JP6366696B2 - Ｓ−［４−（３−フルオロ−３−メチルブチリルオキシ）ブタ−２−イニル］６α，９α−ジフルオロ−１７α−（フラン−２−イル）カルボニルオキシ−１１β−ヒドロキシ−１６α−メチル−３−オキソアンドロスタ−１，４−ジエン−１７β−カルボチオアートを使用する炎症性病態の治療の方法 - Google Patents
Ｓ−［４−（３−フルオロ−３−メチルブチリルオキシ）ブタ−２−イニル］６α，９α−ジフルオロ−１７α−（フラン−２−イル）カルボニルオキシ−１１β−ヒドロキシ−１６α−メチル−３−オキソアンドロスタ−１，４−ジエン−１７β−カルボチオアートを使用する炎症性病態の治療の方法 Download PDFInfo
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1881MU2013 | 2013-05-28 | ||
| IN1881/MUM/2013 | 2013-05-28 | ||
| PCT/IN2014/000359 WO2014192027A1 (en) | 2013-05-28 | 2014-05-28 | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl] 6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
Publications (3)
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| JP2016520122A JP2016520122A (ja) | 2016-07-11 |
| JP2016520122A5 JP2016520122A5 (enExample) | 2017-06-08 |
| JP6366696B2 true JP6366696B2 (ja) | 2018-08-01 |
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| JP2016516309A Expired - Fee Related JP6366696B2 (ja) | 2013-05-28 | 2014-05-28 | Ｓ−［４−（３−フルオロ−３−メチルブチリルオキシ）ブタ−２−イニル］６α，９α−ジフルオロ−１７α−（フラン−２−イル）カルボニルオキシ−１１β−ヒドロキシ−１６α−メチル−３−オキソアンドロスタ−１，４−ジエン−１７β−カルボチオアートを使用する炎症性病態の治療の方法 |
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| EP (1) | EP3004133B1 (enExample) |
| JP (1) | JP6366696B2 (enExample) |
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| CN (1) | CN105431445A (enExample) |
| AU (1) | AU2014272640B2 (enExample) |
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| UA (1) | UA117248C2 (enExample) |
| WO (1) | WO2014192027A1 (enExample) |
| ZA (1) | ZA201508640B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3004133B1 (en) | 2013-05-28 | 2018-03-07 | Sun Pharma Advanced Research Company Limited | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl]6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
| SG11201706104XA (en) * | 2015-01-31 | 2017-08-30 | Sun Pharma Advanced Res Co Ltd | CRYSTALLINE FORM OF S-(4-(3-FLUORO-3-METHYLBUTYRYLOXY)BUT-2-YNYL)6a,9a-DIFLUORO-17a,-(FURAN-2-YL)CARBONYLOXY-11ß-HYDROXY-16a-METHY1-3-OXOANDROSTA-1,4-DIENE-17ß-CARBOTHIOATE |
| CN106279341A (zh) * | 2015-05-11 | 2017-01-04 | 正大天晴药业集团股份有限公司 | 一种糠酸氟替卡松的制备方法 |
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| JPS56138200A (en) | 1980-02-15 | 1981-10-28 | Glaxo Group Ltd | Androstane carbothioate compound |
| WO2004001369A2 (en) | 2002-06-20 | 2003-12-31 | Sun Pharmaceutical Industries Limited | Convenient synthesis of s-fluoromethyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha- methyl-17alpha-propionyloxy-3-oxoandrosta-1, 4-diene-17beta-carbothioate |
| GB0225287D0 (en) | 2002-10-30 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| AR059216A1 (es) * | 2006-01-27 | 2008-03-19 | Sun Pharmaceutical Ind Ltd | 11b-hidroxiandrosta-4-eno-3-onas |
| EP3004133B1 (en) | 2013-05-28 | 2018-03-07 | Sun Pharma Advanced Research Company Limited | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl]6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
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2014
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- 2014-05-28 MX MX2015016283A patent/MX2015016283A/es unknown
- 2014-05-28 UA UAA201512888A patent/UA117248C2/uk unknown
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- 2014-05-28 JP JP2016516309A patent/JP6366696B2/ja not_active Expired - Fee Related
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- 2014-05-28 KR KR1020157033778A patent/KR20160030085A/ko not_active Withdrawn
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2014192027A1 (en) | 2014-12-04 |
| EA027831B1 (ru) | 2017-09-29 |
| EP3004133A1 (en) | 2016-04-13 |
| IL242658A0 (en) | 2016-02-01 |
| BR112015029530A2 (pt) | 2017-07-25 |
| US20160102117A1 (en) | 2016-04-14 |
| KR20160030085A (ko) | 2016-03-16 |
| MX2015016283A (es) | 2016-03-11 |
| JP2016520122A (ja) | 2016-07-11 |
| UA117248C2 (uk) | 2018-07-10 |
| CA2912400A1 (en) | 2014-12-04 |
| ES2664019T3 (es) | 2018-04-18 |
| PH12015502652A1 (en) | 2016-03-07 |
| AU2014272640A1 (en) | 2015-11-26 |
| EP3004133B1 (en) | 2018-03-07 |
| CN105431445A (zh) | 2016-03-23 |
| BR112015029530A8 (pt) | 2019-12-17 |
| MY179214A (en) | 2020-11-02 |
| ZA201508640B (en) | 2017-09-27 |
| SG11201509680TA (en) | 2015-12-30 |
| EA201592283A1 (ru) | 2016-04-29 |
| AU2014272640B2 (en) | 2018-04-05 |
| EA027831B9 (ru) | 2017-12-29 |
| US9458187B2 (en) | 2016-10-04 |
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