JP6502337B2 - 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 - Google Patents
抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 Download PDFInfo
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- JP6502337B2 JP6502337B2 JP2016524371A JP2016524371A JP6502337B2 JP 6502337 B2 JP6502337 B2 JP 6502337B2 JP 2016524371 A JP2016524371 A JP 2016524371A JP 2016524371 A JP2016524371 A JP 2016524371A JP 6502337 B2 JP6502337 B2 JP 6502337B2
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Classifications
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- A61K31/13—Amines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Zoology (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Developing Agents For Electrophotography (AREA)
Applications Claiming Priority (5)
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| US201361842745P | 2013-07-03 | 2013-07-03 | |
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| US201461982611P | 2014-04-22 | 2014-04-22 | |
| US61/982,611 | 2014-04-22 | ||
| PCT/US2014/045389 WO2015003122A2 (en) | 2013-07-03 | 2014-07-03 | Regulation of glucose metabolism using anti-cgrp antibodies |
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| JP2019052046A Division JP2019112455A (ja) | 2013-07-03 | 2019-03-20 | 抗ｃｇｒｐ抗体を使用したグルコース代謝の調整 |
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| US10556945B2 (en) | 2014-03-21 | 2020-02-11 | Teva Pharmaceuticals International Gmbh | Antagonist antibodies directed against calcitonin gene-related peptide and methods using same |
| RS65360B1 (sr) | 2014-03-21 | 2024-04-30 | Teva Pharmaceuticals Int Gmbh | Antagonistička antitela specifična za peptid genski srodan kalcitoninu i postupci njihove upotrebe |
| US10588980B2 (en) | 2014-06-23 | 2020-03-17 | Novartis Ag | Fatty acids and their use in conjugation to biomolecules |
| AU2017331593B2 (en) | 2016-09-23 | 2022-04-28 | Teva Pharmaceuticals International Gmbh | Treating refractory migraine |
| SG10202003296VA (en) | 2020-04-06 | 2021-11-29 | H Lundbeck As | Treatment of most bothersome symptom (mbs) associated with migraine using anti-cgrp antibodies |
| WO2022040035A1 (en) * | 2020-08-15 | 2022-02-24 | Regeneron Pharmaceuticals, Inc. | Treatment of obesity in subjects having variant nucleic acid molecules encoding calcitonin receptor (calcr) |
| WO2023026245A1 (en) | 2021-08-27 | 2023-03-02 | H. Lundbeck A/S | Treatment of cluster headache using anti-cgrp antibodies |
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| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| GB8720115D0 (en) | 1987-08-26 | 1987-09-30 | Cooper G J S | Treatment of diabetes mellitus |
| GB8725529D0 (en) | 1987-10-30 | 1987-12-02 | Delta Biotechnology Ltd | Polypeptides |
| US5266561A (en) * | 1988-01-11 | 1993-11-30 | Amylin Pharmaceuticals, Inc. | Treatment of type 2 diabetes mellitus |
| EP0348490B1 (en) * | 1988-01-11 | 1995-09-27 | Amylin Pharmaceuticals, Inc. | Treatment of type 2 diabetes mellitus |
| US5364841A (en) * | 1988-01-11 | 1994-11-15 | Amylin Pharmaceuticals, Inc. | Treatment of obesity and essential hypertension and related disorders |
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| MX2016000220A (es) | 2016-08-18 |
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| EP3016684A4 (en) | 2017-06-07 |
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| NZ715834A (en) | 2021-11-26 |
| JP2016528198A (ja) | 2016-09-15 |
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| WO2015003122A3 (en) | 2015-03-19 |
| NZ754427A (en) | 2021-12-24 |
| JP2018168186A (ja) | 2018-11-01 |
| AU2019279945B2 (en) | 2022-01-20 |
| SG11201510618YA (en) | 2016-03-30 |
| ES2911690T3 (es) | 2022-05-20 |
| IL243355A0 (en) | 2016-03-31 |
| JP2019112455A (ja) | 2019-07-11 |
| TW202106335A (zh) | 2021-02-16 |
| CN105492026A (zh) | 2016-04-13 |
| US20150017166A1 (en) | 2015-01-15 |
| TW201536316A (zh) | 2015-10-01 |
| KR102476907B1 (ko) | 2022-12-13 |
| EP3016684A2 (en) | 2016-05-11 |
| AU2019279945A1 (en) | 2020-01-16 |
| IL243355B2 (en) | 2024-10-01 |
| CA2916980C (en) | 2023-02-21 |
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