JP6789579B2 - 特定の患者集団において神経変性障害を処置する方法 - Google Patents

特定の患者集団において神経変性障害を処置する方法 Download PDF

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Publication number
JP6789579B2
JP6789579B2 JP2018512564A JP2018512564A JP6789579B2 JP 6789579 B2 JP6789579 B2 JP 6789579B2 JP 2018512564 A JP2018512564 A JP 2018512564A JP 2018512564 A JP2018512564 A JP 2018512564A JP 6789579 B2 JP6789579 B2 JP 6789579B2
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apoe4
tramiprosate
composition
score
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JP2018526407A5 (enExample
JP2018526407A (ja
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スーザン アブシャクラ，
スーザン アブシャクラ，
アイダン パワー，
アイダン パワー，
マーティン トラール，
マーティン トラール，
ジョン ヘイ，
ジョン ヘイ，
ジェレミー ユー，
ジェレミー ユー，
ピーター コシス，
ピーター コシス，
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アルジオン， インコーポレイテッド
アルジオン， インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2018512564A 2015-09-10 2016-09-09 特定の患者集団において神経変性障害を処置する方法 Active JP6789579B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201562216404P 2015-09-10 2015-09-10
US62/216,404 2015-09-10
US201662290287P 2016-02-02 2016-02-02
US62/290,287 2016-02-02
US201662302027P 2016-03-01 2016-03-01
US62/302,027 2016-03-01
US201662365809P 2016-07-22 2016-07-22
US62/365,809 2016-07-22
PCT/US2016/051091 WO2017044840A1 (en) 2015-09-10 2016-09-09 Methods of treating neurodegenerative disorders in a particular patient population

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2020161995A Division JP7128536B2 (ja) 2015-09-10 2020-09-28 特定の患者集団において神経変性障害を処置する方法

Publications (3)

Publication Number Publication Date
JP2018526407A JP2018526407A (ja) 2018-09-13
JP2018526407A5 JP2018526407A5 (enExample) 2019-10-24
JP6789579B2 true JP6789579B2 (ja) 2020-11-25

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JP2018512564A Active JP6789579B2 (ja) 2015-09-10 2016-09-09 特定の患者集団において神経変性障害を処置する方法
JP2020161995A Active JP7128536B2 (ja) 2015-09-10 2020-09-28 特定の患者集団において神経変性障害を処置する方法
JP2022128786A Pending JP2022145949A (ja) 2015-09-10 2022-08-12 特定の患者集団において神経変性障害を処置する方法
JP2025023627A Pending JP2025065545A (ja) 2015-09-10 2025-02-17 特定の患者集団において神経変性障害を処置する方法

Family Applications After (3)

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JP2020161995A Active JP7128536B2 (ja) 2015-09-10 2020-09-28 特定の患者集団において神経変性障害を処置する方法
JP2022128786A Pending JP2022145949A (ja) 2015-09-10 2022-08-12 特定の患者集団において神経変性障害を処置する方法
JP2025023627A Pending JP2025065545A (ja) 2015-09-10 2025-02-17 特定の患者集団において神経変性障害を処置する方法

Country Status (21)

Country Link
US (3) US11191742B2 (enExample)
EP (2) EP4275750A3 (enExample)
JP (4) JP6789579B2 (enExample)
KR (2) KR102412997B1 (enExample)
CN (3) CN108289870A (enExample)
AU (1) AU2016319107B2 (enExample)
CA (1) CA2997376C (enExample)
DK (1) DK3347002T3 (enExample)
ES (1) ES2952727T3 (enExample)
FI (1) FI3347002T3 (enExample)
HR (1) HRP20230809T1 (enExample)
HU (1) HUE062511T2 (enExample)
LT (1) LT3347002T (enExample)
MD (1) MD3347002T2 (enExample)
MX (2) MX392677B (enExample)
PL (1) PL3347002T3 (enExample)
PT (1) PT3347002T (enExample)
RS (1) RS64481B1 (enExample)
SI (1) SI3347002T1 (enExample)
SM (1) SMT202300250T1 (enExample)
WO (1) WO2017044840A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2015230972B2 (en) 2014-03-21 2021-05-27 Alzheon, Inc. Methods for treating neurological disorders
WO2017044840A1 (en) * 2015-09-10 2017-03-16 Alzheon, Inc. Methods of treating neurodegenerative disorders in a particular patient population
CN114805211B (zh) 2017-03-21 2024-08-23 润佳（苏州）医药科技有限公司 同位素富集3-氨基-1-丙磺酸衍生物、药物组合物及其用途
CN110003058B (zh) 2018-01-04 2022-01-25 润佳（苏州）医药科技有限公司 3-((l-缬氨酰基)氨基)-3,3-二氘-1-丙磺酸晶型、制备方法及用途
PL3829568T3 (pl) * 2018-08-01 2024-03-25 Alzheon, Inc. Pochodne kwasu sulfopropanowego do leczenia zaburzeń neurodegeneracyjnych
LT3829563T (lt) * 2018-08-01 2025-02-25 Alzheon, Inc. 3-sulfopropano rūgštis neurodegeneracinėms ligoms gydyti
CN111170901A (zh) * 2018-11-13 2020-05-19 润佳（苏州）医药科技有限公司 3-((l-缬氨酰基)氨基)-1-丙磺酸晶型、制备方法及其用途
CN114269949A (zh) 2019-06-17 2022-04-01 阿尔泽恩股份有限公司 用于治疗神经变性病症的方法
CN112791078B (zh) 2019-11-13 2022-12-06 润佳（苏州）医药科技有限公司 同位素富集的3-氨基-1-丙磺酸及其衍生物的用途
MX2024007070A (es) * 2021-12-09 2024-08-22 Alzheon Inc Alz-801 para uso en el tratamiento de la enfermedad de alzheimer.
US20250127734A1 (en) * 2022-02-07 2025-04-24 Alzheon, Inc. Alz-801 for use in treating a covid-19 associated neurological symptom

