JP6449189B2 - 睡眠呼吸障害の治療方法 - Google Patents
睡眠呼吸障害の治療方法 Download PDFInfo
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- JP6449189B2 JP6449189B2 JP2016060573A JP2016060573A JP6449189B2 JP 6449189 B2 JP6449189 B2 JP 6449189B2 JP 2016060573 A JP2016060573 A JP 2016060573A JP 2016060573 A JP2016060573 A JP 2016060573A JP 6449189 B2 JP6449189 B2 JP 6449189B2
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Description
Claims (15)
- 睡眠呼吸障害取扱システムであって、
生理学的状態を検出するように構成された検出モジュールと、
気道開存性関連筋肉を刺激する第1神経に神経刺激信号を選択的に印加するように構成された植込み可能なパルス発生器(IPG)と、
を備え、
前記植込み可能なパルス発生器(IPG)は、特定の患者について前記システムを較正するように構成された較正機能を含み、
前記較正機能は、前記較正を実行するために、
前記生理学的状態から前記検出モジュールを介してIPGベースの生理学的パラメータを追跡し、
独立に、及び、同時に実行された睡眠ポリグラフ検査について、追跡されたIPGベースの各生理学的パラメータのIPGベースのどの生理学的パラメータが、前記特定の患者について睡眠呼吸障害行動を示すかを識別する、
ように構成されている、システム。 - 前記植込み可能なパルス発生器は、追跡され、識別されたIPGベースの生理学的パラメータに基づいて、自動的に調整可能な処置処方を決定し、睡眠呼吸障害行動に応じた前記処置処方を介して前記神経刺激信号を選択的に印加する、ように構成されている、請求項1に記載のシステム。
- 睡眠呼吸障害取扱システムであって、
生理学的状態を検出するように構成された検出モジュールと、
気道開存性関連筋肉を刺激する第1神経に神経刺激信号を選択的に印加するように構成された植込み可能なパルス発生器と、
を備え、
前記植込み可能なパルス発生器は、特定の患者について前記システムを較正するように構成された較正機能を含み、
前記較正機能は、前記較正を実行するために、
前記生理学的状態から前記検出モジュールを介してIPGベースの生理学的パラメータを追跡し、
追跡された各生理学的パラメータ、又は、そのような生理学的パラメータの組み合わせのどの生理学的パラメータが、前記特定の患者について睡眠呼吸障害行動を示すかを識別する、
ように構成されていると共に、
前記較正機能は、
睡眠呼吸障害行動取扱システムと独立して実行可能な睡眠ポリグラフ計(PSG)に関連する複数の追跡可能な睡眠検査パラメータを規定し、少なくとも一つの前記追跡可能なPSGベースの各睡眠検査パラメータは、少なくとも一つの外的に測定されたパラメータを含み、
少なくとも一つの内的に測定されたパラメータを含めるように追跡可能なIPGベースの前記各生理学的パラメータを規定し、
特定の患者の睡眠呼吸障害行動に基づいて、前記追跡可能なIPGベースの生理学的パラメータの前記少なくとも一つの内的に測定されたパラメータの、前記追跡可能なPSGベースの睡眠検査パラメータの前記少なくとも一つの外的に測定されたパラメータに関する関係を見積もる、
ように構成されている、システム。 - 前記較正機能は、内的に測定された呼吸パラメータを含めるように前記追跡可能なIPGベースの生理学的パラメータの前記少なくとも一つの内的に測定されたパラメータを規定するように構成されている、請求項3に記載のシステム。
- 前記少なくとも一つの内的に測定された呼吸パラメータは、呼吸圧力と生体インピーダンスの少なくとも一つを含む、請求項4に記載のシステム。
- 前記少なくとも一つの内的に測定されたパラメータは、身体位置パラメータを含む、請求項5に記載のシステム。
- 前記検出モジュールは、前記内的に測定された呼吸パラメータ及び身体位置パラメータの少なくとも一つを検出する加速度計を含む、請求項6に記載のシステム。
- 前記較正機能は、内的に測定された心拍パラメータを含めるように追跡可能な前記IPGベースの各生理学的パラメータの前記少なくとも一つの内的に測定されたパラメータを規定するように構成されている、請求項3に記載のシステム。
