JP6637961B2 - Ｍｙｈ７ｂの阻害剤およびその使用 - Google Patents
Ｍｙｈ７ｂの阻害剤およびその使用 Download PDFInfo
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- JP6637961B2 JP6637961B2 JP2017506382A JP2017506382A JP6637961B2 JP 6637961 B2 JP6637961 B2 JP 6637961B2 JP 2017506382 A JP2017506382 A JP 2017506382A JP 2017506382 A JP2017506382 A JP 2017506382A JP 6637961 B2 JP6637961 B2 JP 6637961B2
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- Prior art keywords
- antisense oligonucleotide
- nucleotides
- myh7b
- sequence
- inhibitor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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| GB2547586A (en) * | 2014-08-20 | 2017-08-23 | Lifesplice Pharma Llc | Splice modulating oligonucleotides and methods of use thereof(In the PCT request) |
| WO2017201422A1 (en) | 2016-05-20 | 2017-11-23 | The General Hospital Corporation | Using micrornas to control activation status of hepatic stellate cells and to prevent fibrosis in progressive liver diseases |
| JP2019535839A (ja) | 2016-11-29 | 2019-12-12 | ピュアテック ヘルス エルエルシー | 治療剤の送達のためのエクソソーム |
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| EP3813844A1 (en) * | 2018-06-28 | 2021-05-05 | United Kingdom Research and Innovation | Treatment of cardiomyopathy through modulation of hypoxia-induced erna activity |
| US20210324101A1 (en) * | 2018-08-02 | 2021-10-21 | Dyne Therapeutics, Inc. | Muscle targeting complexes and uses thereof for treating hypertrophic cardiomyopathy |
| US12018087B2 (en) | 2018-08-02 | 2024-06-25 | Dyne Therapeutics, Inc. | Muscle-targeting complexes comprising an anti-transferrin receptor antibody linked to an oligonucleotide and methods of delivering oligonucleotide to a subject |
| EA202190416A1 (ru) | 2018-08-02 | 2021-06-23 | Дайн Терапьютикс, Инк. | Мышечно-специфические комлексы и их применение для лечения плече-лопаточно-лицевой мышечной дистрофии |
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