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5698155A (en) 1991-05-31 1997-12-16 Gs Technologies, Inc. Method for the manufacture of pharmaceutical cellulose capsules
WO1994009155A1 (en) 1992-10-13 1994-04-28 Duke University Methods of detecting alzheimer's disease
US20050031651A1 (en) 2002-12-24 2005-02-10 Francine Gervais Therapeutic formulations for the treatment of beta-amyloid related diseases
US20070010573A1 (en) 2003-06-23 2007-01-11 Xianqi Kong Methods and compositions for treating amyloid-related diseases
US20050142191A1 (en) 2003-06-23 2005-06-30 Neurochem (International) Limited Pharmaceutical formulations of amyloid inhibiting compounds
US20060079578A1 (en) 2003-06-23 2006-04-13 Julie Laurin Pharmaceutical formulations of amyloid inhibiting compounds
WO2005060393A2 (en) 2003-08-11 2005-07-07 California Institute Of Technology Microfluidic large scale integration
JP2008535907A (ja) * 2005-04-12 2008-09-04 ニユーロケム（インターナショナル）、リミテッド アミロイド阻害化合物の薬学的製剤
EP2862581B1 (en) 2006-10-12 2021-08-11 BHI Limited Partnership Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
US20100183513A1 (en) 2006-11-24 2010-07-22 Wolfgang Froestl N-(methyl) -1h-pyrazol-3-amine, n-(methyl)-pyridin-2-amine and n-(methyl)-thiazol-2-amine derivatives for the treatment of diseases associated with amyloid or amyloid-like proteins, like e.g. alzheimer's
JO3076B1 (ar) 2007-10-17 2017-03-15 Janssen Alzheimer Immunotherap نظم العلاج المناعي المعتمد على حالة apoe
EP2322163A1 (en) * 2009-11-03 2011-05-18 Pharnext New therapeutics approaches for treating alzheimer disease
US20120009125A1 (en) 2010-07-06 2012-01-12 Lombard Jay L Apoe4 and apoj biomarker-based prevention and treatment of dementia
DK2605655T3 (en) * 2010-08-19 2019-02-04 Buck Institute For Age Res METHODS OF TREATING SMALL COGNITIVE DISABILITY (MCI) AND RELATED DISORDERS
WO2013168174A1 (en) * 2012-05-08 2013-11-14 Ramot At Tel-Aviv University Ltd. Apoe4 antibodies for treatment of neurodegenerative conditions
JP6424210B2 (ja) * 2013-05-06 2018-11-14 バクスアルタ インコーポレイテッド プールされた免疫グロブリンｇを用いたアルツハイマー病の亜集団の治療
BR112016018170A2 (pt) 2014-02-08 2018-02-20 Genentech, Inc. métodos para tratar doença de alzheimer
AU2015230972B2 (en) 2014-03-21 2021-05-27 Alzheon, Inc. Methods for treating neurological disorders
WO2017044840A1 (en) * 2015-09-10 2017-03-16 Alzheon, Inc. Methods of treating neurodegenerative disorders in a particular patient population

Also Published As

Publication number Publication date
WO2017044840A1 (en) 2017-03-16
SMT202300250T1 (it) 2023-09-06
MD3347002T2 (ro) 2023-10-31
HK1257874A1 (en) 2019-11-01
CA2997376C (en) 2024-05-14
MX2018003023A (es) 2018-06-06
KR20180051561A (ko) 2018-05-16
DK3347002T3 (da) 2023-08-14
US20230414541A1 (en) 2023-12-28
PL3347002T3 (pl) 2023-11-13
RS64481B1 (sr) 2023-09-29
FI3347002T3 (fi) 2023-08-10
US11191742B2 (en) 2021-12-07
CN108289870A (zh) 2018-07-17
JP2022145949A (ja) 2022-10-04
LT3347002T (lt) 2023-09-11
US20220096406A1 (en) 2022-03-31
CN116712422A (zh) 2023-09-08
MX2022003128A (es) 2022-08-02
EP3347002B1 (en) 2023-06-07
JP2025065545A (ja) 2025-04-17
AU2016319107A1 (en) 2018-03-22
KR102412997B1 (ko) 2022-06-23
KR20220042480A (ko) 2022-04-05
AU2016319107B2 (en) 2021-02-25
KR102547164B1 (ko) 2023-06-22
EP4275750A3 (en) 2024-01-17
JP2018526407A (ja) 2018-09-13
CA2997376A1 (en) 2017-03-16
HRP20230809T1 (hr) 2023-10-27
HUE062511T2 (hu) 2023-11-28
EP3347002A4 (en) 2019-04-24
PT3347002T (pt) 2023-07-27
JP2020200352A (ja) 2020-12-17
EP4275750A2 (en) 2023-11-15
SI3347002T1 (sl) 2023-12-29
EP3347002A1 (en) 2018-07-18
CN116712423A (zh) 2023-09-08
MX392677B (es) 2025-03-24
ES2952727T3 (es) 2023-11-03
JP7128536B2 (ja) 2022-08-31

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