JP6820254B2 - 治療用化合物およびその使用 - Google Patents

治療用化合物およびその使用 Download PDF

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Publication number
JP6820254B2
JP6820254B2 JP2017518804A JP2017518804A JP6820254B2 JP 6820254 B2 JP6820254 B2 JP 6820254B2 JP 2017518804 A JP2017518804 A JP 2017518804A JP 2017518804 A JP2017518804 A JP 2017518804A JP 6820254 B2 JP6820254 B2 JP 6820254B2
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membered
alkyl
group
cancer
mmol
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Expired - Fee Related
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Japanese (ja)
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JP2017530176A (ja
JP2017530176A5 (enExample
Inventor
エフ． アントニー ロメロ，
エフ． アントニー ロメロ，
スティーブン アール． マグヌソン，
スティーブン アール． マグヌソン，
リチャード パスター，
リチャード パスター，
ビッキー シャオ−ウェイ ツイ，
ビッキー シャオ−ウェイ ツイ，
ジェレミー マレー，
ジェレミー マレー，
テリー クローフォード，
テリー クローフォード，
ダニエル ジェイ． バーディック，
ダニエル ジェイ． バーディック，
ブライアン ケー． アルブレヒト，
ブライアン ケー． アルブレヒト，
アレクサンドル コート，
アレクサンドル コート，
アレクサンダー エム． テイラー，
アレクサンダー エム． テイラー，
クリストファー ジー． ナスヴェスチャック，
クリストファー ジー． ナスヴェスチャック，
イブ レブラン，
イブ レブラン，
マイケル チャールズ ヒューイット，
マイケル チャールズ ヒューイット，
ヲン ワー ライ，
ヲン ワー ライ，
ケビン チェン，
ケビン チェン，
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Constellation Pharmaceuticals Inc
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Constellation Pharmaceuticals Inc
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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    • C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
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JP2017518804A 2014-10-10 2015-10-10 治療用化合物およびその使用 Expired - Fee Related JP6820254B2 (ja)

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Application Number Priority Date Filing Date Title
CNPCT/CN2014/088315 2014-10-10
CN2014088315 2014-10-10
PCT/CN2015/091614 WO2016055028A1 (en) 2014-10-10 2015-10-10 Therapeutic compounds and uses thereof

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JP2017530176A JP2017530176A (ja) 2017-10-12
JP2017530176A5 JP2017530176A5 (enExample) 2018-11-22
JP6820254B2 true JP6820254B2 (ja) 2021-01-27

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US (1) US10206931B2 (enExample)
EP (1) EP3204360B1 (enExample)
JP (1) JP6820254B2 (enExample)
CN (1) CN107108512B (enExample)
WO (1) WO2016055028A1 (enExample)

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EP3218376B1 (en) * 2014-11-10 2019-12-25 Genentech, Inc. Bromodomain inhibitors and uses thereof
SG10201913587WA (en) 2016-02-05 2020-02-27 Denali Therapeutics Inc Inhibitors of receptor-interacting protein kinase 1
WO2017205536A2 (en) * 2016-05-24 2017-11-30 Genentech, Inc. Therapeutic compounds and uses thereof
AU2017302554A1 (en) 2016-07-25 2019-01-31 Epizyme, Inc. CREBBP related cancer therapy
DK3552017T3 (da) 2016-12-09 2022-05-16 Denali Therapeutics Inc Forbindelser, der er anvendelige som ripk1-inhibitorer
CN110291089B (zh) 2017-01-17 2022-05-27 海帕瑞吉尼克斯股份有限公司 用于促进肝再生或者减少或预防肝细胞死亡的蛋白激酶抑制剂
CN107325092B (zh) * 2017-08-07 2021-01-08 山东鲁宁药业有限公司 一种阿奇沙坦的制备新工艺
CN107643405B (zh) * 2017-09-19 2020-07-17 上海市肺科医院 一种基于自身抗体检测的肺癌诊断试剂盒及其应用
WO2019070742A1 (en) * 2017-10-03 2019-04-11 Sidecar Therapeutics, Inc. APOPTOSIS SIGNAL REGULATION KINASE 1 (ASK 1) INHIBITORS COMPOUNDS
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