JP6408886B2 - Reactor - Google Patents

Description

  The present invention relates to a reaction apparatus, and more particularly, to a reaction apparatus that introduces a plurality of reaction fluids from one end of a column packed with a reaction catalyst, causes the reaction in the column, and derives a reaction product from the other end of the column.

  Conventionally, as a reaction apparatus, a column stopper that closes an opening of a column is inserted into an inlet side of a column packed with a packing material through an annular sealing material, and is inserted into the outer periphery of the column inlet side and the outer periphery of the column stopper. A column for liquid chromatography in which a pair of flanges formed respectively is clamped with a clamp is known (for example, see Patent Document 1). In addition, as a reaction device that introduces a stock solution and a reaction gas from the inlet side of a column packed with a hydrogenation catalyst and causes a hydrogenation reaction to lead out reaction products from the other end of the column, it is provided on the inlet side and outlet side of the column. There was one in which the inlet side of the column was closed via an end fitting, a double ferrule member, a head, and a connector, and each pipe was connected (for example, see Patent Document 2). Furthermore, there is a type in which ferrule flanges are respectively formed on the opening side end portion and the end fitting of the column and joined in a state in which an annular sealing material is fitted in a fitting groove formed on the opposing surface (for example, Patent Documents). 3).

JP 2007-71730 A JP 2010-112907 A JP 2008-275071 A

  However, in the above-mentioned Patent Document 1, the column can be applied to a column made of resin such as polypropylene, but in the case of a metal column, the cleanly washed inner wall of the metal column is very slippery. It was extremely difficult to insert a column stopper equipped with an annular sealing material from the opening in the axial direction of the column. Furthermore, since the tip of the column stopper has entered the column, the packing amount of the packing material must be precisely controlled in order to bring the catalyst surface and the tip of the column stopper into close contact.

  Moreover, in the thing of patent document 2, since the screw coupling is used abundantly for the coupling | bonding of each member, the decomposition | disassembly operation | work for performing replacement | exchange of a catalyst or an internal washing | cleaning, and an assembly operation | work took the effort. Furthermore, since the end portion on the inlet side of the column is formed in a flat shape, there is a possibility that the packing material formed of fine powder spills from the end portion on the inlet side of the column during filling. Moreover, in the thing of patent document 3, a filler may enter into the fitting groove | channel of an annular sealing material, and the discharge | emission operation | work of the filler took time.

  Accordingly, an object of the present invention is to provide a reaction apparatus in which a column and a column end can be easily attached and detached, and a packing material can be easily filled and replaced.

  In order to achieve the above object, the reaction apparatus of the present invention has a column end connected to an opening on the inlet side and an opening on the outlet side of a column packed with a packing material via a disk-shaped filter covering the opening. Place each column end ferrule flange provided on the column mounting side of the column end on the column side ferrule flange formed on the outer periphery side of both openings of the column, and tighten with the ferrule clamp In the reaction apparatus in which the column and the column end are joined together, the column has a conical portion having a gradually increasing diameter toward the opening on the inner peripheral surface of the column-side ferrule flange. And a filter provided on the column side surface of the filter holding member having a diameter larger than the column inner diameter and smaller than the conical portion. The filter holding member is held in a holding recess, and a part of the filter holding member in the thickness direction is fitted into a fitting recess formed on a column side surface of the column end, and the filter holding member is annular on the outer periphery of the filter holding member protruding from the fitting recess A sealing material is disposed, and the column end includes a central port on the central axis of the column and an outer peripheral port on the outer peripheral side of the central port, and when the column and the column end are joined, An annular sealing material is in close contact with the conical portion and the column side surface of the column end to seal the column and the column end, and the central port and the outer peripheral port are connected to the inside of the column via the filter. It is characterized by communicating with.

  Further, it is preferable that an uneven engagement portion for engaging with each other and positioning the column and the column end is provided on the outer peripheral portion of the column side ferrule flange and the column end side ferrule flange.

  Further, the filter holding member on the inlet side is formed of a resin-made disk-shaped packing, and a through hole communicating with the central port is provided in the central portion, and the outer peripheral portion communicates with the outer peripheral port. An annular groove is provided, and a plurality of through holes communicating with the inside of the column through the filter on the inlet side are preferably provided at the bottom of the annular groove.

