JP6782244B2 - 機器を検証するための方法およびシステム - Google Patents

機器を検証するための方法およびシステム Download PDF

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JP6782244B2
JP6782244B2 JP2017541268A JP2017541268A JP6782244B2 JP 6782244 B2 JP6782244 B2 JP 6782244B2 JP 2017541268 A JP2017541268 A JP 2017541268A JP 2017541268 A JP2017541268 A JP 2017541268A JP 6782244 B2 JP6782244 B2 JP 6782244B2
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values
fluorescence
quantities
sample
amount
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JP2018510619A (ja
Inventor
トーマス ウェッセル,
トーマス ウェッセル,
ヨン チュー,
ヨン チュー,
ジェイコブ フロイデンタル,
ジェイコブ フロイデンタル,
デイビッド ウー,
デイビッド ウー,
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ライフ テクノロジーズ コーポレーション
ライフ テクノロジーズ コーポレーション
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/27Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
    • G01N21/274Calibration, base line adjustment, drift correction
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6452Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • GPHYSICS
    • G16INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16BBIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B40/00ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
    • G16B40/10Signal processing, e.g. from mass spectrometry [MS] or from PCR
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Medical Informatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Artificial Intelligence (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Evolutionary Computation (AREA)
  • Software Systems (AREA)
  • Bioethics (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Mathematical Physics (AREA)
  • Signal Processing (AREA)
  • Molecular Biology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
JP2017541268A 2015-02-06 2016-02-05 機器を検証するための方法およびシステム Active JP6782244B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562113077P 2015-02-06 2015-02-06
US62/113,077 2015-02-06
PCT/US2016/016730 WO2016127032A1 (en) 2015-02-06 2016-02-05 Methods and systems for instrument validation

Publications (2)

Publication Number Publication Date
JP2018510619A JP2018510619A (ja) 2018-04-19
JP6782244B2 true JP6782244B2 (ja) 2020-11-11

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JP2017541268A Active JP6782244B2 (ja) 2015-02-06 2016-02-05 機器を検証するための方法およびシステム

Country Status (9)

Country Link
US (1) US10648912B2 (pt)
EP (1) EP3254080B1 (pt)
JP (1) JP6782244B2 (pt)
KR (1) KR102434235B1 (pt)
CN (1) CN107430066B (pt)
BR (1) BR112017016791B1 (pt)
RU (1) RU2017131048A (pt)
SG (1) SG11201706250VA (pt)
WO (1) WO2016127032A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102531008B1 (ko) * 2017-09-28 2023-05-11 주식회사 씨젠 증폭 데이터 표시 방법 및 장치
CN107622185B (zh) * 2017-10-27 2020-08-21 领航基因科技(杭州)有限公司 一种数字pcr浓度计算方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003073233A2 (en) * 2002-02-26 2003-09-04 Pharmacia Corporation Sequence detection system calculator
DE602004031152D1 (de) * 2003-12-06 2011-03-03 Abbott Lab Verfahren und system zum analysieren von reaktione
US7630849B2 (en) * 2005-09-01 2009-12-08 Applied Biosystems, Llc Method of automated calibration and diagnosis of laboratory instruments
US9361426B2 (en) * 2009-11-12 2016-06-07 Esoterix Genetic Laboratories, Llc Copy number analysis of genetic locus
US20110276317A1 (en) * 2010-04-11 2011-11-10 Life Technologies Corporation SYSTEMS AND METHODS FOR MODEL-BASED qPCR
WO2012068276A2 (en) 2010-11-16 2012-05-24 Life Technologies Corporation Systems and methods for the analysis of proximity binding assay data
WO2012106481A1 (en) * 2011-02-01 2012-08-09 Life Technologies Coporation Systems and methods for the analysis of protein melt curve data
KR20120103496A (ko) 2011-03-09 2012-09-19 삼성테크윈 주식회사 실시간 중합효소 연쇄 반응에 있어서 표준 곡선 및 임계값을 획득하는 방법
CN102787121B (zh) * 2012-06-14 2014-04-30 浙江大学 一种转录因子基因功能验证的方法
JP2014029282A (ja) * 2012-07-31 2014-02-13 Shimadzu Corp 分析装置バリデーションシステム及び該システム用プログラム
EP2976434B1 (en) * 2013-03-18 2017-08-02 Life Technologies Corporation Methods and systems for analyzing biological reaction systems
CN103667439B (zh) * 2013-08-02 2015-05-13 福建医科大学附属第一医院 可区分hbv b型和非b型的双探针实时定量pcr法
CN104099370A (zh) * 2014-07-16 2014-10-15 中国人民解放军南京军区福州总医院 肿瘤靶向治疗的非整合慢病毒载体系统及制备方法和应用

Also Published As

Publication number Publication date
EP3254080B1 (en) 2023-10-04
EP3254080A1 (en) 2017-12-13
KR20170134361A (ko) 2017-12-06
SG11201706250VA (en) 2017-08-30
BR112017016791A2 (pt) 2018-04-17
JP2018510619A (ja) 2018-04-19
RU2017131048A (ru) 2019-03-06
US10648912B2 (en) 2020-05-12
CN107430066B (zh) 2021-07-13
US20160231245A1 (en) 2016-08-11
WO2016127032A1 (en) 2016-08-11
BR112017016791B1 (pt) 2023-02-14
CN107430066A (zh) 2017-12-01
KR102434235B1 (ko) 2022-08-22

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