JP6263200B2 - Two-component fungicidal and bactericidal combination - Google Patents

Description

  The present invention relates to novel active compound combinations, in particular (A) Isotianil (3,4-dichloro-N- (2-cyanophenyl) -5-isothiazole-carboxamide) and (B1) thiazinyl and probenazole At least one further compound (B) selected from the group consisting of members of a group of host defense inducers selected from: and (B2) members of other fungicide groups selected from isopyrazam and propiconazole To fungicidal and / or insecticidal and / or bactericidal compositions.

  The present invention further provides methods for preparing these combinations, compositions comprising these combinations, and organisms, particularly for controlling harmful microorganisms in crop protection and material protection, and for enhancing plant health. Relates to their use as pharmaceutically active combinations. Moreover, the present invention relates to a method for the therapeutic or prophylactic control of phytopathogenic fungi or bacteria of plants or crops, the use of the combination according to the invention for the treatment of seeds, a method of protecting seeds. It is not just about the seeds.

  It is known that isothianyl (compound (A)) is highly suitable for protecting plants against attack by undesirable phytopathogenic fungi and microorganisms, especially bacteria (WO 99/024413, WO 2006/098128, JP 2007-). 84566, WO 96/29871, US-A 5,240,951 and JP-A 06-009313, WO 2010/089055). Isotianil (compound (A)) according to the present invention also mobilizes plant defenses against attack by undesirable phytopathogenic fungi and microorganisms, as well as direct control of phytopathogenic fungi and microorganisms, especially bacteria. Therefore, it is also suitable as a microbicide. In addition, isotianil is also active against pests that damage plants (WO 99/24414). Combinations of isothianyl and selected fungicides are described in WO2005 / 009130 and WO2010 / 069489. The activity of this substance is good; however, at low application rates it is in some cases insufficient.

  In addition, the environmental and economic requirements imposed on modern fungicides and bactericides such as action spectrum, toxicity, selectivity, application rate, residue formation and convenient preparation ability. ) Is constantly increasing and, in addition, new fungicidal and at least some advantages over their known counterparts, for example because there can be resistance problems, and Developing a bactericidal agent is a persistent challenge.

WO99 / 024413 WO2006 / 098128 JP2007-84566 WO96 / 29871 US-A 5,240,951 JP-A06-009313 WO2010 / 089055 WO99 / 24414 WO2005 / 009130 WO2010 / 069489

  The present invention provides, in some embodiments, active compound combinations / compositions that achieve the stated objectives.

  Here, surprisingly, a member of the group of host defense inducers selected from (A) isotianil and (B) (B1) thiazinyl (2.1) and probenazole (2.2) and (B2) isopyrazam A combination comprising at least one further fungicide selected from the group consisting of members of other fungicide groups selected from (2.3) and propiconazole (2.4) from the prior art It has been found that the efficiency is superior to the known combinations.

  The combination according to the invention shows superior efficiency against harmful microorganisms, in particular phytopathogenic fungi and bacteria, compared to compositions known from the prior art.

  In particular, the combinations according to the invention preferably have a synergistic effect in their application as fungicides or fungicides against harmful microorganisms, especially phytopathogenic fungi and bacteria.

  Furthermore, the combination according to the invention has an excellent synergistic effect against harmful microorganisms, in particular phytopathogenic fungi and bacteria, compared to known combinations of the prior art.

  The synergistic effect of the combination and composition according to the invention extends the range of action of component (A) and component (B) in two ways. First, the application rates of component (A) and component (B) are reduced, while the effect remains equally good. Secondly, the combination still achieves a high degree of phytopathogen control even when the two individual compounds are no longer effective at such low application rate ranges. This, on the one hand, substantially broadens the spectrum of phytopathogens that can be controlled, and on the other hand improves safety during use.

  However, in addition to the actual synergistic effect on fungicidal or bactericidal activity, the control combination according to the invention also has the further surprising and advantageous properties that can also be described as broadly synergistic activity. Examples of such advantageous properties that may be mentioned are: broadening the spectrum of fungicidal activity against other phytopathogens, eg resistant strains; reducing active ingredient application rates; even if the individual compounds are not effective at all Sufficient pest control using the composition according to the invention; advantageous behavior during formulation or application, eg during grinding, sieving, emulsifying, dissolving or dispersing; improving storage stability; against light Improved stability; more favorable degradability; improved toxicological or ecotoxicological behavior; improved properties of useful plants including: germination, crop yield, more developed root system, increased tillering, Increased plant height, larger leaf blades, fewer dead rooted leaves, stronger tillers, darker green leaf color, less fertilizer required, fewer seeds required, More productive tillers Early flowering, early grain maturation, less plant planting (overlapping), improved shoot growth, improved plant growth and early germination; or any well known to those skilled in the art Is another advantage.

  The combination according to the invention can also provide an improved osmotic transfer to the active compounds used. Indeed, even though some of the fungicidal compounds used do not have any or sufficient osmotic transfer properties, these compounds can exhibit such properties within the composition according to the invention.

  Similarly, the combination according to the invention can improve the persistence of the fungicidal efficacy of the active compounds used.

  Another advantage of the combination according to the invention is due to the fact that improved therapeutic properties can be achieved.

  Compound (A) Isotianil is a member of a group of host defense inducers selected from (B) (B1) thiazinyl (2.1) and probenazole (2.2) and (B2) isopyrazam (2.3) and pro In combination with at least one compound selected from the group consisting of members of other fungicide groups selected from piconazole (2.4).

(A) Isotianil (chemical name 3,4-dichloro-N- (2-cyanophenyl) -5-isothiazole-carboxamide) and its production method based on commercially available compounds can be found in WO 99/024413 it can.

(2.1) Thiazinyl (Chemical name: N- (3-Chloro-4-methylphenyl) -4-methyl-1,2,3-thiadiazole-5-carboxamide) and production method based on commercially available compounds Can be found in WO96 / 29871 / US6166604.

(2.2) Probenazole (chemical name: 3- (2-propenyloxy) -1,2-benzisothiazole 1,1-dioxide) and its production method based on commercially available compounds are found in US Pat. No. 3,629,428. Can do.

