JP6338955B2 - 細胞培養装置および画像解析装置 - Google Patents

細胞培養装置および画像解析装置 Download PDF

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JP6338955B2
JP6338955B2 JP2014147870A JP2014147870A JP6338955B2 JP 6338955 B2 JP6338955 B2 JP 6338955B2 JP 2014147870 A JP2014147870 A JP 2014147870A JP 2014147870 A JP2014147870 A JP 2014147870A JP 6338955 B2 JP6338955 B2 JP 6338955B2
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cells
cell
analysis
light
image
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JP2016021915A5 (enExample
JP2016021915A (ja
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直子 千田
直子 千田
賢太郎 大澤
賢太郎 大澤
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Hitachi High Tech Corp
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Priority to US15/325,670 priority patent/US10717962B2/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/46Means for regulation, monitoring, measurement or control, e.g. flow regulation of cellular or enzymatic activity or functionality, e.g. cell viability
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2223/00Investigating materials by wave or particle radiation
    • G01N2223/40Imaging

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Organic Chemistry (AREA)
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  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Computer Hardware Design (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2014147870A 2014-07-18 2014-07-18 細胞培養装置および画像解析装置 Active JP6338955B2 (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2014147870A JP6338955B2 (ja) 2014-07-18 2014-07-18 細胞培養装置および画像解析装置
PCT/JP2015/067915 WO2016009789A1 (ja) 2014-07-18 2015-06-22 細胞培養装置および画像解析装置
US15/325,670 US10717962B2 (en) 2014-07-18 2015-06-22 Cell culture device and image analysis device
US16/899,939 US20200308530A1 (en) 2014-07-18 2020-06-12 Cell culture device and image analysis device

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JP2014147870A JP6338955B2 (ja) 2014-07-18 2014-07-18 細胞培養装置および画像解析装置

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JP2016021915A JP2016021915A (ja) 2016-02-08
JP2016021915A5 JP2016021915A5 (enExample) 2017-04-27
JP6338955B2 true JP6338955B2 (ja) 2018-06-06

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Families Citing this family (11)

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Publication number Priority date Publication date Assignee Title
US10846849B2 (en) 2016-06-16 2020-11-24 Hitachi High-Tech Corporation Method for analyzing state of cells in spheroid
JP6580012B2 (ja) 2016-09-28 2019-09-25 富士フイルム株式会社 撮影画像評価装置および方法並びにプログラム
JP2018174864A (ja) * 2017-04-19 2018-11-15 アズビル株式会社 細胞生存率判定装置及び細胞生存率判定方法
JP7030423B2 (ja) * 2017-04-27 2022-03-07 シスメックス株式会社 画像解析方法、装置、プログラムおよび深層学習アルゴリズムの製造方法
WO2019234878A1 (ja) * 2018-06-07 2019-12-12 オリンパス株式会社 画像処理装置および培養評価システム
WO2020003454A1 (ja) 2018-06-28 2020-01-02 株式会社ニコン 装置、システム及びプログラム
KR102058826B1 (ko) * 2019-08-26 2019-12-23 한국광기술원 세포 배양 장치와 이를 이용한 세포 배양 모니터링 시스템 및 방법
JP7650240B2 (ja) 2019-09-30 2025-03-24 テルモ株式会社 シート状細胞培養物調製用デバイス
JP2023018274A (ja) * 2021-07-27 2023-02-08 株式会社エビデント 積層化細胞シートの作製支援装置、作製支援システム、作製支援方法、及び、プログラム
EP4419643A1 (en) * 2021-10-21 2024-08-28 Chromologic LLC Monitoring objects in aqueous media using optical coherence tomography
JPWO2023153414A1 (enExample) * 2022-02-08 2023-08-17

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Publication number Priority date Publication date Assignee Title
ATE268901T1 (de) * 1999-01-29 2004-06-15 June Iris Medford Optisches kohärenzmikroskop und verfahren zur schnellen 3d-in-vivo -visualisierung biologischer funktionen
JP4689171B2 (ja) * 2004-02-06 2011-05-25 オリンパス株式会社 培養細胞の状態計測方法及び計測装置
JP4409332B2 (ja) * 2004-03-30 2010-02-03 株式会社トプコン 光画像計測装置
JP4852890B2 (ja) 2005-05-31 2012-01-11 株式会社ニコン 細胞の自動良否判定システム
JP5523664B2 (ja) * 2007-11-06 2014-06-18 株式会社ミツトヨ 干渉計
WO2011016189A1 (ja) * 2009-08-07 2011-02-10 株式会社ニコン 細胞の分類手法、この手法を用いた画像処理プログラム及び画像処理装置、並びに細胞塊の製造方法
JP2011078447A (ja) * 2009-10-02 2011-04-21 Fujifilm Corp 光構造観察装置、その構造情報処理方法及び光構造観察装置を備えた内視鏡装置
US20140072599A1 (en) 2011-02-28 2014-03-13 Osaka University Cytokine-producing cell sheet and method for using the same
JP5802751B2 (ja) * 2011-06-27 2015-11-04 株式会社日立製作所 細胞培養装置および細胞培養方法
JP5891719B2 (ja) 2011-11-08 2016-03-23 大日本印刷株式会社 細胞断面解析装置、細胞断面解析方法、及び細胞断面解析プログラム
JP5991368B2 (ja) * 2012-03-16 2016-09-14 株式会社日立製作所 細胞シート、細胞培養方法および細胞培養装置
WO2014002271A1 (ja) * 2012-06-29 2014-01-03 株式会社日立製作所 細胞組織検査システム、細胞培養装置、及び細胞組織検査方法

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US10717962B2 (en) 2020-07-21
US20200308530A1 (en) 2020-10-01
US20170159004A1 (en) 2017-06-08
WO2016009789A1 (ja) 2016-01-21
JP2016021915A (ja) 2016-02-08

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