JP6780665B2 - 対物光学系及び光音響イメージング装置 - Google Patents

対物光学系及び光音響イメージング装置 Download PDF

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Publication number
JP6780665B2
JP6780665B2 JP2018025937A JP2018025937A JP6780665B2 JP 6780665 B2 JP6780665 B2 JP 6780665B2 JP 2018025937 A JP2018025937 A JP 2018025937A JP 2018025937 A JP2018025937 A JP 2018025937A JP 6780665 B2 JP6780665 B2 JP 6780665B2
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Prior art keywords
mirror
optical system
sample
objective optical
light
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English (en)
Japanese (ja)
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JP2019002906A (ja
JP2019002906A5 (enExample
Inventor
山宮　広之
広之 山宮
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Yokogawa Electric Corp
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Yokogawa Electric Corp
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Priority to PCT/JP2018/012867 priority Critical patent/WO2018235377A1/ja
Priority to US16/623,135 priority patent/US11435322B2/en
Priority to EP18820212.1A priority patent/EP3644054B1/en
Publication of JP2019002906A publication Critical patent/JP2019002906A/ja
Publication of JP2019002906A5 publication Critical patent/JP2019002906A5/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/22—Details, e.g. general constructional or apparatus details
    • G01N29/24—Probes
    • G01N29/2418—Probes using optoacoustic interaction with the material, e.g. laser radiation, photoacoustics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
    • A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
    • G01N29/02—Analysing fluids
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B17/00—Systems with reflecting surfaces, with or without refracting elements
    • G02B17/02—Catoptric systems, e.g. image erecting and reversing system
    • G02B17/06—Catoptric systems, e.g. image erecting and reversing system using mirrors only, i.e. having only one curved mirror
    • G02B17/0605—Catoptric systems, e.g. image erecting and reversing system using mirrors only, i.e. having only one curved mirror using two curved mirrors
    • G02B17/061—Catoptric systems, e.g. image erecting and reversing system using mirrors only, i.e. having only one curved mirror using two curved mirrors on-axis systems with at least one of the mirrors having a central aperture
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/16—Details of sensor housings or probes; Details of structural supports for sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A61B5/7425—Displaying combinations of multiple images regardless of image source, e.g. displaying a reference anatomical image with a live image

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  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Acoustics & Sound (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
JP2018025937A 2017-06-19 2018-02-16 対物光学系及び光音響イメージング装置 Active JP6780665B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
PCT/JP2018/012867 WO2018235377A1 (ja) 2017-06-19 2018-03-28 対物光学系及び光音響イメージング装置
US16/623,135 US11435322B2 (en) 2017-06-19 2018-03-28 Objective optical system and photoacoustic imaging device
EP18820212.1A EP3644054B1 (en) 2017-06-19 2018-03-28 Objective optical system and photoacoustic imaging apparatus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2017119677 2017-06-19
JP2017119677 2017-06-19

Publications (3)

Publication Number Publication Date
JP2019002906A JP2019002906A (ja) 2019-01-10
JP2019002906A5 JP2019002906A5 (enExample) 2020-01-30
JP6780665B2 true JP6780665B2 (ja) 2020-11-04

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JP2018025937A Active JP6780665B2 (ja) 2017-06-19 2018-02-16 対物光学系及び光音響イメージング装置

