JP6678581B2 - ５−フルオロ−１ｈ−ピラゾール類の調製のための方法 - Google Patents
５−フルオロ−１ｈ−ピラゾール類の調製のための方法 Download PDFInfo
- Publication number
- JP6678581B2 JP6678581B2 JP2016534680A JP2016534680A JP6678581B2 JP 6678581 B2 JP6678581 B2 JP 6678581B2 JP 2016534680 A JP2016534680 A JP 2016534680A JP 2016534680 A JP2016534680 A JP 2016534680A JP 6678581 B2 JP6678581 B2 JP 6678581B2
- Authority
- JP
- Japan
- Prior art keywords
- formula
- alkyl
- compound
- cyano
- chlorine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 0 *C(c1c(C(F)(F)F)c(*)n[n]1*)=* Chemical compound *C(c1c(C(F)(F)F)c(*)n[n]1*)=* 0.000 description 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/16—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13194561.0 | 2013-11-27 | ||
| EP13194561 | 2013-11-27 | ||
| PCT/EP2014/075490 WO2015078846A1 (en) | 2013-11-27 | 2014-11-25 | Process for the preparation of 5-fluoro-1h-pyrazoles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016538301A JP2016538301A (ja) | 2016-12-08 |
| JP6678581B2 true JP6678581B2 (ja) | 2020-04-08 |
Family
ID=49674200
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016534680A Active JP6678581B2 (ja) | 2013-11-27 | 2014-11-25 | ５−フルオロ−１ｈ−ピラゾール類の調製のための方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US9725415B2 (https=) |
| EP (1) | EP3083566B1 (https=) |
| JP (1) | JP6678581B2 (https=) |
| KR (1) | KR102367319B1 (https=) |
| CN (1) | CN105934429B (https=) |
| BR (1) | BR112016011890B1 (https=) |
| ES (1) | ES2939161T3 (https=) |
| IL (1) | IL245474B (https=) |
| MX (1) | MX394430B (https=) |
| TW (1) | TWI688557B (https=) |
| WO (1) | WO2015078846A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX360114B (es) * | 2012-07-19 | 2018-10-23 | Bayer Animal Health Gmbh | Procedimiento de preparacion de 5-fluoro-1h-pirazoles. |
| KR102367289B1 (ko) * | 2013-11-27 | 2022-02-23 | 바이엘 애니멀 헬스 게엠베하 | 5-플루오로-1h-피라졸의 제조 방법 |
| EP3590927A1 (en) | 2018-07-05 | 2020-01-08 | Bayer Animal Health GmbH | Novel compounds for controlling arthropods |
| EP3771711A1 (en) | 2019-07-29 | 2021-02-03 | Bayer Animal Health GmbH | Pyrazole derivatives for controlling arthropods |
| UA128873C2 (uk) | 2019-08-14 | 2024-11-13 | Ветокінол Са | Композиції, що містять тиголанер, для боротьби з паразитами |
| DK4157830T3 (da) | 2020-05-27 | 2025-05-26 | Vetoquinol Sa | Fremgangsmåde til fremstilling af 2-chlor-n-(1-cyanocyclopropyl)-5-[2'-methyl-5'-(pentafluorethyl)-4'-(trifluormethyl)-2'h-1,3'-bipyrazol-4-yl]benzamid |
| KR20230028268A (ko) | 2020-05-29 | 2023-02-28 | 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 | 구충성 헤테로시클릭 화합물 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1456419A1 (ru) | 1987-06-18 | 1989-02-07 | Институт элементоорганических соединений им.А.Н.Несмеянова | Способ получени 1-замещенных 3-пентафторэтил-4-трифторметил-5-фторпиразолов |
| JP2817863B2 (ja) * | 1992-02-21 | 1998-10-30 | 宇部興産株式会社 | 含フッ素ピラゾール化合物、その製法及び有害生物防除剤 |
| US5254774A (en) | 1992-12-28 | 1993-10-19 | Minnesota Mining And Manufacturing Company | Preparation of hexafluoropropene oligomers |
| CA2541458C (en) | 2003-10-08 | 2011-09-20 | Eli Lilly And Company | Pyrrole and pyrazole derivatives as potentiators of glutamate receptors |
| HUE026011T2 (en) * | 2006-03-22 | 2016-05-30 | Hoffmann La Roche | Pyrazoles as 11-beta-HSD-1 |
| MX2010007548A (es) | 2008-01-11 | 2010-11-25 | Univ California | Activadores de procaspasas 3, 6 y 7 efectoras. |
| EP2184273A1 (de) | 2008-11-05 | 2010-05-12 | Bayer CropScience AG | Halogen-substituierte Verbindungen als Pestizide |
| BR112013020213A2 (pt) | 2011-02-09 | 2016-08-02 | Syngenta Participations Ag | compostos inseticidas |
| MX360114B (es) * | 2012-07-19 | 2018-10-23 | Bayer Animal Health Gmbh | Procedimiento de preparacion de 5-fluoro-1h-pirazoles. |
| PL2953942T3 (pl) * | 2013-02-06 | 2018-03-30 | Bayer Cropscience Aktiengesellschaft | Podstawione halogenem pochodne pirazolu jako środki do zwalczania szkodników |
-
2014
- 2014-11-25 JP JP2016534680A patent/JP6678581B2/ja active Active
- 2014-11-25 WO PCT/EP2014/075490 patent/WO2015078846A1/en not_active Ceased
- 2014-11-25 TW TW103140710A patent/TWI688557B/zh active
- 2014-11-25 KR KR1020167017080A patent/KR102367319B1/ko active Active
- 2014-11-25 EP EP14805819.1A patent/EP3083566B1/en active Active
- 2014-11-25 US US15/037,564 patent/US9725415B2/en active Active
- 2014-11-25 MX MX2016006976A patent/MX394430B/es unknown
- 2014-11-25 ES ES14805819T patent/ES2939161T3/es active Active
- 2014-11-25 CN CN201480074160.9A patent/CN105934429B/zh active Active
- 2014-11-25 BR BR112016011890-1A patent/BR112016011890B1/pt active IP Right Grant
-
2016
- 2016-05-04 IL IL245474A patent/IL245474B/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| WO2015078846A1 (en) | 2015-06-04 |
| MX394430B (es) | 2025-03-24 |
| IL245474A0 (en) | 2016-06-30 |
| CN105934429B (zh) | 2022-03-04 |
| IL245474B (en) | 2019-12-31 |
| CN105934429A (zh) | 2016-09-07 |
| JP2016538301A (ja) | 2016-12-08 |
| EP3083566A1 (en) | 2016-10-26 |
| ES2939161T3 (es) | 2023-04-19 |
| TW201609662A (zh) | 2016-03-16 |
| BR112016011890B1 (pt) | 2021-11-16 |
| TWI688557B (zh) | 2020-03-21 |
| MX2016006976A (es) | 2016-09-07 |
| US20160289194A1 (en) | 2016-10-06 |
| EP3083566B1 (en) | 2022-12-21 |
| US9725415B2 (en) | 2017-08-08 |
| BR112016011890A2 (https=) | 2017-08-08 |
| KR102367319B1 (ko) | 2022-02-23 |
| KR20160089509A (ko) | 2016-07-27 |
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