JP6595592B2 - 完全型免疫グロブリン形態の抗体を細胞膜を透過して細胞質に位置させる方法およびその利用 - Google Patents
完全型免疫グロブリン形態の抗体を細胞膜を透過して細胞質に位置させる方法およびその利用 Download PDFInfo
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2014-0092673 | 2014-07-22 | ||
| KR20140092673 | 2014-07-22 | ||
| KR1020150103163A KR101602870B1 (ko) | 2014-07-22 | 2015-07-21 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR10-2015-0103163 | 2015-07-21 | ||
| PCT/KR2015/007626 WO2016013870A1 (ko) | 2014-07-22 | 2015-07-22 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
Publications (3)
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| JP2017529097A JP2017529097A (ja) | 2017-10-05 |
| JP2017529097A5 JP2017529097A5 (OSRAM) | 2018-08-30 |
| JP6595592B2 true JP6595592B2 (ja) | 2019-10-23 |
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| JP2017525495A Expired - Fee Related JP6595592B2 (ja) | 2014-07-22 | 2015-07-22 | 完全型免疫グロブリン形態の抗体を細胞膜を透過して細胞質に位置させる方法およびその利用 |
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| EP (1) | EP3173428B1 (OSRAM) |
| JP (1) | JP6595592B2 (OSRAM) |
| KR (1) | KR101602870B1 (OSRAM) |
| CN (1) | CN107001481A (OSRAM) |
| AU (1) | AU2015292955B2 (OSRAM) |
| BR (1) | BR112017001304A2 (OSRAM) |
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| IL (1) | IL250203B (OSRAM) |
| RU (1) | RU2017103675A (OSRAM) |
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| US9701740B2 (en) | 2011-04-01 | 2017-07-11 | Yale University | Cell-penetrating anti-DNA antibodies and uses thereof inhibit DNA repair |
| KR101602870B1 (ko) | 2014-07-22 | 2016-03-21 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR101602876B1 (ko) | 2014-07-22 | 2016-03-11 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| MX2018014554A (es) | 2016-05-27 | 2019-09-09 | Orum Therapeutics Inc | Anticuerpo penetrante de citosol y uso del mismo. |
| KR102000000B1 (ko) * | 2016-05-27 | 2019-07-12 | 오름테라퓨틱 주식회사 | 항체에 엔도좀 탈출능을 부여하는 엔도좀 탈출 구조 모티프 및 이의 활용 |
| WO2017218824A1 (en) | 2016-06-15 | 2017-12-21 | Yale University | Anti-guanosine antibody as a molecular delivery vehicle |
| EP3471777A1 (en) | 2016-06-15 | 2019-04-24 | Yale University | Antibody-mediated autocatalytic, targeted delivery of nanocarriers to tumors |
| EP3712180A4 (en) | 2017-11-16 | 2021-08-11 | Orum Therapeutics Inc. | RAS INHIBITOR ANTIBODIES ACTIVATED IN A CELL BY INTERNALIZATION IN CYTOSOL OF THE CELL, AND ITS USE |
| WO2019152806A1 (en) * | 2018-02-01 | 2019-08-08 | Yale University | Compositions and methods for enhancing nuclear translocation |
| JP7416433B2 (ja) * | 2018-04-10 | 2024-01-17 | ノースウェスタン ユニバーシティ | 標的指向性親和性ドメインに基づく膜タンパク質を含む細胞外小胞 |
| KR20190143826A (ko) * | 2018-06-21 | 2019-12-31 | 오름테라퓨틱 주식회사 | 세포/조직 특이적 세포 침투 항체 |
| WO2020022262A1 (en) * | 2018-07-23 | 2020-01-30 | Chugai Seiyaku Kabushiki Kaisha | Target cell specific cytosol-penetrating antigen-binding molecules |
| CN110759996B (zh) * | 2018-07-27 | 2022-09-06 | 深圳康体生命科技有限公司 | 一种gfp抗体 |
| CN108949565B (zh) * | 2018-09-26 | 2024-09-06 | 中国科学技术大学 | 用于红细胞负载冻干保护剂的装置及方法 |
| WO2020221849A1 (en) * | 2019-05-01 | 2020-11-05 | Universidade De Santiago De Compostela | Intracellular delivery of anti-kras antibodies formulated into nanocapsules |
| US20230076637A1 (en) | 2020-02-06 | 2023-03-09 | Ajou University Industry-Academic Cooperation Foundation | Fusion antibody for presenting antigen-derived t cell antigen epitope or peptide containing same on cell surface, and composition comprising same |
| BR112022016643A2 (pt) * | 2020-02-24 | 2022-10-11 | Oblique Therapeutics Ab | Epítopos e anticorpos contra kras |
| WO2021222333A1 (en) * | 2020-04-30 | 2021-11-04 | Genentech, Inc. | Kras specific antibodies and uses thereof |
| US20240352100A1 (en) * | 2021-07-20 | 2024-10-24 | Ajou University Industry-Academic Cooperation Foundation | Cell-penetrating degrading antibody that penetrates into cells to degrade and remove target protein and use thereof |
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| CN101448848B (zh) | 2006-03-27 | 2013-12-04 | 全球免疫股份有限公司 | Ras突变及其相关组合物和方法 |
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| KR100849941B1 (ko) * | 2008-04-29 | 2008-08-01 | 원우이에프엔지니어링주식회사 | 열 및 연기 화재감지장치 복합시험기 |
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| US9283272B2 (en) | 2012-03-30 | 2016-03-15 | The United States Of America As Represented By The Department Of Veterans Affairs | Targeting intracellular target-binding determinants with intracellular antibodies |
| US9815866B2 (en) | 2012-09-14 | 2017-11-14 | Japanese Foundation For Cancer Research | Peptides that bind to epithelial cell adhesion molecule |
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| KR101602870B1 (ko) | 2014-07-22 | 2016-03-21 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 항체를 세포막을 투과하여 세포질에 위치시키는 방법 및 그의 이용 |
| KR101602876B1 (ko) | 2014-07-22 | 2016-03-11 | 아주대학교산학협력단 | 완전한 이뮤노글로불린 형태의 세포질 침투능을 갖는 항체를 이용하여 세포내 활성화된 ras를 억제하는 방법 및 그의 이용 |
| KR102721595B1 (ko) | 2015-04-03 | 2024-10-23 | 유레카 쎄라퓨틱스, 인코포레이티드 | Afp 펩티드/mhc 복합체를 표적화하는 구축물 및 그의 용도 |
| KR101790669B1 (ko) | 2015-10-14 | 2017-10-26 | 아주대학교산학협력단 | 개선된 분할 녹색 형광 단백질 상보 시스템 및 이의 용도 |
| MX2018014554A (es) | 2016-05-27 | 2019-09-09 | Orum Therapeutics Inc | Anticuerpo penetrante de citosol y uso del mismo. |
| KR101836392B1 (ko) | 2016-08-17 | 2018-03-08 | 한림대학교 산학협력단 | 사이클릭 펩타이드를 포함하는 백신 조성물, 사이클릭 펩타이드에 대한 항체 또는 이를 포함하는 항암 조성물 |
| EP3712180A4 (en) | 2017-11-16 | 2021-08-11 | Orum Therapeutics Inc. | RAS INHIBITOR ANTIBODIES ACTIVATED IN A CELL BY INTERNALIZATION IN CYTOSOL OF THE CELL, AND ITS USE |
| KR20190143826A (ko) | 2018-06-21 | 2019-12-31 | 오름테라퓨틱 주식회사 | 세포/조직 특이적 세포 침투 항체 |
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| EP3173428A4 (en) | 2018-01-24 |
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| IL250203B (en) | 2020-09-30 |
| EP3173428B1 (en) | 2020-02-19 |
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| AU2015292955B2 (en) | 2020-08-13 |
| US20170218084A1 (en) | 2017-08-03 |
| EP3173428A1 (en) | 2017-05-31 |
| IL250203A0 (en) | 2017-03-30 |
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