JP6289460B2 - 難聴を治療するためのニコチンアミドリボシド - Google Patents
難聴を治療するためのニコチンアミドリボシド Download PDFInfo
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- JP6289460B2 JP6289460B2 JP2015523158A JP2015523158A JP6289460B2 JP 6289460 B2 JP6289460 B2 JP 6289460B2 JP 2015523158 A JP2015523158 A JP 2015523158A JP 2015523158 A JP2015523158 A JP 2015523158A JP 6289460 B2 JP6289460 B2 JP 6289460B2
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- hearing loss
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- nicotinamide riboside
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- Pathology (AREA)
- Neurosurgery (AREA)
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- Biotechnology (AREA)
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- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
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- Biochemistry (AREA)
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Applications Claiming Priority (3)
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| US201261672169P | 2012-07-16 | 2012-07-16 | |
| US61/672,169 | 2012-07-16 | ||
| PCT/US2013/050511 WO2014014828A1 (en) | 2012-07-16 | 2013-07-15 | Nicotinamide riboside to treat hearing loss |
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| JP2015524408A JP2015524408A (ja) | 2015-08-24 |
| JP2015524408A5 JP2015524408A5 (enExample) | 2016-09-08 |
| JP6289460B2 true JP6289460B2 (ja) | 2018-03-07 |
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| EP (1) | EP2872128B1 (enExample) |
| JP (1) | JP6289460B2 (enExample) |
| ES (1) | ES2785303T3 (enExample) |
| WO (1) | WO2014014828A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2007061798A2 (en) | 2005-11-18 | 2007-05-31 | Cornell Research Foundation, Inc. | Nicotinoyl riboside compositions and methods of use |
| RU2016149767A (ru) | 2014-06-06 | 2018-07-16 | Глэксосмитклайн Интеллекчуал Проперти (Но.2) Лимитед | Аналоги никотинамидрибозида и фармацевтические композиции и их применение |
| CA2956163C (en) | 2014-07-24 | 2023-01-10 | W.R. Grace & Co.-Conn. | Crystalline form of nicotinamide riboside |
| ES2963057T3 (es) | 2015-03-09 | 2024-03-25 | Grace W R & Co | Forma cristalina de ribósido de nicotinamida |
| SI3297628T1 (sl) | 2015-05-18 | 2021-10-29 | Sensorion | Azasetron za uporabo pri zdravljenju izgube sluha |
| WO2017011788A1 (en) | 2015-07-15 | 2017-01-19 | Cornell University | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives |
| US9855289B2 (en) | 2015-08-05 | 2018-01-02 | Metro International Biotech, Llc | Nicotinamide mononucleotide derivatives and their uses |
| GB2542881B (en) | 2015-10-02 | 2020-01-01 | Carr Andrew | Crystal forms of ß-nicotinamide mononucleotide |
| HRP20240453T1 (hr) | 2016-04-14 | 2024-06-21 | Sensorion | (+)-azasetron za uporabu u liječenju poremećaja uha |
| US10576125B2 (en) | 2016-10-31 | 2020-03-03 | Hough Ear Institute | Methods for enhancing synaptogenesis and neuritogenesis |
| NZ803738A (en) | 2016-11-11 | 2024-05-31 | Chromadex Inc | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof |
| EP3554285A4 (en) | 2016-11-29 | 2021-01-20 | University of Iowa Research Foundation | USE OF NAD PRECURSORS TO IMPROVE THE HEALTH OF MOTHER AND / OR OFFspring |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| US20190328761A1 (en) | 2016-12-21 | 2019-10-31 | Newsouth Innovations Pty Limited | Methods for enhancing vascular density |
| AU2018250242B2 (en) | 2017-04-05 | 2021-07-15 | Cornell University | Beta-nicotinate ester nucleotides and processes for preparing same |
| EP3727400A4 (en) | 2017-12-22 | 2021-10-20 | Elysium Health, Inc. | CRYSTALLINE FORMS OF NICOTINAMIDE RIBOSIDE CHLORIDE |
| WO2019152416A1 (en) | 2018-01-30 | 2019-08-08 | Metro International Biotech, Llc | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof |
| US11939348B2 (en) | 2019-03-22 | 2024-03-26 | Metro International Biotech, Llc | Compositions comprising a phosphorus derivative of nicotinamide riboside and methods for modulation of nicotinamide adenine dinucleotide |
| US10618927B1 (en) | 2019-03-22 | 2020-04-14 | Metro International Biotech, Llc | Compositions and methods for modulation of nicotinamide adenine dinucleotide |
| JP7675061B2 (ja) | 2019-07-19 | 2025-05-12 | バイオシント アクチェンゲゼルシャフト | ニコチンアミドリボフラノシド塩の製造方法、ニコチンアミドリボフラノシド塩自体、およびその使用 |
| CA3219033A1 (en) | 2021-05-27 | 2022-12-01 | Metro International Biotech, Llc | Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of making and use |
| EP4727544A2 (en) | 2023-06-14 | 2026-04-22 | Chromadex Inc. | Nicotinamide riboside and derivatives thereof in intravenous formulations and methods of use thereof |
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| CH695593A5 (de) | 2002-12-17 | 2006-06-30 | Granite Trading Ltd | Vorsatzlinse. |
| US20060063802A1 (en) | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| AU2006269459B2 (en) | 2005-07-07 | 2013-02-07 | Sirtris Pharmaceuticals, Inc. | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| WO2009132050A2 (en) * | 2008-04-21 | 2009-10-29 | Otonomy, Inc. | Auris formulations for treating otic diseases and conditions |
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- 2013-07-15 ES ES13820653T patent/ES2785303T3/es active Active
- 2013-07-15 US US14/414,924 patent/US9861651B2/en active Active
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| US9861651B2 (en) | 2018-01-09 |
| EP2872128B1 (en) | 2020-02-19 |
| JP2015524408A (ja) | 2015-08-24 |
| WO2014014828A1 (en) | 2014-01-23 |
| EP2872128A4 (en) | 2016-03-30 |
| US20150174148A1 (en) | 2015-06-25 |
| EP2872128A1 (en) | 2015-05-20 |
| ES2785303T3 (es) | 2020-10-06 |
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