JP6768689B2 - 高アンモニア血症に関連する病気を処置するために操作された細菌 - Google Patents
高アンモニア血症に関連する病気を処置するために操作された細菌 Download PDFInfo
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- JP6768689B2 JP6768689B2 JP2017548375A JP2017548375A JP6768689B2 JP 6768689 B2 JP6768689 B2 JP 6768689B2 JP 2017548375 A JP2017548375 A JP 2017548375A JP 2017548375 A JP2017548375 A JP 2017548375A JP 6768689 B2 JP6768689 B2 JP 6768689B2
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| US10610546B2 (en) | 2015-05-13 | 2020-04-07 | Synlogic Operating Company Inc. | Bacteria engineered to reduce hyperphenylalaninemia |
| BR112017011923A2 (pt) * | 2014-12-05 | 2018-02-27 | Synlogic Inc | bactéria modificada para tratar doenças associadas com hiperamonemia |
| US20160206666A1 (en) | 2014-12-22 | 2016-07-21 | Synlogic, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tighten gut mucosal barrier |
| US11883439B2 (en) | 2015-05-13 | 2024-01-30 | Synlogic Operating Company, Inc. | Bacteria engineered to treat a disease or disorder |
| WO2016210384A2 (en) | 2015-06-25 | 2016-12-29 | Synlogic, Inc. | Bacteria engineered to treat metabolic diseases |
| US11685925B2 (en) | 2015-10-30 | 2023-06-27 | Synlogic Operating Company, Inc. | Bacteria engineered to treat diseases that benefit from reduced gut inflammation and/or tightened gut mucosal barrier |
| US11723932B2 (en) | 2016-01-11 | 2023-08-15 | Synlogic Operating Company, Inc. | Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells |
| WO2017139708A1 (en) | 2016-02-10 | 2017-08-17 | Synlogic, Inc. | Bacteria engineered to treat nonalcoholic steatohepatitis (nash) |
| EP3445857B1 (en) | 2016-04-20 | 2023-07-05 | The Board of Trustees of the Leland Stanford Junior University | Compositions and methods for nucleic acid expression and protein secretion in bacteroides |
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| EP3612198A4 (en) * | 2017-04-17 | 2021-01-13 | The Regents of the University of California | MODIFIED COMMENSAL BACTERIA AND METHODS OF USE |
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| WO2019006246A1 (en) * | 2017-06-30 | 2019-01-03 | The Rockefeller University | N-ACYL AMIDES DERIVED FROM THE HUMAN MICROBIOTE FOR THE TREATMENT OF A HUMAN DISEASE |
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| US12410206B2 (en) | 2018-08-21 | 2025-09-09 | Dsm Nutritional Products, Llc | Oligosaccharide compositions and methods of use thereof for reducing ammonia levels |
| US11980647B2 (en) | 2018-09-05 | 2024-05-14 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases, treating inflammation, and managing symptoms of menopause |
| CA3111795A1 (en) | 2018-09-05 | 2020-03-12 | Solarea Bio, Inc. | Methods and compositions for treating musculoskeletal diseases |
| CN113260635B (zh) | 2018-11-08 | 2023-10-31 | Dsm营养产品有限责任公司 | 寡糖组合物及其使用方法 |
| KR20220003030A (ko) | 2019-04-29 | 2022-01-07 | 신로직 오퍼레이팅 컴퍼니, 인코포레이티드 | 살아 있는 세포 계수 기술에 의한 유전적으로 조작된 미생물의 계수 |
| WO2020237246A1 (en) * | 2019-05-23 | 2020-11-26 | University Of Maryland, Baltimore | Live attenuated non-transmissible vaccines |
| AU2020288624B2 (en) | 2019-06-04 | 2025-09-25 | Cocoon Biotech Inc. | Silk-based products, formulations, and methods of use |
| WO2021107500A1 (ko) | 2019-11-29 | 2021-06-03 | 주식회사 지니스 | 혈중 암모니아 수치 저하능을 갖는 균주 및 이를 포함하는 신경세포 보호용 조성물 |
| CN112924607A (zh) * | 2019-12-05 | 2021-06-08 | 湖北远大生物技术有限公司 | 一种同时检测酶促反应液中α-酮戊二酸和L-谷氨酸的方法 |
| BR112022018571A2 (pt) | 2020-03-20 | 2022-11-01 | Synlogic Operating Co Inc | Microrganismos manipulados para reduzir a hiperfenilalaninemia |
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