JP6588893B2 - 卵巣がんの自己抗体バイオマーカー - Google Patents
卵巣がんの自己抗体バイオマーカー Download PDFInfo
- Publication number
- JP6588893B2 JP6588893B2 JP2016515521A JP2016515521A JP6588893B2 JP 6588893 B2 JP6588893 B2 JP 6588893B2 JP 2016515521 A JP2016515521 A JP 2016515521A JP 2016515521 A JP2016515521 A JP 2016515521A JP 6588893 B2 JP6588893 B2 JP 6588893B2
- Authority
- JP
- Japan
- Prior art keywords
- ovarian cancer
- autoantibodies
- autoantibody
- subject
- anxa1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rehabilitation Therapy (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2013903595 | 2013-09-18 | ||
| AU2013903595A AU2013903595A0 (en) | 2013-09-18 | Autoantibody biomarkers of ovarian cancer | |
| PCT/AU2014/000925 WO2015039175A1 (en) | 2013-09-18 | 2014-09-18 | Autoantibody biomarkers of ovarian cancer |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016536568A JP2016536568A (ja) | 2016-11-24 |
| JP2016536568A5 JP2016536568A5 (enExample) | 2017-10-26 |
| JP6588893B2 true JP6588893B2 (ja) | 2019-10-09 |
Family
ID=52687999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016515521A Active JP6588893B2 (ja) | 2013-09-18 | 2014-09-18 | 卵巣がんの自己抗体バイオマーカー |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US20160291025A1 (enExample) |
| EP (1) | EP3047277B1 (enExample) |
| JP (1) | JP6588893B2 (enExample) |
| CN (1) | CN105745543B (enExample) |
| AU (1) | AU2014324080B2 (enExample) |
| CA (1) | CA2924600A1 (enExample) |
| WO (1) | WO2015039175A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107056888A (zh) * | 2017-03-01 | 2017-08-18 | 中山大学肿瘤防治中心 | Atp1a1靶向多肽及应用 |
| CN109116024B (zh) * | 2018-06-14 | 2021-04-23 | 郑州大学第一附属医院 | 一种肺癌标志物抗-actr3自身抗体及其应用 |
| GB201813137D0 (en) | 2018-08-10 | 2018-09-26 | Medannex Ltd | Cancer treatment with an antibody |
| CN109182260A (zh) * | 2018-09-11 | 2019-01-11 | 邵勇 | 一种体外培养胎膜间充质干细胞的方法 |
| CN109480771B (zh) * | 2018-10-17 | 2021-09-07 | 江西惠肽生物科技有限公司 | 一种卵巢肿块良恶的确定方法及确定装置 |
| CN113785199B (zh) * | 2019-03-01 | 2024-02-09 | 先进标志物探索公司 | 用于诊断结肠直肠癌和/或其癌前阶段的蛋白质特征 |
| AU2020368546A1 (en) * | 2019-10-16 | 2022-05-26 | Icahn School Of Medicine At Mount Sinai | Systems and methods for detecting a disease condition |
| US12152280B2 (en) | 2021-09-20 | 2024-11-26 | Droplet Biosciences, Inc. | Drain fluid for diagnostics |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1161262B1 (en) * | 1999-03-15 | 2008-05-21 | University of Maryland, Baltimore | SURFACE LOCALIZED COLLIGIN/HsP47 IN CARCINOMA CELLS |
| US6645465B2 (en) * | 1999-08-06 | 2003-11-11 | Michigan, University Of The Regents | Annexin proteins and autoantibodies as serum markers for cancer |
| US20020037286A1 (en) * | 2000-04-03 | 2002-03-28 | Matthias Krause | Methods for altering T cell and macrophage activation |
| US8614169B2 (en) * | 2001-12-04 | 2013-12-24 | Wayne State University | Neoepitope detection of disease using protein arrays |
| EP1540010B8 (en) * | 2002-08-06 | 2010-07-14 | The Johns Hopkins University | Use of biomarkers for detecting ovarian cancer |
| CN101268367A (zh) * | 2005-06-24 | 2008-09-17 | 赛弗吉生物系统公司 | 卵巢癌的生物标记 |
| AU2007211085A1 (en) * | 2006-01-27 | 2007-08-09 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
