CN106605144B - 用于通过光检测进行定点照护凝固测定的方法及系统 - Google Patents

用于通过光检测进行定点照护凝固测定的方法及系统 Download PDF

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Publication number
CN106605144B
CN106605144B CN201580034415.3A CN201580034415A CN106605144B CN 106605144 B CN106605144 B CN 106605144B CN 201580034415 A CN201580034415 A CN 201580034415A CN 106605144 B CN106605144 B CN 106605144B
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reaction chamber
optical
reference object
measurement system
light
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Chinese (zh)
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CN106605144A (zh
Inventor
约瑟夫·克里莫
曾寒松
罗恩·沙尔拉克
格特·布兰肯施泰因
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Werfen North America
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Instrumentation Laboratory Co
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/49—Blood
    • G01N33/4905—Determining clotting time of blood
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/49—Scattering, i.e. diffuse reflection within a body or fluid
    • G01N21/53—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke
    • G01N21/534—Scattering, i.e. diffuse reflection within a body or fluid within a flowing fluid, e.g. smoke by measuring transmission alone, i.e. determining opacity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/59—Transmissivity
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/062—LED's
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/063—Illuminating optical parts
    • G01N2201/0636—Reflectors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ecology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
CN201580034415.3A 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统 Active CN106605144B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201910870391.5A CN110554007A (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201461986475P 2014-04-30 2014-04-30
US61/986,475 2014-04-30
PCT/US2015/027715 WO2015167983A1 (en) 2014-04-30 2015-04-27 Methods and systems for point-of-care coagulation assays by optical detection

Related Child Applications (1)

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CN201910870391.5A Division CN110554007A (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

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CN106605144A CN106605144A (zh) 2017-04-26
CN106605144B true CN106605144B (zh) 2019-09-27

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CN201910870391.5A Pending CN110554007A (zh) 2014-04-30 2015-04-27 用于通过光检测进行定点照护凝固测定的方法及系统

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Country Status (7)

Country Link
US (2) US11079325B2 (enExample)
EP (1) EP3137878A1 (enExample)
JP (2) JP6567549B2 (enExample)
CN (2) CN106605144B (enExample)
AU (1) AU2015253478C1 (enExample)
CA (1) CA2946877C (enExample)
WO (1) WO2015167983A1 (enExample)

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BR112017004506B1 (pt) 2014-09-09 2023-12-19 Perosphere Technologies Inc Microchip de ensaio para a medição de coagulação em uma amostra de sangue ou plasma, dispositivo de microensaio para a medição de coagulação em uma amostra de sangue ou plasma de um indíviduo e método para medição de tempo de coagulação
WO2021195120A1 (en) * 2020-03-24 2021-09-30 In Diagnostics, Inc. Clinical spectrophotometer for general chemistry, immuno-assay and nucleic acid detection
US11906435B2 (en) 2020-09-11 2024-02-20 Atonarp Inc. System including auto-alignment
US12036344B2 (en) * 2020-11-13 2024-07-16 Fresenius Medical Care Holdings, Inc. Systems and methods for analyzing spent dialysate
CN115201498A (zh) * 2021-04-13 2022-10-18 基蛋生物科技股份有限公司 一种用于凝血检测的试剂卡及检测仪器

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EP2042610A1 (fr) 1999-02-23 2009-04-01 Asulab S.A. Système électrochimique pour la détermination d'un temps de coagulation du sang
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AU2003282351A1 (en) * 2002-11-12 2004-06-03 Inverness Medical Switzerland Gmbh Photometric determination of coagulation time in undiluted whole blood
DE10350880A1 (de) * 2003-10-31 2005-06-02 Roche Diagnostics Gmbh Verfahren zur Bestimmung eines Analyten mittels einer Extraktionsschicht
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WO2006115161A1 (ja) 2005-04-21 2006-11-02 Matsushita Electric Industrial Co., Ltd. 光ヘッド装置及び光情報装置
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JP5367509B2 (ja) 2009-08-27 2013-12-11 株式会社東芝 光検出装置、及びこの光検出装置を備える紙葉類処理装置
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Also Published As

Publication number Publication date
JP2019194622A (ja) 2019-11-07
JP2017519189A (ja) 2017-07-13
EP3137878A1 (en) 2017-03-08
CA2946877C (en) 2021-02-09
US20220018765A1 (en) 2022-01-20
US20150316533A1 (en) 2015-11-05
WO2015167983A1 (en) 2015-11-05
JP6567549B2 (ja) 2019-08-28
US11079325B2 (en) 2021-08-03
CA2946877A1 (en) 2015-11-05
CN110554007A (zh) 2019-12-10
AU2015253478C1 (en) 2019-01-17
US12571732B2 (en) 2026-03-10
CN106605144A (zh) 2017-04-26
AU2015253478A1 (en) 2016-11-17
AU2015253478B2 (en) 2018-04-26

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