JP6673586B2 - 異所性骨化の予防・治療剤及びそのスクリーニング方法 - Google Patents
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
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- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N2800/10—Musculoskeletal or connective tissue disorders
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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PCT/JP2015/085962 WO2016104574A1 (fr) | 2014-12-24 | 2015-12-24 | Produits de prévention et/ou de traitement contre l'ossification ectopique et méthode de criblage de ces derniers |
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CA3013623A1 (fr) | 2016-02-05 | 2017-08-10 | Memorial Sloan-Ketering Cancer Center | Procedes de differenciation de precurseurs de lignees ectodermiques derives de cellules souches |
DE102016213684A1 (de) * | 2016-07-26 | 2018-02-01 | Tetec Tissue Engineering Technologies Ag | Marker und Verfahren zur Beurteilung der Zusammensetzung oder Reinheit einer Zellkultur sowie zur in vitro Bestimmung der Identität einer Knorpelzelle oder einer Synovialzelle |
WO2018199142A1 (fr) * | 2017-04-27 | 2018-11-01 | 国立大学法人京都大学 | Procédé de production de cellules de crête neurale et de neurones sympathiques |
WO2019051248A1 (fr) * | 2017-09-07 | 2019-03-14 | Memorial Sloan-Kettering Cancer Center | Procédés de différenciation de précurseurs de lignées ectodermiques dérivés de cellules souches |
CA3083253A1 (fr) * | 2017-11-30 | 2019-06-06 | Kyoto University | Methode de culture de cellules |
EP3842525A4 (fr) * | 2018-08-22 | 2022-07-27 | Kyoto University | Procédé de production d'une cellule précurseur de nerf du tractus intestinal |
WO2023106122A1 (fr) * | 2021-12-06 | 2023-06-15 | 国立大学法人京都大学 | Procédé de production de cellules de crête neurale spécialisées pour la différenciation en lignée mésenchymateuse |
CN115282261A (zh) * | 2022-08-16 | 2022-11-04 | 清远市人民医院 | 血小板衍生生长因子-bb在制备治疗骨关节炎药物中的应用 |
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