JP6827636B2 - 補助装置付き手動注射装置と方法 - Google Patents
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Description
[0001]本出願は、2013年11月13日に出願された米国仮出願第61/903884号の利益を主張し、その全内容が本明細書に参照により援用される。
[0002]本明細書に記載されるのは、ユーザが必要に応じて注射速度を選択的に上昇又は低下させること、及び注射を中断又は停止することを可能にする動力補助装置付き注射器である。
ここでUは印加される遠位方向への力であり、Sは圧縮ばねからバイターに掛かる力であり、μはシリンジスリーブとバイターの間の摩擦係数であり、e、g、d、t、及びGは図24Aに概略的に示される距離を表す。バイターとシリンジスリーブの間に三つの接点を有するモデルでは、バイターを閉構成から開構成へと移動させるためにバイターの第2の側に印加される遠位方向への力の量も同様に、下記のように数学的に説明される。
ここでθは、図24Bに概略的に示される接点の角度を表す。言うまでもなく、これら等式は高度に簡略化されたモデルを説明するもので、本明細書に記載されるバイター608を閉構成から開構成へ移動させるために必要な実際の力を表していない場合があることを理解されたい。
Claims (22)
- 薬剤を注射するための装置であって、
シリンジキャビティを含むシリンジ、前記シリンジキャビティ内に摺動可能に受容されるプランジャー要素、及び前記シリンジキャビティと流体連通する中空針を備え、前記プランジャー要素は近位位置から遠位位置へ移動するように構成されており、
前記装置は更に、前記プランジャー要素に力を伝達するように構成された動力アセンブリ、及び
前記近位位置と前記遠位位置の間の少なくとも一つの中間位置において前記プランジャー要素の移動に可逆的に抵抗するように構成されたユーザ作動式制動アセンブリ
を備え、
前記ユーザ作動式制動アセンブリは、前記プランジャー要素に取り付けられた少なくとも1つの摩擦要素を備え、
前記摩擦要素は、放射方向外側への移動により前記プランジャー要素の移動に抵抗するように構成される、注射装置。 - 前記少なくとも1つの摩擦要素は、前記プランジャーの外表面に取り付けられる、請求項1に記載の装置。
- 前記制動アセンブリは、非作動状態にあるとき前記プランジャー要素の移動に抵抗するように付勢されており、作動状態にあるとき前記プランジャー要素の移動を可能にする、請求項1または2に記載の装置。
- 前記制動アセンブリは、前記プランジャー要素の移動に抵抗するように制動ばねによって付勢されている、請求項2に記載の装置。
- 前記動力アセンブリは機械的ばねを含む、請求項1から4のいずれか一項に記載の装置。
- 前記プランジャー要素は更に、前記プランジャー要素を前記遠位位置に向かって移動させる、ユーザが印加した力を同時に受けるように構成されている、請求項1から5のいずれか一項に記載の装置。
- ハウジングを更に備え、前記シリンジが前記ハウジング内に位置する、請求項1から6のいずれか一項に記載の装置。
- 前記ハウジングは前記プランジャー要素に連結されている、請求項7に記載の装置。
- 前記ハウジングは、ユーザが印加した力を前記プランジャー要素に伝達するように構成されている、請求項8に記載の装置。
- 前記制動アセンブリは柔軟性の細長いブレーキコードを含んでいる、請求項1から9のいずれか一項に記載の装置。
- 前記ブレーキコードは、前記プランジャー要素の移動に可逆的に抵抗する解放可能な摩擦嵌めを提供する、請求項10に記載の装置。
- 前記解放可能な摩擦嵌めは、前記ブレーキコードの解放可能な引張力によって提供される、請求項11に記載の装置。
- 前記制動アセンブリは剛性の摩擦要素を含んでいる、請求項1から9のいずれか一項に記載の装置。
- 前記制動アセンブリは、
(a)前記プランジャー要素の移動に可逆的に抵抗するために、前記シリンジの外表面、または、
(b)前記プランジャー要素の移動に可逆的に抵抗するために、前記シリンジに対して固定された表面に作用する、請求項1から9のいずれか一項又は請求項13に記載の装置。 - 前記制動アセンブリは、中に前記シリンジが位置する開口を含む、請求項1から9のいずれか一項又は請求項13又は請求項14に記載の装置。
- 前記動力アセンブリは、
(a)前記プランジャー要素を前記遠位位置に向かって引っ張るように、
(b)前記プランジャー要素を前記遠位位置に向かって押すように、または
(c)前記プランジャー要素を前記遠位位置に向かって押すように且つ引っ張るように構成されている、請求項1から15のいずれか一項に記載の装置。 - 前記シリンジは、前記ハウジング内に摺動可能に位置し、且つ前記針の遠位先端が前記ハウジング内部に位置する後退位置から、前記針の前記遠位先端が前記ハウジングの遠位側に延びる延長位置に向かって移動するように構成されている、請求項7から9のいずれか一項に記載の装置。
- 延長可能な針シュラウドを更に備え、
(a)前記針シュラウドは、解放可能にロックされた、前記シリンジに対して後退した状態と、前記シリンジに対して延長した位置へ向かう移動が可能なロック解除状態とを有するように構成されている、
(b)前記針シュラウドは、解放可能にロックされた、前記シリンジに対して後退した状態と、前記シリンジに対して延長した位置へ向かう移動が可能なロック解除状態とを有するように構成されており、更に、前記針の前記遠位先端が前記ハウジングの遠位側へ延びる前に前記ロック解除状態に変化するように構成されている、
(c)前記針シュラウドは、前記シリンジに対する後退位置に向かう移動を可能にするロック解除された延長状態と、ロックされた延長状態とを有するように構成されている、又は
(d)前記針シュラウドは、前記シリンジに対する後退位置に向かう移動を可能にするロック解除された延長状態と、ロックされた延長状態とを有するように構成され、前記針シュラウドは、後退状態から延びるとき、ロックされた延長状態に入るように構成されている、請求項1から17のいずれか一項に記載の装置。 - 前記針シュラウドは更に、前記延長状態に到達すると再度ロックされるように構成されている、請求項18に記載の装置。
- シリンジキャビティを含むシリンジ、前記シリンジを収容するハウジング、前記シリンジキャビティに摺動可能に受け入れられるプランジャー、及び前記シリンジキャビティと流体連通する中空針を備え、前記プランジャーが、近位位置から遠位位置へ移動するように構成されている、薬剤を注射するための装置であって、
前記装置は更に、前記プランジャーに力を伝達するように構成された動力アセンブリ、及び前記近位位置と前記遠位位置の間の少なくとも一つの中間位置において前記プランジャーの移動に可逆的に抵抗するように構成されたユーザ作動式の制動アセンブリを備えており、前記装置が、
