JP6277125B2 - ホスホリルコリンに対する新規抗体 - Google Patents
ホスホリルコリンに対する新規抗体 Download PDFInfo
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- JP6277125B2 JP6277125B2 JP2014524371A JP2014524371A JP6277125B2 JP 6277125 B2 JP6277125 B2 JP 6277125B2 JP 2014524371 A JP2014524371 A JP 2014524371A JP 2014524371 A JP2014524371 A JP 2014524371A JP 6277125 B2 JP6277125 B2 JP 6277125B2
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201161521593P | 2011-08-09 | 2011-08-09 | |
| US61/521,593 | 2011-08-09 | ||
| PCT/EP2012/065505 WO2013020995A1 (en) | 2011-08-09 | 2012-08-08 | New antibodies against phosphorylcholine |
Publications (3)
| Publication Number | Publication Date |
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| JP2014525233A JP2014525233A (ja) | 2014-09-29 |
| JP2014525233A5 JP2014525233A5 (cg-RX-API-DMAC7.html) | 2015-10-01 |
| JP6277125B2 true JP6277125B2 (ja) | 2018-02-07 |
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| JP2014524371A Expired - Fee Related JP6277125B2 (ja) | 2011-08-09 | 2012-08-08 | ホスホリルコリンに対する新規抗体 |
Country Status (28)
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| MX364425B (es) * | 2011-08-09 | 2019-04-25 | Athera Biotechnologies Ab Star | Nuevos anticuerpos contra fosforilcolina. |
| AU2012294431B2 (en) | 2011-08-09 | 2017-03-30 | Athera Biotechnologies Ab | Antibodies binding to phosphorylcholine (PC) and/or PC conjugates |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| WO2016145128A1 (en) | 2015-03-09 | 2016-09-15 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| WO2017004243A1 (en) | 2015-06-29 | 2017-01-05 | Caris Science, Inc. | Therapeutic oligonucleotides |
| EP3328873B1 (en) | 2015-07-28 | 2025-09-17 | Caris Science, Inc. | Targeted oligonucleotides |
| WO2024194686A2 (en) | 2023-03-17 | 2024-09-26 | Oxitope Pharma B.V. | Anti-phosphocholine antibodies and methods of use thereof |
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| FR2402664A1 (fr) | 1977-09-07 | 1979-04-06 | Agronomique Inst Nat Rech | Produits de couplage phosphorylcholine, composes amines procede d'obtention et applications |
| US5955584A (en) | 1986-03-31 | 1999-09-21 | Charter Ventures | Atherosclerotic plaque specific antigens, antibodies thereto, and uses thereof |
| ES2070820T3 (es) | 1986-08-06 | 1995-06-16 | Scripps Clinic Res | Anticuerpos monoclonales especificos de la apolipoproteina b, producidos por dos nuevos hibridomas. |
| JPH02188532A (ja) | 1989-01-17 | 1990-07-24 | Otsuka Pharmaceut Co Ltd | リポソームワクチン |
| WO1990012632A1 (en) | 1989-04-19 | 1990-11-01 | The United States Of America, Represented By The Secretary, United States Department Of Commerce | Process for removing c-reactive protein and anti-phosphorylcholine antibodies from biological fluids |
| JP3283041B2 (ja) | 1990-07-13 | 2002-05-20 | 学校法人藤田学園 | 人工抗体 |
| WO1992010203A1 (en) | 1990-12-10 | 1992-06-25 | Alving Carl R | A vaccine against cholesterol to prevent hypercholesterolemia and atherosclerosis |
| RU2014609C1 (ru) * | 1991-06-06 | 1994-06-15 | Московский институт тонкой химической технологии им.М.В.Ломоносова | Способ определения белков, специфичных к фосфорилхолину |
| CA2131150A1 (en) | 1992-03-03 | 1993-09-16 | Michel C. Nussenzweig | Receptor complexes with b29 (ig-beta or ig-gamma) and their uses |
| AU5959494A (en) | 1992-12-29 | 1994-07-19 | Entremed, Inc | Vaccines against sterols |
| WO1994018955A1 (en) | 1993-02-22 | 1994-09-01 | Alza Corporation | Compositions for oral delivery of active agents |
| US5455032A (en) | 1993-07-29 | 1995-10-03 | The United States Of America As Represented By The Department Of Health And Human Services | Use of phosphocholine hapten conjugates in vaccines |
