CA2912400A1 - Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy)but-2-ynyl]6.alpha.,9.alpha.-difluoro-17.alpha.-(furan-2-yl)carbonyloxy-11.beta.-hydroxy-16.alpha.-methyl-3-oxoandrosta-1,4-diene-17.beta.-carbothioate - Google Patents
Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy)but-2-ynyl]6.alpha.,9.alpha.-difluoro-17.alpha.-(furan-2-yl)carbonyloxy-11.beta.-hydroxy-16.alpha.-methyl-3-oxoandrosta-1,4-diene-17.beta.-carbothioateInfo
- Publication number
- CA2912400A1 CA2912400A1 CA2912400A CA2912400A CA2912400A1 CA 2912400 A1 CA2912400 A1 CA 2912400A1 CA 2912400 A CA2912400 A CA 2912400A CA 2912400 A CA2912400 A CA 2912400A CA 2912400 A1 CA2912400 A1 CA 2912400A1
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- Canada
- Prior art keywords
- compound
- formula
- human
- alpha
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/02—Nasal agents, e.g. decongestants
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
Landscapes
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1881MU2013 | 2013-05-28 | ||
| IN1881/MUM/2013 | 2013-05-28 | ||
| PCT/IN2014/000359 WO2014192027A1 (en) | 2013-05-28 | 2014-05-28 | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl] 6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
Publications (1)
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|---|---|
| CA2912400A1 true CA2912400A1 (en) | 2014-12-04 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2912400A Abandoned CA2912400A1 (en) | 2013-05-28 | 2014-05-28 | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy)but-2-ynyl]6.alpha.,9.alpha.-difluoro-17.alpha.-(furan-2-yl)carbonyloxy-11.beta.-hydroxy-16.alpha.-methyl-3-oxoandrosta-1,4-diene-17.beta.-carbothioate |
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| EP (1) | EP3004133B1 (enExample) |
| JP (1) | JP6366696B2 (enExample) |
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| CA (1) | CA2912400A1 (enExample) |
| EA (1) | EA027831B9 (enExample) |
| ES (1) | ES2664019T3 (enExample) |
| IL (1) | IL242658A0 (enExample) |
| MX (1) | MX2015016283A (enExample) |
| MY (1) | MY179214A (enExample) |
| PH (1) | PH12015502652A1 (enExample) |
| SG (1) | SG11201509680TA (enExample) |
| UA (1) | UA117248C2 (enExample) |
| WO (1) | WO2014192027A1 (enExample) |
| ZA (1) | ZA201508640B (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3004133B1 (en) | 2013-05-28 | 2018-03-07 | Sun Pharma Advanced Research Company Limited | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl]6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
| SG11201706104XA (en) * | 2015-01-31 | 2017-08-30 | Sun Pharma Advanced Res Co Ltd | CRYSTALLINE FORM OF S-(4-(3-FLUORO-3-METHYLBUTYRYLOXY)BUT-2-YNYL)6a,9a-DIFLUORO-17a,-(FURAN-2-YL)CARBONYLOXY-11ß-HYDROXY-16a-METHY1-3-OXOANDROSTA-1,4-DIENE-17ß-CARBOTHIOATE |
| CN106279341A (zh) * | 2015-05-11 | 2017-01-04 | 正大天晴药业集团股份有限公司 | 一种糠酸氟替卡松的制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56138200A (en) | 1980-02-15 | 1981-10-28 | Glaxo Group Ltd | Androstane carbothioate compound |
| WO2004001369A2 (en) | 2002-06-20 | 2003-12-31 | Sun Pharmaceutical Industries Limited | Convenient synthesis of s-fluoromethyl 6alpha, 9alpha-difluoro-11beta-hydroxy-16alpha- methyl-17alpha-propionyloxy-3-oxoandrosta-1, 4-diene-17beta-carbothioate |
| GB0225287D0 (en) | 2002-10-30 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| AR059216A1 (es) * | 2006-01-27 | 2008-03-19 | Sun Pharmaceutical Ind Ltd | 11b-hidroxiandrosta-4-eno-3-onas |
| EP3004133B1 (en) | 2013-05-28 | 2018-03-07 | Sun Pharma Advanced Research Company Limited | Methods for treatment of inflammatory conditions using s-[4-(3-fluoro-3-methylbutyryloxy) but-2-ynyl]6alpha, 9alpha-difluoro-17alpha-(furan-2-yl) carbonyloxy-11beta -hydroxy-16alpha-methyl-3-oxoandrosta-1,4-diene-17beta -carbothioate. |
-
2014
- 2014-05-28 EP EP14750012.8A patent/EP3004133B1/en not_active Not-in-force
- 2014-05-28 MX MX2015016283A patent/MX2015016283A/es unknown
- 2014-05-28 UA UAA201512888A patent/UA117248C2/uk unknown
- 2014-05-28 SG SG11201509680TA patent/SG11201509680TA/en unknown
- 2014-05-28 US US14/893,655 patent/US9458187B2/en not_active Expired - Fee Related
- 2014-05-28 JP JP2016516309A patent/JP6366696B2/ja not_active Expired - Fee Related
- 2014-05-28 EA EA201592283A patent/EA027831B9/ru not_active IP Right Cessation
- 2014-05-28 CN CN201480030607.2A patent/CN105431445A/zh active Pending
- 2014-05-28 AU AU2014272640A patent/AU2014272640B2/en not_active Ceased
- 2014-05-28 CA CA2912400A patent/CA2912400A1/en not_active Abandoned
- 2014-05-28 KR KR1020157033778A patent/KR20160030085A/ko not_active Withdrawn
- 2014-05-28 MY MYPI2015704326A patent/MY179214A/en unknown
- 2014-05-28 BR BR112015029530A patent/BR112015029530A8/pt not_active Application Discontinuation
- 2014-05-28 WO PCT/IN2014/000359 patent/WO2014192027A1/en not_active Ceased
- 2014-05-28 ES ES14750012.8T patent/ES2664019T3/es active Active
-
2015
- 2015-11-18 IL IL242658A patent/IL242658A0/en unknown
- 2015-11-24 ZA ZA2015/08640A patent/ZA201508640B/en unknown
- 2015-11-26 PH PH12015502652A patent/PH12015502652A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014192027A1 (en) | 2014-12-04 |
| EA027831B1 (ru) | 2017-09-29 |
| EP3004133A1 (en) | 2016-04-13 |
| IL242658A0 (en) | 2016-02-01 |
| BR112015029530A2 (pt) | 2017-07-25 |
| US20160102117A1 (en) | 2016-04-14 |
| KR20160030085A (ko) | 2016-03-16 |
| MX2015016283A (es) | 2016-03-11 |
| JP2016520122A (ja) | 2016-07-11 |
| UA117248C2 (uk) | 2018-07-10 |
| ES2664019T3 (es) | 2018-04-18 |
| PH12015502652A1 (en) | 2016-03-07 |
| AU2014272640A1 (en) | 2015-11-26 |
| EP3004133B1 (en) | 2018-03-07 |
| CN105431445A (zh) | 2016-03-23 |
| BR112015029530A8 (pt) | 2019-12-17 |
| MY179214A (en) | 2020-11-02 |
| ZA201508640B (en) | 2017-09-27 |
| SG11201509680TA (en) | 2015-12-30 |
| EA201592283A1 (ru) | 2016-04-29 |
| JP6366696B2 (ja) | 2018-08-01 |
| AU2014272640B2 (en) | 2018-04-05 |
| EA027831B9 (ru) | 2017-12-29 |
| US9458187B2 (en) | 2016-10-04 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |
Effective date: 20200831 |