JP6595592B2 - 完全型免疫グロブリン形態の抗体を細胞膜を透過して細胞質に位置させる方法およびその利用 - Google Patents
完全型免疫グロブリン形態の抗体を細胞膜を透過して細胞質に位置させる方法およびその利用 Download PDFInfo
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| Application Number | Priority Date | Filing Date | Title |
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| KR20140092673 | 2014-07-22 | ||
| KR10-2014-0092673 | 2014-07-22 | ||
| KR1020150103163A KR101602870B1 (ko) | 2014-07-22 | 2015-07-21 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR10-2015-0103163 | 2015-07-21 | ||
| PCT/KR2015/007626 WO2016013870A1 (ko) | 2014-07-22 | 2015-07-22 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
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| JP2017529097A JP2017529097A (ja) | 2017-10-05 |
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| WO2012135831A1 (en) | 2011-04-01 | 2012-10-04 | Yale University | Cell-penetrating anti-dna antibodies and uses thereof inhibit dna repair |
| KR101602876B1 (ko) | 2014-07-22 | 2016-03-11 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| KR101602870B1 (ko) | 2014-07-22 | 2016-03-21 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR102000000B1 (ko) * | 2016-05-27 | 2019-07-12 | 오름테라퓨틱 주식회사 | 항체에 엔도좀 탈출능을 부여하는 엔도좀 탈출 구조 모티프 및 이의 활용 |
| JP2019520086A (ja) | 2016-05-27 | 2019-07-18 | オラム・セラピューティクス・インコーポレイテッド | 細胞質浸透抗体およびその用途 |
| WO2017218824A1 (en) | 2016-06-15 | 2017-12-21 | Yale University | Anti-guanosine antibody as a molecular delivery vehicle |
| WO2017218825A1 (en) | 2016-06-15 | 2017-12-21 | Yale University | Antibody-mediated autocatalytic, targeted delivery of nanocarriers to tumors |
| WO2019107812A1 (ko) | 2017-11-16 | 2019-06-06 | 오름테라퓨틱 주식회사 | 세포의 세포질에 침투하여 세포내 활성화된 ras를 억제하는 항체 및 이의 용도 |
| US12304970B2 (en) | 2018-02-01 | 2025-05-20 | Yale University | Nuclear localization signals, compositions formed therefrom, and methods of use thereof for delivery of cargo to the nucleus |
| CN112218621A (zh) * | 2018-04-10 | 2021-01-12 | 西北大学 | 包含基于靶向亲和域的膜蛋白的胞外囊泡 |
| US10787487B2 (en) | 2018-06-21 | 2020-09-29 | Orum Therapeutics Inc. | Cell/tissue-specific cell-penetrating antibodies |
| JP2021532135A (ja) * | 2018-07-23 | 2021-11-25 | 中外製薬株式会社 | 標的細胞特異的な細胞質侵入抗原結合分子 |
| CN110759996B (zh) * | 2018-07-27 | 2022-09-06 | 深圳康体生命科技有限公司 | 一种gfp抗体 |
| CN108949565B (zh) * | 2018-09-26 | 2024-09-06 | 中国科学技术大学 | 用于红细胞负载冻干保护剂的装置及方法 |
| CN113825515A (zh) * | 2019-05-01 | 2021-12-21 | 圣地亚哥德孔波斯特拉大学 | 调配成纳米胶囊的抗kras抗体的胞内递送 |
| US20230076637A1 (en) | 2020-02-06 | 2023-03-09 | Ajou University Industry-Academic Cooperation Foundation | Fusion antibody for presenting antigen-derived t cell antigen epitope or peptide containing same on cell surface, and composition comprising same |
| WO2021170684A1 (en) * | 2020-02-24 | 2021-09-02 | Oblique Therapeutics Ab | Kras epitopes and antibodies |
| PE20231504A1 (es) * | 2020-04-30 | 2023-09-26 | Genentech Inc | Anticuerpos especificos para kras y sus usos |
| KR102623211B1 (ko) | 2021-07-20 | 2024-01-11 | 아주대학교산학협력단 | 세포 내부에 침투하여 표적단백질을 분해하여 제거하는 세포침투 분해항체 및 이의 용도 |
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| US9283272B2 (en) | 2012-03-30 | 2016-03-15 | The United States Of America As Represented By The Department Of Veterans Affairs | Targeting intracellular target-binding determinants with intracellular antibodies |
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| KR101602876B1 (ko) | 2014-07-22 | 2016-03-11 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| KR101602870B1 (ko) | 2014-07-22 | 2016-03-21 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
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| JP2019520086A (ja) | 2016-05-27 | 2019-07-18 | オラム・セラピューティクス・インコーポレイテッド | 細胞質浸透抗体およびその用途 |
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| WO2019107812A1 (ko) | 2017-11-16 | 2019-06-06 | 오름테라퓨틱 주식회사 | 세포의 세포질에 침투하여 세포내 활성화된 ras를 억제하는 항체 및 이의 용도 |
| US10787487B2 (en) | 2018-06-21 | 2020-09-29 | Orum Therapeutics Inc. | Cell/tissue-specific cell-penetrating antibodies |
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- 2015-07-22 JP JP2017525495A patent/JP6595592B2/ja not_active Expired - Fee Related
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| US20170218084A1 (en) | 2017-08-03 |
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| KR101602870B1 (ko) | 2016-03-21 |
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| CA2955272A1 (en) | 2016-01-28 |
| AU2015292955B2 (en) | 2020-08-13 |
| BR112017001304A2 (pt) | 2018-01-30 |
| RU2017103675A (ru) | 2018-08-06 |
| EP3173428A1 (en) | 2017-05-31 |
| JP2017529097A (ja) | 2017-10-05 |
| IL250203B (en) | 2020-09-30 |
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