JP6289460B2 - 難聴を治療するためのニコチンアミドリボシド - Google Patents
難聴を治療するためのニコチンアミドリボシド Download PDFInfo
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- JP6289460B2 JP6289460B2 JP2015523158A JP2015523158A JP6289460B2 JP 6289460 B2 JP6289460 B2 JP 6289460B2 JP 2015523158 A JP2015523158 A JP 2015523158A JP 2015523158 A JP2015523158 A JP 2015523158A JP 6289460 B2 JP6289460 B2 JP 6289460B2
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- hearing loss
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- nicotinamide riboside
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Applications Claiming Priority (3)
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| US201261672169P | 2012-07-16 | 2012-07-16 | |
| US61/672,169 | 2012-07-16 | ||
| PCT/US2013/050511 WO2014014828A1 (en) | 2012-07-16 | 2013-07-15 | Nicotinamide riboside to treat hearing loss |
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| JP2015524408A JP2015524408A (ja) | 2015-08-24 |
| JP2015524408A5 JP2015524408A5 (enExample) | 2016-09-08 |
| JP6289460B2 true JP6289460B2 (ja) | 2018-03-07 |
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| WO (1) | WO2014014828A1 (enExample) |
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| DK1957086T3 (en) | 2005-11-18 | 2018-06-06 | Cornell Res Foundation Inc | NICOTINOYL RIBOSIDE COMPOSITIONS AND METHODS OF USE |
| BR112016028672A2 (pt) | 2014-06-06 | 2017-08-22 | Glaxosmithkline Ip No 2 Ltd | análogos de ribosídeo de nicotinamida e composições farmacêuticas e usos do mesmo |
| EP3174891B1 (en) | 2014-07-24 | 2020-01-29 | W.R. Grace & CO. - CONN. | Crystalline form of nicotinamide riboside |
| BR112017019409A2 (pt) | 2015-03-09 | 2018-04-24 | Grace W R & Co | forma cristalina de ribosídeo de nicotinamida |
| PL3297628T3 (pl) | 2015-05-18 | 2021-12-06 | Sensorion | Azasetron do stosowania w leczeniu niedosłuchu |
| EP3322419B1 (en) | 2015-07-15 | 2025-09-03 | Cornell University | Syntheses, activities, and methods of use of dihydronicotinamide riboside derivatives |
| MX2018001363A (es) | 2015-08-05 | 2018-11-29 | Metro Int Biotech Llc | Derivados del mononucleotido de nicotinamida y sus usos. |
| GB2542881B (en) | 2015-10-02 | 2020-01-01 | Carr Andrew | Crystal forms of ß-nicotinamide mononucleotide |
| HRP20240453T1 (hr) * | 2016-04-14 | 2024-06-21 | Sensorion | (+)-azasetron za uporabu u liječenju poremećaja uha |
| CN110248650A (zh) * | 2016-10-31 | 2019-09-17 | 霍夫耳科研究所 | 用于增强突触发生和神经突发生的方法 |
| US10689411B2 (en) | 2016-11-11 | 2020-06-23 | The Queen's University Of Belfast | Efficient and scalable syntheses of nicotinoyl ribosides and reduced nicotinoyl ribosides, modified derivatives thereof, phosphorylated analogs thereof, adenylyl dinucleotide conjugates thereof, and novel crystalline forms thereof |
| US11071747B2 (en) | 2016-11-29 | 2021-07-27 | University Of Iowa Research Foundation | Use of NAD precursors for breast enhancement |
| MX2019006278A (es) | 2016-11-29 | 2019-08-21 | Univ Iowa Res Found | Uso de precursores de nad para mejorar la salud materna y/o salud de la descendencia. |
| EP3606929B1 (en) | 2017-04-05 | 2021-06-02 | Cornell University | Beta-nicotinate ester nucleotides and processes for preparing same |
| CN112020363A (zh) | 2017-12-22 | 2020-12-01 | 益力舒健康公司 | 烟酰胺核苷氯化物的结晶形式 |
| WO2019152416A1 (en) | 2018-01-30 | 2019-08-08 | Metro International Biotech, Llc | Nicotinamide riboside analogs, pharmaceutical compositions, and uses thereof |
| US10618927B1 (en) | 2019-03-22 | 2020-04-14 | Metro International Biotech, Llc | Compositions and methods for modulation of nicotinamide adenine dinucleotide |
| US11939348B2 (en) | 2019-03-22 | 2024-03-26 | Metro International Biotech, Llc | Compositions comprising a phosphorus derivative of nicotinamide riboside and methods for modulation of nicotinamide adenine dinucleotide |
| CN114423771A (zh) | 2019-07-19 | 2022-04-29 | 生物合成股份公司 | 制备烟酰胺呋喃核糖苷盐的方法、烟酰胺呋喃核糖苷盐本身及其用途 |
| WO2022251491A1 (en) | 2021-05-27 | 2022-12-01 | Metro International Biotech, Llc | Crystalline solids of nicotinic acid mononucleotide and esters thereof and methods of making and use |
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| CH695593A5 (de) | 2002-12-17 | 2006-06-30 | Granite Trading Ltd | Vorsatzlinse. |
| US20060063802A1 (en) | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| US20070149466A1 (en) * | 2005-07-07 | 2007-06-28 | Michael Milburn | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| CA2613141A1 (en) | 2005-07-07 | 2007-01-18 | Sirtris Pharmaceuticals, Inc. | Methods and related compositions for treating or preventing obesity, insulin resistance disorders, and mitochondrial-associated disorders |
| EP2278999B1 (en) * | 2008-04-21 | 2025-01-29 | Dompé farmaceutici S.p.A. | Auris formulations for treating otic diseases and conditions |
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| ES2785303T3 (es) | 2020-10-06 |
| EP2872128A1 (en) | 2015-05-20 |
| EP2872128B1 (en) | 2020-02-19 |
| EP2872128A4 (en) | 2016-03-30 |
| WO2014014828A1 (en) | 2014-01-23 |
| JP2015524408A (ja) | 2015-08-24 |
| US20150174148A1 (en) | 2015-06-25 |
| US9861651B2 (en) | 2018-01-09 |
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