| WO1998021581A1 (en) | 1996-11-08 | 1998-05-22 | The Regents Of The University Of California | Methods and reagents for non-invasive imaging of atherosclerotic plaque |
| US6375925B1 (en) | 1996-11-08 | 2002-04-23 | The Regents Of The University Of California | Methods and reagents for non-invasive imaging of atherosclerotic plaque |
| US6225070B1 (en) | 1997-08-07 | 2001-05-01 | The Regents Of The University Of California | Antibodies to oxidation-specific epitopes on lipoprotein and methods for their use in detecting, monitoring and inhibiting the growth of atheroma |
| US20040185039A1 (en) | 2002-08-30 | 2004-09-23 | Heinz Kohler | Therapeutic applications of noncovalent dimerizing antibodies |
| US6300308B1 (en) | 1997-12-31 | 2001-10-09 | Board Of Regents, The University Of Texas System | Methods and compositions for inducing autoimmunity in the treatment of cancers |
| SE9802402D0 (sv) | 1998-07-03 | 1998-07-03 | Karolinska Innovations Ab | Method of diagnosing cardiovascular disease and early atherosclerosis |
| DE69911417T2 (de) | 1998-07-03 | 2004-06-17 | Athera Biotechnologies Ab | Verfahren zur diagnose von gefässerkrankungen und früher atheriosklerose |
| EP1224461B1 (en) | 1999-10-26 | 2011-04-20 | The Regents of The University of California | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease |
| SE0000855D0 (sv) | 2000-03-15 | 2000-03-15 | Karolinska Innovations Ab | Antigenic composition useful as a vaccine against atherosclerosis |
| WO2001088547A2 (en) | 2000-05-12 | 2001-11-22 | The Regents Of The University Of California | Standardized oxidized ldl assay |
| DE10041515A1 (de) | 2000-08-24 | 2002-03-14 | Gerold Schuler | Verfahren zur Herstellung gebrauchsfertiger, Antigen-beladener oder -unbeladener, kryokonservierter reifer dendritischer Zellen |
| US6838452B2 (en) | 2000-11-24 | 2005-01-04 | Vascular Biogenics Ltd. | Methods employing and compositions containing defined oxidized phospholipids for prevention and treatment of atherosclerosis |
| SE0103754L (sv) | 2001-04-05 | 2002-10-06 | Forskarpatent I Syd Ab | Peptider från apolipoprotein B, användning därav immunisering, diagnosmetod eller terapeutisk behandling av ischemiska kardiovaskulära sjukdomar, samt farmaceutisk komposition och vaccin innehållande sådan peptid |
| US20070122419A1 (en) | 2003-04-11 | 2007-05-31 | The Regents Of The University Of California | Methods and compositions for treating atherosclerosis |
| PL1735349T3 (pl) | 2004-04-15 | 2011-03-31 | Athera Biotechnologies Ab | Sposób oceny ryzyka niedokrwiennego schorzenia układu sercowo-naczyniowego za pomocą koniugatów fosforylocholiny |
| JP2008515774A (ja) | 2004-08-03 | 2008-05-15 | ダイアックス コーポレイション | ｈＫ１結合タンパク質 |
| AU2006235507B2 (en) * | 2005-04-12 | 2012-08-30 | Duke University | Method of inducing neutralizing antibodies to human immunodeficiency virus |
| WO2007076200A2 (en) | 2005-11-28 | 2007-07-05 | Medimmune, Inc. | Antagonists of hmgb1 and/or rage and methods of use thereof |
| US20090258005A1 (en) | 2007-05-29 | 2009-10-15 | Trubion Pharmaceuticals Inc. | Therapeutic compositions and methods |
| JP5122908B2 (ja) | 2007-10-17 | 2013-01-16 | 日泉化学株式会社 | 自動車の内装用部材の取り付け構造 |
| WO2010003602A1 (en) | 2008-07-07 | 2010-01-14 | Athera Biotechnologies Ab | New therapeutic and diagnostic methods for alzheimer's disease |
| WO2012010291A1 (en) | 2010-07-21 | 2012-01-26 | Athera Biotechnologies Ab | Diagnostic and therapeutic methods and compositions for metabolic disease |
| JP2014506257A (ja) | 2011-01-06 | 2014-03-13 | ダイアックス コーポレーション | 血漿カリクレイン結合タンパク質 |
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