- 前記較正機能は、口−鼻孔気流睡眠パラメータを含めるように前記追跡可能なPSGベースの睡眠検査パラメータの前記少なくとも一つの外的に測定されたパラメータを規定するように構成されている、請求項3に記載のシステム。
- 前記植込み可能なパルス発生器は、前記較正機能を内蔵する自動治療マネージャを含み、前記較正機能は、
前記検出モジュール及び前記植込み可能なパルス発生器を介して、前記追跡可能なIPGベースの生理学的パラメータの前記少なくとも一つの内的に測定されたパラメータを含む、内的に検出された身体位置パラメータによる身体位置のパターンを識別し、
前記識別したパターンを用いて、前記追跡可能なIPGベースの生理学的パラメータの前記少なくとも一つの内的に測定されたパラメータの、前記追跡可能なPSGベースの睡眠検査パラメータの前記少なくとも一つの外的に測定したパラメータに関する関係を満足する、
ように構成されている、請求項3に記載のシステム。 - 前記較正機能は、
前記独立に実行可能な睡眠ポリグラフ計を介して、外的に観察した睡眠呼吸障害行動を示す身体位置のパターンを識別し、前記外的に観察した身体位置のパターンは、前記追跡可能なPSGベースの睡眠検査パラメータの前記少なくとも一つの外的に測定されたパラメータを含み、
外的に観察し、識別した身体位置の前記パターンに関して、内的に検出した前記身体位置パラメータの識別した前記パターンを較正し、
内的に検出され、較正した前記身体位置パラメータを用いて、位置を検出し、前記追跡されたIPGベースの生理学的パラメータの前記少なくとも一つの内的に測定したパラメータの、前記追跡されたPSGベースの睡眠検査パラメータの前記少なくとも一つの外的に測定したパラメータに関する関係を満足する、
ように構成されている、請求項10に記載のシステム。 - 睡眠呼吸障害取扱システムであって、
生理学的状態を検出するように構成された検出モジュールと、
気道開存性関連筋肉を刺激する第1神経に神経刺激信号を選択的に印加するように構成された植込み可能なパルス発生器(IPG)と、
を備え、
前記植込み可能なパルス発生器(IPG)は、特定の患者について前記システムを較正するように構成された較正機能を含み、
前記較正機能は、前記較正を実行するために、
前記生理学的状態から前記検出モジュールを介してIPGベースの生理学的パラメータを追跡し、
追跡された各生理学的パラメータのどの生理学的パラメータが、前記特定の患者について睡眠呼吸障害行動を示すかを識別し、
IPGベースの生理学的パラメータを追跡している間に前記睡眠呼吸障害取扱システムと独立に実行された睡眠ポリグラフ計(PSG)検査から睡眠検査パラメータを受け付け、
追跡された睡眠検査パラメータから睡眠呼吸障害行動のパターンを識別し、追跡された睡眠検査パラメータの各パラメータのどのパラメータが前記患者についての睡眠呼吸障害行動を示すかを識別し、
追跡されたIPGベースのどの生理学的パラメータが、前記特定の患者の睡眠呼吸障害行動を示すのかを識別するように、前記追跡されたIPGベースの各生理学的パラメータの前記PSGベースの各生理学的パラメータに関する関係を見積もる、
ように構成されている、システム。 - 睡眠呼吸障害行動の前記識別されたパターンが、
睡眠呼吸障害行動の睡眠量パターンと、
睡眠呼吸障害行動の身体位置パターンと、
の少なくとも1つと相関する程度を決定することを含む、請求項12に記載のシステム。 - 睡眠呼吸障害行動の前記識別されたパターンが、
睡眠呼吸障害行動の時間パターンと、
睡眠呼吸障害行動の夜間の曜日パターンと、
睡眠呼吸障害行動の睡眠段階パターンと、
睡眠呼吸障害行動の心拍パターンと、
の少なくとも1つと相関する程度を決定することを含む、請求項13に記載のシステム。 - 前記一つの外的に測定されたパラメータは、血中酸素飽和度パラメータを含む、請求項3に記載のシステム。
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US20200146620A9 (en) | 2020-05-14 |
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JP2019055255A (ja) | 2019-04-11 |
JP5575789B2 (ja) | 2014-08-20 |
US20110264164A1 (en) | 2011-10-27 |
EP3184045B1 (en) | 2023-12-06 |
JP2021104387A (ja) | 2021-07-26 |
US20220160295A1 (en) | 2022-05-26 |
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