  The filter holding member on the outlet side is formed of a resin ring packing having an opening in the center and a cylindrical packing disposed in the opening of the ring packing, and the filter on the outlet side. Is formed in a disc shape having a fitting hole into which a cylindrical convex portion protruding from the upper surface of the cylindrical packing is fitted, and a temperature sensor inserted through the central port is connected to the cylindrical packing. The cylindrical packing is inserted into the column through the cylinder, the cylindrical projection is fitted into the fitting hole, and the column on the outlet side and the column end on the outlet side are joined. The outer periphery side port is in close contact with the joint recess to support the inner peripheral side, and the outer peripheral side port is formed between the cylindrical packing and the filter holding member on the outlet side, and the outlet side Filter and Preferably it communicates with the column and.

  Further, it is preferable that the filter holding member on the inlet side and the filter holding member on the outlet side have the same outer diameter and thickness.

  According to the reaction apparatus of the present invention, the filter is fitted to the filter holding member in the fitting recess provided in the column end so as to face the column mounting surface side, and the filter holding member protruding from the fitting recess has an annular shape on the protruding portion. With the sealing material in place, each column end ferrule flange is attached to the column side ferrule flange and tightened with a ferrule clamp, so that the annular sealing material is provided on the inner peripheral surface of the column side ferrule flange. Since it is in close contact with the column side of the inlet side column end or the outlet side column end, the column and the column end can be easily sealed. Thereby, a column and a column end can be easily attached or detached, and the exchange work of a filler and a filter can also be performed easily.

  Furthermore, since the conical portion is formed on the inner peripheral surface of the column-side ferrule flange, even when the packing material is filled or replaced, the packing material may contain air and rise from the column. By vibrating the column, the packing material can be satisfactorily accommodated in the column without spilling out of the column. Further, since it is not necessary to form a fitting groove for fitting the annular sealing material, there is no possibility that the filler enters the fitting groove, and the column and the column end can be easily cleaned.

  In addition, the outer periphery of the column-side ferrule flange and the column-end-side ferrule flange is provided with a concave and convex engaging portion that engages with each other to position the column and the column end. The center axis of the end can be easily matched.

  Furthermore, the filter holding member on the inlet side is formed of a resin disk-shaped packing, and an opening communicating with the central port is provided on the column mounting surface side of the central portion, and the outer periphery is provided on the column mounting surface side of the outer peripheral portion. An annular groove that communicates with the side port is provided, and a plurality of communication holes that communicate with the inside of the column via the filter on the inlet side are provided at the bottom of the annular groove. Since it is introduced into the column separately from the port, there is no problem due to the reaction occurring before the column introduction.

  The outlet-side filter holding member is formed of a resin ring packing having an opening in the center and a cylindrical packing disposed in the opening of the ring packing, and the outlet filter has an outer periphery. Since the side is supported by the ring packing and the inner peripheral side is supported by the cylindrical packing, the strength of the filter can be maintained even when the weight of the packing material packed in the column is applied to the filter. Furthermore, the temperature sensor can be favorably held at the center of the column.

  Furthermore, by forming the outer diameter dimension and the thickness dimension of the inlet side filter holding member and the outlet side filter holding member to be the same, the fitting recesses provided in the inlet side column end and the outlet side column end are the same. The shape can be achieved, and the manufacturing cost can be reduced.

It is sectional drawing of the reaction apparatus which shows the 1st form example of this invention. It is an exploded perspective view of a reactor similarly. It is a principal part sectional view which similarly shows the entrance side of a column. It is a principal part sectional view which similarly shows the exit side of a column. It is principal part sectional drawing which shows the inlet side of the column which shows the 2nd form example of this invention.

  FIG. 1 to FIG. 4 are diagrams showing a first embodiment of the reaction apparatus of the present invention. In this embodiment, as a reaction apparatus, a stock solution (substrate) as a first reaction fluid and hydrogen gas (a second fluid) ( Reaction gas) through a column packed with a solid hydrogenation catalyst with a particle size of several tens of μm, and the column is maintained at a preset temperature to react the stock solution with hydrogen gas. The hydrogenation reactor which performs the hydrogenation process of a stock solution is illustrated.

