JP6567549B2 - 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム - Google Patents

光学検出によるポイントオブケア凝固アッセイのための方法及びシステム Download PDF

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JP6567549B2
JP6567549B2 JP2016564011A JP2016564011A JP6567549B2 JP 6567549 B2 JP6567549 B2 JP 6567549B2 JP 2016564011 A JP2016564011 A JP 2016564011A JP 2016564011 A JP2016564011 A JP 2016564011A JP 6567549 B2 JP6567549 B2 JP 6567549B2
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reaction chamber
optical
assay system
optical reference
excitation light
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JP2017519189A (ja
JP2017519189A5 (enExample
Inventor
ケリモ，ジョゼフ
ツェン，ハンソン
シャルラック，ロン
ブランケンスタイン，ゲルト
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インストゥルメンテーション ラボラトリー カンパニー
インストゥルメンテーション ラボラトリー カンパニー
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G01N21/534—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke by measuring transmission alone, i.e. determining opacity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/063—Illuminating optical parts
    • G01N2201/0636—Reflectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2016564011A 2014-04-30 2015-04-27 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム Active JP6567549B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461986475P 2014-04-30 2014-04-30
US61/986,475 2014-04-30
PCT/US2015/027715 WO2015167983A1 (en) 2014-04-30 2015-04-27 Methods and systems for point-of-care coagulation assays by optical detection

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019140602A Division JP2019194622A (ja) 2014-04-30 2019-07-31 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム

Publications (3)

Publication Number Publication Date
JP2017519189A JP2017519189A (ja) 2017-07-13
JP2017519189A5 JP2017519189A5 (enExample) 2017-10-12
JP6567549B2 true JP6567549B2 (ja) 2019-08-28

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JP2016564011A Active JP6567549B2 (ja) 2014-04-30 2015-04-27 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム
JP2019140602A Pending JP2019194622A (ja) 2014-04-30 2019-07-31 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム

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JP2019140602A Pending JP2019194622A (ja) 2014-04-30 2019-07-31 光学検出によるポイントオブケア凝固アッセイのための方法及びシステム

Country Status (7)

Country Link
US (2) US11079325B2 (enExample)
EP (1) EP3137878A1 (enExample)
JP (2) JP6567549B2 (enExample)
CN (2) CN110554007A (enExample)
AU (1) AU2015253478C1 (enExample)
CA (1) CA2946877C (enExample)
WO (1) WO2015167983A1 (enExample)

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WO2021195120A1 (en) * 2020-03-24 2021-09-30 In Diagnostics, Inc. Clinical spectrophotometer for general chemistry, immuno-assay and nucleic acid detection
WO2022054921A1 (en) * 2020-09-11 2022-03-17 Atonarp Inc. System including auto-alignment
US12036344B2 (en) * 2020-11-13 2024-07-16 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
CN115201498A (zh) * 2021-04-13 2022-10-18 基蛋生物科技股份有限公司 一种用于凝血检测的试剂卡及检测仪器

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Also Published As

Publication number Publication date
CA2946877C (en) 2021-02-09
CN106605144B (zh) 2019-09-27
CA2946877A1 (en) 2015-11-05
AU2015253478B2 (en) 2018-04-26
AU2015253478A1 (en) 2016-11-17
AU2015253478C1 (en) 2019-01-17
CN110554007A (zh) 2019-12-10
US20150316533A1 (en) 2015-11-05
JP2017519189A (ja) 2017-07-13
CN106605144A (zh) 2017-04-26
EP3137878A1 (en) 2017-03-08
US20220018765A1 (en) 2022-01-20
US11079325B2 (en) 2021-08-03
JP2019194622A (ja) 2019-11-07
WO2015167983A1 (en) 2015-11-05

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