JP6689743B2 - 抑うつ症状及び不安症状の少なくとも一方を有する患者におけるバソプレッシン受容体１ｂアンタゴニストに対する治療応答を予測する方法 - Google Patents

抑うつ症状及び不安症状の少なくとも一方を有する患者におけるバソプレッシン受容体１ｂアンタゴニストに対する治療応答を予測する方法 Download PDF

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JP6689743B2
JP6689743B2 JP2016520422A JP2016520422A JP6689743B2 JP 6689743 B2 JP6689743 B2 JP 6689743B2 JP 2016520422 A JP2016520422 A JP 2016520422A JP 2016520422 A JP2016520422 A JP 2016520422A JP 6689743 B2 JP6689743 B2 JP 6689743B2
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JP2016521987A (ja
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ホルスボール、フローリアン
ミューラー−マイソック、ベルトラム
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
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    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016520422A 2013-06-17 2014-06-16 抑うつ症状及び不安症状の少なくとも一方を有する患者におけるバソプレッシン受容体１ｂアンタゴニストに対する治療応答を予測する方法 Active JP6689743B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1310782.6 2013-06-17
GBGB1310782.6A GB201310782D0 (en) 2013-06-17 2013-06-17 Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms
PCT/EP2014/062592 WO2014202541A1 (en) 2013-06-17 2014-06-16 Method for predicting a treatment response to a crhr1 antagonist and/or a v1b antagonist in a patient with depressive and/or anxiety symptoms

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JP2016521987A JP2016521987A (ja) 2016-07-28
JP2016521987A5 JP2016521987A5 (enExample) 2017-07-06
JP6689743B2 true JP6689743B2 (ja) 2020-04-28

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US (2) US10190168B2 (enExample)
EP (2) EP3623483A1 (enExample)
JP (1) JP6689743B2 (enExample)
CA (1) CA2914866C (enExample)
DK (1) DK3011048T3 (enExample)
ES (1) ES2759507T3 (enExample)
GB (1) GB201310782D0 (enExample)
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GB201210686D0 (en) 2012-06-15 2012-08-01 Holsboermaschmeyer Neurochemie Gmbh V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level
GB201310782D0 (en) 2013-06-17 2013-07-31 Max Planck Innovation Gmbh Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms
AU2016240213B2 (en) * 2015-04-02 2022-01-27 HMNC Holding GmbH Method of treatment using genetic predictors of a response to treatment with CRHR1 antagonists
AU2016240212B2 (en) * 2015-04-02 2022-01-27 HMNC Holding GmbH Genetic predictors of a response to treatment with CRHR1 antagonists
WO2017035528A1 (en) * 2015-08-27 2017-03-02 Nantneuro, Llc Triazolopyridines and triazolopyrimidines that lower stress-induced p-tau
CN113632174B (zh) 2019-01-23 2025-03-25 密歇根大学董事会 用于nmda、甘氨酸和ampa受体的调节剂的药物基因组学决策支持
WO2022200966A1 (en) * 2021-03-23 2022-09-29 Iluria Ltd. Diagnosis and monitoring medical treatment effectivness for anxiety and depression disorders

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US5591588A (en) 1994-09-20 1997-01-07 Gideon Goldstein Method for the diagnosis of depression based on monitoring blood levels of arginine vasopressin and/or thymopoietin
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FR2796380B3 (fr) 1999-07-15 2001-08-17 Sanofi Synthelabo Nouveaux derives d'aminothiazoles, leur preparation et les compositions pharmaceutiques les contenant
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ATE355102T1 (de) 2001-03-13 2006-03-15 Bristol Myers Squibb Pharma Co 4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6- methoxypyrid-3-yl) pyrazolo- 1,5-aö-1,3,5-triazin,seine enantiomeren und pharmazeutisch annehmbare salze als corticotropin-releasing-factor-rezeptor-ligande
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EP2841068B8 (en) 2012-04-23 2019-03-06 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Crhr1 antagonists for use in the treatment of patients having crh overactivity
GB201210686D0 (en) * 2012-06-15 2012-08-01 Holsboermaschmeyer Neurochemie Gmbh V1B receptor antagonist for use in the treatment of patients having an elevated AVP level and/or an elevated copeptin level
GB201310782D0 (en) 2013-06-17 2013-07-31 Max Planck Innovation Gmbh Method for predicting a treatment response to a CRHR1 antagonist and/or V1B antagonist in a patient with depressive and/or anxiety symptoms

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CA2914866A1 (en) 2014-12-24
JP2016521987A (ja) 2016-07-28
US10190168B2 (en) 2019-01-29
US10837062B2 (en) 2020-11-17
WO2014202541A1 (en) 2014-12-24
EP3011048B1 (en) 2019-08-07
CA2914866C (en) 2024-09-10
US20160153043A1 (en) 2016-06-02
EP3011048A1 (en) 2016-04-27
US20190194752A1 (en) 2019-06-27
ES2759507T3 (es) 2020-05-11
GB201310782D0 (en) 2013-07-31
EP3623483A1 (en) 2020-03-18
DK3011048T3 (da) 2019-11-04

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