(2.3) Isopyrazam is 3- (difluoromethyl) -1-methyl-N-[(1RS, 4SR, 9RS) -1,2,3,4-tetrahydro-9-isopropyl-1,4-methano. Both syn isomers of naphthalen-5-yl] pyrazole-4-carboxamide and 3- (difluoromethyl) -1-methyl-N-[(1RS, 4SR, 9SR) -1,2,3,4-tetrahydro -9-Isopropyl-1,4-methanonaphthalen-5-yl] pyrazole-4-carboxamide containing both anti isomers. Isopyrazam further comprises isopyrazam (anti-epimer racemate 1RS, 4SR, 9SR), isopyrazam (anti-epimer enantiomer 1R, 4S, 9S), isopyrazam (anti-epimer enantiomer 1S, 4R, 9R), isopyrazam ( synepimeric racemates 1RS, 4SR, 9RS), isopyrazams (syn-epimeric enantiomers 1R, 4S, 9R) and isopyrazams (syn-epimeric enantiomers 1S, 4R, 9S). Isopyrazam and its production process based on commercially available compounds are given in WO 2004/035589.

(2.4) propiconazole (chemical name: 1-[[2- (2,4-dichlorophenyl) -4-propyl-1,3-dioxolan-2-yl] methyl] -1H-1,2,4 -Triazoles) and their production methods based on commercially available compounds can be found in DE-A 2551560.

Compound (A) Isotianil and Compound (B) (2.1, 2.2, 2.3 and 2.4) of the combination or composition according to the invention may be any specific compound between the two essential components. Can be combined in ratio. In the combination or composition according to the invention, compound (A) and compound (B) preferably have a synergistically effective weight ratio of (A) :( B) in the range of 1000: 1 to 1: 1000. Is present in a weight ratio of 500: 1 to 1: 500, most preferably in a weight ratio of 100: 1 to 1: 100. Further ratios of (A) :( B) that can be used according to the invention are in the order of increasing preference: 800: 1 to 1: 800, 700: 1 to 1: 700, 750: 1 to 1: 750, 600: 1 to 1: 600, 400: 1 to 1: 400, 300: 1 to 1: 300, 250: 1 to 1: 250, 200: 1 to 1: 200, 95: 1 to 1:95, 90: 1 to 1:90, 85: 1 to 1:85, 80: 1 to 1:80, 75: 1 to 1:75, 70: 1 to 1:70, 65: 1 to 1:65, 60: 1 1:60, 55: 1 to 1:55, 45: 1 to 1:45, 40: 1 to 1:40, 35: 1 to 1:35, 30: 1 to 1:30, 25: 1 to 1: 25, 20: 1 to 1:20, 15: 1 to 1:15, 10: 1 to 1:10, 5 1 to 1: 5, 4: 1 to 1: 4, 3: 1 to 1: 3, 2: 1 to 1: 2. Preferred ratios are 25: 1 to 1:25, 20: 1 to 1:20, 15: 1 to 1:15, 10: 1 to 1:10, 5: 1 to 1: 5, 4: 1 to 1: 4, 3: 1 to 1: 3, 2: 1 to 1: 2. According to a preferred embodiment of the invention, the combination partner (A) :( B) is present in a weight ratio of 1:25 to 25: 1. More preferred ratios are 10: 1 to 1:10, 5: 1 to 1: 5, 4: 1 to 1: 4, 3: 1 to 1: 3, 2: 1 to 1: 2. The most preferred ratio is 5: 1 to 1: 5, 4: 1 to 1: 4, 3: 1 to 1: 3, 2: 1 to 1: 2.

The following combinations exemplify specific embodiments of the combinations according to the invention:
Isothianyl + thiazinyl; Isothianyl + Probenazole; Isothianyl + Isopyrazam; and Isothianyl + Propiconazole.

The above combinations or compositions may be used alone or in order to broaden the spectrum of action or prevent the development of resistance, other active ingredients such as fungicides, fungicides, acaricides, nematicides, Can be used in combination with herbicides, pesticides, micronutrients and micronutrient-containing compounds, safeners, lipochitooligosaccharide compounds (LCO), soil amendment products or products to reduce plant stress, such as Myconate These are for example:
(The active ingredient identified by its “generic name” herein is known and is described, for example, in Pesticide Manual (“The Pesticide Manual”, 14th Ed., British Crop Protection Council 2006). , Or the Internet (you can find it in http://www.alanwood.net/pesticides as an example).

  Antibiotics such as kasugamycin, streptomycin, oxytetracycline, validamycin, gentamicin, aureofungin, blasticidin-S, cycloheximide, griseofulvin, moloxidine, natamycin, polyoxin, polyoxolim and combinations thereof.

Fungicides:
(1) inhibitors of ergosterol biosynthesis, such as aldimorph, azaconazole, viteltanol, bromconazole, cyproconazole, diclobutrazole, difenoconazole, diniconazole, diniconazole-M, dodemorph, dodemorph acetate, epoxiconazole, Etaconazole, fenarimol, fenbuconazole, fenhexamide, fenpropidin, fenpropimorph, fluquinconazole, flurprimidol, flusilazole, flutriaphor, fluconazole, fluconazole-cis, hexaconazole, imazalyl, imazalyl sulfate, imibenco Nazole, ipconazole, metconazole, microbutanyl, naphthifine, nuarimol, oxpoconazole, paclobutrazol, pe Lazoate, penconazole, piperalin, prochloraz, propiconazole, prothioconazole, piributicalbu, pyrifenox, quinconazole, cimeconazole, spiroxamine, tebuconazole, terbinafine, tetraconazole, triadimephone, triadimenol, tridemorph, triflumizole , Triticonazole, uniconazole, uniconazole-p, biniconazole, voriconazole, 1- (4-chlorophenyl) -2- (1H-1,2,4-triazol-1-yl) cycloheptanol, methyl 1- (2, 2-Dimethyl-2,3-dihydro-1H-inden-1-yl) -1H-imidazole-5-carboxylate, N ′-{5- (difluoromethyl) -2-methyl-4- [3- (trime Tylsilyl) propoxy] phenyl} -N-ethyl-N-methylimidoformamide, N-ethyl-N-methyl-N ′-{2-methyl-5- (trifluoromethyl) -4- [3- (trimethylsilyl) propoxy ] Phenyl} imidoformamide and O- [1- (4-methoxyphenoxy) -3,3-dimethylbutan-2-yl] 1H-imidazole-1-carbothioate.