  The hydrogenation reactor 11 includes a column 12 filled with a hydrogenation catalyst, column ends 13 and 13 provided at both ends of the column 12, and an inlet side filter 14 fitted to the column end 13 on the inlet side. The fitted inlet side filter holding member 15, the outlet side filter holding member 17 having the outlet side filter 16 fitted to the outlet side column end 13, the column 12, and the column ends 13 and 13, respectively. O-rings 18 and 18 (annular sealing material of the present invention) for sealing, and ferrule clamps 19 and 19 for joining the column 12 and the column ends 13 and 13 are provided.

  The column 12 includes a tubular column main body portion 12a formed of a metal material such as stainless steel, and column-side ferrule flanges 12b and 12b provided on both ends of the column main body portion 12a. Each column side ferrule flange 12b has a flat end on the end face (butting face) facing the column end 13, a slope on the opposite end side, and a thicker inner peripheral side of the flange than the outer peripheral side of the flange. Further, an annular convex engaging portion 12c formed by projecting the end surface side toward the column end 13 is provided on the outer peripheral portion of the column side ferrule flange 12b. Furthermore, on the inner peripheral surface of the column-side ferrule flange 12b, a flat surface portion 12d formed on the outer peripheral side of the column opening portion, and formed on the outer peripheral side of the flat surface portion 12d, gradually increasing in diameter toward the column opening portion. And a conical portion 12e having an inclination angle of about 45 degrees.

  The column end 13 includes a substantially cylindrical main body 13a, a column end ferrule flange 13b provided on the column mounting side outer periphery of the main body 13a, and a circular fitting recess 13e provided on the column side surface 13c. Have. The column end-side ferrule flange 13b has a flat surface on the surface (butting surface) facing the column-side ferrule flange 12b, an inclined surface on the opposite end surface side, and a thicker inner periphery on the flange outer periphery side. Further, the outer peripheral portion of the column end side ferrule flange 13b is provided with a concave engagement portion 13d that is recessed in a stepped manner on the end surface side and engaged with the convex engagement portion 12c. The outer peripheral surface of the portion 13d and the inner peripheral surface of the convex engaging portion 12c are in contact with each other so that the central axis of the column 12 and the central axis of the column end 13 coincide. The column end 13 is provided with a central port 20 having a female threaded portion 20a at a central portion that coincides with the column axis, and an outer peripheral port 21 having a female threaded portion 21a at the outer peripheral portion. The fitting recess 13e has an inner diameter larger than the inner diameter of the column 12, and is formed to a depth that allows a part of the inlet-side filter holding member 15 or the outlet-side filter holding member 17 to be fitted in the thickness direction. Yes.

  The inlet-side filter 14 has a thickness of about 1.7 mm by laminating a plurality of disk-shaped mesh materials having a diameter larger than the inner diameter of the column 12, for example, a stainless steel mesh material having a diameter of about 10 μm. Is formed. Further, the mesh of the mesh material may be set according to the properties of the hydrogenation catalyst packed in the column 12, the number of stacked layers can also be set appropriately, and the number of meshes and the number of stacked layers can be set on the inlet side and the outlet side. May be different.

  The inlet-side filter holding member 15 has a diameter larger than the diameter of the inlet-side filter 14 and the column 12 and falls when a part in the thickness direction is fitted in the fitting recess 13e provided in the column end 13. In order to hold the inlet-side filter 14 on the surface that becomes the column mounting surface side when it is attached to the column end 13, it is formed of a fluororesin disk-shaped packing having a diameter that can obtain a fitting force that does not allow the fitting A circular filter holding recess 15a is provided. Further, the inlet-side filter holding member 15 is set so that the other half portion in the thickness direction protrudes to the column 12 side when one half portion in the thickness direction is inserted into the fitting recess 13e.

