JP6411215B2 - 虚血傷害を治療するためのシステアミンおよび／またはシスタミン - Google Patents

虚血傷害を治療するためのシステアミンおよび／またはシスタミン Download PDF

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Publication number
JP6411215B2
JP6411215B2 JP2014542590A JP2014542590A JP6411215B2 JP 6411215 B2 JP6411215 B2 JP 6411215B2 JP 2014542590 A JP2014542590 A JP 2014542590A JP 2014542590 A JP2014542590 A JP 2014542590A JP 6411215 B2 JP6411215 B2 JP 6411215B2
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JP
Japan
Prior art keywords
cysteamine
adiponectin
subject
cystamine
pharmaceutically acceptable
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Expired - Fee Related
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JP2014542590A
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English (en)
Japanese (ja)
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JP2014533701A (ja
JP2014533701A5 (OSRAM
Inventor
ドヒル，ランジャン
フィリップス，スーザン，エー．
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University of California
University of California Berkeley
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University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014542590A 2011-11-22 2012-11-21 虚血傷害を治療するためのシステアミンおよび／またはシスタミン Expired - Fee Related JP6411215B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161563034P 2011-11-22 2011-11-22
US61/563,034 2011-11-22
PCT/US2012/066288 WO2013078335A1 (en) 2011-11-22 2012-11-21 Cysteamine and/or cystamine for treating ischemic injury

Publications (3)

Publication Number Publication Date
JP2014533701A JP2014533701A (ja) 2014-12-15
JP2014533701A5 JP2014533701A5 (OSRAM) 2016-01-21
JP6411215B2 true JP6411215B2 (ja) 2018-10-24

Family

ID=47297472

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014542590A Expired - Fee Related JP6411215B2 (ja) 2011-11-22 2012-11-21 虚血傷害を治療するためのシステアミンおよび／またはシスタミン

Country Status (16)

Country Link
US (1) US20140322315A1 (OSRAM)
EP (1) EP2782564B1 (OSRAM)
JP (1) JP6411215B2 (OSRAM)
KR (1) KR20140097132A (OSRAM)
CN (2) CN103974698A (OSRAM)
AU (1) AU2012340670B2 (OSRAM)
BR (1) BR112014012167A2 (OSRAM)
CA (1) CA2851387A1 (OSRAM)
HK (1) HK1202440A1 (OSRAM)
IL (1) IL232608A0 (OSRAM)
MX (1) MX2014004469A (OSRAM)
MY (1) MY165953A (OSRAM)
RU (1) RU2638807C2 (OSRAM)
SG (2) SG11201402472QA (OSRAM)
WO (1) WO2013078335A1 (OSRAM)
ZA (1) ZA201402290B (OSRAM)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
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AR096628A1 (es) * 2013-06-17 2016-01-20 Raptor Pharmaceuticals Inc Formulación en perlas de cisteamina de liberación retardada y métodos de preparación y uso de ella
AU2016288230A1 (en) 2015-07-02 2018-01-25 Horizon Orphan Llc ADO-resistant cysteamine analogs and uses thereof
CN106591461A (zh) * 2016-12-29 2017-04-26 天津协和华美医学诊断技术有限公司 一种检测遗传性易栓症相关基因群的检测试剂盒
US11020354B2 (en) 2017-01-19 2021-06-01 Otologic Pharmaceuticals, Inc. Formulations of n-acetylcysteine and uses thereof
WO2018140594A1 (en) * 2017-01-25 2018-08-02 Adare Pharmaceuticals, Inc. Cysteamine prodrugs
WO2021022012A1 (en) * 2019-07-30 2021-02-04 The Regents Of The University Of California Methods and composition for treating respiratory obstructive diseases
CN113484453B (zh) * 2021-07-07 2022-08-09 天津中医药大学 一种缺血性脑卒中预警方法

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FR2471186A1 (fr) 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
US4301146A (en) 1980-07-29 1981-11-17 G. D. Searle & Co. Stabilization of 16-oxygenated prostanoic acid derivatives
FR2549051B1 (fr) 1983-06-22 1986-05-16 Centre Nat Rech Scient Nouveaux agents radioprotecteurs ayant une structure amino-thioalkyle et procede pour leur preparation
FR2573077B1 (fr) * 1984-11-13 1987-02-13 Sanofi Sa Nouveaux derives thiosulfonates, leur procede de preparation ainsi que les compositions pharmaceutiques les contenant
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US5436255A (en) 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
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WO1997023202A1 (en) 1995-12-22 1997-07-03 STATE OF OREGON, acting by and through THE OREGON STATE BOARD OF HIGHER EDUCATION, acting for and on behalf of THE OREGON HEALTH SCIENCES UNIVERSITYA ND THE UNIVERSITY OF OREGON, EUGENE OREGON Subtype-selective nmda receptor ligands and the use thereof
ZA9610736B (en) 1995-12-22 1997-06-27 Warner Lambert Co 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists
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FR2753098B1 (fr) * 1996-09-06 1998-11-27 Sod Conseils Rech Applic Composition pharmaceutique comprenant au moins un inhibiteur de no synthase et au moins un piegeur des formes reactives de l'oxygene
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JP4976281B2 (ja) * 2004-05-03 2012-07-18 オメガ バイオ‐ファーマ（アイ．ピー．３）リミテッド 代謝を調節するための材料および方法
ES2417179T3 (es) * 2007-11-30 2013-08-06 The Regents Of The University Of California Métodos para tratar la esteatohepatitis no alcohólica (EHNA) mediante productos basados en cisteamina
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Also Published As

Publication number Publication date
CA2851387A1 (en) 2013-05-30
JP2014533701A (ja) 2014-12-15
AU2012340670B2 (en) 2016-12-22
EP2782564A1 (en) 2014-10-01
RU2014125282A (ru) 2015-12-27
IL232608A0 (en) 2014-06-30
HK1202440A1 (zh) 2015-10-02
CN108042517A (zh) 2018-05-18
AU2012340670A1 (en) 2014-04-17
RU2638807C2 (ru) 2017-12-15
KR20140097132A (ko) 2014-08-06
US20140322315A1 (en) 2014-10-30
ZA201402290B (en) 2017-06-28
EP2782564B1 (en) 2019-01-09
SG11201402472QA (en) 2014-06-27
CN103974698A (zh) 2014-08-06
BR112014012167A2 (pt) 2017-05-30
MY165953A (en) 2018-05-18
SG10201800159QA (en) 2018-02-27
WO2013078335A1 (en) 2013-05-30
MX2014004469A (es) 2014-08-01

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