  (2) Inhibitors of the respiratory chain in complex I or II, such as bixaphene, boscalid, carboxin, diflumetrim, fenflam, fluopyram, flutolanil, floxapyroxad, frametopyl, flumeciclox, racemate of syn-epimer 1RS, 4SR, 9RS and anti-epimer racemate 1RS, 4SR, 9SR mixture), isopyrazam (anti-epimer racemate 1RS, 4SR, 9SR), isopyrazam (anti-epimer enantiomer 1R, 4S, 9S), Isopyrazam (anti-epimer enantiomer 1S, 4R, 9R), isopyrazam (syn epimer racemate 1RS, 4SR, 9RS), isopyrazam (syn-epimer enantiomer 1R, 4S, 9R) , Isopyrazam (syn-epimer enantiomers 1S, 4R, 9S), mepronil, oxycarboxyl, penflufen, penthiopyrad, sedaxane, tifluzamide, 1-methyl-N- [2- (1,1,2,2-tetrafluoroethoxy ) Phenyl] -3- (trifluoromethyl) -1H-pyrazole-4-carboxamide, 3- (difluoromethyl) -1-methyl-N- [2- (1,1,2,2-tetrafluoroethoxy) phenyl ] -1H-pyrazole-4-carboxamide, 3- (difluoromethyl) -N- [4-fluoro-2- (1,1,2,3,3,3-hexafluoropropoxy) phenyl] -1-methyl- 1H-pyrazole-4-carboxamide, N- [1- (2,4-dichlorophenyl) -1-methoxypropane 2-yl] -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide, 5,8-difluoro-N- [2- (2-fluoro-4-{[4- (trifluoromethyl ) Pyridin-2-yl] oxy} phenyl) ethyl] quinazolin-4-amine, N- [9- (dichloromethylene) -1,2,3,4-tetrahydro-1,4-methananaphthalen-5-yl] -3- (Difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide, N-[(1S, 4R) -9- (dichloromethylene) -1,2,3,4-tetrahydro-1,4- Methanonaphthalen-5-yl] -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide and N-[(1R, 4S) -9- (dichloromethylene) -1,2, 3,4-Tetrahydro-1,4-methanonaphthalen-5-yl] -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide.

  (3) Inhibitors of respiratory chain in complex III, such as amethoctrazine, amisulbrom, azoxystrobin, cyazofamid, cumethoxystrobin, cumoxystrobin, dimoxystrobin, enestrobrin, famoxadone, fenamidone, phenoxy Strobin, fluoxastrobin, cresoxime-methyl, metminostrobin, orissastrobin, picoxystrobin, pyraclostrobin, pyramethostrobin, pyroxystrobin, pyribencarb, triclopyricarb, trifloxystrobin, (2E) -2- (2-{[6- (3-chloro-2-methylphenoxy) -5-fluoropyrimidin-4-yl] oxy} phenyl) -2- (methoxyimino) -N-methylethanamide, (2E ) -2- (Metoki Imino) -N-methyl-2- (2-{[({(1E) -1- [3- (trifluoromethyl) phenyl] ethylidene} amino) oxy] methyl} phenyl) ethanamide, (2E) -2- (Methoxyimino) -N-methyl-2- {2-[(E)-({1- [3- (trifluoromethyl) phenyl] ethoxy} imino) methyl] phenyl} ethanamide, (2E) -2- { 2-[({[(1E) -1- (3-{[(E) -1-fluoro-2-phenylethenyl] oxy} phenyl) ethylidene] amino} oxy) methyl] phenyl} -2- (methoxy Imino) -N-methylethanamide, (2E) -2- {2-[({[(2E, 3E) -4- (2,6-dichlorophenyl) but-3-en-2-ylidene] amino} oxy ) Methyl] phenyl} 2- (methoxyimino) -N-methylethanamide, 2-chloro-N- (1,1,3-trimethyl-2,3-dihydro-1H-inden-4-yl) pyridine-3-carboxamide, 5- Methoxy-2-methyl-4- (2-{[({(1E) -1- [3- (trifluoromethyl) phenyl] ethylidene} amino) oxy] methyl} phenyl) -2,4-dihydro-3H- 1,2,4-triazol-3-one, methyl (2E) -2- {2-[({cyclopropyl [(4-methoxyphenyl) imino] methyl} sulfanyl) methyl] phenyl} -3-methoxyprop 2-enoate, N- (3-ethyl-3,5,5-trimethylcyclohexyl) -3- (formylamino) -2-hydroxybenzamide, 2- {2-[(2,5-dimethyl) Phenoxy) methyl] phenyl} -2-methoxy-N-methylacetamide and (2R) -2- {2-[(2,5-dimethylphenoxy) methyl] phenyl} -2-methoxy-N-methylacetamide.

  (4) Mitotic and cell division inhibitors such as benomyl, carbendazim, chlorphenazole, dietofencarb, ethaboxam, fluopicolide, fuberidazole, pencyclon, thiabendazole, thiophanate-methyl, thiophanate, zoxamide, 5-chloro-7- ( 4-Methylpiperidin-1-yl) -6- (2,4,6-trifluorophenyl) [1,2,4] triazolo [1,5-a] pyrimidine and 3-chloro-5- (6-chloro Pyridin-3-yl) -6-methyl-4- (2,4,6-trifluorophenyl) pyridazine.

  (5) Compounds capable of having multi-site action, such as Bordeaux liquid, captahol, captan, chlorothalonil, copper hydroxide, naphthenic acid copper, copper oxide, basic copper chloride, copper sulfate (2+), diclofuranide, dithianon, Dodine, dodin free base, felbum, fluorophorpet, holpet, guazatine, guazatine acetate, iminotadine, iminoctadine albesylate, iminoctazine triacetate, mankappa, mancozeb, manneb, methylam, methylam zinc, oxine-copper, propamidine, propineb Sulfur preparations, including sulfur and calcium polysulfides, thiram, tolylfuranide, dineb and ziram.

  (6) Compounds capable of inducing host defense, such as acibenzoral-S-methyl, isotianil, probenazole and thiazinyl.

  (7) Inhibitors of amino acid and / or protein biosynthesis, such as andprim, blasticidin-S, cyprodinil, kasugamycin, kasugamycin hydrochloride hydrate, mepanipyrim, pyrimethanil and 3- (5-fluoro-3,3,4,4) -Tetramethyl-3,4-dihydroisoquinolin-1-yl) quinoline.

