JP6720443B2 - 改善された粘膜輸送を示す医薬用ナノ粒子 - Google Patents

改善された粘膜輸送を示す医薬用ナノ粒子 Download PDF

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JP6720443B2
JP6720443B2 JP2015510490A JP2015510490A JP6720443B2 JP 6720443 B2 JP6720443 B2 JP 6720443B2 JP 2015510490 A JP2015510490 A JP 2015510490A JP 2015510490 A JP2015510490 A JP 2015510490A JP 6720443 B2 JP6720443 B2 JP 6720443B2
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JP2015519331A (ja
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アレクセイ ポポフ
アレクセイ ポポフ
エリザベス エム エンロー
エリザベス エム エンロー
チェン　ホンミン
ホンミン チェン
ジェイムズ ブーラッサ
ジェイムズ ブーラッサ
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カラ ファーマシューティカルズ インコーポレイテッド
カラ ファーマシューティカルズ インコーポレイテッド
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    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
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    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2015510490A 2012-05-03 2013-05-03 改善された粘膜輸送を示す医薬用ナノ粒子 Active JP6720443B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201261642261P 2012-05-03 2012-05-03
US201261642313P 2012-05-03 2012-05-03
US61/642,313 2012-05-03
US61/642,261 2012-05-03
US201261738949P 2012-12-18 2012-12-18
US61/738,949 2012-12-18
US201361784701P 2013-03-14 2013-03-14
US61/784,701 2013-03-14
PCT/US2013/039540 WO2013166436A1 (en) 2012-05-03 2013-05-03 Pharmaceutical nanoparticles showing improved mucosal transport

Related Child Applications (1)

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JP2019182856A Division JP2020015758A (ja) 2012-05-03 2019-10-03 改善された粘膜輸送を示す医薬用ナノ粒子

Publications (2)

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JP2015519331A JP2015519331A (ja) 2015-07-09
JP6720443B2 true JP6720443B2 (ja) 2020-07-08

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JP2015510490A Active JP6720443B2 (ja) 2012-05-03 2013-05-03 改善された粘膜輸送を示す医薬用ナノ粒子
JP2019182856A Pending JP2020015758A (ja) 2012-05-03 2019-10-03 改善された粘膜輸送を示す医薬用ナノ粒子
JP2020193338A Active JP7372897B2 (ja) 2012-05-03 2020-11-20 改善された粘膜輸送を示す医薬用ナノ粒子

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JP2019182856A Pending JP2020015758A (ja) 2012-05-03 2019-10-03 改善された粘膜輸送を示す医薬用ナノ粒子
JP2020193338A Active JP7372897B2 (ja) 2012-05-03 2020-11-20 改善された粘膜輸送を示す医薬用ナノ粒子

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Country Link
US (4) US20130316006A1 (https=)
EP (1) EP2844223A1 (https=)
JP (3) JP6720443B2 (https=)
KR (2) KR102373259B1 (https=)
CN (5) CN111700878A (https=)
AU (3) AU2013256092B2 (https=)
BR (1) BR112014027296B1 (https=)
CA (1) CA2871748C (https=)
CL (3) CL2014002956A1 (https=)
HK (2) HK1208161A1 (https=)
MX (2) MX373352B (https=)
NZ (5) NZ742005A (https=)
WO (1) WO2013166436A1 (https=)

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US10307372B2 (en) 2010-09-10 2019-06-04 The Johns Hopkins University Rapid diffusion of large polymeric nanoparticles in the mammalian brain
WO2012109363A2 (en) 2011-02-08 2012-08-16 The Johns Hopkins University Mucus penetrating gene carriers
CA2863632C (en) 2012-01-19 2017-07-11 The Johns Hopkins University Nanoparticle formulations with enhanced mucosal penetration
US8962577B2 (en) 2012-03-16 2015-02-24 The Johns Hopkins University Controlled release formulations for the delivery of HIF-1 inhibitors
JP6138904B2 (ja) 2012-03-16 2017-05-31 ザ・ジョンズ・ホプキンス・ユニバーシティー 活性剤の送達のための非線状マルチブロックコポリマー薬物コンジュゲート
US9827191B2 (en) 2012-05-03 2017-11-28 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
NZ742005A (en) * 2012-05-03 2019-04-26 Kala Pharmaceuticals Inc Pharmaceutical nanoparticles showing improved mucosal transport
US10864219B2 (en) * 2012-05-03 2020-12-15 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
US11596599B2 (en) 2012-05-03 2023-03-07 The Johns Hopkins University Compositions and methods for ophthalmic and/or other applications
KR102310775B1 (ko) 2012-05-03 2021-10-07 칼라 파마슈티컬스, 인크. 개선된 점막 수송을 나타내는 제약 나노입자
AU2013256064B2 (en) 2012-05-03 2018-01-04 Alcon Inc. Pharmaceutical nanoparticles showing improved mucosal transport
AU2013256008B2 (en) 2012-05-04 2016-02-25 The Johns Hopkins University Lipid-based drug carriers for rapid penetration through mucus linings
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