  Further, a through hole 15b communicating with the central port 20 of the column end 13 is formed in a conical shape with the column mounting surface side widened in the central portion of the inlet side filter holding member 15, and the outer peripheral side port 21 is connected to the outer peripheral portion. An annular groove 15c that communicates is provided, and a plurality of communication holes 15d that communicate with the column 12 via the inlet-side filter 14 are provided at equal intervals in the circumferential direction at the bottom of the annular groove 15c. The inlet-side filter holding member 15 into which the inlet-side filter 14 has been press-fitted is press-fitted into the fitting recess 13e of the column end 13, whereby the inlet-side filter 14, the inlet-side filter holding member 15 and the column end 13 are integrated. It becomes a state.

  The outlet side filter 16 has a diameter larger than the inner diameter of the column 12, and is formed to have a thickness of about 1.7 mm by laminating and pressing the mesh material in the same manner as the inlet side filter 14, and is fitted in the center portion. A hole 16a is formed.

  The outlet side filter holding member 17 includes a ring-shaped packing 17a made of a fluororesin having a diameter larger than the diameters of the inlet-side filter 14 and the column 12, and a cylindrical packing 22 disposed at an opening of the ring-shaped packing 17a. It is formed with. The ring-shaped packing 17a is larger than the diameter of the outlet filter 16 and the diameter of the column 12, and drops when a part of the thickness direction is fitted into the fitting recess 13e provided in the column end 13. It has a diameter that can provide a fitting force that does not occur. Further, the ring-shaped packing 17 a is provided with a circular filter holding recess 17 b for holding the outer peripheral side of the outlet side filter 16 on the surface which becomes the column mounting surface side when attached to the column end 13. Similarly to the inlet-side filter holding member 15, the ring-shaped packing 17 a projects the other half in the thickness direction toward the column 12 when one half in the thickness direction is inserted into the fitting recess 13 e. The inlet side filter holding member 15 has the same outer diameter and thickness.

  The cylindrical packing 22 is made of a fluororesin like the ring packing 17a, and is formed on the cylindrical convex portion 22a inserted into the fitting hole 16a, the column end side surface of the outlet side filter 16, and the bottom portion of the fitting concave portion 13e. The outlet side filter holding member 17 has the same thickness as the outlet side filter holding member 17. Further, a sensor insertion hole 22 c for inserting a temperature sensor that communicates with the central port 20 is formed through the central portion of the cylindrical packing 22.

  The O-ring 18 is attached to the outer periphery of the protrusion 15e of the inlet-side filter holding member 15 and the outer periphery of the protrusion 17c of the outlet-side filter holding member 17 that are press-fitted into the fitting recess 13e. The inner diameter of the ring is set to be slightly smaller than the outer diameter of each protrusion 15e, 17c. The diameter of the O-ring 18 is such that when the column ends 13 and 13 are joined to the column 12, the O-ring 18 is in close contact with the conical portion 12 e formed on the column 12 and the column side surfaces 13 c and 13 c of the column ends 13 and 13. Is set.

  The ferrule clamp 19 includes a pair of clamp arms 19a and 19a whose base ends are connected to each other via a connecting member so that the front ends can be opened and closed, and fastening ends that fasten the ends of the clamp arms 19a and 19a. A clamping groove 19c having a trapezoidal cross section for fastening the column side ferrule flange 12b and the column end side ferrule flange 13b is provided on the inner circumference of each clamp arm 19a, 19a. ing.

  Next, an example of the assembly procedure of the hydrogenation reactor 11 will be described. First, the inlet-side filter holding member 15 holding the inlet-side filter 14 is fitted into the fitting recess 13e of one column end 13 with the inlet-side filter 14 facing forward, and the inlet protruding from the fitting recess 13e. An O-ring 18 is attached to the outer periphery of the protruding portion 15e of the side filter holding member.

  Further, the outlet side filter 16 is held by the ring-shaped packing 17 a, and on the other hand, the sensor insertion hole 22 c of the cylindrical packing 22 is passed through the temperature sensor 24 inserted through the central port 20 of the column end 13 on the outlet side. The cylindrical convex portion 22 a is fitted into the fitting hole 16 a of the outlet side filter 16. Next, the outlet-side filter holding member 17 is fitted into the fitting recess 13e of the other column end 13 with the outlet-side filter 16 facing forward, and the outlet-side filter holding member 17 protrudes from the fitting recess 13e. An O-ring 18 is attached to the outer periphery of the portion 17c.