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US (1) US11435322B2 (enExample)
EP (1) EP3644054B1 (enExample)
JP (1) JP6780665B2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11596313B2 (en) 2017-10-13 2023-03-07 Arizona Board Of Regents On Behalf Of Arizona State University Photoacoustic targeting with micropipette electrodes
WO2019123958A1 (ja) * 2017-12-18 2019-06-27 横河電機株式会社 対物光学系及び顕微鏡システム
US12161295B2 (en) 2018-03-16 2024-12-10 Arizona Board Of Regents On Behalf Of Arizona State University Deep brain stimulation electrode with photoacoustic and ultrasound imaging capabilities
US11768182B2 (en) * 2019-04-26 2023-09-26 Arizona Board Of Regents On Behalf Of Arizona State University Photoacoustic and optical microscopy combiner and method of generating a photoacoustic image of a sample
US11975327B2 (en) 2019-06-19 2024-05-07 Arizona Board Of Regents On Behalf Of Arizona State University Integrated container adapter for photoacoustic microscopy
KR102316306B1 (ko) * 2020-02-12 2021-10-25 광주과학기술원 실리콘 오일을 이용한 광음향 현미경 시스템
KR102456228B1 (ko) 2020-09-01 2022-10-19 포항공과대학교 산학협력단 투명 초음파 센서 기반 초음파 광학 복합 이미징 시스템
CN112305079B (zh) * 2020-11-02 2022-12-06 之江实验室 一种脉冲光驱动的聚焦式超声发射器
KR20220069176A (ko) 2020-11-19 2022-05-27 삼성전자주식회사 광음향 장치와, 광음향 영상 획득 장치 및 방법
CN112716450A (zh) * 2020-12-23 2021-04-30 广州大学 一种光声内窥成像装置及系统
EP4092406A1 (en) * 2021-05-19 2022-11-23 Hitachi High-Tech Analytical Science Finland Oy An optical assembly for optical emission spectroscopy
JP2023158360A (ja) * 2022-04-18 2023-10-30 株式会社日立ハイテク 分光測定装置
KR102760982B1 (ko) * 2022-11-09 2025-02-05 주식회사 삼영기술 미세 플라스틱 측정 장치

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3184487B2 (ja) * 1990-07-26 2001-07-09 日本分光株式会社 全反射測定装置
JP3136576B2 (ja) * 1992-06-18 2001-02-19 株式会社島津製作所 顕微全反射吸収スペクトル測定装置
US5469744A (en) * 1994-06-16 1995-11-28 Iowa State University Research Foundation Inc. Apparatus for acoustically inspecting a workpiece
US5999836A (en) * 1995-06-06 1999-12-07 Nelson; Robert S. Enhanced high resolution breast imaging device and method utilizing non-ionizing radiation of narrow spectral bandwidth
US8454512B2 (en) 2007-10-25 2013-06-04 Washington University Confocal photoacoustic microscopy with optical lateral resolution
US9528966B2 (en) * 2008-10-23 2016-12-27 Washington University Reflection-mode photoacoustic tomography using a flexibly-supported cantilever beam
US9351705B2 (en) * 2009-01-09 2016-05-31 Washington University Miniaturized photoacoustic imaging apparatus including a rotatable reflector
JP4621781B2 (ja) 2009-03-06 2011-01-26 株式会社東芝 レーザ超音波検査装置
US9864190B2 (en) * 2011-02-24 2018-01-09 The Board Of Trustees Of The Leland Stanford Junior University Confocal microscope, system and method therefor
WO2013078471A1 (en) 2011-11-25 2013-05-30 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Chemical mapping using thermal microscopy at the micro and nano scales
KR101356621B1 (ko) * 2012-04-27 2014-02-04 한국광기술원 광파이버 내장형 트랜스듀서를 이용한 형광과 광음향의 신호검출용 형광-광음향 검출용 소형 광학프로브
WO2016094434A1 (en) * 2014-12-08 2016-06-16 University Of Virginia Patent Foundation Systems and methods for multispectral photoacoustic microscopy
JP6319462B2 (ja) * 2015-01-05 2018-05-09 株式会社島津製作所 Ａｔｒ測定用対物光学系
KR101651154B1 (ko) * 2015-02-04 2016-08-26 포항공과대학교 산학협력단 다심도 영상용 광학 영상장치 및 이를 구비하는 영상 시스템
JP6402677B2 (ja) 2015-04-23 2018-10-10 横河電機株式会社 光音響波検出装置、光音響イメージング装置
CN105548022B (zh) * 2015-12-23 2018-08-10 深圳先进技术研究院 一种暗场照明声学分辨率光声显微镜

Also Published As

Publication number Publication date
US20200173965A1 (en) 2020-06-04
EP3644054A1 (en) 2020-04-29
EP3644054A4 (en) 2020-12-09
US11435322B2 (en) 2022-09-06
EP3644054B1 (en) 2025-06-25
JP2019002906A (ja) 2019-01-10

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