JP6758380B2 - 新規ヒドロキシピラノン化合物、この製造方法及びこれを含む化粧料組成物 - Google Patents
新規ヒドロキシピラノン化合物、この製造方法及びこれを含む化粧料組成物 Download PDFInfo
- Publication number
- JP6758380B2 JP6758380B2 JP2018528731A JP2018528731A JP6758380B2 JP 6758380 B2 JP6758380 B2 JP 6758380B2 JP 2018528731 A JP2018528731 A JP 2018528731A JP 2018528731 A JP2018528731 A JP 2018528731A JP 6758380 B2 JP6758380 B2 JP 6758380B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- chemical formula
- hydroxypyranone
- cosmetic composition
- adipocyte differentiation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Description
本発明では、下記化学式1で表される新規なヒドロキシピラノン化合物を示す:
1H NMR(DMSO−d6、δ): 9.22(s、1H)、8.09(s、1H)、6.75(m 、1H)、6.46(s、1H)、5.95(d、1H、J =16.2Hz)、5.50(s、1H)、5.02(s、2H)、2.45(m、2H)、2.00(m、2H)、1.42(m、1H)、1.20( m、2H )、0.88(s 、3H)、0.80(s、3H)
前記実施例で製造した化合物の脂肪細胞分化促進効果を調べるために下記のように行った。
下記表2に記載された組成で通常の方法によって化粧水を製造した。
下記表3に記載された組成で通常の方法によってミルクローションを製造した。
下記表4に記載した組成で通常の方法によって栄養クリームを製造した。
下記表5に記載された組成で通常の方法によってマッサージクリームを製造した。
下記表6に記載した組成で通常の方法によってパックを製造した。
Claims (4)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR20150169644 | 2015-12-01 | ||
KR10-2015-0169644 | 2015-12-01 | ||
KR10-2016-0159460 | 2016-11-28 | ||
KR1020160159460A KR102634263B1 (ko) | 2015-12-01 | 2016-11-28 | 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물 |
PCT/KR2016/013927 WO2017095121A1 (ko) | 2015-12-01 | 2016-11-30 | 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2018536005A JP2018536005A (ja) | 2018-12-06 |
JP6758380B2 true JP6758380B2 (ja) | 2020-09-23 |
Family
ID=59220047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2018528731A Active JP6758380B2 (ja) | 2015-12-01 | 2016-11-30 | 新規ヒドロキシピラノン化合物、この製造方法及びこれを含む化粧料組成物 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10208009B2 (ja) |
EP (1) | EP3385260B1 (ja) |
JP (1) | JP6758380B2 (ja) |
KR (1) | KR102634263B1 (ja) |
CN (1) | CN108495848B (ja) |
TW (1) | TWI715687B (ja) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102076636B1 (ko) * | 2017-08-25 | 2020-02-12 | (주)아모레퍼시픽 | 트리메틸 사이클로헥센 화합물을 유효 성분으로 포함하는 발모 또는 육모 촉진용 조성물 |
KR20190036971A (ko) * | 2017-09-28 | 2019-04-05 | (주)아모레퍼시픽 | 트리메틸 사이클로헥센 화합물을 포함하는 아디포넥틴 생성 촉진용 조성물 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6010005B2 (ja) | 1982-08-20 | 1985-03-14 | 三省製薬株式会社 | 色白化粧料 |
JP2565513B2 (ja) | 1987-09-25 | 1996-12-18 | 三省製薬株式会社 | メラニン生成抑制外用薬剤 |
JP2799193B2 (ja) | 1989-09-14 | 1998-09-17 | 三省製薬株式会社 | 皮膚外用剤 |
JPH07118134A (ja) * | 1992-04-17 | 1995-05-09 | Koichi Shudo | 皮膚外用剤 |
JPH07242527A (ja) * | 1994-03-04 | 1995-09-19 | Shiseido Co Ltd | 皮膚外用剤 |
JP4389101B2 (ja) | 2001-09-04 | 2009-12-24 | 独立行政法人産業技術総合研究所 | コウジ酸エステルおよびその合成方法 |
KR100482668B1 (ko) | 2002-06-22 | 2005-04-13 | 주식회사 태평양 | 히드록시 피라논 유도체 및 이의 제조방법 |
KR100494535B1 (ko) | 2003-02-24 | 2005-06-10 | 주식회사 태평양 | 히드록시 피라논 유도체를 함유하는 피부 미백용 외용제조성물 |
