JP6572130B2 - 内皮機能不全及び炎症の疾患の治療 - Google Patents

内皮機能不全及び炎症の疾患の治療 Download PDF

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JP6572130B2
JP6572130B2 JP2015546770A JP2015546770A JP6572130B2 JP 6572130 B2 JP6572130 B2 JP 6572130B2 JP 2015546770 A JP2015546770 A JP 2015546770A JP 2015546770 A JP2015546770 A JP 2015546770A JP 6572130 B2 JP6572130 B2 JP 6572130B2
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JP2016504311A5 (enExample
JP2016504311A (ja
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グレゴリー キンプトン、ウェイン
グレゴリー キンプトン、ウェイン
リーヴズ ベイリー、サイモン
リーヴズ ベイリー、サイモン
イテシュー、シルビウ
ゴーシュ、ピーター
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メソブラスト、インコーポレイテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0662—Stem cells
    • C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
JP2015546770A 2012-12-12 2013-12-12 内皮機能不全及び炎症の疾患の治療 Active JP6572130B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261736361P 2012-12-12 2012-12-12
US61/736,361 2012-12-12
PCT/AU2013/001452 WO2014089623A1 (en) 2012-12-12 2013-12-12 Treatment of diseases of endothelial dysfunction and inflammation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019123243A Division JP6829288B2 (ja) 2012-12-12 2019-07-01 内皮機能不全及び炎症の疾患の治療

Publications (3)

Publication Number Publication Date
JP2016504311A JP2016504311A (ja) 2016-02-12
JP2016504311A5 JP2016504311A5 (enExample) 2017-01-19
JP6572130B2 true JP6572130B2 (ja) 2019-09-04

Family

ID=50933585

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2015546770A Active JP6572130B2 (ja) 2012-12-12 2013-12-12 内皮機能不全及び炎症の疾患の治療
JP2019123243A Active JP6829288B2 (ja) 2012-12-12 2019-07-01 内皮機能不全及び炎症の疾患の治療
JP2021008250A Active JP7201715B2 (ja) 2012-12-12 2021-01-21 内皮機能不全及び炎症の疾患の治療
JP2022206042A Pending JP2023030116A (ja) 2012-12-12 2022-12-22 内皮機能不全及び炎症の疾患の治療
JP2024111736A Pending JP2024147655A (ja) 2012-12-12 2024-07-11 内皮機能不全及び炎症の疾患の治療

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JP2019123243A Active JP6829288B2 (ja) 2012-12-12 2019-07-01 内皮機能不全及び炎症の疾患の治療
JP2021008250A Active JP7201715B2 (ja) 2012-12-12 2021-01-21 内皮機能不全及び炎症の疾患の治療
JP2022206042A Pending JP2023030116A (ja) 2012-12-12 2022-12-22 内皮機能不全及び炎症の疾患の治療
JP2024111736A Pending JP2024147655A (ja) 2012-12-12 2024-07-11 内皮機能不全及び炎症の疾患の治療

Country Status (11)

Country Link
US (2) US20160175360A1 (enExample)
EP (2) EP2931876B1 (enExample)
JP (5) JP6572130B2 (enExample)
KR (3) KR102217962B1 (enExample)
CN (2) CN105358163B (enExample)
AU (4) AU2013360024B2 (enExample)
CA (1) CA2893942C (enExample)
ES (1) ES2742035T3 (enExample)
IL (1) IL239308A0 (enExample)
SG (2) SG11201504340YA (enExample)
WO (1) WO2014089623A1 (enExample)

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* Cited by examiner, † Cited by third party
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KR101995016B1 (ko) 2007-12-04 2019-06-28 프로테오바이오엑티브스 피티와이 엘티디 전구 세포의 보호 및 그의 분화 조절
SG11201504340YA (en) * 2012-12-12 2015-07-30 Mesoblast Inc Treatment of diseases of endothelial dysfunction and inflammation
WO2022114111A1 (ja) * 2020-11-27 2022-06-02 マルホ株式会社 医薬品又は化粧品用組成物

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US5173414A (en) 1990-10-30 1992-12-22 Applied Immune Sciences, Inc. Production of recombinant adeno-associated virus vectors
ATE237694T1 (de) 1991-08-20 2003-05-15 Us Gov Health & Human Serv Adenovirus vermittelter gentransfer in den gastrointestinaltrakt
WO1998043630A1 (en) * 1997-04-02 1998-10-08 Brigham And Women's Hospital, Inc. Means of ascertaining an individual's risk profile for atherosclerotic disease
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AUPQ147799A0 (en) 1999-07-07 1999-07-29 Medvet Science Pty. Ltd. Mesenchymal precursor cell
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US20080095749A1 (en) * 2004-03-22 2008-04-24 Sudeepta Aggarwal Mesenchymal stem cells and uses therefor
TR201900968T4 (tr) 2004-09-24 2019-02-21 Mesoblast Inc Multipotansiyel genleşmiş mezenkimal prekürsör hücre soyu (memp) ve bunların kullanımı.
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Also Published As

Publication number Publication date
CA2893942A1 (en) 2014-06-19
SG10201705061RA (en) 2017-07-28
KR102367981B1 (ko) 2022-02-25
EP2931876A1 (en) 2015-10-21
IL239308A0 (en) 2015-07-30
AU2019202960B2 (en) 2021-07-29
HK1210209A1 (en) 2016-04-15
CA2893942C (en) 2023-03-28
KR102506612B1 (ko) 2023-03-06
WO2014089623A1 (en) 2014-06-19
US20240115618A1 (en) 2024-04-11
KR102217962B1 (ko) 2021-02-22
JP2019214571A (ja) 2019-12-19
KR20220029758A (ko) 2022-03-08
AU2019202960A1 (en) 2019-05-16
EP2931876B1 (en) 2019-05-29
KR20150093732A (ko) 2015-08-18
EP3556850A1 (en) 2019-10-23
CN105358163A (zh) 2016-02-24
AU2024227208A1 (en) 2024-10-31
AU2013360024B2 (en) 2019-02-28
CN105358163B (zh) 2020-09-11
CN111840329B (zh) 2024-10-15
JP2016504311A (ja) 2016-02-12
ES2742035T3 (es) 2020-02-12
JP6829288B2 (ja) 2021-02-10
AU2021250848A1 (en) 2021-11-04
JP2023030116A (ja) 2023-03-07
KR20210021104A (ko) 2021-02-24
JP7201715B2 (ja) 2023-01-10
US20160175360A1 (en) 2016-06-23
SG11201504340YA (en) 2015-07-30
JP2021073240A (ja) 2021-05-13
JP2024147655A (ja) 2024-10-16
CN111840329A (zh) 2020-10-30
AU2013360024A1 (en) 2015-07-02
EP2931876A4 (en) 2016-05-25

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