  (8) Inhibitors of ATP production, such as fentin acetate, fentin chloride, fentin hydroxide and silthiophane.

  (9) Inhibitors of cell wall synthesis, such as Bench Avaricarb, Dimethomorph, Flumorph, Iprovaricarb, Mandipropamide, Polyoxin, Polyoxorim, Validamycin A and Varifenalate.

  (10) Inhibitors of lipid and membrane synthesis, such as biphenyl, chloronebu, dichlorane, edifenephos, etridiazole, iodocarb, iprobenphos, isoprothiolane, propamocarb, propamocarb hydrochloride, prothiocarb, pyrazophos, quintozen, technazen and tolcrophos-methyl.

  (11) Inhibitors of melanin biosynthesis, such as carpropamide, diclocimet, phenoxanyl, phthalide, pyroxylone, tricyclazole and 2,2,2-trifluoroethyl {3-methyl-1-[(4-methylbenzoyl) amino] butane- 2-yl} carbamate.

  (12) Inhibitors of nucleic acid synthesis, such as benalaxyl, benalaxyl-M (kiralaxyl), bupirimate, cloziracone, dimethylirimol, ethylimol, furalaxyl, himexazole, metalaxyl, metalaxyl-M (mephenoxam), ofulase, oxadixyl and oxophosphoric acid.

  (13) Signal transduction inhibitors such as clozolinate, fenpicuronyl, fludioxonil, iprodione, procymidone, quinoxyphene and vinclozoline.

  (14) Compounds that can act as uncouplers, such as binapacryl, dinocup, ferrimzone, fluazinam and meptyldinocup.

  (15) Further compounds such as benazole, betoxazine, capsimycin, carvone, quinomethionate, pliophenone (clazaphenone), kufuraneb, cyflufenamide, simoxanyl, cyprosulfamide, dazomet, debacarb, dichlorophene, dichromedene, difenzocote, Zoquat methyl sulfate, diphenylamine, ecomate, fenpyrazamine, flumethoverl, fluoroimide, fursulfamide, fluthianyl, fosetyl-aluminum, fosetyl-calcium, fosetyl-sodium, hexachlorobenzene, ilumamycin, metasulfocarb, methylisothiocyanate, metolaphenone , Mildiomycin, Natamycin, Ni Dimethyldithiocarbamate, nitrotal-isopropyl, octylinone, oxamocarb, oxyfenthine, pentachlorophenol and salts, phenothrin, phosphorous acid and its salts, propamocarb-fosetylate, propanocin-sodium, proquinazide, pyrimorph, (2E) -3- (4-tert-butylphenyl) -3- (2-chloropyridin-4-yl) -1- (morpholin-4-yl) prop-2-en-1-one, (2Z) -3 -(4-tert-butylphenyl) -3- (2-chloropyridin-4-yl) -1- (morpholin-4-yl) prop-2-en-1-one, pyrrolnitrin, tebufloquine, teclophthalam , Torniphanide, triazoxide, trichlamide, the Rilamide, (3S, 6S, 7R, 8R) -8-benzyl-3-[({3-[(isobutyryloxy) methoxy] -4-methoxypyridin-2-yl} carbonyl) amino] -6-methyl -4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate, 1- (4- {4-[(5R) -5- (2,6-difluorophenyl) -4,5 -Dihydro-1,2-oxazol-3-yl] -1,3-thiazol-2-yl} piperidin-1-yl) -2- [5-methyl-3- (trifluoromethyl) -1H-pyrazole- 1-yl] ethanone, 1- (4- {4-[(5S) -5- (2,6-difluorophenyl) -4,5-dihydro-1,2-oxazol-3-yl] -1,3 -Thiazol-2-yl} piperidin-1-yl) 2- [5-Methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl] ethanone, 1- (4- {4- [5- (2,6-difluorophenyl) -4,5-dihydro -1,2-oxazol-3-yl] -1,3-thiazol-2-yl} piperidin-1-yl) -2- [5-methyl-3- (trifluoromethyl) -1H-pyrazol-1- Yl] ethanone, 1- (4-methoxyphenoxy) -3,3-dimethylbutan-2-yl 1H-imidazole-1-carboxylate, 2,3,5,6-tetrachloro-4- (methylsulfonyl) pyridine 2,3-dibutyl-6-chlorothieno [2,3-d] pyrimidin-4 (3H) -one, 2- [5-methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl]- 1- (4- { -[(5R) -5-phenyl-4,5-dihydro-1,2-oxazol-3-yl] -1,3-thiazol-2-yl} piperidin-1-yl) ethanone, 2- [5- Methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl] -1- (4- {4-[(5S) -5-phenyl-4,5-dihydro-1,2-oxazole-3- Yl] -1,3-thiazol-2-yl} piperidin-1-yl) ethanone, 2- [5-methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl] -1- {4- [4- (5-Phenyl-4,5-dihydro-1,2-oxazol-3-yl) -1,3-thiazol-2-yl] piperidin-1-yl} ethanone, 2-butoxy-6-iodo -3-propyl-4H-chromen-4-one, 2 Chloro-5- [2-chloro-1- (2,6-difluoro-4-methoxyphenyl) -4-methyl-1H-imidazol-5-yl] pyridine, 2-phenylphenol and salts, 3- (4 4,5-trifluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl) quinoline, 3,4,5-trichloropyridine-2,6-dicarbonitrile, 3- [5- (4 -Chlorophenyl) -2,3-dimethyl-1,2-oxazolidine-3-yl] pyridine, 3-chloro-5- (4-chlorophenyl) -4- (2,6-difluorophenyl) -6-methylpyridazine, 4- (4-chlorophenyl) -5- (2,6-difluorophenyl) -3,6-dimethylpyridazine, 5-amino-1,3,4-thiadiazole-2-thiol, 5-chloro Rho-N′-phenyl-N ′-(prop-2-yn-1-yl) thiophene-2-sulfonohydrazide, 5-fluoro-2-[(4-fluorobenzyl) oxy] pyrimidin-4-amine, 5-fluoro-2-[(4-methylbenzyl) oxy] pyrimidin-4-amine, 5-methyl-6-octyl [1,2,4] triazolo [1,5-a] pyrimidin-7-amine, ethyl (2Z) -3-amino-2-cyano-3-phenylprop-2-enoate, N ′-(4-{[3- (4-chlorobenzyl) -1,2,4-thiadiazol-5-yl] Oxy} -2,5-dimethylphenyl) -N-ethyl-N-methylimidoformamide, N- (4-chlorobenzyl) -3- [3-methoxy-4- (prop-2-yn-1-yloxy) Phenyl] Panamide, N-[(4-chlorophenyl) (cyano) methyl] -3- [3-methoxy-4- (prop-2-yn-1-yloxy) phenyl] propanamide, N-[(5-bromo-3 -Chloropyridin-2-yl) methyl] -2,4-dichloropyridine-3-carboxamide, N- [1- (5-bromo-3-chloropyridin-2-yl) ethyl] -2,4-dichloropyridine -3-carboxamide, N- [1- (5-bromo-3-chloropyridin-2-yl) ethyl] -2-fluoro-4-iodopyridine-3-carboxamide, N-{(E)-[(cyclo Propylmethoxy) imino] [6- (difluoromethoxy) -2,3-difluorophenyl] methyl} -2-phenylacetamide, N-{(Z)-[(cyclopropylmethoxy Imino] [6- (difluoromethoxy) -2,3-difluorophenyl] methyl} -2-phenylacetamide, N ′-{4-[(3-tert-butyl-4-cyano-1,2-thiazole-5 -Yl) oxy] -2-chloro-5-methylphenyl} -N-ethyl-N-methylimidoformamide, N-methyl-2- (1-{[5-methyl-3- (trifluoromethyl) -1H -Pyrazol-1-yl] acetyl} piperidin-4-yl) -N- (1,2,3,4-tetrahydronaphthalen-1-yl) -1,3-thiazol-4-carboxamide, N-methyl-2 -(1-{[5-Methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl] acetyl} piperidin-4-yl) -N-[(1R) -1,2,3,4- Tetrahydro Naphthalen-1-yl] -1,3-thiazole-4-carboxamide, N-methyl-2- (1-{[5-methyl-3- (trifluoromethyl) -1H-pyrazol-1-yl] acetyl} Piperidin-4-yl) -N-[(1S) -1,2,3,4-tetrahydronaphthalen-1-yl] -1,3-thiazole-4-carboxamide, pentyl {6-[({[(1 -Methyl-1H-tetrazol-5-yl) (phenyl) methylidene] amino} oxy) methyl] pyridin-2-yl} carbamate, phenazine-1-carboxylic acid, quinolin-8-ol, quinolin-8-ol sulfate (2: 1) and tert-butyl {6-[({[(1-methyl-1H-tetrazol-5-yl) (phenyl) methylene] amino} oxy) methyl] Lysine-2-yl} carbamate.