| AU2007297310B2 (en) | 2006-09-13 | 2013-11-07 | Oncimmune Limited | Improved immunoassay methods |
| WO2008115710A2 (en) * | 2007-03-07 | 2008-09-25 | The Johns Hopkins University | Biomarkers for cancer |
| JP5265140B2 (ja) * | 2007-06-14 | 2013-08-14 | 学校法人日本医科大学 | 卵巣癌の検出方法及び検出用キット |
| EP2637020A3 (en) * | 2007-06-29 | 2014-01-08 | Correlogic Systems Inc. | Predictive markers for ovarian cancer |
| RU2571687C2 (ru) * | 2007-11-13 | 2015-12-20 | Феникс Байотекнолоджи Инк. | Набор для определения вероятности терапевтического ответа на противораковую химиотерапию сердечным гликозидом |
| EP2277049A4 (en) * | 2008-05-09 | 2012-05-30 | Univ Duke | AUTOANTIKÖRPER FOR THE PROOF AND THE TREATMENT OF CANCER |
| US20120046181A1 (en) * | 2008-12-19 | 2012-02-23 | Chu Nantes | Biomarkers for the Diagnosis of Renal Allograft and Kidney Status |
| US20120004289A1 (en) * | 2009-03-06 | 2012-01-05 | The Johns Hopkins University | Annexin a11 and associated genes as biomarkers for cancer |
| CN101762699A (zh) * | 2009-06-24 | 2010-06-30 | 北京科美东雅生物技术有限公司 | 一种定量检测血液中肿瘤相关抗原125的磁性免疫层析试纸条及制备方法 |
| US20120277326A1 (en) | 2009-11-20 | 2012-11-01 | Taylor Douglas D | Biomarkers of cancer |
| JP2011257147A (ja) * | 2010-06-04 | 2011-12-22 | Nitto Boseki Co Ltd | データ収集方法、キット及び腫瘍マーカー |
| WO2013112801A1 (en) * | 2012-01-26 | 2013-08-01 | Ibc Pharmaceuticals, Inc. | Targeting interferon-lambda with antibodies potently enhances anti-tumor and anti-viral activities |
| CN102590531A (zh) * | 2012-03-24 | 2012-07-18 | 广西壮族自治区肿瘤防治研究所 | 卵巢癌相关抗原自身抗体谱液相芯片检测试剂盒及其制备方法 |
| JP5574348B2 (ja) * | 2012-05-31 | 2014-08-20 | 国立大学法人 千葉大学 | 肺サルコイドーシスおよび眼サルコイドーシスの検出マーカー及び検出キット |
| US20140179808A1 (en) * | 2012-10-23 | 2014-06-26 | Bio-Rad Laboratories, Inc. | Detection of Ovarian Carcinoma by Assay for Autoantibodies to Multiple Antigens |
| EP2951592A4 (en) | 2013-01-31 | 2017-01-04 | Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University | Autoantibody signature for the early detection of ovarian cancer |
-
2014
- 2014-09-18 CN CN201480063118.7A patent/CN105745543B/zh active Active
- 2014-09-18 CA CA2924600A patent/CA2924600A1/en not_active Abandoned
- 2014-09-18 AU AU2014324080A patent/AU2014324080B2/en active Active
- 2014-09-18 WO PCT/AU2014/000925 patent/WO2015039175A1/en not_active Ceased
- 2014-09-18 EP EP14846089.2A patent/EP3047277B1/en active Active
- 2014-09-18 JP JP2016515521A patent/JP6588893B2/ja active Active
- 2014-09-18 US US15/023,155 patent/US20160291025A1/en not_active Abandoned
-
2019
- 2019-01-11 US US16/245,822 patent/US11371993B2/en active Active
-
2022
- 2022-05-27 US US17/826,948 patent/US12287337B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20220365088A1 (en) | 2022-11-17 |
| WO2015039175A1 (en) | 2015-03-26 |
| US12287337B2 (en) | 2025-04-29 |
| CN105745543A (zh) | 2016-07-06 |
| US20160291025A1 (en) | 2016-10-06 |
| JP2016536568A (ja) | 2016-11-24 |
| AU2014324080B2 (en) | 2020-07-23 |
| EP3047277A1 (en) | 2016-07-27 |
| US20190219584A1 (en) | 2019-07-18 |
| EP3047277A4 (en) | 2017-05-10 |
| CA2924600A1 (en) | 2015-03-26 |
| AU2014324080A1 (en) | 2016-04-14 |
| CN105745543B (zh) | 2018-02-02 |
| EP3047277B1 (en) | 2018-11-21 |
| US11371993B2 (en) | 2022-06-28 |
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