  Next, the column end 13 to which the outlet side filter holding member 17, the temperature sensor 24, and the O-ring 18 are respectively attached is arranged at one end of the column 12, and the concave engagement portion 13 d and the convex engagement portion 12 c are recessed and fitted. The clamp arms 19a and 19a are arranged on the outer circumferences of the column-side ferrule flange 12b and the column-end-side ferrule flange 13b with the flat-plate-like ferrule clamp 19 attached to each other, and the clamp arms 19a and 19a are positioned. The column end 13 on the outlet side is fixed to the outlet end of the column 12 by the ferrule clamp 19 by closing the wing nut of the fastening member 19b. At this time, the column side surface of the outlet side filter holding member 17 abuts on a flat surface portion 12d formed on the inner surface of the column side ferrule flange 12b, and the O-ring 18 is formed between the conical portion 12e formed on the column 12 and the column end 13. The column 12 is in close contact with the column side surface 13c, and the column 12 and the column end 13 on the outlet side are sealed. Further, when the concave engaging portion 13d and the convex engaging portion 12c are engaged with each other, the central axis of the column 12 and the central axis of the column end 13 coincide with each other. Further, the cylindrical packing 22 is in close contact with the bottom of the fitting recess 13e, the outer peripheral side of the outlet filter 16 is supported by the ring packing 17a, and the inner peripheral side is supported by the cylindrical packing 22. Further, the outer peripheral port 21 communicates with the inside of the column 12 via the hollow portion 23 formed between the ring-shaped packing 17 a and the cylindrical packing 22 and the outlet-side filter 16.

  Then, a male screw connector 25 is screwed onto the female screw portion 20a of the central port 20 to fix the temperature sensor 24, and a reaction product outlet pipe 26 for leading a reaction product is connected to the outer peripheral side port 21. 27 is fixed.

  Subsequently, a hydrogenation catalyst is introduced from the inlet side of the column 12 and filled in the column 12. At this time, since the hydrogenation catalyst is a fine powder and contains air when poured, it must be packed in small portions while vibrating the column 12 in order to remove the air, but the column-side ferrule flange 12b. Since the conical portion 12e having a gradually increasing diameter toward the opening is provided on the inner surface of the column, the hydrogenation catalyst can be satisfactorily accommodated in the column 12 without spilling out of the column 12. Also, the overflowing hydrogenation catalyst can be easily removed. After the catalyst is packed, the column end ferrule flange 19 is attached by the ferrule clamp 19 in a state in which the column end 13 is arranged by mounting the inlet side filter holding member 15 on the inlet side of the column 12 and is positioned by the concave and convex engagement like the outlet side. 12 b and the column end ferrule flange 13 b are tightened to fix the column end 13 on the inlet side to the inlet end of the column 12. At this time, the column side surface of the inlet-side filter holding member 15 abuts on a flat surface portion 12d formed on the inner surface of the column-side ferrule flange 12b, and the O-ring 18 is formed between the conical portion 12e formed on the column 12 and the column end 13. The column 12 is in close contact with the column side surface 13c, the column 12 and the column end 13 on the inlet side are sealed, and the hydrogenation catalyst can be securely held in the column 12, and the hydrogenation catalyst leaks from the gap with the column end 13. I do not put out. When the column 12 is filled with the hydrogenation catalyst, the weight of the hydrogenation catalyst is applied to the outlet side filter 16. The outlet side filter 16 is supported by the cylindrical packing 22 at the center, and the outlet side filter holding member at the outer peripheral side. 17, there is no possibility that the outlet side filter 16 is deformed.

  Finally, the first reaction fluid introduction pipe 28 for introducing the stock solution is connected to the central port 20 of the column end 13 on the inlet side by the male screw connector 29, and the second reaction fluid introduction for introducing hydrogen gas to the outer peripheral side port 21 is connected. The tube 30 is connected by a male screw connector 31. At this time, it is preferable that the tip of the first reaction fluid introduction pipe 28 for introducing the stock solution is inserted into the vicinity of the inlet side filter through the through hole 15b of the inlet side filter holding member 15.