前記ハウジングに力を印加することであって、この力により前記動力アセンブリが前記プランジャーへ力を伝達し、前記プランジャーを前記遠位位置に向かって移動させ、前記制動アセンブリが非作動状態から作動状態へと移動し、前記制動アセンブリは、前記非作動状態にあるとき前記プランジャー要素の移動に抵抗するように付勢され、前記作動状態にあるとき前記プランジャー要素の移動を可能にすること、及び
前記プランジャーが中間位置にあるとき前記ハウジングに印加される力を減少させることであって、これにより、前記制動アセンブリが、前記動力アセンブリにより前記プランジャーに伝達される力を減少させること
により前記薬剤を注射するように構成されている、装置。 - 前記ハウジングが近位ハウジングと遠位ハウジングとを含み、前記ハウジングに力を印加することが、前記近位ハウジングに遠位方向への力を印加することを含む、請求項20に記載の装置。
- 前記ハウジングに再度力を印加することにより、前記動力アセンブリが前記プランジャーへと力を伝達し、前記プランジャーを前記遠位位置に向かって移動させることを更に含む、請求項20または21に記載の装置。
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EP2421587B1 (en) * | 2009-04-24 | 2019-05-22 | SHL Medical AG | Medicament delivery device |
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JP5645046B2 (ja) * | 2009-09-04 | 2014-12-24 | 株式会社大協精工 | 注射器 |
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JP5786852B2 (ja) * | 2010-03-09 | 2015-09-30 | ニプロ株式会社 | 鼻腔投与容器 |
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GB201015799D0 (en) * | 2010-09-21 | 2010-10-27 | Owen Mumford Ltd | Autoinjectors |
JP5634957B2 (ja) * | 2011-07-29 | 2014-12-03 | 株式会社吉野工業所 | カートリッジ式注射器 |
CN202590081U (zh) * | 2012-05-29 | 2012-12-12 | 宣建民 | 肌肉注射无痛器 |
GB2507541A (en) * | 2012-11-02 | 2014-05-07 | Owen Mumford Ltd | Injector with clutch braking or interruption mechanism |
-
2014
- 2014-11-13 KR KR1020167015148A patent/KR20160086360A/ko not_active Application Discontinuation
- 2014-11-13 US US14/541,095 patent/US10252005B2/en active Active
- 2014-11-13 EP EP14815974.2A patent/EP3068475B1/en active Active
- 2014-11-13 RU RU2016122881A patent/RU2689761C1/ru not_active IP Right Cessation
- 2014-11-13 CA CA2929184A patent/CA2929184A1/en not_active Abandoned
- 2014-11-13 BR BR112016010049A patent/BR112016010049A8/pt not_active Application Discontinuation
- 2014-11-13 WO PCT/US2014/065568 patent/WO2015073740A2/en active Application Filing
- 2014-11-13 CN CN201480061871.2A patent/CN105722539B/zh active Active
- 2014-11-13 MX MX2016006213A patent/MX2016006213A/es unknown
- 2014-11-13 JP JP2016529463A patent/JP6827636B2/ja active Active
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2016
- 2016-12-20 HK HK16114479A patent/HK1226013A1/zh unknown
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Publication number | Publication date |
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CN105722539B (zh) | 2021-01-15 |
CN105722539A (zh) | 2016-06-29 |
RU2016122881A (ru) | 2017-12-19 |
KR20160086360A (ko) | 2016-07-19 |
EP3068475A2 (en) | 2016-09-21 |
WO2015073740A2 (en) | 2015-05-21 |
MX2016006213A (es) | 2016-08-08 |
JP2016537080A (ja) | 2016-12-01 |
BR112016010049A8 (pt) | 2020-04-14 |
US20150165129A1 (en) | 2015-06-18 |
WO2015073740A3 (en) | 2015-08-27 |
CA2929184A1 (en) | 2015-05-21 |
HK1226013A1 (zh) | 2017-09-22 |
US20190262542A1 (en) | 2019-08-29 |
RU2689761C1 (ru) | 2019-05-28 |
US10252005B2 (en) | 2019-04-09 |
EP3068475B1 (en) | 2021-12-15 |
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