JP6496662B2 - 磁気共鳴ガイドされた焦点式超音波を使用する加温療法処置のためのマルチ焦点超音波照射 - Google Patents
磁気共鳴ガイドされた焦点式超音波を使用する加温療法処置のためのマルチ焦点超音波照射 Download PDFInfo
- Publication number
- JP6496662B2 JP6496662B2 JP2015536248A JP2015536248A JP6496662B2 JP 6496662 B2 JP6496662 B2 JP 6496662B2 JP 2015536248 A JP2015536248 A JP 2015536248A JP 2015536248 A JP2015536248 A JP 2015536248A JP 6496662 B2 JP6496662 B2 JP 6496662B2
- Authority
- JP
- Japan
- Prior art keywords
- sound pressure
- target
- processor
- relative phase
- temperature
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
- A61B5/015—By temperature mapping of body part
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/055—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
- A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7278—Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/7475—User input or interface means, e.g. keyboard, pointing device, joystick
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B2017/00017—Electrical control of surgical instruments
- A61B2017/00022—Sensing or detecting at the treatment site
- A61B2017/00084—Temperature
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
- A61B2034/101—Computer-aided simulation of surgical operations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/36—Image-producing devices or illumination devices not otherwise provided for
- A61B90/37—Surgical systems with images on a monitor during operation
- A61B2090/374—NMR or MRI
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0078—Ultrasound therapy with multiple treatment transducers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N7/02—Localised ultrasound hyperthermia
- A61N2007/027—Localised ultrasound hyperthermia with multiple foci created simultaneously
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- High Energy & Nuclear Physics (AREA)
- Artificial Intelligence (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Physiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Signal Processing (AREA)
- Dermatology (AREA)
- Anesthesiology (AREA)
- Hematology (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261713132P | 2012-10-12 | 2012-10-12 | |
| US61/713,132 | 2012-10-12 | ||
| PCT/IB2013/059001 WO2014057388A1 (en) | 2012-10-12 | 2013-09-30 | Multi-foci sonications for hyperthermia treatments using magnetic resonance-guided focussed ultrasound. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015531290A JP2015531290A (ja) | 2015-11-02 |
| JP2015531290A5 JP2015531290A5 (enExample) | 2016-11-17 |
| JP6496662B2 true JP6496662B2 (ja) | 2019-04-03 |
Family
ID=49885310
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536248A Expired - Fee Related JP6496662B2 (ja) | 2012-10-12 | 2013-09-30 | 磁気共鳴ガイドされた焦点式超音波を使用する加温療法処置のためのマルチ焦点超音波照射 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150258353A1 (enExample) |
| EP (1) | EP2906291B1 (enExample) |
| JP (1) | JP6496662B2 (enExample) |
| CN (1) | CN104884127B (enExample) |
| BR (1) | BR112015007848A8 (enExample) |
| ES (1) | ES2732575T3 (enExample) |
| RU (1) | RU2650598C2 (enExample) |
| WO (1) | WO2014057388A1 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8444562B2 (en) | 2004-10-06 | 2013-05-21 | Guided Therapy Systems, Llc | System and method for treating muscle, tendon, ligament and cartilage tissue |
| US10864385B2 (en) | 2004-09-24 | 2020-12-15 | Guided Therapy Systems, Llc | Rejuvenating skin by heating tissue for cosmetic treatment of the face and body |
| US8535228B2 (en) | 2004-10-06 | 2013-09-17 | Guided Therapy Systems, Llc | Method and system for noninvasive face lifts and deep tissue tightening |
| US11883688B2 (en) | 2004-10-06 | 2024-01-30 | Guided Therapy Systems, Llc | Energy based fat reduction |
| US8133180B2 (en) | 2004-10-06 | 2012-03-13 | Guided Therapy Systems, L.L.C. | Method and system for treating cellulite |
| US20060111744A1 (en) | 2004-10-13 | 2006-05-25 | Guided Therapy Systems, L.L.C. | Method and system for treatment of sweat glands |
| US11235179B2 (en) | 2004-10-06 | 2022-02-01 | Guided Therapy Systems, Llc | Energy based skin gland treatment |
| EP2279697A3 (en) | 2004-10-06 | 2014-02-19 | Guided Therapy Systems, L.L.C. | Method and system for non-invasive cosmetic enhancement of blood vessel disorders |
| US8690779B2 (en) | 2004-10-06 | 2014-04-08 | Guided Therapy Systems, Llc | Noninvasive aesthetic treatment for tightening tissue |
| KR20200021102A (ko) | 2004-10-06 | 2020-02-27 | 가이디드 테라피 시스템스, 엘.엘.씨. | 초음파 치료 시스템 |
| US9827449B2 (en) | 2004-10-06 | 2017-11-28 | Guided Therapy Systems, L.L.C. | Systems for treating skin laxity |
| US9694212B2 (en) | 2004-10-06 | 2017-07-04 | Guided Therapy Systems, Llc | Method and system for ultrasound treatment of skin |
| US11724133B2 (en) | 2004-10-07 | 2023-08-15 | Guided Therapy Systems, Llc | Ultrasound probe for treatment of skin |
| US11207548B2 (en) | 2004-10-07 | 2021-12-28 | Guided Therapy Systems, L.L.C. | Ultrasound probe for treating skin laxity |
| US12102473B2 (en) | 2008-06-06 | 2024-10-01 | Ulthera, Inc. | Systems for ultrasound treatment |
| KR102087909B1 (ko) | 2008-06-06 | 2020-03-12 | 얼테라, 인크 | 코스메틱 치료 시스템 |
| WO2010075547A2 (en) | 2008-12-24 | 2010-07-01 | Guided Therapy Systems, Llc | Methods and systems for fat reduction and/or cellulite treatment |
| US9510802B2 (en) | 2012-09-21 | 2016-12-06 | Guided Therapy Systems, Llc | Reflective ultrasound technology for dermatological treatments |
| WO2014118632A1 (en) * | 2013-01-29 | 2014-08-07 | Insightec, Ltd. | Simulation-based focused-ultrasound treatment planning |
| US11376074B2 (en) | 2013-01-25 | 2022-07-05 | Yoav Levy | Simulation-based focused-ultrasound treatment planning |
| CN204017181U (zh) | 2013-03-08 | 2014-12-17 | 奥赛拉公司 | 美学成像与处理系统、多焦点处理系统和执行美容过程的系统 |
| KR102465947B1 (ko) | 2014-04-18 | 2022-11-10 | 얼테라, 인크 | 밴드 트랜스듀서 초음파 치료 |
| JP2016019586A (ja) * | 2014-07-14 | 2016-02-04 | 株式会社日立メディコ | 凍結治療システム |
| CN107073291B (zh) * | 2014-10-17 | 2021-01-05 | 皇家飞利浦有限公司 | 用于超声热疗和成像的超声片块 |
| RU2720661C2 (ru) | 2016-01-18 | 2020-05-12 | Ультера, Инк. | Компактное ультразвуковое устройство, содержащее кольцеобразную ультразвуковую матрицу, электрически соединенную по периферии с гибкой печатной платой, и способ сборки такого устройства |
| KR20230149878A (ko) | 2016-08-16 | 2023-10-27 | 얼테라, 인크 | 이미징 오정렬을 감소시키도록 구성된 초음파 이미징 시스템, 초음파 이미징 모듈 및 이미징 오정렬을 감소시키는 방법 |
| JP7289061B2 (ja) * | 2017-06-29 | 2023-06-09 | インサイテック リミテッド | シミュレーションベースの薬物処置計画 |
| EP3459596A1 (en) | 2017-09-26 | 2019-03-27 | Koninklijke Philips N.V. | Power adjustment in magnetic resonance guided high intensity focused ultrasound |
| CN111225609B (zh) * | 2017-10-19 | 2024-02-02 | 博放医疗有限公司 | 用于热疗法的处理系统和动态校正方法 |
| US11191444B2 (en) | 2017-10-19 | 2021-12-07 | Profound Medical Inc. | Processing system and dynamic correction method for thermal therapy |
| JP7502185B2 (ja) * | 2017-12-11 | 2024-06-18 | インサイテック リミテッド | 適応閉ループ超音波療法 |
| TW202529848A (zh) | 2018-01-26 | 2025-08-01 | 美商奧賽拉公司 | 用於多個維度中的同時多聚焦超音治療的系統和方法 |
| WO2019164836A1 (en) | 2018-02-20 | 2019-08-29 | Ulthera, Inc. | Systems and methods for combined cosmetic treatment of cellulite with ultrasound |
| US11684807B2 (en) * | 2018-12-27 | 2023-06-27 | Insightec Ltd. | Optimization of transducer configurations in ultrasound procedures |
| CA3137928A1 (en) | 2019-07-15 | 2021-01-21 | Ulthera, Inc. | Systems and methods for measuring elasticity with imaging of ultrasound multi-focus shearwaves in multiple dimensions |
| ES2793798B2 (es) * | 2020-02-13 | 2022-04-29 | Julia Jose Manuel Saenz | Aparato emisor de ultrasonidos para aplicacion de tratamientos selectivos sobre tejido adiposo en procesos de remodelacion / rejuvenecimiento corporal |
| CN111494817B (zh) * | 2020-02-26 | 2022-03-04 | 南北兄弟药业投资有限公司 | 一种hifu设备大焦域形成系统及其焦域形成方法 |
| CN111529974B (zh) * | 2020-06-01 | 2021-09-24 | 南京大学 | 一种基于环形阵列的超声定向定温加热方法 |
| US20220252550A1 (en) * | 2021-01-26 | 2022-08-11 | Ultraleap Limited | Ultrasound Acoustic Field Manipulation Techniques |
| CN112704822B (zh) * | 2021-02-07 | 2022-05-31 | 河南省中医院(河南中医药大学第二附属医院) | 一种用于妇科的超声热疗设备 |
| CN113133826B (zh) * | 2021-04-23 | 2023-04-07 | 四川大学华西医院 | 一种hifu低温聚焦方法、设备和系统 |
| NO20221061A1 (en) * | 2022-10-05 | 2024-04-08 | Exact Therapeutics As | Act enhanced ablation therapy |
| CN117018483B (zh) * | 2023-10-08 | 2023-12-22 | 北京小超科技有限公司 | 一种温度增强的微分多焦点超声空化装置 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4893624A (en) * | 1988-06-21 | 1990-01-16 | Massachusetts Institute Of Technology | Diffuse focus ultrasound hyperthermia system |
| JP3386488B2 (ja) * | 1992-03-10 | 2003-03-17 | 株式会社東芝 | 超音波治療装置 |
| JPH1014967A (ja) * | 1996-06-30 | 1998-01-20 | Shimadzu Corp | 超音波ハイパーサーミア装置 |
| CN1058905C (zh) * | 1998-01-25 | 2000-11-29 | 重庆海扶(Hifu)技术有限公司 | 高强度聚焦超声肿瘤扫描治疗系统 |
| JP4460691B2 (ja) * | 1998-09-30 | 2010-05-12 | 株式会社東芝 | 超音波治療装置 |
| FR2823678B1 (fr) * | 2001-04-20 | 2004-01-09 | Centre Nat Rech Scient | Ensemble de traitement thermique de tissus biologiques |
| JP4088126B2 (ja) * | 2002-09-09 | 2008-05-21 | 株式会社東芝 | 超音波治療装置 |
| US20100030076A1 (en) * | 2006-08-01 | 2010-02-04 | Kobi Vortman | Systems and Methods for Simultaneously Treating Multiple Target Sites |
| BRPI0914520A2 (pt) * | 2008-11-04 | 2015-12-15 | Koninkl Philips Electronics Nv | meio de armazenamento legível em computador, e, sistema de ablação por ultrassom |
| WO2010122449A1 (en) * | 2009-04-20 | 2010-10-28 | Koninklijke Philips Electronics N.V. | A control apparatus for controlling a therapeutic apparatus |
| EP3406299B1 (en) * | 2010-06-09 | 2021-08-04 | Regents of the University of Minnesota | Dual mode ultrasound transducer (dmut) system for controlling delivery of ultrasound therapy |
| US20120191020A1 (en) * | 2011-01-25 | 2012-07-26 | Shuki Vitek | Uniform thermal treatment of tissue interfaces |
-
2013
- 2013-09-30 RU RU2015117609A patent/RU2650598C2/ru not_active IP Right Cessation
- 2013-09-30 CN CN201380053265.1A patent/CN104884127B/zh not_active Expired - Fee Related
- 2013-09-30 WO PCT/IB2013/059001 patent/WO2014057388A1/en not_active Ceased
- 2013-09-30 JP JP2015536248A patent/JP6496662B2/ja not_active Expired - Fee Related
- 2013-09-30 EP EP13814610.5A patent/EP2906291B1/en not_active Not-in-force
- 2013-09-30 ES ES13814610T patent/ES2732575T3/es active Active
- 2013-09-30 US US14/433,468 patent/US20150258353A1/en not_active Abandoned
- 2013-09-30 BR BR112015007848A patent/BR112015007848A8/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| BR112015007848A8 (pt) | 2018-02-06 |
| WO2014057388A1 (en) | 2014-04-17 |
| CN104884127A (zh) | 2015-09-02 |
| EP2906291A1 (en) | 2015-08-19 |
| ES2732575T3 (es) | 2019-11-25 |
| RU2650598C2 (ru) | 2018-04-16 |
| EP2906291B1 (en) | 2019-05-15 |
| JP2015531290A (ja) | 2015-11-02 |
| CN104884127B (zh) | 2018-11-02 |
| BR112015007848A2 (pt) | 2017-08-08 |
| US20150258353A1 (en) | 2015-09-17 |
| RU2015117609A (ru) | 2016-12-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6496662B2 (ja) | 磁気共鳴ガイドされた焦点式超音波を使用する加温療法処置のためのマルチ焦点超音波照射 | |
| CN101888876B (zh) | 运动补偿的影像引导聚焦超声治疗系统 | |
| CA2849106C (en) | System and method for control and monitoring of conformal thermal therapy | |
| Diederich et al. | Ultrasound technology for hyperthermia | |
| US10694974B2 (en) | Method and system for MRI-based targeting, monitoring, and quantification of thermal and mechanical bioeffects in tissue induced by high intensity focused ultrasound | |
| Partanen et al. | Reduction of peak acoustic pressure and shaping of heated region by use of multifoci sonications in MR‐guided high‐intensity focused ultrasound mediated mild hyperthermia | |
| JP2022541604A (ja) | 超音波療法の間の動的に変化する媒体のための収差補正 | |
| JPH07184907A (ja) | 超音波治療装置 | |
| Guillemin et al. | Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature | |
| Zhou | Generation of uniform lesions in high intensity focused ultrasound ablation | |
| JP2023549792A (ja) | 超音波手技のためのマルチパラメトリック最適化 | |
| Ellens et al. | Frequency considerations for deep ablation with high‐intensity focused ultrasound: a simulation study | |
| Sasaki et al. | Effect of split-focus approach on producing larger coagulation in swine liver | |
| Aslani et al. | A fully electronically steerable therapeutic ultrasound phased array with MR-guidance | |
| Qian et al. | Uniform tissue lesion formation induced by high-intensity focused ultrasound along a spiral pathway | |
| Pichardo et al. | New design for an endoesophageal sector-based array for the treatment of atrial fibrillation: a parametric simulation study | |
| Fan et al. | Comparative study of lesions created by high-intensity focused ultrasound using sequential discrete and continuous scanning strategies | |
| Burtnyk et al. | 3D conformal MRI-controlled transurethral ultrasound prostate therapy: validation of numerical simulations and demonstration in tissue-mimicking gel phantoms | |
| Ji et al. | A method of introducing cooling time between multiple sonications in focused ultrasound surgery | |
| Bouchoux et al. | Interstitial thermal ablation with a fast rotating dual-mode transducer | |
| Staruch et al. | MRI-controlled ultrasound thermal therapy | |
| Luo et al. | Treatment planning of scanning time and path for phased high-intensity focused ultrasound surgery | |
| N'Djin et al. | Dual-frequency ultrasound focal therapy for MRI-guided transurethral treatment of the prostate: study in gel phantom | |
| Lin et al. | P2G-2 High intensity focused ultrasound thermal therapy for liver tumor with respiration motion | |
| Cai et al. | Treatment Planning of Ultrasound Intensity and Heating Time for Phased HIFU Surgery |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150608 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20160929 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20160929 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20170622 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20170707 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20170929 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20170929 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20171227 |
|
| A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20180105 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180507 |
|
| A711 | Notification of change in applicant |
Free format text: JAPANESE INTERMEDIATE CODE: A711 Effective date: 20180508 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A821 Effective date: 20180509 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20190205 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20190206 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190219 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190311 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6496662 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| LAPS | Cancellation because of no payment of annual fees |