ES2732575T3 - Sonicaciones de multifoco para tratamientos de hipertermia que usan ultrasonidos enfocados guiados por resonancia magnética - Google Patents

Sonicaciones de multifoco para tratamientos de hipertermia que usan ultrasonidos enfocados guiados por resonancia magnética Download PDF

Info

Publication number
ES2732575T3
ES2732575T3 ES13814610T ES13814610T ES2732575T3 ES 2732575 T3 ES2732575 T3 ES 2732575T3 ES 13814610 T ES13814610 T ES 13814610T ES 13814610 T ES13814610 T ES 13814610T ES 2732575 T3 ES2732575 T3 ES 2732575T3
Authority
ES
Spain
Prior art keywords
sonication
temperature
multifoco
target
processors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES13814610T
Other languages
English (en)
Spanish (es)
Inventor
Ari Ilkka Mikael Partanen
Matti Oskari Tillander
Matthew Dreher
Max Köhler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Profound Medical Inc
United States Department of Health and Human Services
Original Assignee
Profound Medical Inc
United States Department of Health and Human Services
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Profound Medical Inc, United States Department of Health and Human Services filed Critical Profound Medical Inc
Application granted granted Critical
Publication of ES2732575T3 publication Critical patent/ES2732575T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A61B5/015—By temperature mapping of body part
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839—Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7271—Specific aspects of physiological measurement analysis
    • A61B5/7278—Artificial waveform generation or derivation, e.g. synthesizing signals from measured signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/7475—User input or interface means, e.g. keyboard, pointing device, joystick
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00017—Electrical control of surgical instruments
    • A61B2017/00022—Sensing or detecting at the treatment site
    • A61B2017/00084—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101—Computer-aided simulation of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/36—Image-producing devices or illumination devices not otherwise provided for
    • A61B90/37—Surgical systems with images on a monitor during operation
    • A61B2090/374—NMR or MRI
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2576/00—Medical imaging apparatus involving image processing or analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N2007/0078—Ultrasound therapy with multiple treatment transducers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A61N2007/027—Localised ultrasound hyperthermia with multiple foci created simultaneously

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Artificial Intelligence (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Signal Processing (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Surgical Instruments (AREA)
  • High Energy & Nuclear Physics (AREA)
ES13814610T 2012-10-12 2013-09-30 Sonicaciones de multifoco para tratamientos de hipertermia que usan ultrasonidos enfocados guiados por resonancia magnética Active ES2732575T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261713132P 2012-10-12 2012-10-12
PCT/IB2013/059001 WO2014057388A1 (en) 2012-10-12 2013-09-30 Multi-foci sonications for hyperthermia treatments using magnetic resonance-guided focussed ultrasound.

Publications (1)

Publication Number Publication Date
ES2732575T3 true ES2732575T3 (es) 2019-11-25

Family

ID=49885310

Family Applications (1)

Application Number Title Priority Date Filing Date
ES13814610T Active ES2732575T3 (es) 2012-10-12 2013-09-30 Sonicaciones de multifoco para tratamientos de hipertermia que usan ultrasonidos enfocados guiados por resonancia magnética

Country Status (8)

Country Link
US (1) US20150258353A1 (enExample)
EP (1) EP2906291B1 (enExample)
JP (1) JP6496662B2 (enExample)
CN (1) CN104884127B (enExample)
BR (1) BR112015007848A8 (enExample)
ES (1) ES2732575T3 (enExample)
RU (1) RU2650598C2 (enExample)
WO (1) WO2014057388A1 (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10864385B2 (en) 2004-09-24 2020-12-15 Guided Therapy Systems, Llc Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US20060122508A1 (en) 2004-10-06 2006-06-08 Guided Therapy Systems, L.L.C. Method and system for noninvasive face lifts and deep tissue tightening
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US11235179B2 (en) 2004-10-06 2022-02-01 Guided Therapy Systems, Llc Energy based skin gland treatment
EP2279698A3 (en) 2004-10-06 2014-02-19 Guided Therapy Systems, L.L.C. Method and system for non-invasive cosmetic enhancement of stretch marks
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
US8690778B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Energy-based tissue tightening
US11883688B2 (en) 2004-10-06 2024-01-30 Guided Therapy Systems, Llc Energy based fat reduction
US11724133B2 (en) 2004-10-07 2023-08-15 Guided Therapy Systems, Llc Ultrasound probe for treatment of skin
US11207548B2 (en) 2004-10-07 2021-12-28 Guided Therapy Systems, L.L.C. Ultrasound probe for treating skin laxity
KR102479936B1 (ko) 2008-06-06 2022-12-22 얼테라, 인크 초음파 치료 시스템
US12102473B2 (en) 2008-06-06 2024-10-01 Ulthera, Inc. Systems for ultrasound treatment
CA2748362A1 (en) 2008-12-24 2010-07-01 Michael H. Slayton Methods and systems for fat reduction and/or cellulite treatment
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
US11376074B2 (en) 2013-01-25 2022-07-05 Yoav Levy Simulation-based focused-ultrasound treatment planning
EP2950737B1 (en) * 2013-01-29 2023-01-11 Insightec Ltd. Simulation-based focused-ultrasound treatment planning
CN204637350U (zh) 2013-03-08 2015-09-16 奥赛拉公司 美学成像与处理系统、多焦点处理系统和执行美容过程的系统
US20170028227A1 (en) 2014-04-18 2017-02-02 Ulthera, Inc. Band transducer ultrasound therapy
JP2016019586A (ja) * 2014-07-14 2016-02-04 株式会社日立メディコ 凍結治療システム
WO2016058963A1 (en) * 2014-10-17 2016-04-21 Koninklijke Philips N.V. An ultrasound patch for ultrasound hyperthermia and imaging
PT3405294T (pt) 2016-01-18 2023-03-03 Ulthera Inc Dispositivo de ultrassom compacto com matriz anular de ultrassom ligada eletricamente de modo periférico a placa de circuito impresso flexível
CN109562279B (zh) 2016-08-16 2022-03-15 奥赛拉公司 用于皮肤的美容超声治疗的系统和方法
CN111032157B (zh) * 2017-06-29 2023-04-21 医视特有限公司 基于模拟的药物治疗计划
EP3459596A1 (en) 2017-09-26 2019-03-27 Koninklijke Philips N.V. Power adjustment in magnetic resonance guided high intensity focused ultrasound
JP2021500126A (ja) * 2017-10-19 2021-01-07 プロファウンド メディカル インク 熱治療のための処理システムおよびダイナミック補正方法
US11191444B2 (en) 2017-10-19 2021-12-07 Profound Medical Inc. Processing system and dynamic correction method for thermal therapy
EP3723857A1 (en) * 2017-12-11 2020-10-21 Insightec Ltd. Adaptive, closed- loop ultrasound therapy
TW202529848A (zh) 2018-01-26 2025-08-01 美商奧賽拉公司 用於多個維度中的同時多聚焦超音治療的系統和方法
WO2019164836A1 (en) 2018-02-20 2019-08-29 Ulthera, Inc. Systems and methods for combined cosmetic treatment of cellulite with ultrasound
CA3116332A1 (en) 2018-11-30 2020-06-04 Ulthera, Inc. Systems and methods for enhancing efficacy of ultrasound treatment
US11684807B2 (en) 2018-12-27 2023-06-27 Insightec Ltd. Optimization of transducer configurations in ultrasound procedures
TWI864044B (zh) 2019-07-15 2024-12-01 美商奧賽拉公司 用於利用多維度的超音波多焦點剪切波的成像來測量彈性的系統和方法
AU2020371044B2 (en) 2019-10-25 2025-10-30 Exact Therapeutics As Treatment of pancreatic cancer
ES2793798B2 (es) * 2020-02-13 2022-04-29 Julia Jose Manuel Saenz Aparato emisor de ultrasonidos para aplicacion de tratamientos selectivos sobre tejido adiposo en procesos de remodelacion / rejuvenecimiento corporal
CN111494817B (zh) * 2020-02-26 2022-03-04 南北兄弟药业投资有限公司 一种hifu设备大焦域形成系统及其焦域形成方法
CN111529974B (zh) * 2020-06-01 2021-09-24 南京大学 一种基于环形阵列的超声定向定温加热方法
US20220252550A1 (en) * 2021-01-26 2022-08-11 Ultraleap Limited Ultrasound Acoustic Field Manipulation Techniques
CN112704822B (zh) * 2021-02-07 2022-05-31 河南省中医院(河南中医药大学第二附属医院) 一种用于妇科的超声热疗设备
CN113133826B (zh) * 2021-04-23 2023-04-07 四川大学华西医院 一种hifu低温聚焦方法、设备和系统
NO20221061A1 (en) * 2022-10-05 2024-04-08 Exact Therapeutics As Act enhanced ablation therapy
CN117018483B (zh) * 2023-10-08 2023-12-22 北京小超科技有限公司 一种温度增强的微分多焦点超声空化装置

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4893624A (en) * 1988-06-21 1990-01-16 Massachusetts Institute Of Technology Diffuse focus ultrasound hyperthermia system
JP3386488B2 (ja) * 1992-03-10 2003-03-17 株式会社東芝 超音波治療装置
JPH1014967A (ja) * 1996-06-30 1998-01-20 Shimadzu Corp 超音波ハイパーサーミア装置
CN1058905C (zh) * 1998-01-25 2000-11-29 重庆海扶(Hifu)技术有限公司 高强度聚焦超声肿瘤扫描治疗系统
JP4460691B2 (ja) * 1998-09-30 2010-05-12 株式会社東芝 超音波治療装置
FR2823678B1 (fr) * 2001-04-20 2004-01-09 Centre Nat Rech Scient Ensemble de traitement thermique de tissus biologiques
JP4088126B2 (ja) * 2002-09-09 2008-05-21 株式会社東芝 超音波治療装置
US20100030076A1 (en) * 2006-08-01 2010-02-04 Kobi Vortman Systems and Methods for Simultaneously Treating Multiple Target Sites
BRPI0914520A2 (pt) * 2008-11-04 2015-12-15 Koninkl Philips Electronics Nv meio de armazenamento legível em computador, e, sistema de ablação por ultrassom
US20120035464A1 (en) * 2009-04-20 2012-02-09 Koninklijke Philips Electronics N.V. Control apparatus for controlling a therapeutic apparatus
US10231712B2 (en) * 2010-06-09 2019-03-19 Regents Of The University Of Minnesota Dual mode ultrasound transducer (DMUT) system and method for controlling delivery of ultrasound therapy
US20120191020A1 (en) * 2011-01-25 2012-07-26 Shuki Vitek Uniform thermal treatment of tissue interfaces

Also Published As

Publication number Publication date
JP2015531290A (ja) 2015-11-02
EP2906291B1 (en) 2019-05-15
EP2906291A1 (en) 2015-08-19
US20150258353A1 (en) 2015-09-17
RU2650598C2 (ru) 2018-04-16
BR112015007848A8 (pt) 2018-02-06
CN104884127B (zh) 2018-11-02
JP6496662B2 (ja) 2019-04-03
WO2014057388A1 (en) 2014-04-17
CN104884127A (zh) 2015-09-02
BR112015007848A2 (pt) 2017-08-08
RU2015117609A (ru) 2016-12-10

Similar Documents

Publication Publication Date Title
EP2906291B1 (en) Multi-foci sonications for hyperthermia treatments using magnetic resonance-guided focussed ultrasound
Bobkova et al. Focusing of high-intensity ultrasound through the rib cage using a therapeutic random phased array
Partanen et al. Mild hyperthermia with magnetic resonance-guided high-intensity focused ultrasound for applications in drug delivery
Pernot et al. In vivo transcranial brain surgery with an ultrasonic time reversal mirror
Kyriakou et al. Full-wave acoustic and thermal modeling of transcranial ultrasound propagation and investigation of skull-induced aberration correction techniques: a feasibility study
Partanen et al. Reduction of peak acoustic pressure and shaping of heated region by use of multifoci sonications in MR‐guided high‐intensity focused ultrasound mediated mild hyperthermia
US20120191020A1 (en) Uniform thermal treatment of tissue interfaces
JP2022541604A (ja) 超音波療法の間の動的に変化する媒体のための収差補正
Ellens et al. A novel, flat, electronically-steered phased array transducer for tissue ablation: preliminary results
Guillemin et al. Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature
Hutchinson et al. Intracavitary ultrasound phased arrays for noninvasive prostate surgery
JP2023549792A (ja) 超音波手技のためのマルチパラメトリック最適化
Liu et al. Development of a spherically focused phased array transducer for ultrasonic image-guided hyperthermia
Zhou Generation of uniform lesions in high intensity focused ultrasound ablation
Ding et al. Modulation of transcranial focusing thermal deposition in nonlinear HIFU brain surgery by numerical simulation
Salgaonkar et al. Model‐based feasibility assessment and evaluation of prostate hyperthermia with a commercial MR‐guided endorectal HIFU ablation array
Ellens et al. Frequency considerations for deep ablation with high‐intensity focused ultrasound: a simulation study
Canney et al. A multi-element interstitial ultrasound applicator for the thermal therapy of brain tumors
Filippou et al. Experimental evaluation of the near-field and far-field heating of focused ultrasound using the thermal dose concept
Sasaki et al. Effect of split-focus approach on producing larger coagulation in swine liver
Dera et al. Experimental evaluation of targeting accuracy of ultrasound imaging-guided robotic HIFU ablative system for the treatment of solid tumors in pre-clinical studies
Chopra et al. Feasibility of linear arrays for interstitial ultrasound thermal therapy
Wang et al. Optimization of pulsed focused ultrasound exposures for hyperthermia applications
Wang et al. Extracorporeal, low-energy focused ultrasound for noninvasive and nondestructive targeted hyperthermia
Sun et al. Adaptive real‐time closed‐loop temperature control for ultrasound hyperthermia using magnetic resonance thermometry