  (16) Further compounds such as 1-methyl-3- (trifluoromethyl) -N- [2 ′-(trifluoromethyl) biphenyl-2-yl] -1H-pyrazole-4-carboxamide, N- (4 ′ -Chlorobiphenyl-2-yl) -3- (difluoromethyl) -1-methyl-1H-pyrazole-4-carboxamide, N- (2 ', 4'-dichlorobiphenyl-2-yl) -3- (difluoromethyl ) -1-Methyl-1H-pyrazole-4-carboxamide, 3- (Difluoromethyl) -1-methyl-N- [4 ′-(trifluoromethyl) biphenyl-2-yl] -1H-pyrazole-4-carboxamide N- (2 ′, 5′-difluorobiphenyl-2-yl) -1-methyl-3- (trifluoromethyl) -1H-pyrazole-4-carboxyl 3- (difluoromethyl) -1-methyl-N- [4 ′-(prop-1-in-1-yl) biphenyl-2-yl] -1H-pyrazole-4-carboxamide, 5-fluoro-1 , 3-Dimethyl-N- [4 ′-(prop-1-in-1-yl) biphenyl-2-yl] -1H-pyrazole-4-carboxamide, 2-chloro-N- [4 ′-(propa- 1-in-1-yl) biphenyl-2-yl] pyridine-3-carboxamide, 3- (difluoromethyl) -N- [4 ′-(3,3-dimethylbut-1-in-1-yl) biphenyl -2-yl] -1-methyl-1H-pyrazole-4-carboxamide, N- [4 ′-(3,3-dimethylbut-1-in-1-yl) biphenyl-2-yl] -5-fluoro -1,3-dimethyl-1H- Razole-4-carboxamide, 3- (difluoromethyl) -N- (4'-ethynylbiphenyl-2-yl) -1-methyl-1H-pyrazole-4-carboxamide, N- (4'-ethynylbiphenyl-2- Yl) -5-fluoro-1,3-dimethyl-1H-pyrazole-4-carboxamide, 2-chloro-N- (4′-ethynylbiphenyl-2-yl) pyridine-3-carboxamide, 2-chloro-N— [4 ′-(3,3-Dimethylbut-1-in-1-yl) biphenyl-2-yl] pyridine-3-carboxamide, 4- (difluoromethyl) -2-methyl-N- [4 ′-( Trifluoromethyl) biphenyl-2-yl] -1,3-thiazole-5-carboxamide, 5-fluoro-N- [4 ′-(3-hydroxy-3-methylbuta-1) -In-1-yl) biphenyl-2-yl] -1,3-dimethyl-1H-pyrazole-4-carboxamide, 2-chloro-N- [4 '-(3-hydroxy-3-methylbut-1-yne) -1-yl) biphenyl-2-yl] pyridine-3-carboxamide, 3- (difluoromethyl) -N- [4 ′-(3-methoxy-3-methylbut-1-in-1-yl) biphenyl-2 -Yl] -1-methyl-1H-pyrazole-4-carboxamide, 5-fluoro-N- [4 '-(3-methoxy-3-methylbut-1-in-1-yl) biphenyl-2-yl]- 1,3-dimethyl-1H-pyrazole-4-carboxamide, 2-chloro-N- [4 ′-(3-methoxy-3-methylbut-1-in-1-yl) biphenyl-2-yl] pyridine-3 -Cal Xamide, (5-bromo-2-methoxy-4-methylpyridin-3-yl) (2,3,4-trimethoxy-6-methylphenyl) methanone, N- [2- (4-{[3- (4 -Chlorophenyl) prop-2-yn-1-yl] oxy} -3-methoxyphenyl) ethyl] -N2- (methylsulfonyl) valinamide, 4-oxo-4-[(2-phenylethyl) amino] butanoic acid and But-3-yn-1-yl {6-[({[(Z)-(1-methyl-1H-tetrazol-5-yl) (phenyl) methylene] amino} oxy) methyl] pyridin-2-yl} Carbamates, and combinations thereof.

Insecticides, acaricides and nematicides:
Acetylcholinesterase (AChE) inhibitors, such as carbamates, such as alaniccarb, aldicarb, bendiocarb, benfuracarb, butoxycarboxym, butoxycarboxym, carbaryl, carbofuran, carbosulfan, etiophencarb, fenobucarb, formethanate, furthiocarb, isoprocarb, methiocarb, mesomil , Metorcarb, oxamyl, pyrimicarb, propoxyl, thiodicarb, thiophanox, triazamate, trimetacarb, XMC and xylylcarb; or organophosphates such as acephate, azamethiphos, azinephos-ethyl, azinephos-methyl, kazusafos, chloroethoxyphos, chlor Fenbinphos, Chlormefos, Chlorpyrifos, Chlorpi Phos-methyl, coumaphos, cyanophos, demeton-S-methyl, diazinon, dichlorvos / DDVP, dicrotophos, dimethoate, dimethylvinphos, disulfotone, EPN, ethion, etoprophos, famfur, phenamiphos, fenitrothion, fenthion, phosthiazeto, heptenophos, imitationaphos Isofenphos, isopropyl O- (methoxyaminothio-phosphoryl) salicylate, isoxathion, malathion, mecarbam, methamidophos, methidathion, mevinphos, monocrotophos, nared, ometoate, oxydemeton-methyl, parathion, parathion-methyl, phentoate, folate, hosalon, phosmet Phosphamidon, phoxime, pyrimiphos-methyl, propenofos, propeta Phosphite, prothiofos, pyraclofos, pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos, thiometon, triazophos, trichlorfon (Triclorfon) and vamidothion.

  GABAergic chloride channel antagonists such as cyclodiene organochlorines such as chlordane and endosulfan; or phenylpyrazole (fiprol) such as ethiprole and fipronil.

  Sodium channel modulators / voltage-dependent sodium channel blockers, such as pyrethroids, such as acrinathrin, alletrin, d-cis-trans alletrin, d-trans alletrin, bifenthrin, bioalletrin, bioarethrin S-cyclopentenyl isomers, violesmethrin, cycloprotorin , Cyfluthrin, beta-cyfluthrin, cyhalothrin, lambda-cyhalothrin, gamma-cyhalothrin, cypermethrin, alpha-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, ciphenothrin [(1R) -trans isomerism Body], deltamethrin, empentrin [(EZ)-(1R) isomer), esfenvalerate, etofenprox, fenpropa Phosphorus, fenvalerate, flucitrinate, flumethrinate, tau-fulvalinate, halfenprox, imiprotrine, cadetrin, permethrin, phenothrin [(1R) -trans isomer), praretrin, pyrethrin (insecticidal chrysanthemum), resmethrin, silafluophene, tefluthrin, Tetramethrin, tetramethrin [(1R) isomer)], tralomethrin and transfluthrin; or DDT; or methoxychlor.

  Nicotinic acetylcholine receptor (nAChR) agonists such as neonicotinoids such as acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid and thiamethoxam; or nicotine.

  Nicotinic acetylcholine receptor (nAChR) allosteric activators such as spinosyns such as spinetoram and spinosad.

  Chloride channel activators such as avermectin / milbemycin, eg abamectin, emamectin benzoate, lepimectin and milbemectin.

  Juvenile hormone mimics, such as juvenile hormone analogs such as hydroprene, quinoprene and methoprene; or phenoxycarb; or pyriproxyfen.

  Various non-specific (multi-site) inhibitors such as alkyl halides, such as methyl bromide and other alkyl halides; or chloropicrin; or sulfuryl fluoride; or borax; or tartar.

  Selective symbiotic feeding inhibitors such as pymetrozine; or flonicamid.

  Tick growth inhibitors, such as clofentezin, hexothiazox and difluvidazine; or etoxazole.

  Microbial disruptors of insect intestinal membranes, such as Bacillus thuringiensis subspecies isspecificus, Bacillus sphaericus subspecies, and -Thuringiensis subspecies Kurstaki (Bacillus thuringiensis subspecies kurstaki), Bacillus thuringiensis subspecies tenebrionis and BT crop protein: C y1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34 / 35Ab1.

  Inhibitors of mitochondrial ATP synthase, such as diafenthiuron; or organotin acaricides, such as azocyclotin, cyhexatin and phenbutatin oxide; or propargite; or tetradiphone.

  Uncouplers of oxidative phosphorylation via proton gradient decay, such as chlorfenapyr, DNOC and sulfuramide.

  Nicotinic acetylcholine receptor (nAChR) channel blockers such as bensultap, cartap hydrochloride, thiocyclam and thiosultap-sodium.

  Inhibitors of chitin biosynthesis, type 0, such as bistrifluron, chlorfluazuron, diflubenzuron, fullcycloxuron, flufenoxuron, hexaflumuron, lufenuron, novallon, nobiflumuron, teflubenzuron and triflumuuron.

  Inhibitors of chitin biosynthesis, type 1, such as buprofezin.

  Molting disruptors such as cyromazine.

  Ecdysone receptor agonists such as chromafenozide, halofenozide, methoxyphenozide and tebufenozide.

  Octopamine receptor agonists such as Amitraz.

  Mitochondrial complex III electron transport inhibitors such as hydramethylnon; or acequinosyl; or fluacrylpyrim.

  Mitochondrial complex I electron transport inhibitors, such as METI acaricides, such as phenazaquin, fenpyroximate, pyrimidifen, pyridaben, tebufenpyrad and tolfenpyrad; or rotenone (Derris).

  Voltage-gated sodium channel blockers, such as indoxacarb; or metaflumizone.

  Inhibitors of acetyl CoA carboxylase, such as derivatives of tetronic and tetramic acids, such as spirodiclofen, spiromesifen and spirotetramat.

  Mitochondrial complex IV electron transport inhibitors, such as phosphines, such as aluminum phosphide, calcium phosphide, phosphine and zinc phosphide; or cyanide.

