JP6669650B2 - 生殖能力のない魚及び卵生水生動物を作出する方法、ならびに卵及び胚内に化合物を送達する方法 - Google Patents

生殖能力のない魚及び卵生水生動物を作出する方法、ならびに卵及び胚内に化合物を送達する方法 Download PDF

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JP6669650B2
JP6669650B2 JP2016530195A JP2016530195A JP6669650B2 JP 6669650 B2 JP6669650 B2 JP 6669650B2 JP 2016530195 A JP2016530195 A JP 2016530195A JP 2016530195 A JP2016530195 A JP 2016530195A JP 6669650 B2 JP6669650 B2 JP 6669650B2
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fish
egg
morpholino oligomer
eggs
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ゾーハ,ヨナサン
ウォン,テン−ツァオ
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ユニバーシティ オブ メリーランド,ボルチモア カウンティ
ユニバーシティ オブ メリーランド,ボルチモア カウンティ
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K61/00Culture of aquatic animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/05Animals modified by non-integrating nucleic acids, e.g. antisense, RNAi, morpholino, episomal vector, for non-therapeutic purpose
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/40Fish
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • CCHEMISTRY; METALLURGY
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/323Chemical structure of the sugar modified ring structure
    • C12N2310/3233Morpholino-type ring
    • CCHEMISTRY; METALLURGY
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    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/40Monitoring or fighting invasive species

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  • Life Sciences & Earth Sciences (AREA)
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  • Zoology (AREA)
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  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)
JP2016530195A 2013-11-15 2014-11-14 生殖能力のない魚及び卵生水生動物を作出する方法、ならびに卵及び胚内に化合物を送達する方法 Active JP6669650B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201361904652P 2013-11-15 2013-11-15
US61/904,652 2013-11-15
US201461968458P 2014-03-21 2014-03-21
US61/968,458 2014-03-21
US201462050815P 2014-09-16 2014-09-16
US62/050,815 2014-09-16
PCT/US2014/065698 WO2015073819A1 (en) 2013-11-15 2014-11-14 Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos

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JP2017502651A JP2017502651A (ja) 2017-01-26
JP2017502651A5 JP2017502651A5 (enExample) 2018-02-22
JP6669650B2 true JP6669650B2 (ja) 2020-03-18

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US (3) US9999208B2 (enExample)
EP (1) EP3068216B1 (enExample)
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CN (1) CN105764333B (enExample)
AU (1) AU2014348473B2 (enExample)
CA (1) CA2929496C (enExample)
CL (1) CL2016001113A1 (enExample)
DK (1) DK180609B1 (enExample)
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FI (1) FI3068216T3 (enExample)
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NZ (1) NZ719421A (enExample)
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PT (1) PT3068216T (enExample)
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WO2015073819A1 (en) 2013-11-15 2015-05-21 University Of Maryland Baltimore County Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos
BR112017000925B1 (pt) 2014-07-14 2023-10-10 Washington State University Método de reprodução de porcos, método para gerar um porco sem nenhuma célula espermatogônica funcional, método de produção de um macho receptor e método de produção de porcos
RU2741645C2 (ru) * 2015-05-19 2021-01-28 Юниверсити Оф Мэрилэнд Балтимор Каунти Способы доставки агента в икринки рыб
CN106614142B (zh) * 2016-12-28 2019-12-03 浙江省海洋水产研究所 一种杂交不育黄姑鱼的生产方法
CN109864017A (zh) * 2017-12-05 2019-06-11 柳州市渔业技术推广站 山塘水库高产高效渔业养殖方法
PL3723479T3 (pl) * 2017-12-15 2024-10-07 Acd Pharmaceuticals As Sposoby produkcji sterylnych ryb
CN108668984B (zh) * 2018-04-15 2021-02-12 广西壮族自治区水产科学研究院 一种罗非鱼苗种高密度运输方法
CN108739537B (zh) * 2018-06-06 2021-02-09 江苏省淡水水产研究所 一种粉白体色斑点叉尾鮰家系制种方法
BR112021020349A2 (pt) * 2019-04-09 2021-12-14 Mayo Found Medical Education & Res Peixe estéril
CN112553205B (zh) * 2020-12-29 2022-09-13 中国水产科学研究院淡水渔业研究中心 一种抑制黄颡鱼性腺发育的反义rna序列组合和方法及应用
CN114982678B (zh) * 2022-07-21 2024-02-23 新疆额河生态养殖科技有限公司 一种北极茴鱼人工繁殖操作方法

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EP3068216A1 (en) 2016-09-21
MX369329B (es) 2019-11-05
AU2014348473B2 (en) 2018-06-14
PL3068216T3 (pl) 2024-10-14
BR112016011080A2 (pt) 2017-12-05
CA2929496C (en) 2022-08-23
EP3068216B1 (en) 2024-04-10
ES2981867T3 (es) 2024-10-10
WO2015073819A1 (en) 2015-05-21
CN105764333A (zh) 2016-07-13
DK201670401A1 (en) 2016-07-04
FI3068216T3 (fi) 2024-07-10
RU2016123427A (ru) 2017-12-20
CA2929496A1 (en) 2015-05-21
US9999208B2 (en) 2018-06-19
PT3068216T (pt) 2024-07-12
DK180609B1 (en) 2021-10-14
US20160286768A1 (en) 2016-10-06
US20190104710A1 (en) 2019-04-11
HRP20240918T1 (hr) 2024-10-11
EP3068216A4 (en) 2017-10-11
IL245293A0 (en) 2016-06-30
JP2017502651A (ja) 2017-01-26
MX2016006315A (es) 2017-01-19
NZ719421A (en) 2022-09-30
US20180288984A1 (en) 2018-10-11
CL2016001113A1 (es) 2017-01-06
CN105764333B (zh) 2021-09-03
US10136621B2 (en) 2018-11-27
AU2014348473A1 (en) 2016-05-19
RU2723037C2 (ru) 2020-06-08
IL245293B (en) 2020-04-30

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