CA2877299C - Methods of treating or preventing periodontitis and diseases associated with periodontitis - Google Patents
Methods of treating or preventing periodontitis and diseases associated with periodontitis Download PDFInfo
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- CA2877299C CA2877299C CA2877299A CA2877299A CA2877299C CA 2877299 C CA2877299 C CA 2877299C CA 2877299 A CA2877299 A CA 2877299A CA 2877299 A CA2877299 A CA 2877299A CA 2877299 C CA2877299 C CA 2877299C
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| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| EP3623367B1 (en) | 2014-02-25 | 2022-09-28 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of complement mediated disorders |
| HRP20191763T1 (hr) | 2014-06-12 | 2019-12-27 | Ra Pharmaceuticals, Inc. | Modulacija komplementarne aktivnosti |
| PL3250230T3 (pl) | 2015-01-28 | 2022-02-14 | Ra Pharmaceuticals, Inc. | Modulatory aktywności dopełniacza |
| EP3340983B1 (en) | 2015-08-26 | 2023-10-04 | Achillion Pharmaceuticals, Inc. | Aryl, heteroaryl, and heterocyclic compounds for treatment of immune and inflammatory disorders |
| AR106018A1 (es) | 2015-08-26 | 2017-12-06 | Achillion Pharmaceuticals Inc | Compuestos de arilo, heteroarilo y heterocíclicos para el tratamiento de trastornos médicos |
| WO2017035401A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amide compounds for treatment of immune and inflammatory disorders |
| WO2017035405A1 (en) | 2015-08-26 | 2017-03-02 | Achillion Pharmaceuticals, Inc. | Amino compounds for treatment of immune and inflammatory disorders |
| PT3685847T (pt) | 2015-12-16 | 2023-03-14 | Ra Pharmaceuticals Inc | Moduladores de atividade de complemento |
| US11123399B2 (en) | 2016-12-07 | 2021-09-21 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| WO2018160891A1 (en) | 2017-03-01 | 2018-09-07 | Achillion Pharmaceutical, Inc. | Pharmaceutical compounds for treatment of medical disorders |
| KR20240019857A (ko) | 2017-03-01 | 2024-02-14 | 아칠리온 파르마세우티칼스 인코포레이티드 | 의학적 장애의 치료를 위한 아릴, 헤테로아릴, 및 헤테로사이클릭 약학적 화합물 |
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| CA3084043A1 (en) | 2017-12-04 | 2019-06-13 | Ra Pharmaceuticals, Inc. | Modulators of complement activity |
| AU2018386304B2 (en) | 2017-12-15 | 2023-12-07 | Apellis Pharmaceuticals, Inc. | Dosing regimens and related compositions and methods |
| JP7423070B2 (ja) | 2018-04-06 | 2024-01-29 | ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア | 増加した溶解度および改善された薬物動態特性を有するコンプスタチンアナログ |
| WO2020051538A1 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Morphic forms of complement factor d inhibitors |
| WO2020051532A2 (en) | 2018-09-06 | 2020-03-12 | Achillion Pharmaceuticals, Inc. | Macrocyclic compounds for the treatment of medical disorders |
| MX2021003425A (es) | 2018-09-25 | 2021-07-16 | Achillion Pharmaceuticals Inc | Formas morficas de los inhibidores del factor d del complemento. |
| CN113195472A (zh) | 2018-12-17 | 2021-07-30 | 艾其林医药公司 | 用于治疗补体介导的病症的靶向给药 |
| JP2022524078A (ja) | 2019-03-08 | 2022-04-27 | ラ ファーマシューティカルズ インコーポレイテッド | 深部組織浸透性ｃ５阻害剤としてのジルコプラン |
| EP3947352A1 (en) | 2019-03-29 | 2022-02-09 | RA Pharmaceuticals, Inc. | Complement modulators and related methods |
| WO2020219822A1 (en) | 2019-04-24 | 2020-10-29 | Ra Pharmaceuticals, Inc. | Compositions and methods for modulating complement activity |
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| US5270365A (en) | 1991-12-17 | 1993-12-14 | Merck & Co., Inc. | Prevention and treatment of periodontal disease with alendronate |
| US5627264A (en) * | 1994-03-03 | 1997-05-06 | Alexion Pharmaceuticals, Inc. | Chimeric complement inhibitor proteins |
| JP2001294536A (ja) * | 2000-04-12 | 2001-10-23 | Sunstar Inc | 歯周病予防・治療剤 |
| US20050169921A1 (en) * | 2004-02-03 | 2005-08-04 | Leonard Bell | Method of treating hemolytic disease |
| SI1928454T1 (sl) * | 2005-05-10 | 2015-01-30 | Intermune, Inc. | Piridonski derivati za moduliranje s stresom aktiviranega protein kinaznega sistema |
| HUE026001T2 (en) * | 2007-02-05 | 2016-04-28 | Apellis Pharmaceuticals Inc | Compstatin analogues for use in the treatment of the inflammatory condition of the respiratory system |
| WO2010056399A1 (en) * | 2008-11-17 | 2010-05-20 | Incode Biopharmaceutics, Inc. | Method and composition for modulating the immune system and various inflammatory conditions comprising complement depletors |
| US8946145B2 (en) * | 2009-05-01 | 2015-02-03 | The Trustees Of The University Of Pennsylvania | Modified compstatin with peptide backbone and C-terminal modifications |
| WO2010132954A1 (en) | 2009-05-21 | 2010-11-25 | Oral Health Australia Pty Ltd | Method of treating periodontal disease by administering antagonists of par-2 |
| CA2774008C (en) * | 2009-09-23 | 2017-06-20 | The Regents Of The University Of Colorado, A Body Corporate | Toll-like receptor modulators and uses thereof |
| AU2011207441A1 (en) | 2010-01-22 | 2012-08-09 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
| EP2548888B1 (en) * | 2010-03-17 | 2017-11-01 | Kagoshima University | Periodontal-disease-specific peptide, and treatment and diagnosis of periodontal disease using same |
| EP2723361B1 (en) * | 2011-06-22 | 2019-10-30 | Apellis Pharmaceuticals, Inc. | Methods of treating chronic disorders with complement inhibitors |
| HUE047375T2 (hu) * | 2011-09-07 | 2020-04-28 | Univ Pennsylvania | Javított farmakokinetikai tulajdonságokkal rendelkezõ compstatin analógok |
| US9579360B2 (en) * | 2012-06-20 | 2017-02-28 | The Trustees Of The University Of Pennsylvania | Methods of treating or preventing periodontitis and diseases associated with periodontitis |
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| EP2863949B1 (en) | 2019-01-23 |
| US10668135B2 (en) | 2020-06-02 |
| JP2015523999A (ja) | 2015-08-20 |
| AU2013277217A2 (en) | 2015-01-22 |
| CA2877299A1 (en) | 2013-12-27 |
| US20130344082A1 (en) | 2013-12-26 |
| EP2863949A1 (en) | 2015-04-29 |
| WO2013192319A1 (en) | 2013-12-27 |
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