  Mitochondrial complex II electron transport inhibitors, such as sienopyrafen.

  Ryanodine receptor modulators such as diamides, such as chlorantraniliprole and fulvendiamide.

Additional active ingredients with unknown or unknown mode of action, such as amidoflumet, azadirachtin, bencrothiaz, benzoximate, biphenazate, bromopropyrate, quinomethionate, cryolite, cyantraniliprole (siadipyl), cyflumethofene, dicohol, difluvidazine, fluenesulfone , Flufenerim, flufiprole, fluopyram, fufenozide, imidaclotides, iprodione, pyridalyl, pyrifluquinazone and iodomethane; and products based on Bacillus films (I-1582, BioNeem, Votivo) or the following known compounds 1: 3-bromo-N- {2-bromo-4-chloro-6-[(1-cyclopropylethyl) ca Rubamoyl] phenyl} -1- (3-chloropyridin-2-yl) -1H-pyrazole-5-carboxamide (known from WO 2005/077934), 4-{[(6-bromopyridin-3-yl) methyl] ( 2-fluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/115644), 4-{[(6-fluoropyridin-3-yl) methyl] (2,2-difluoroethyl) amino} furan -2 (5H) -one (known from WO 2007/115644), 4-{[(2-chloro-1,3-thiazol-5-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) -One (known from WO 2007/115644), 4-{[(6-chloropyridin-3-yl) methyl] (2-fluoroethyl) amino} fura -2 (5H) -one (known from WO 2007/115644), 4-{[(6-chloropyridin-3-yl) methyl] (2,2-difluoroethyl) amino} furan-2 (5H) -one ( WO 2007/115644), 4-{[(6-Chloro-5-fluoropyridin-3-yl) methyl] (methyl) amino} furan-2 (5H) -one (known from WO 2007/115643), 4- {[(5,6-dichloropyridin-3-yl) methyl] (2-fluoroethyl) amino} furan-2 (5H) -one (known from WO 2007/115646), 4-{[(6-chloro-5 -Fluoropyridin-3-yl) methyl] (cyclopropyl) amino} furan-2 (5H) -one (known from WO 2007/115643), 4-{[(6- Olopyridin-3-yl) methyl] (cyclopropyl) amino} furan-2 (5H) -one (known from EP-A-0539588), 4-{[(6-chloropyridin-3-yl) methyl] (methyl ) Amino} furan-2 (5H) -one (known from EP-A-0539588), {[1- (6-chloropyridin-3-yl) ethyl] (methyl) oxide-λ4-sulfanilidene} cyanamide (WO2007 / 149134) and its diastereomers {[(1R) -1- (6-chloropyridin-3-yl) ethyl] (methyl) oxide-λ4-sulfanilidene} cyanamide (A) and {[(1S) -1- (6-chloropyridin-3-yl) ethyl] (methyl) oxide-λ4-sulfanilidene} cyanamide (B) Known from WO 2007/149134) as well as sulfoxafurol (also known from WO 2007/149134) as well as its diastereomers, the group of diastereomers A [(R) -methyl (oxide) {(1R) -1 -[6- (trifluoromethyl) pyridin-3-yl] ethyl} -λ4-sulfanylidene] cyanamide (A1) and [(S) -methyl (oxide) {(1S) -1- [6- (trifluoromethyl ) Pyridin-3-yl] ethyl} -λ4-sulfanylidene] cyanamide (A2) (also known from WO2010 / 074747, WO2010 / 074751), referred to as the group of diastereomers B [(R) -methyl (oxide) {( 1S) -1- [6- (trifluoromethyl) pyridin-3-yl] ethyl } -Λ4-sulfanylidene] cyanamide (B1) and [(S) -methyl (oxide) {(1R) -1- [6- (trifluoromethyl) pyridin-3-yl] ethyl} -λ4-sulfanylidene] cyanamide ( B2) (also known from WO2010 / 074747, WO2010 / 074751), and 11- (4-chloro-2,6-dimethylphenyl) -12-hydroxy-1,4-dioxa-9-azadispiro [4.2.4. .2] Tetradeca-11-en-10-one (known from WO 2006/089633), 3- (4′-fluoro-2,4-dimethylbiphenyl-3-yl) -4-hydroxy-8-oxa-1- Azaspiro [4.5] dec-3-en-2-one (known from WO 2008/067911), 1- {2-fluoro-4 Methyl-5-[(2,2,2-trifluoroethyl) sulfinyl] phenyl} -3- (trifluoromethyl) -1H-1,2,4-triazol-5-amine (known from WO 2006/043635), [(3S, 4aR, 12R, 12aS, 12bS) -3-[(cyclopropylcarbonyl) oxy] -6,12-dihydroxy-4,12b-dimethyl-11-oxo-9- (pyridin-3-yl)- 1,3,4,4a, 5,6,6a, 12,12a, 12b-decahydro-2H, 11H-benzo [f] pyrano [4,3-b] chromen-4-yl] methyl cyclopropanecarboxylate ( WO2008 / 066153), 2-cyano-3- (difluoromethoxy) -N, N-dimethylbenzenesulfonamide (WO2006) 056433), 2-cyano-3- (difluoromethoxy) -N-methylbenzenesulfonamide (known from WO2006 / 100288), 2-cyano-3- (difluoromethoxy) -N-ethylbenzenesulfonamide (WO2005 / 035486). Known), 4- (difluoromethoxy) -N-ethyl-N-methyl-1,2-benzothiazol-3-amine 1,1-dioxide (known from WO 2007/057407), N- [1- (2, 3-dimethylphenyl) -2- (3,5-dimethylphenyl) ethyl] -4,5-dihydro-1,3-thiazol-2-amine (known from WO 2008/104503), {1 ′-[(2E) -3- (4-Chlorophenyl) prop-2-en-1-yl] -5-fluorospiro [India -3,4'-piperidin] -1 (2H) -yl} (2-chloropyridin-4-yl) methanone (known from WO2003 / 106457), 3- (2,5-dimethylphenyl) -4-hydroxy -8-methoxy-1,8-diazaspiro [4.5] dec-3-en-2-one (known from WO 2009/049851), 3- (2,5-dimethylphenyl) -8-methoxy-2-oxo -1,8-diazaspiro [4.5] dec-3-en-4-yl