  Thereby, the preparation of the hydrogenation reactor 11 is completed. Furthermore, by performing preparatory work such as installing a thermostat on the outer periphery of the column 12, the hydrogenation treatment of the stock solution can be started. The stock solution during the hydrogenation process passes through the center of the inlet side filter 14 from the first reaction fluid introduction pipe 28 and flows into the column 12, and the hydrogen gas is held in the inlet side filter from the second reaction fluid introduction pipe 30. After being introduced into the annular groove 15 c of the member 15, it flows into the column 12 from the plurality of communication holes 15 d so as to surround the periphery of the stock solution from the outer peripheral side of the inlet side filter 14. On the other hand, the reaction product (raw hydride) generated in the column 12 flows into the hollow portion 23 through the outlet side filter 16 and is led out from the outer peripheral side port 21 to the reaction product outlet pipe 26. When the life of the catalyst is exhausted, the catalyst may be replaced by decomposing in the reverse procedure.

  FIG. 5 shows another embodiment of the present invention. Components that are the same as those in the first embodiment are denoted by the same reference numerals, and detailed description thereof is omitted. In this embodiment, two outer peripheral ports 21 and 21 are formed in the column end 13 on the inlet side, and the second reaction fluid introduction pipe 30 is connected to one outer peripheral port 21 via a male screw connector 31. A third reaction fluid introduction pipe 32 is connected to the other outer peripheral side port 21 via a male screw connector 33, and three kinds of reaction fluids can be introduced into the column 12.

  As in each of the above-described embodiments, the inlet side filter holding member 15, the inlet side filter 14, and the O-ring 18 are attached to and integrated with the column end 13 on the inlet side, and the outlet side filter is attached to the column end 13 on the outlet side. The holding member 17, the outlet side filter 16, and the O-ring 18 are attached and integrated, and the column-side ferrule flange 12 b and the column-end side ferrule flange 13 b are attached to each other and fastened with a ferrule clamp 19 to join together. 18 and 18 are in close contact with the conical portion 12e provided on the inner peripheral surface of the column side ferrule flange 12b and the column side surfaces 13c and 13c of the column ends 13 and 13, respectively, so that the column 12 and the column end 13 can be easily attached and detached. Can be made. Further, the conical portion 12e formed on the inner peripheral surface of the column-side ferrule flange 12b allows the hydrogenation catalyst to be satisfactorily accommodated in the column 12 without spilling out of the column 12 when the hydrogenation catalyst is charged or replaced. it can. Further, since it is not necessary to form a fitting groove for fitting the O-ring 18, there is no possibility that the hydrogenation catalyst enters the fitting groove, and the column 12 and the column end 13 can be easily cleaned.

  Further, an annular convex engaging portion 12c and a concave shape for engaging the outer peripheral portions of the column side ferrule flange 12b and the column end side ferrule flange 13b with each other to position the column 12 and the column ends 13, 13. By providing the engaging portion 13d, the central axis of the column 12 and the central axis of the column end 13 can be easily matched. Furthermore, since the reaction fluid is separately introduced into the column 12 from the central port 20 and the outer peripheral port 21 on the inlet side, there is no problem due to the reaction occurring before the column introduction. Further, the outlet side filter 16 can be supported by the cylindrical packing 22 on the inner peripheral side, and the outlet side filter 16 is deformed even when the weight of the hydrogenation catalyst packed in the column 12 is applied to the outlet side filter 16. There is no fear of doing it. Further, the outer diameter dimension and the thickness dimension of the inlet side filter holding member 15 and the outlet side filter holding member 17 are formed to be the same, and the column end 13 on the inlet side and the column end 13 on the outlet side are formed in the same shape. As a result, the manufacturing cost can be reduced.

  In addition, this invention is not restricted to each above-mentioned form example, The direction of an uneven | corrugated fitting part may be reverse. Furthermore, in the above-described embodiment, the column ends have the same shape, but different shapes of column ends may be used for the inlet and the outlet.