KR100706475B1 (ko) * | 2006-04-07 | 2007-04-10 | (주)아모레퍼시픽 | 신규 히드록시피라논 이합체, 그 염, 이들의 제조방법 및이들을 함유하는 피부 미백용 화장료 조성물 |
US8846723B2 (en) * | 2010-07-29 | 2014-09-30 | Eastman Chemical Company | Esters of O-substituted hydroxy carboxylic acids and preparations thereof |
DE102010054149A1 (de) * | 2010-12-10 | 2012-06-14 | Merck Patent Gmbh | 2-Pyrone |
KR101516582B1 (ko) | 2012-03-23 | 2015-05-11 | 주식회사 엔자임바이오 | 카르니틴 팔미토일트랜스퍼라아제-1의 활성을 촉진시켜 지방세포 내 지방의 분해를 향상시킬 수 있는 청고추 유래 항비만용 조성물 |
KR102175466B1 (ko) * | 2013-11-29 | 2020-11-06 | (주)아모레퍼시픽 | 아이오논(ionone) 유도체 화합물 |
KR102175468B1 (ko) * | 2014-01-20 | 2020-11-06 | (주)아모레퍼시픽 | 히드록시 피라논 유도체 화합물을 포함하는 지방세포 분화 촉진용 화장료 조성물 |
-
2016
- 2016-11-28 KR KR1020160159460A patent/KR102634263B1/ko active IP Right Grant
- 2016-11-30 EP EP16871017.6A patent/EP3385260B1/en active Active
- 2016-11-30 CN CN201680079689.9A patent/CN108495848B/zh active Active
- 2016-11-30 US US15/780,421 patent/US10208009B2/en active Active
- 2016-11-30 JP JP2018528731A patent/JP6758380B2/ja active Active
- 2016-11-30 TW TW105139435A patent/TWI715687B/zh active
Also Published As
Publication number | Publication date |
---|---|
EP3385260A4 (en) | 2018-10-24 |
US20180354925A1 (en) | 2018-12-13 |
EP3385260A1 (en) | 2018-10-10 |
US10208009B2 (en) | 2019-02-19 |
JP2018536005A (ja) | 2018-12-06 |
TW201720805A (zh) | 2017-06-16 |
KR102634263B1 (ko) | 2024-02-06 |
TWI715687B (zh) | 2021-01-11 |
EP3385260B1 (en) | 2020-01-08 |
KR20170064473A (ko) | 2017-06-09 |
CN108495848B (zh) | 2021-08-20 |
CN108495848A (zh) | 2018-09-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6758380B2 (ja) | 新規ヒドロキシピラノン化合物、この製造方法及びこれを含む化粧料組成物 | |
KR100349043B1 (ko) | (폴리)티아알킨산 화합물 및 이의 유도체, 이를 함유하는조성물 및 이의 용도 | |
CN102917685B (zh) | 半胱氨酸衍生物 | |
KR102119465B1 (ko) | 트리메톡시 페닐 화합물 및 그를 포함하는 발모 또는 육모 촉진용 조성물 | |
JP6845243B2 (ja) | 新規ヒドロキシピラノン化合物、この製造方法及びこれを含む化粧料組成物 | |
JP2017502955A (ja) | ヒドロキシピラノン誘導体化合物を含有する脂肪細胞分化促進用の化粧料組成物 | |
CN110121491B (zh) | 3,4,5-三甲氧基肉桂酸酯衍生物、其制备方法以及含有该衍生物的皮肤美白组合物 | |
JP7132326B2 (ja) | トリメトキシフェニル化合物を含む脂肪細胞の分化又はアディポネクチンの生成促進用組成物 | |
TWI729050B (zh) | 水楊酸衍生物、其製備方法和包含其的化妝品組成物 | |
KR102076636B1 (ko) | 트리메틸 사이클로헥센 화합물을 유효 성분으로 포함하는 발모 또는 육모 촉진용 조성물 | |
JP5955867B2 (ja) | ヘテロ環レゾルシノール誘導体、その製造およびその美容用途 | |
KR20190036971A (ko) | 트리메틸 사이클로헥센 화합물을 포함하는 아디포넥틴 생성 촉진용 조성물 | |
KR102202236B1 (ko) | 지방세포 분화 촉진 효능을 갖는 코지산 설파이드 유도체 화합물 및 이를 함유하는 화장료 조성물 | |
WO2017095121A1 (ko) | 신규 히드록시 피라논 화합물, 이의 제조방법 및 이를 포함하는 화장료 조성물 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20190906 |
|
TRDD | Decision of grant or rejection written | ||
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20200813 |
|
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20200825 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20200901 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 6758380 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |