JP6717741B2 - 画像形成サイトメータ - Google Patents

画像形成サイトメータ Download PDF

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Publication number
JP6717741B2
JP6717741B2 JP2016515661A JP2016515661A JP6717741B2 JP 6717741 B2 JP6717741 B2 JP 6717741B2 JP 2016515661 A JP2016515661 A JP 2016515661A JP 2016515661 A JP2016515661 A JP 2016515661A JP 6717741 B2 JP6717741 B2 JP 6717741B2
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JP
Japan
Prior art keywords
light
sample
image
light source
cytometer
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Japanese (ja)
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JP2016529876A5 (enExample
JP2016529876A (ja
Inventor
マルティン グレンスビェアウ，
マルティン グレンスビェアウ，
ヨハン ホルム，
ヨハン ホルム，
セーレン シェルルッフ，
セーレン シェルルッフ，
ハンセン， フランス アイナー ラヴン
ハンセン， フランス アイナー ラヴン
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Chemometec AS
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Chemometec AS
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/02—Investigating particle size or size distribution
    • G01N15/0205—Investigating particle size or size distribution by optical means
    • G01N15/0227—Investigating particle size or size distribution by optical means using imaging; using holography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429—Signal processing
    • G01N15/1433—Signal processing using image recognition
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T7/00—Image analysis
    • G06T7/0002—Inspection of images, e.g. flaw detection
    • G06T7/0012—Biomedical image inspection
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06V—IMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00—Scenes; Scene-specific elements
    • G06V20/60—Type of objects
    • G06V20/69—Microscopic objects, e.g. biological cells or cellular parts
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/01—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials specially adapted for biological cells, e.g. blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N2015/1006—Investigating individual particles for cytology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/144—Imaging characterised by its optical setup
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1493—Particle size
    • G01N2015/1495—Deformation of particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/061—Sources
    • G01N2201/06113—Coherent sources; lasers
    • G01N2201/0612—Laser diodes
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10056—Microscopic image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/10—Image acquisition modality
    • G06T2207/10064—Fluorescence image
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06T—IMAGE DATA PROCESSING OR GENERATION, IN GENERAL
    • G06T2207/00—Indexing scheme for image analysis or image enhancement
    • G06T2207/30—Subject of image; Context of image processing
    • G06T2207/30004—Biomedical image processing
    • G06T2207/30024—Cell structures in vitro; Tissue sections in vitro

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Theoretical Computer Science (AREA)
  • Quality & Reliability (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Molecular Biology (AREA)
  • Multimedia (AREA)
  • Biomedical Technology (AREA)
  • Signal Processing (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Microscoopes, Condenser (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2016515661A 2013-05-28 2014-05-28 画像形成サイトメータ Active JP6717741B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA201370291 2013-05-28
DKPA201370291 2013-05-28
PCT/DK2014/050151 WO2014191003A1 (en) 2013-05-28 2014-05-28 Image forming cytometer

Publications (3)

Publication Number Publication Date
JP2016529876A JP2016529876A (ja) 2016-09-29
JP2016529876A5 JP2016529876A5 (enExample) 2017-06-29
JP6717741B2 true JP6717741B2 (ja) 2020-07-08

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JP2016515661A Active JP6717741B2 (ja) 2013-05-28 2014-05-28 画像形成サイトメータ

Country Status (9)

Country Link
US (2) US10458896B2 (enExample)
EP (2) EP4027132A1 (enExample)
JP (1) JP6717741B2 (enExample)
KR (1) KR102162213B1 (enExample)
CN (2) CN105579828B (enExample)
AU (1) AU2014273560B2 (enExample)
CA (1) CA2913667A1 (enExample)
DK (1) DK3004838T3 (enExample)
WO (1) WO2014191003A1 (enExample)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20170186262A1 (en) * 2014-02-14 2017-06-29 Rotas Italia SRL Product authentication method
CA2977481C (en) 2015-02-24 2021-02-02 The University Of Tokyo Dynamic high-speed high-sensitivity imaging device and imaging method
CN104990907B (zh) * 2015-07-01 2018-05-08 上海睿钰生物科技有限公司 自动多通道类流式图像荧光分析系统
WO2017036483A1 (en) * 2015-08-28 2017-03-09 Chemometec A/S Continuous image cytometer
EP3372985B1 (en) 2015-10-28 2025-06-25 The University Of Tokyo Analysis device
JP6571210B2 (ja) * 2016-01-27 2019-09-04 株式会社日立ハイテクノロジーズ 観察装置
US11035795B2 (en) 2016-02-18 2021-06-15 Optofluidics, Inc. Methods for identification of particles in a fluid sample
EP3427024A4 (en) * 2016-02-18 2019-11-06 Optofluidics, Inc. SYSTEM AND METHOD FOR CHARACTERIZING PARTICLES IN A LIQUID SAMPLE
DE102016211038A1 (de) * 2016-06-21 2017-12-21 Cytena Gmbh Vorrichtung und Verfahren zum Detektieren von Zellen oder Partikeln in einem Fluidbehälter
SG11201908847TA (en) 2017-03-31 2019-10-30 Life Technologies Corp Apparatuses, systems and methods for imaging flow cytometry
CN107389535A (zh) * 2017-07-18 2017-11-24 深圳小孚医疗科技有限公司 一种显微成像照明系统的照明方法
GB201711886D0 (en) 2017-07-24 2017-09-06 Univ College Cardiff Consultants Ltd Analysing nano - objects
WO2019031048A1 (ja) * 2017-08-08 2019-02-14 ソニー株式会社 情報処理装置、情報処理方法及びプログラム
JP6413006B1 (ja) * 2017-11-28 2018-10-24 リオン株式会社 パーティクルカウンタ
EP3743712B8 (en) * 2018-01-26 2023-07-19 Molecular Devices (Austria) GmbH System and method for intensity stabilization for quantitative fluorescence imaging
MA52114A (fr) 2018-02-28 2021-01-06 Juno Therapeutics Inc Procédés de détection de particules présentes dans une composition cellulaire
WO2019202005A1 (en) 2018-04-17 2019-10-24 Chemometec A/S Depicting of objects
LU100777B1 (de) * 2018-04-23 2019-10-23 Cytena Gmbh Verfahren zum Untersuchen einer Flüssigkeit, die wenigstens eine Zelle und/oder wenigstens ein Partikel enthält
WO2019241443A1 (en) 2018-06-13 2019-12-19 Thinkcyte Inc. Methods and systems for cytometry
US20200158628A1 (en) * 2018-10-22 2020-05-21 Bioelectronica Corporation Multiplexed assay systems and methods
JP2020094925A (ja) * 2018-12-13 2020-06-18 住友電気工業株式会社 品質評価方法
CN109709025B (zh) * 2019-02-12 2021-07-16 军事科学院系统工程研究院卫勤保障技术研究所 一种多模成像光学系统
CN110487686B (zh) * 2019-09-03 2022-09-02 中国工程物理研究院流体物理研究所 一种空气气溶胶单粒子多模态光谱诊断装置及诊断方法
CN110609026B (zh) * 2019-10-31 2020-11-03 福州大学 激光功率反馈控制的上转换荧光成像装置及其成像方法
EP4083603A4 (en) 2019-12-27 2024-04-03 ThinkCyte, Inc. FLOW CYTOMETER PERFORMANCE EVALUATION METHODS AND STANDARD PARTICLE SUSPENSION
EP3851834B1 (en) * 2020-01-16 2024-06-05 Roche Diagnostics GmbH Device for thermocycling biological samples, monitoring instrument comprising the same, and method for thermocycling biological samples using such device
US11806955B2 (en) 2020-02-26 2023-11-07 Depuy Ireland Unlimited Company Method for testing additively manufactured orthopaedic prosthetic components
WO2021200911A1 (ja) 2020-04-01 2021-10-07 シンクサイト株式会社 フローサイトメーター
WO2021200960A1 (ja) 2020-04-01 2021-10-07 シンクサイト株式会社 観察装置
FR3109159B1 (fr) * 2020-04-09 2023-06-23 Interscience Procédé de traitement d’images appliqué aux compteurs de colonies en microbiologie
KR102286722B1 (ko) * 2020-04-14 2021-08-06 주식회사 톱텍 자동 세포 계수 장치 및 그를 이용한 세포 계수 방법
CN111598058A (zh) * 2020-06-24 2020-08-28 无锡市科德科技有限公司 一种基于单一光源的明场和暗场定向反射光源总成
EP4200658A1 (en) * 2020-08-20 2023-06-28 Maytronics Ltd. Multi-region optical filters and systems and methods using same
KR102505687B1 (ko) * 2020-11-30 2023-03-03 디투이모션(주) 혈구계산기를 이용한 반자동 세포 계수 방법
US20240069315A1 (en) * 2021-01-06 2024-02-29 Scopgenx Private Limited A compact portable multimodal microscopy
US20240233089A1 (en) * 2021-07-29 2024-07-11 Shimadzu Corporation Image processing method and image processing apparatus
JPWO2023053679A1 (enExample) * 2021-09-30 2023-04-06
CN114088606B (zh) * 2021-10-23 2023-05-09 广州市艾贝泰生物科技有限公司 细胞分析装置
KR102645654B1 (ko) * 2021-12-22 2024-03-13 (주)얼라인드제네틱스 고효율 다중 스펙트럼 검출을 위한 라인 공초점 세포 계수기
EP4605909A1 (en) * 2022-10-17 2025-08-27 Becton, Dickinson and Company Methods for classifying particles using images based on filtered layers and machine learning models and systems for same
CN116660126A (zh) * 2023-04-06 2023-08-29 北京寻因生物科技有限公司 一种细胞计数仪及其计数方法
JP7393836B1 (ja) * 2023-04-25 2023-12-07 株式会社写真化学 菌体観察装置
WO2025117820A1 (en) * 2023-11-30 2025-06-05 Cellanome, Inc. Objective lens assembly
CN117348225A (zh) * 2023-12-04 2024-01-05 成都丹诺迪医疗科技有限公司 显微装置

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4786165A (en) * 1986-07-10 1988-11-22 Toa Medical Electronics Co., Ltd. Flow cytometry and apparatus therefor
DE3714830A1 (de) * 1987-05-05 1988-11-17 Leitz Ernst Gmbh Kombinierte hellfeld-dunkelfeld- auflichtbeleuchtungseinrichtung
JP3084296B2 (ja) * 1991-02-27 2000-09-04 シスメックス株式会社 フローイメージサイトメータ
US6180415B1 (en) * 1997-02-20 2001-01-30 The Regents Of The University Of California Plasmon resonant particles, methods and apparatus
ATE398185T1 (de) 1997-05-05 2008-07-15 Chemometec As Verfahren und system zur bestimmung von somazellen in milch
US6731100B1 (en) 1997-05-05 2004-05-04 Chemometec A/S Method and a system for determination of somatic cells in milk
US6707555B1 (en) 1998-10-15 2004-03-16 Sysmex Corporation Optical information measuring apparatus
HK1039805A1 (zh) 1998-11-05 2002-05-10 Chemometec A/S 颗粒评价方法以及用於该方法的系统和装置
DE19923822A1 (de) * 1999-05-19 2000-11-23 Zeiss Carl Jena Gmbh Scannende Anordnung, vorzugsweise zur Erfassung von Fluoreszenzlicht
US7738945B2 (en) * 2002-04-19 2010-06-15 University Of Washington Method and apparatus for pseudo-projection formation for optical tomography
GB0227649D0 (en) * 2002-11-27 2003-01-08 Medical Res Council Uses of optical projection tomography methods and apparatus
DE10239548A1 (de) * 2002-08-23 2004-03-04 Leica Microsystems Semiconductor Gmbh Vorrichtung und Verfahren zur Inspektion eines Objekts
DE10239955B3 (de) * 2002-08-26 2004-05-13 Carl Zeiss Smt Ag Mikroskop mit Hell- und Dunkelfeldbeleuchtung
JP4598766B2 (ja) * 2003-04-29 2010-12-15 エス３アイ， エル エル シィ 生物学的微粒子及び非生物学的微粒子を検出し且つ分類するためのマルチスペクトル光学方法及びシステム
DE10361073A1 (de) * 2003-12-22 2005-07-21 Innovatis Ag Verfahren und Vorrichtung zur Aufnahme mikroskopischer Bilder
JP4698992B2 (ja) * 2004-09-14 2011-06-08 浜松ホトニクス株式会社 試料計測装置及び計測方法
US7660045B2 (en) * 2004-11-24 2010-02-09 Takashi Yoshimine Object lens and condenser
JP4982385B2 (ja) * 2005-02-01 2012-07-25 アムニス コーポレイション イメージングフローサイトメータを使用した血液及び細胞の分析
JP2007033381A (ja) * 2005-07-29 2007-02-08 Tokyo Seimitsu Co Ltd 光学式検査装置及びその照明方法
WO2007057016A1 (en) 2005-11-16 2007-05-24 Chemometec A/S Determination of chemical or physical properties of sample or component of a sample
JP4723362B2 (ja) 2005-11-29 2011-07-13 株式会社日立ハイテクノロジーズ 光学式検査装置及びその方法
JP5028014B2 (ja) * 2006-02-08 2012-09-19 株式会社日立ハイテクノロジーズ パターン検査方法及びその装置
JP2008002932A (ja) * 2006-06-22 2008-01-10 Tokyo Seimitsu Co Ltd 試料撮像装置及び試料の照明方法
US7700928B2 (en) * 2007-01-25 2010-04-20 Etaluma, Inc. Apparatus and method for interleaving detection of fluorescence and luminescence
CN101622522A (zh) * 2007-01-26 2010-01-06 贝克顿·迪金森公司 用于细胞计数和分析的方法、系统和组合物
EP2156138A1 (en) 2007-04-18 2010-02-24 ChemoMetec A/S Interferometer actuator
CN101216601B (zh) * 2007-12-29 2010-12-15 中国科学院西安光学精密机械研究所 使用锥镜实现暗场显微及荧光显微的方法及装置
US8143600B2 (en) * 2008-02-18 2012-03-27 Visiongate, Inc. 3D imaging of live cells with ultraviolet radiation
JP2009237486A (ja) * 2008-03-28 2009-10-15 Kawasaki Heavy Ind Ltd ズーム位相差観察装置および位相差観察用照明装置
US20100189338A1 (en) * 2008-04-09 2010-07-29 Nexcelom Bioscience Systems and methods for counting cells and biomolecules
JP2010085194A (ja) * 2008-09-30 2010-04-15 Sysmex Corp 試料分析装置
WO2010045949A2 (en) 2008-10-21 2010-04-29 Chemometec A/S A method and apparatus for analysis of a particle
DE102009004920B4 (de) * 2009-01-16 2018-10-11 Schaeffler Technologies AG & Co. KG Kombiniertes Radial-Axialwälzlager
WO2010088585A1 (en) * 2009-01-30 2010-08-05 Trustees Of Boston University Chemical/biological sensor employing scattered chromatic components in nano-patterned aperiodic surfaces
US20120195024A1 (en) 2009-10-14 2012-08-02 Sharp Kabushiki Kaisha Flexible circuit board connection structure and display device
CN104330346B (zh) 2009-12-04 2017-04-12 生命技术公司 用于声学流式细胞计量术的方法
EP2348301B1 (en) * 2010-01-08 2013-08-21 Sysmex Corporation Sample analyzer
DK2524221T3 (da) * 2010-01-12 2022-05-23 Nexcelom Bioscience Llc Systemer til at tælle celler og biomolekyler
WO2012096153A1 (ja) * 2011-01-12 2012-07-19 株式会社ニコン 顕微鏡システム
US8681215B2 (en) * 2011-04-29 2014-03-25 ProteinSimple Method and particle analyzer for determining a broad particle size distribution
JP6076801B2 (ja) * 2013-03-29 2017-02-08 シスメックス株式会社 血球分析装置および血球分析方法

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Publication number Publication date
WO2014191003A1 (en) 2014-12-04
JP2016529876A (ja) 2016-09-29
KR102162213B1 (ko) 2020-10-07
US20160103058A1 (en) 2016-04-14
CN111220529A (zh) 2020-06-02
EP3004838A1 (en) 2016-04-13
US10458896B2 (en) 2019-10-29
KR20160047432A (ko) 2016-05-02
US10921234B2 (en) 2021-02-16
EP4027132A1 (en) 2022-07-13
EP3004838B1 (en) 2022-03-16
AU2014273560A1 (en) 2015-12-03
US20190323944A1 (en) 2019-10-24
CN105579828B (zh) 2020-02-14
CA2913667A1 (en) 2014-12-04
DK3004838T3 (da) 2022-06-20
CN105579828A (zh) 2016-05-11
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