JP6297490B2 - 診断マーカー - Google Patents

診断マーカー Download PDF

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Publication number
JP6297490B2
JP6297490B2 JP2014528597A JP2014528597A JP6297490B2 JP 6297490 B2 JP6297490 B2 JP 6297490B2 JP 2014528597 A JP2014528597 A JP 2014528597A JP 2014528597 A JP2014528597 A JP 2014528597A JP 6297490 B2 JP6297490 B2 JP 6297490B2
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JP
Japan
Prior art keywords
methylation
erbb2 gene
cancer
erbb2
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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JP2014528597A
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English (en)
Japanese (ja)
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JP2014525270A (ja
JP2014525270A5 (enExample
Inventor
デーヴィッド シャムズ，
デーヴィッド シャムズ，
トーマス イー． ジャヌアーリオ，
トーマス イー． ジャヌアーリオ，
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Genentech Inc
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Genentech Inc
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46826936&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JP6297490(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of JP2014525270A publication Critical patent/JP2014525270A/ja
Publication of JP2014525270A5 publication Critical patent/JP2014525270A5/ja
Application granted granted Critical
Publication of JP6297490B2 publication Critical patent/JP6297490B2/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2014528597A 2011-08-31 2012-08-30 診断マーカー Expired - Fee Related JP6297490B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161529917P 2011-08-31 2011-08-31
US61/529,917 2011-08-31
PCT/US2012/053114 WO2013033380A1 (en) 2011-08-31 2012-08-30 Diagnostic markers

Publications (3)

Publication Number Publication Date
JP2014525270A JP2014525270A (ja) 2014-09-29
JP2014525270A5 JP2014525270A5 (enExample) 2015-03-05
JP6297490B2 true JP6297490B2 (ja) 2018-03-20

Family

ID=46826936

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014528597A Expired - Fee Related JP6297490B2 (ja) 2011-08-31 2012-08-30 診断マーカー

Country Status (13)

Country Link
US (4) US20130084286A1 (enExample)
EP (1) EP2751285B2 (enExample)
JP (1) JP6297490B2 (enExample)
KR (1) KR20140057356A (enExample)
CN (1) CN104024432B (enExample)
AU (1) AU2012301889B2 (enExample)
BR (1) BR112014004762A2 (enExample)
CA (1) CA2845179A1 (enExample)
IL (1) IL230851A0 (enExample)
MX (1) MX2014002436A (enExample)
RU (1) RU2614254C2 (enExample)
SG (1) SG2014011316A (enExample)
WO (1) WO2013033380A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9984201B2 (en) 2015-01-18 2018-05-29 Youhealth Biotech, Limited Method and system for determining cancer status
JP6876304B2 (ja) * 2016-06-10 2021-05-26 国立研究開発法人国立がん研究センター 癌に対する薬物療法の効果の予測方法
EP3481403B1 (en) 2016-07-06 2022-02-09 Youhealth Biotech, Limited Solid tumor methylation markers and uses thereof
US10513739B2 (en) 2017-03-02 2019-12-24 Youhealth Oncotech, Limited Methylation markers for diagnosing hepatocellular carcinoma and lung cancer
CN110511997A (zh) 2018-05-22 2019-11-29 广州市康立明生物科技有限责任公司 肿瘤标志物、甲基化试剂、试剂盒及其应用

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Also Published As

Publication number Publication date
AU2012301889A1 (en) 2014-03-06
EP2751285A1 (en) 2014-07-09
KR20140057356A (ko) 2014-05-12
CN104024432B (zh) 2017-02-22
CN104024432A (zh) 2014-09-03
WO2013033380A1 (en) 2013-03-07
RU2614254C2 (ru) 2017-03-24
US20200024670A1 (en) 2020-01-23
US20150086543A1 (en) 2015-03-26
JP2014525270A (ja) 2014-09-29
HK1199475A1 (en) 2015-07-03
CA2845179A1 (en) 2013-03-07
US20170306419A1 (en) 2017-10-26
US20130084286A1 (en) 2013-04-04
EP2751285B2 (en) 2020-04-01
SG2014011316A (en) 2014-06-27
RU2014110895A (ru) 2015-10-10
IL230851A0 (en) 2014-03-31
AU2012301889B2 (en) 2016-04-21
US11261498B2 (en) 2022-03-01
BR112014004762A2 (pt) 2018-06-19
MX2014002436A (es) 2014-05-27
EP2751285B1 (en) 2017-03-01

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