JP6534650B2 - ロイコトリエンａ４加水分解酵素の阻害剤 - Google Patents

ロイコトリエンａ４加水分解酵素の阻害剤 Download PDF

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JP6534650B2
JP6534650B2 JP2016502433A JP2016502433A JP6534650B2 JP 6534650 B2 JP6534650 B2 JP 6534650B2 JP 2016502433 A JP2016502433 A JP 2016502433A JP 2016502433 A JP2016502433 A JP 2016502433A JP 6534650 B2 JP6534650 B2 JP 6534650B2
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optionally substituted
pharmaceutically acceptable
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JP2016513696A5 (enExample
JP2016513696A (ja
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ギルフォード，ウィリアム
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セルタクシス，インコーポレイテッド
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
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JP2016502433A 2013-03-14 2014-03-14 ロイコトリエンａ４加水分解酵素の阻害剤 Expired - Fee Related JP6534650B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361781193P 2013-03-14 2013-03-14
US61/781,193 2013-03-14
PCT/US2014/027428 WO2014152518A2 (en) 2013-03-14 2014-03-14 Inhibitors of leukotriene a4 hydrolase

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JP2016513696A JP2016513696A (ja) 2016-05-16
JP2016513696A5 JP2016513696A5 (enExample) 2017-04-13
JP6534650B2 true JP6534650B2 (ja) 2019-06-26

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US (2) US9777006B2 (enExample)
EP (1) EP2970309A4 (enExample)
JP (1) JP6534650B2 (enExample)
KR (1) KR20150127246A (enExample)
AU (1) AU2014239567B2 (enExample)
BR (1) BR112015022864A8 (enExample)
CA (1) CA2906084A1 (enExample)
MX (1) MX2015011678A (enExample)
RU (1) RU2678196C2 (enExample)
WO (1) WO2014152518A2 (enExample)

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KR20150127246A (ko) 2015-11-16
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US20180127424A1 (en) 2018-05-10
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US9777006B2 (en) 2017-10-03
US10399986B2 (en) 2019-09-03
US20160068534A1 (en) 2016-03-10
BR112015022864A8 (pt) 2019-11-26
BR112015022864A2 (pt) 2017-07-18
CA2906084A1 (en) 2014-09-25
MX2015011678A (es) 2016-07-08
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