JP6363595B2 - 歯周炎および歯周炎に関連する疾患を処置または予防する方法 - Google Patents

歯周炎および歯周炎に関連する疾患を処置または予防する方法 Download PDF

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JP6363595B2
JP6363595B2 JP2015518554A JP2015518554A JP6363595B2 JP 6363595 B2 JP6363595 B2 JP 6363595B2 JP 2015518554 A JP2015518554 A JP 2015518554A JP 2015518554 A JP2015518554 A JP 2015518554A JP 6363595 B2 JP6363595 B2 JP 6363595B2
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periodontitis
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porphyromonas gingivalis
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ジョージ・ハジシェンガリス
ジョン・ディ・ランブリス
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ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア
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    • G01N2333/47Assays involving proteins of known structure or function as defined in the subgroups
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    • G01N2333/4716Complement proteins, e.g. anaphylatoxin, C3a, C5a
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
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JP2015518554A 2012-06-20 2013-06-19 歯周炎および歯周炎に関連する疾患を処置または予防する方法 Active JP6363595B2 (ja)

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US201261662022P 2012-06-20 2012-06-20
US61/662,022 2012-06-20
US13/801,096 2013-03-13
US13/801,096 US9579360B2 (en) 2012-06-20 2013-03-13 Methods of treating or preventing periodontitis and diseases associated with periodontitis
PCT/US2013/046599 WO2013192319A1 (en) 2012-06-20 2013-06-19 Methods of treating or preventing periodontitis and diseases associated with periodontitis

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JP2015523999A JP2015523999A (ja) 2015-08-20
JP6363595B2 true JP6363595B2 (ja) 2018-07-25

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US (2) US9579360B2 (en, 2012)
EP (1) EP2863949B1 (en, 2012)
JP (1) JP6363595B2 (en, 2012)
CN (1) CN104640567A (en, 2012)
AU (1) AU2013277217B2 (en, 2012)
CA (1) CA2877299C (en, 2012)
IN (1) IN2015DN00438A (en, 2012)
WO (1) WO2013192319A1 (en, 2012)

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US9579360B2 (en) * 2012-06-20 2017-02-28 The Trustees Of The University Of Pennsylvania Methods of treating or preventing periodontitis and diseases associated with periodontitis
CN106456605A (zh) 2014-02-25 2017-02-22 艾其林医药公司 用于治疗补体介导的疾病的氨基化合物
AP2016009612A0 (en) 2014-06-12 2016-12-31 Ra Pharmaceuticals Inc Modulation of complement activity
HUE056613T2 (hu) 2015-01-28 2022-02-28 Ra Pharmaceuticals Inc Komplementaktivitás modulátorai
EP3340983B1 (en) 2015-08-26 2023-10-04 Achillion Pharmaceuticals, Inc. Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders
WO2017035405A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amino compounds for treatment of immune and inflammatory disorders
WO2017035401A1 (en) 2015-08-26 2017-03-02 Achillion Pharmaceuticals, Inc. Amide compounds for treatment of immune and inflammatory disorders
AR106018A1 (es) 2015-08-26 2017-12-06 Achillion Pharmaceuticals Inc Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos
KR20180094913A (ko) 2015-12-16 2018-08-24 라 파마슈티컬스 인코포레이티드 보체 활성의 조절인자
MX2019006527A (es) 2016-12-07 2019-08-01 Ra Pharmaceuticals Inc Moduladores de la actividad del complemento.
EP3985002B1 (en) 2017-03-01 2025-05-07 Achillion Pharmaceuticals, Inc. Aryl, heteroaryl, and heterocyclic pharmaceutical compounds for treatment of medical disorders
WO2018160891A1 (en) 2017-03-01 2018-09-07 Achillion Pharmaceutical, Inc. Pharmaceutical compounds for treatment of medical disorders
WO2019028284A1 (en) 2017-08-02 2019-02-07 Achillion Pharmaceuticals, Inc. THERAPEUTIC REGIMES FOR THE TREATMENT OF NOCTURNAL PAROXYSTIC HEMOGLOBINURIA
JP2021505565A (ja) 2017-12-04 2021-02-18 ラ ファーマシューティカルズ インコーポレイテッドRa Pharmaceuticals,Inc. 補体活性のモジュレータ
JP2021507884A (ja) * 2017-12-15 2021-02-25 アペリス・ファーマシューティカルズ・インコーポレイテッドApellis Pharmaceuticals,Inc. 投与レジメンならびに関連組成物および方法
AU2019247467B2 (en) 2018-04-06 2023-01-19 The Trustees Of The University Of Pennsylvania Compstatin analogs with increased solubility and improved pharmacokinetic properties
US11814363B2 (en) 2018-09-06 2023-11-14 Achillion Pharmaceuticals, Inc. Morphic forms of danicopan
JP7443375B2 (ja) 2018-09-06 2024-03-05 アキリオン ファーマシューティカルズ, インコーポレーテッド 医学的障害の治療のための大環状化合物
KR20210093855A (ko) 2018-09-25 2021-07-28 아칠리온 파르마세우티칼스 인코포레이티드 보체 인자 d 억제제의 형태체 형태
JP7471300B2 (ja) 2018-12-17 2024-04-19 アキリオン ファーマシューティカルズ, インコーポレーテッド 補体介在性疾患を治療するための的を絞った投与
JP2022524078A (ja) 2019-03-08 2022-04-27 ラ ファーマシューティカルズ インコーポレイテッド 深部組織浸透性c5阻害剤としてのジルコプラン
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AU2020261059A1 (en) 2019-04-24 2021-10-14 Ra Pharmaceuticals, Inc. Compositions and methods for modulating complement activity

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US20130344082A1 (en) 2013-12-26
WO2013192319A1 (en) 2013-12-27
IN2015DN00438A (en, 2012) 2015-06-19
CA2877299C (en) 2022-07-12
AU2013277217B2 (en) 2018-03-08
EP2863949A1 (en) 2015-04-29
US9579360B2 (en) 2017-02-28
AU2013277217A2 (en) 2015-01-22
US20170202935A1 (en) 2017-07-20
CA2877299A1 (en) 2013-12-27
JP2015523999A (ja) 2015-08-20
AU2013277217A1 (en) 2015-01-22
EP2863949A4 (en) 2016-03-02
US10668135B2 (en) 2020-06-02
CN104640567A (zh) 2015-05-20
EP2863949B1 (en) 2019-01-23

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