JP6312718B2 - デフェラシロクスを調製するための方法 - Google Patents

デフェラシロクスを調製するための方法 Download PDF

Info

Publication number
JP6312718B2
JP6312718B2 JP2015560831A JP2015560831A JP6312718B2 JP 6312718 B2 JP6312718 B2 JP 6312718B2 JP 2015560831 A JP2015560831 A JP 2015560831A JP 2015560831 A JP2015560831 A JP 2015560831A JP 6312718 B2 JP6312718 B2 JP 6312718B2
Authority
JP
Japan
Prior art keywords
formula
deferasirox
solvent
hydroxyphenyl
precipitate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2015560831A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016515103A (ja
Inventor
クマール，コタコンダ，キラン
ダモダール，レッディー，ギアル
プレッラ，ベンカータ，シュリニバース
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biocon Ltd
Original Assignee
Biocon Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocon Ltd filed Critical Biocon Ltd
Priority claimed from PCT/IB2014/059456 external-priority patent/WO2014136062A2/en
Publication of JP2016515103A publication Critical patent/JP2016515103A/ja
Application granted granted Critical
Publication of JP6312718B2 publication Critical patent/JP6312718B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2015560831A 2013-03-06 2014-03-05 デフェラシロクスを調製するための方法 Active JP6312718B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN975/CHE/2013 2013-03-06
IN975CH2013 2013-03-06
PCT/IB2014/059456 WO2014136062A2 (en) 2013-03-06 2014-03-05 Process for the preparation of deferasirox

Publications (2)

Publication Number Publication Date
JP2016515103A JP2016515103A (ja) 2016-05-26
JP6312718B2 true JP6312718B2 (ja) 2018-04-18

Family

ID=54198664

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015560831A Active JP6312718B2 (ja) 2013-03-06 2014-03-05 デフェラシロクスを調製するための方法

Country Status (11)

Country Link
US (1) US9593086B2 (enExample)
EP (1) EP2964659B1 (enExample)
JP (1) JP6312718B2 (enExample)
KR (1) KR102282372B1 (enExample)
AU (1) AU2014224252B2 (enExample)
CA (1) CA2903712C (enExample)
DK (1) DK2964659T3 (enExample)
ES (1) ES2650118T3 (enExample)
NO (1) NO2964659T3 (enExample)
PL (1) PL2964659T3 (enExample)
RU (1) RU2659034C2 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11022880B2 (en) * 2017-10-25 2021-06-01 Tokyo Ohka Kogyo Co., Ltd. Chemically amplified positive-type photosensitive resin composition, photosensitive dry film, method of manufacturing photosensitive dry film, method of manufacturing patterned resist film, method of manufacturing substrate with template, method of manufacturing plated article, and mercapto compound

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH478827A (de) * 1967-02-27 1969-09-30 Geigy Ag J R Verfahren zur Herstellung von Areno-oxazinonverbindungen
MY129541A (en) * 1996-06-25 2007-04-30 Novartis Ag Substituded 3,5-diphenyl-1,2,4-triazoles and their use as pharmaceutical metal chelators
EP2291360A2 (en) * 2008-04-21 2011-03-09 Actavis Group PTC ehf. Solid state forms of deferasirox salts and process for the preparation thereof
WO2009147529A1 (en) * 2008-06-02 2009-12-10 Actavis Group Ptc Ehf Substantially pure deferasirox and processes for the preparation thereof
WO2010023685A2 (en) * 2008-08-29 2010-03-04 Matrix Laboratories Limited Crystalline form of 2-(2-hydroxy phenyl)benz[e][1,3]oxazin-4-one, process for the same and use for producing 4-(3,5-bis(2-hydroxyphenyl)-1h-1,2,4-triazol-1-yl)benzoic acid
WO2011021218A2 (en) * 2009-08-12 2011-02-24 Msn Laboratories Limited Process for the preparation of 4-[3,5-bis(2-hydroxyphenyl)-1h-1,2,4-triazol-1-yl]-benzoic acid and its amine salts
BR112012013710A2 (pt) * 2009-12-07 2015-09-15 Mapi Pharma Ltd processos para a preparação de deferasirox e polimorfos de deferasirox.
WO2012025935A2 (en) * 2010-08-25 2012-03-01 Ramamohan Rao Davuluri A process for the preparation of 2-(2-hydroxyphenyl)-benz[1,3]oxazin-4-one and its use for preparation of 4-[3, 5-bis (2-hydroxyphenyl)-1h-1, 2, 4-triazol-1-yl] benzoic acid
JP2012126882A (ja) * 2010-11-22 2012-07-05 Fujifilm Corp 紫外線吸収剤組成物
EP2643306B1 (en) * 2010-11-24 2015-09-23 Alembic Pharmaceuticals Limited Process for the preparation of deferasirox
ITMI20110543A1 (it) * 2011-04-01 2012-10-02 Erregierre Spa Processo per la produzione di deferasirox