DESCRIPTION OF SYMBOLS 11 ... Hydrogenation reactor, 12 ... Column, 12a ... Column main-body part, 12b ... Column side ferrule flange, 12c ... Convex engagement part, 12d ... Plane part, 12e ... Conical part, 13 ... Column end, 13a ... Main-body part , 13b ... column end side ferrule flange, 13c ... column side, 13d ... concave engagement part, 13e ... fitting concave part, 14 ... inlet side filter, 15 ... inlet side filter holding member, 15a ... filter holding concave part, 15b ... through Hole, 15c ... annular groove, 15d ... communication hole, 15e ... projecting part, 16 ... outlet side filter, 16a ... fitting hole, 17 ... outlet side filter holding member, 17a ... ring packing, 17b ... filter holding recess, 17c ... Projection, 18 ... O-ring, 19 ... Ferrule clamp, 19a ... Clamp arm, 19b ... Fastening member, 19c ... Clamping groove, 20 ... Medium Port, 20a ... Female thread portion, 21 ... Outer peripheral port, 21a ... Female thread portion, 22 ... Cylindrical packing, 22a ... Cylindrical convex portion, 22b ... Large diameter portion, 22c ... Sensor insertion hole, 23 ... Hollow portion, 24 ... Temperature sensor, 25, 27, 29, 31 ... male screw connector, 26 ... reaction product outlet tube, 28 ... first reaction fluid introduction tube, 30 ... second reaction fluid introduction tube, 31 ... male screw connector, 32 ... third reaction Fluid introduction pipe, 33 ... male screw connector

Claims (5)

Column ends are respectively arranged in the opening on the inlet side and the opening on the outlet side of the column filled with the packing material through a disk-like filter covering the opening, and the outer peripheral sides of both openings of the column In each of the column side ferrule flanges formed on the column end, the column end side ferrule flanges provided on the column mounting side of the column end are attached to each other and tightened with a ferrule clamp to join the column and the column end,
The column is formed with a conical portion gradually increasing in diameter toward the opening on the inner peripheral surface of the column-side ferrule flange,
The filter is held in a filter holding recess provided on a column side surface of a filter holding member that is larger in diameter than the filter and the inner diameter of the column and smaller in diameter than the conical part,
In the filter holding member, a part of the thickness direction is fitted into a fitting recess formed on the column side surface of the column end, and an annular sealing material is disposed on the outer periphery of the filter holding member protruding from the fitting recess,
The column end includes a central port on the central axis of the column, and an outer peripheral port on the outer peripheral side of the central port,
When the column and the column end are joined, the annular sealing material is in close contact with the conical portion and the column side surface of the column end to seal the column and the column end, and the central port And the outer peripheral side port communicate with each other in the column through the filter.   An uneven engagement portion for engaging with each other and positioning the column and the column end is provided on outer peripheral portions of the column side ferrule flange and the column end side ferrule flange. Item 2. The reaction apparatus according to Item 1.   The filter holding member on the inlet side is formed of a resin disk packing, a through hole communicating with the central port is provided in the central portion, and an annular groove communicating with the outer peripheral port is formed in the outer peripheral portion. The reaction apparatus according to claim 1 or 2, wherein a plurality of through holes communicating with the inside of the column through the filter on the inlet side are provided at the bottom of the annular groove. The filter holding member on the outlet side is formed of a resin-made ring-shaped packing having an opening at the center, and a cylindrical packing disposed in the opening of the ring-shaped packing,
The filter on the outlet side is formed in a disc shape having a fitting hole into which a cylindrical convex portion protruding from the upper surface of the cylindrical packing is fitted in the center portion,
The temperature sensor inserted through the central port is inserted into the column through the cylinder of the cylindrical packing, the cylindrical convex portion is fitted into the fitting hole, the column on the outlet side and the column on the outlet side When the column end is joined, the cylindrical packing closely contacts the fitting recess to support the inner peripheral side of the filter, and the outer peripheral port holds the filter on the cylindrical packing and the outlet side. The reaction apparatus according to claim 1 or 2, wherein the reaction apparatus communicates with the inside of the column through a hollow portion formed between the members and the filter on the outlet side.   The reactor according to any one of claims 1 to 4, wherein the filter holding member on the inlet side and the filter holding member on the outlet side have the same outer diameter and thickness.

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