JP6673586B2 - 異所性骨化の予防・治療剤及びそのスクリーニング方法 - Google Patents

異所性骨化の予防・治療剤及びそのスクリーニング方法 Download PDF

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JP6673586B2
JP6673586B2 JP2016566426A JP2016566426A JP6673586B2 JP 6673586 B2 JP6673586 B2 JP 6673586B2 JP 2016566426 A JP2016566426 A JP 2016566426A JP 2016566426 A JP2016566426 A JP 2016566426A JP 6673586 B2 JP6673586 B2 JP 6673586B2
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JPWO2016104574A1 (ja
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淳也 戸口田
淳也 戸口田
真 池谷
真 池谷
佳久 松本
佳久 松本
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Kyoto University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/04Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/10Musculoskeletal or connective tissue disorders

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  • Health & Medical Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2016566426A 2014-12-24 2015-12-24 異所性骨化の予防・治療剤及びそのスクリーニング方法 Active JP6673586B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2014261086 2014-12-24
JP2014261086 2014-12-24
PCT/JP2015/085962 WO2016104574A1 (fr) 2014-12-24 2015-12-24 Produits de prévention et/ou de traitement contre l'ossification ectopique et méthode de criblage de ces derniers

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JPWO2016104574A1 JPWO2016104574A1 (ja) 2017-11-09
JP6673586B2 true JP6673586B2 (ja) 2020-03-25

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JP (1) JP6673586B2 (fr)
WO (1) WO2016104574A1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3013623A1 (fr) 2016-02-05 2017-08-10 Memorial Sloan-Ketering Cancer Center Procedes de differenciation de precurseurs de lignees ectodermiques derives de cellules souches
DE102016213684A1 (de) * 2016-07-26 2018-02-01 Tetec Tissue Engineering Technologies Ag Marker und Verfahren zur Beurteilung der Zusammensetzung oder Reinheit einer Zellkultur sowie zur in vitro Bestimmung der Identität einer Knorpelzelle oder einer Synovialzelle
WO2018199142A1 (fr) * 2017-04-27 2018-11-01 国立大学法人京都大学 Procédé de production de cellules de crête neurale et de neurones sympathiques
WO2019051248A1 (fr) * 2017-09-07 2019-03-14 Memorial Sloan-Kettering Cancer Center Procédés de différenciation de précurseurs de lignées ectodermiques dérivés de cellules souches
CA3083253A1 (fr) * 2017-11-30 2019-06-06 Kyoto University Methode de culture de cellules
EP3842525A4 (fr) * 2018-08-22 2022-07-27 Kyoto University Procédé de production d'une cellule précurseur de nerf du tractus intestinal
WO2023106122A1 (fr) * 2021-12-06 2023-06-15 国立大学法人京都大学 Procédé de production de cellules de crête neurale spécialisées pour la différenciation en lignée mésenchymateuse
CN115282261A (zh) * 2022-08-16 2022-11-04 清远市人民医院 血小板衍生生长因子-bb在制备治疗骨关节炎药物中的应用

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JPWO2016104574A1 (ja) 2017-11-09

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