Also Published As

Publication number Publication date
CA2903712A1 (en) 2014-09-12
CA2903712C (en) 2022-06-14
RU2015139499A (ru) 2017-04-10
AU2014224252B2 (en) 2016-09-22
JP2016515103A (ja) 2016-05-26
KR20150123934A (ko) 2015-11-04
EP2964659B1 (en) 2017-08-09
PL2964659T3 (pl) 2018-04-30
US9593086B2 (en) 2017-03-14
EP2964659A2 (en) 2016-01-13
RU2659034C2 (ru) 2018-06-27
DK2964659T3 (da) 2017-11-27
AU2014224252A1 (en) 2015-09-24
EP2964659A4 (en) 2016-11-02
NO2964659T3 (enExample) 2018-01-06
KR102282372B1 (ko) 2021-07-27
US20160024025A1 (en) 2016-01-28
ES2650118T3 (es) 2018-01-17

Similar Documents

Publication Publication Date Title
US20100076196A1 (en) Process for the preparation of iloperidone
CN107207538A (zh) 制备cenicriviroc及相关类似物的方法
US6515128B2 (en) Processes for preparing cilostazol
JP3845059B2 (ja) シロスタゾールの製造方法
WO2006021974A1 (en) A process for synthesizing diol (viii)-an intermediate of montelukast sodium
EP2643306B1 (en) Process for the preparation of deferasirox
WO2012131017A1 (en) Process for the production of deferasirox
JP2016515103A (ja) デフェラシロクスを調製するための方法
WO2014136062A2 (en) Process for the preparation of deferasirox
CN109485567B (zh) 一种4-羟甲基噻唑的清洁制备方法及其中间体
US7078543B2 (en) Methods for producing oxirane carboxylic acids and derivatives thereof
JP3523874B2 (ja) 中間体としてのキノロン二硫化物
JP2976493B2 (ja) 塩素化ピラゾールカルボン酸誘導体の製造方法
JP4794078B2 (ja) 新規な１，１，３，３−テトラフルオロ−１，３−ジヒドロイソベンゾフラン化合物及びそれらの製造方法
CN101356158A (zh) 用于制备孟鲁司特的新中间体及相关的化合物
JP2004244362A (ja) １，２−ジ置換−１，４−ジヒドロ−オキソキノリン誘導体の製造方法
JPH07330697A (ja) 置換インダン誘導体の製造法
JPH0236164A (ja) ２‐ニトロ‐５‐（置換アリールオキシ）ベンゾヒドロキシム酸誘導体の製造法
JP2003055375A (ja) 光学活性ヒドラジン化合物の製造法
JPH0474353B2 (enExample)
UA101946C2 (uk) Спосіб та інтермедіати для одержання інгібіторів інтегрази
JPH07278104A (ja) ５−アセトキシメチルピロール−２−カルボン酸誘導体の製造方法
WO2011121091A1 (en) Efficient synthesis for the preparation of montelukast and novel crystalline form of intermediates therein
JPS6377849A (ja) 置換アミド誘導体の製造方法
KR20050108739A (ko) E형의 2-벤조일-3-디메틸아미노아크릴레이트 유도체의 제조방법

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20170209

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20171129

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20171130

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20180209

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20180223

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20180320

R150 Certificate of patent or registration of utility model

Ref document number: 6312718

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250