2015374240 A AU2015374240 A AU 2015374240A AU 2015374240 A AU2015374240 A AU 2015374240A AU 2015374240 B2 AU2015374240 B2 AU 2015374240B2
Authority
AU
Australia
Prior art keywords
pulp
wnt
dentin
wnt3a
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2015374240A
Other languages
English (en)
Other versions
AU2015374240A1 (en
Inventor
Jill Helms
Daniel J. Hunter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leland Stanford Junior University
Original Assignee
Leland Stanford Junior University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of AU2015374240A1 publication Critical patent/AU2015374240A1/en
Application granted granted Critical
Publication of AU2015374240B2 publication Critical patent/AU2015374240B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/50—Preparations specially adapted for dental root treatment
    • A61K6/58—Preparations specially adapted for dental root treatment specially adapted for dental implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/60—Preparations for dentistry comprising organic or organo-metallic additives
    • A61K6/69—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
AU2015374240A 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production Ceased AU2015374240B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462097502P 2014-12-29 2014-12-29
US62/097,502 2014-12-29
PCT/US2015/067683 WO2016109433A1 (en) 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production

Publications (2)

Publication Number Publication Date
AU2015374240A1 AU2015374240A1 (en) 2017-08-10
AU2015374240B2 true AU2015374240B2 (en) 2021-11-11

Family

ID=56284970

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2015374240A Ceased AU2015374240B2 (en) 2014-12-29 2015-12-28 Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production

Country Status (6)

Country Link
US (2) US10512668B2 (enExample)
EP (1) EP3240562B1 (enExample)
JP (1) JP6887948B2 (enExample)
AU (1) AU2015374240B2 (enExample)
CA (1) CA3009983A1 (enExample)
WO (1) WO2016109433A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201617820D0 (en) * 2016-10-21 2016-12-07 King S College London Dental treatment
CN114469863B (zh) * 2021-11-26 2023-09-26 南方医科大学南方医院 甾醇脂质体作为牙髓和牙本质药物传递系统的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120231091A1 (en) * 2009-11-17 2012-09-13 National University Corporation Okayama University Method for Inducing Differentiation of Dental Pulp Cells Into Odontoblasts
WO2014153548A1 (en) * 2013-03-21 2014-09-25 The Trustees Of Columbia University In The City Of New York Compositions and methods for dental tissue regeneration
US20140371151A1 (en) * 2010-09-09 2014-12-18 The Board Of Trustees Of The Leland Stanford Junior University Use of Liposomal WNT Composition to Enhance Osseointegration

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9554975B2 (en) 2005-03-21 2017-01-31 Glaxo Group Limited Alkyl sulfate free and orthophosphate free dentifrice composition comprising fluoride source and a silica dental abrasive
JP2010520286A (ja) 2007-03-05 2010-06-10 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ Ｗｎｔ組成物およびその使用方法
US20110171607A1 (en) 2007-10-25 2011-07-14 The Trustees Of Columbia University In The City Of New York Biopulp
TWI457141B (zh) * 2008-02-08 2014-10-21 Colgate Palmolive Co 雙組分口腔保健產品
US10391038B2 (en) * 2008-02-08 2019-08-27 Colgate-Palmolive Company Tooth sealant
WO2011063371A1 (en) 2009-11-23 2011-05-26 University Of Medicine And Dentistry Of New Jersey Dentinal drug delivery composition
EP2533764A4 (en) * 2010-02-08 2016-08-31 Univ Nebraska BIOMINERAL AND METAL BINDING LIPOSOME, THEIR SYNTHESIS AND METHOD FOR THE PRODUCTION THEREOF
WO2012122081A2 (en) 2011-03-04 2012-09-13 President And Fellows Of Harvard College Dental treatment systems and uses thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120231091A1 (en) * 2009-11-17 2012-09-13 National University Corporation Okayama University Method for Inducing Differentiation of Dental Pulp Cells Into Odontoblasts
US20140371151A1 (en) * 2010-09-09 2014-12-18 The Board Of Trustees Of The Leland Stanford Junior University Use of Liposomal WNT Composition to Enhance Osseointegration
WO2014153548A1 (en) * 2013-03-21 2014-09-25 The Trustees Of Columbia University In The City Of New York Compositions and methods for dental tissue regeneration

Also Published As

Publication number Publication date
US11260103B2 (en) 2022-03-01
US10512668B2 (en) 2019-12-24
AU2015374240A1 (en) 2017-08-10
JP2018502094A (ja) 2018-01-25
EP3240562A1 (en) 2017-11-08
JP6887948B2 (ja) 2021-06-16
CA3009983A1 (en) 2016-07-07
US20200046801A1 (en) 2020-02-13
WO2016109433A1 (en) 2016-07-07
US20180000893A1 (en) 2018-01-04
EP3240562B1 (en) 2023-03-22
EP3240562A4 (en) 2018-08-15

Similar Documents

Publication Publication Date Title
KR102344321B1 (ko) 알츠하이머 질환 치료시 PI4KIIIα 단백질 및 관련 막 단백질 컴플렉스의 적용
EP2851084B1 (en) Modulation of the Vps10p-domain receptors for the treatment of cardiovascular disease
JP6921755B2 (ja) 脳腫瘍幹細胞の成長、遊走および浸潤性を低下させ脳腫瘍患者の生存率を改善する方法および組成物
US20080226707A1 (en) WNT compositions and methods of use thereof
JP6565121B2 (ja) 代謝障害を治療する方法
US9125862B2 (en) Methods for the treatment of Prader-Willi-like syndrome or non-organic failure to thrive (NOFITT) feeding disorder using an agonist of the oxytocin receptor
KR20210117271A (ko) 근막 손상 예방 및 치료를 위한 아넥신의 사용근각 손상 예방 및 치료를 위한 아넥신의 사용
US20170318057A1 (en) Modulation of the VPS10P-Domain Receptors for the Treatment of Cardiovascular Disease
Du et al. Isoflurane promotes phagocytosis of apoptotic neutrophils through AMPK-mediated ADAM17/Mer signaling
US7696160B2 (en) Compositions useful for and methods of modulating angiogenesis
JP2021505611A (ja) 免疫疾患の予防または治療のためのｒｉｐｋ１阻害剤とｉｋｋ阻害剤の組み合わせ
US20070135340A1 (en) IGF-1 novel peptides
US11260103B2 (en) Compositions and methods for delivering lypophilic agents to dental pulp and for enhancing dentin production
EP3496737B1 (en) Apom-fc fusion proteins, complexes thereof with sphingosine 1-phosphate (s1p), and methods for treating vascular and non-vascular diseases
Jiang et al. Adseverin plays a role in osteoclast differentiation and periodontal disease‐mediated bone loss
KR102488987B1 (ko) 알츠하이머 질환을 치료하는데 사용되는 약물 및 치료 표적제를 스크리닝하는 방법
JP2011522864A (ja) 糖尿病患者における血管リモデリングおよび心血管疾患治療のための治療薬としての非アシル化グレリンおよび類似体
WO2012034070A1 (en) Use of liposomal wnt compositions to enhance osseointegration
KR20040008177A (ko) 신경 사 단백질 세그먼트를 사용하여 세포 사멸을억제하는 방법
US11547685B2 (en) Using probenecid to treat polycystic kidney disease
Bhatia The Role of Secreted Hsp90α in Tissue Repair and Cancer
HK1208802B (en) Modulation of the vps10p-domain receptors for the treatment of cardiovascular disease

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired