MX369329B - Metodo para la produccion de peces infertiles y animales acuaticos productores de huevos y para la administracion de compuestos en huevos y embriones. - Google Patents

Metodo para la produccion de peces infertiles y animales acuaticos productores de huevos y para la administracion de compuestos en huevos y embriones.

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Publication number
MX369329B
MX369329B MX2016006315A MX2016006315A MX369329B MX 369329 B MX369329 B MX 369329B MX 2016006315 A MX2016006315 A MX 2016006315A MX 2016006315 A MX2016006315 A MX 2016006315A MX 369329 B MX369329 B MX 369329B
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MX
Mexico
Prior art keywords
compounds
producing
eggs
aquatic animals
egg
Prior art date
Application number
MX2016006315A
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English (en)
Other versions
MX2016006315A (es
Inventor
Zohar Yonathan
Tsao WONG Ten-
Original Assignee
Univ Maryland
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Publication date
Application filed by Univ Maryland filed Critical Univ Maryland
Publication of MX2016006315A publication Critical patent/MX2016006315A/es
Publication of MX369329B publication Critical patent/MX369329B/es

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0275Genetically modified vertebrates, e.g. transgenic
    • A01K67/0276Knock-out vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K61/00Culture of aquatic animals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00Modified animals
    • A01K2207/05Animals modified by non-integrating nucleic acids, e.g. antisense, RNAi, morpholino, episomal vector, for non-therapeutic purpose
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/07Animals genetically altered by homologous recombination
    • A01K2217/075Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/40Fish
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/11Antisense
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/323Chemical structure of the sugar modified ring structure
    • C12N2310/3233Morpholino-type ring
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/80Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in fisheries management
    • Y02A40/81Aquaculture, e.g. of fish
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/40Monitoring or fighting invasive species

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Veterinary Medicine (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Farming Of Fish And Shellfish (AREA)
  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)

Abstract

La presente invención se refiere a métodos para la producción de peces y animales acuáticos reproductivamente estériles para la acuicultura, el comercio de acuarios y el control de especies invasoras. Los métodos incluyen la alteración del desarrollo gonadal mediante la administración de compuestos que conducen a la falla en el desarrollo gonadal fértil. Los compuestos pueden ser administrados a los huevos antes de la fertilización o la activación en agua o después de la fertilización y la activación en agua contactando a los huevos no fertilizados o los huevos fertilizados previamente activados en agua o los huevos fertilizados con un medio de inmersión que incluye el compuesto de interés. Los compuestos pueden ser conjugados con un compuesto transportador molecular eficaz para el transporte coriónico del conjugado. Los compuestos pueden ser oligómeros de morfolino anti-sentidos que son capaces de suprimir con eficacia la expresión del gen dead end u otros genes esenciales para el desarrollo de la célula germinal en peces y otros animales acuáticos productores de huevo.
MX2016006315A 2013-11-15 2014-11-14 Metodo para la produccion de peces infertiles y animales acuaticos productores de huevos y para la administracion de compuestos en huevos y embriones. MX369329B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361904652P 2013-11-15 2013-11-15
US201461968458P 2014-03-21 2014-03-21
US201462050815P 2014-09-16 2014-09-16
PCT/US2014/065698 WO2015073819A1 (en) 2013-11-15 2014-11-14 Method of producing infertile fish and egg-producing aquatic animals and of delivering compounds into eggs and embryos

Publications (2)

Publication Number Publication Date
MX2016006315A MX2016006315A (es) 2017-01-19
MX369329B true MX369329B (es) 2019-11-05

Family

ID=53058068

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016006315A MX369329B (es) 2013-11-15 2014-11-14 Metodo para la produccion de peces infertiles y animales acuaticos productores de huevos y para la administracion de compuestos en huevos y embriones.

Country Status (18)

Country Link
US (3) US9999208B2 (es)
EP (1) EP3068216B1 (es)
JP (1) JP6669650B2 (es)
CN (1) CN105764333B (es)
AU (1) AU2014348473B2 (es)
CA (1) CA2929496C (es)
CL (1) CL2016001113A1 (es)
DK (1) DK180609B1 (es)
ES (1) ES2981867T3 (es)
FI (1) FI3068216T3 (es)
HR (1) HRP20240918T1 (es)
IL (1) IL245293B (es)
MX (1) MX369329B (es)
NZ (1) NZ719421A (es)
PL (1) PL3068216T3 (es)
PT (1) PT3068216T (es)
RU (1) RU2723037C2 (es)
WO (1) WO2015073819A1 (es)

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RU2723037C2 (ru) 2013-11-15 2020-06-08 Юниверсити Оф Мэриленд Балтимор Каунти Способ получения бесплодной рыбы и бесплодных производящих икру водных животных и способ доставки соединений в икру и эмбрионы
MX2017000555A (es) * 2014-07-14 2017-08-10 Univ Washington State Desactivacion de nanos que produce ablacion de celulas de linea germinal.
DK180094B1 (en) 2015-05-19 2020-04-27 University Of Maryland At Baltimore County METHODS OF ADMINISTRATION IN FISH EGGS AND EMBRYOS FOR PHARMACEUTICAL CREATION, MEDICINE TOXICITY ASSAY AND MANUFACTURE OF INFERTILE FISH.
CN106614142B (zh) * 2016-12-28 2019-12-03 浙江省海洋水产研究所 一种杂交不育黄姑鱼的生产方法
CN109864017A (zh) * 2017-12-05 2019-06-11 柳州市渔业技术推广站 山塘水库高产高效渔业养殖方法
FI3723479T3 (fi) 2017-12-15 2024-08-21 Acd Pharmaceuticals As Steriilien kalojen tuotantomenetelmät
CN108668984B (zh) * 2018-04-15 2021-02-12 广西壮族自治区水产科学研究院 一种罗非鱼苗种高密度运输方法
CN108739537B (zh) * 2018-06-06 2021-02-09 江苏省淡水水产研究所 一种粉白体色斑点叉尾鮰家系制种方法
CN112553205B (zh) * 2020-12-29 2022-09-13 中国水产科学研究院淡水渔业研究中心 一种抑制黄颡鱼性腺发育的反义rna序列组合和方法及应用
CN114982678B (zh) * 2022-07-21 2024-02-23 新疆额河生态养殖科技有限公司 一种北极茴鱼人工繁殖操作方法

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DK180094B1 (en) 2015-05-19 2020-04-27 University Of Maryland At Baltimore County METHODS OF ADMINISTRATION IN FISH EGGS AND EMBRYOS FOR PHARMACEUTICAL CREATION, MEDICINE TOXICITY ASSAY AND MANUFACTURE OF INFERTILE FISH.

Also Published As

Publication number Publication date
DK180609B1 (en) 2021-10-14
US10136621B2 (en) 2018-11-27
CA2929496C (en) 2022-08-23
MX2016006315A (es) 2017-01-19
PL3068216T3 (pl) 2024-10-14
FI3068216T3 (fi) 2024-07-10
CN105764333B (zh) 2021-09-03
US20190104710A1 (en) 2019-04-11
AU2014348473A1 (en) 2016-05-19
US9999208B2 (en) 2018-06-19
AU2014348473B2 (en) 2018-06-14
JP6669650B2 (ja) 2020-03-18
US20160286768A1 (en) 2016-10-06
EP3068216A1 (en) 2016-09-21
US20180288984A1 (en) 2018-10-11
CN105764333A (zh) 2016-07-13
HRP20240918T1 (hr) 2024-10-11
EP3068216B1 (en) 2024-04-10
CA2929496A1 (en) 2015-05-21
NZ719421A (en) 2022-09-30
ES2981867T3 (es) 2024-10-10
WO2015073819A1 (en) 2015-05-21
EP3068216A4 (en) 2017-10-11
JP2017502651A (ja) 2017-01-26
DK201670401A1 (en) 2016-07-04
RU2723037C2 (ru) 2020-06-08
IL245293A0 (en) 2016-06-30
CL2016001113A1 (es) 2017-01-06
PT3068216T (pt) 2024-07-12
IL245293B (en) 2020-04-30
RU2016123427A (ru) 2017-12-20
BR112016011080A2 (pt) 2017-12-05

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