ethyl carbonate (known from WO 2009/049851), 4- (but-2-yn-1-yloxy) -6- (3,5 -Dimethylpiperidin-1-yl) -5-fluoropyrimidine (known from WO 2004/099160), (2,2,3,3,4,4,5,5-octafluoropentyl) (3 , 3,3-trifluoropropyl) malononitrile (known from WO 2005/063094), (2,2,3,3,4,4,5,5-octafluoropentyl) (3,3,4,4,4- Pentafluorobutyl) malononitrile (known from WO 2005/063094), 8- [2- (cyclopropylmethoxy) -4- (trifluoromethyl) phenoxy] -3- [6- (trifluoromethyl) pyridazin-3-yl] -3-Azabicyclo [3.2.1] octane (known from WO 2007/040280), 2-ethyl-7-methoxy-3-methyl-6-[(2,2,3,3-tetrafluoro-2,3 -Dihydro-1,4-benzodioxin-6-yl) oxy] quinolin-4-yl methyl carbonate (known from JP 2008/110953) ), 2-ethyl-7-methoxy-3-methyl-6-[(2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodioxin-6-yl) oxy] quinoline- 4-yl acetate (known from JP2008 / 110953), PF1364 (CAS-Reg. No. 1204776-60-2) (known from JP 2010/018586), 5- [5- (3,5-dichlorophenyl) -5- (trifluoromethyl) -4,5-dihydro-1,2-oxazol-3-yl ] -2- (1H-1,2,4-triazol-1-yl) benzonitrile (known from WO 2007/07459), 5- [5- (2-chloropyridin-4-yl) -5- (trifluoro Methyl) -4,5-dihydro-1,2-oxazol-3-yl] -2- (1H-1,2,4-triazol-1-yl) benzonitrile (known from WO 2007/07459), 4- [ 5- (3,5-dichlorophenyl) -5- (trifluoromethyl) -4,5-dihydro-1,2-oxazol-3-yl] -2-methyl-N- {2-oxo-2 [(2,2,2-trifluoroethyl) amino] ethyl} benzamide (known from WO 2005/085216), 4-{[(6-chloropyridin-3-yl) methyl] (cyclopropyl) amino} -1, 3-Oxazol-2 (5H) -one, 4-{[(6-chloropyridin-3-yl) methyl] (2,2-difluoroethyl) amino} -1,3-oxazol-2 (5H) -one 4-{[(6-chloropyridin-3-yl) methyl] (ethyl) amino} -1,3-oxazol-2 (5H) -one, 4-{[(6-chloropyridin-3-yl) Methyl] (methyl) amino} -1,3-oxazol-2 (5H) -one (all known from WO2010 / 005692), NNI-0711 (known from WO2002096882), 1-a Tyl-N- [4- (1,1,1,3,3,3-hexafluoro-2-methoxypropan-2-yl) -3-isobutylphenyl] -N-isobutyryl-3,5-dimethyl-1H -Pyrazole-4-carboxamide (known from WO2002099682), methyl 2- [2-({[3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazol-5-yl] carbonyl} amino) -5-chloro-3-methylbenzoyl] -2-methylhydrazinecarboxylate (known from WO 2005/085216), methyl 2- [2-({[3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazol-5-yl] carbonyl} amino) -5-cyano-3-methylbenzoyl] -2-ethylhydrazinecarboxylate (WO2) 05/085216), methyl 2- [2-({[3-bromo-1- (3-chloropyridin-2-yl) -1H-pyrazol-5-yl] carbonyl} amino) -5-cyano- 3-methylbenzoyl] -2-methylhydrazinecarboxylate (known from WO 2005/085216), methyl 2- [3,5-dibromo-2-({[3-bromo-1- (3-chloropyridin-2-yl] ) -1H-pyrazol-5-yl] carbonyl} amino) benzoyl] -1,2-diethylhydrazinecarboxylate (known from WO 2005/085216), methyl 2- [3,5-dibromo-2-({[3- Bromo-1- (3-chloropyridin-2-yl) -1H-pyrazol-5-yl] carbonyl} amino) benzoyl] -2-ethyl Razine carboxylate (known from WO 2005/085216), (5RS, 7RS; 5RS, 7SR) -1- (6-chloro-3-pyridylmethyl) -1,2,3,5,6,7-hexahydro-7- Methyl-8-nitro-5-propoxyimidazo [1,2-a] pyridine (known from WO 2007/101369), 2- {6- [2- (5-fluoropyridin-3-yl) -1,3-thiazole -5-yl] pyridin-2-yl} pyrimidine (known from WO 2010/006713), 2- {6- [2- (pyridin-3-yl) -1,3-thiazol-5-yl] pyridin-2- Yl} pyrimidine (known from WO 2010/006713), 1- (3-chloropyridin-2-yl) -N- [4-cyano-2
-Methyl-6- (methylcarbamoyl) phenyl] -3-{[5- (trifluoromethyl) -1H-tetrazol-1-yl] methyl} -1H-pyrazole-5-carboxamide (known from WO 2010/066952), 1- (3-Chloropyridin-2-yl) -N- [4-cyano-2-methyl-6- (methylcarbamoyl) phenyl] -3-{[5- (trifluoromethyl) -2H-tetrazole-2 -Yl] methyl} -1H-pyrazole-5-carboxamide (known from WO2010 / 066952), N- [2- (tert-butylcarbamoyl) -4-cyano-6-methylphenyl] -1- (3-chloropyridine -2-yl) -3-{[5- (trifluoromethyl) -1H-tetrazol-1-yl] methyl} -1H-pyrazole 5-carboxamide (known from WO 2010/066952), N- [2- (tert-butylcarbamoyl) -4-cyano-6-methylphenyl] -1- (3-chloropyridin-2-yl) -3-{[ 5- (Trifluoromethyl) -2H-tetrazol-2-yl] methyl} -1H-pyrazole-5-carboxamide (known from WO 2010/066952) and (1E) -N-[(6-chloropyridin-3-yl ) Methyl] -N′-cyano-N- (2,2-difluoroethyl) ethanimidoamide (known from WO 2008/009360).

Micronutrients and micronutrient-containing compounds:
In the context of the present invention, the micronutrient and the micronutrient-containing compound are a group consisting of at least one metal ion selected from the group consisting of zinc, manganese, molybdenum, iron and copper or an active ingredient containing micronutrient boron. Relates to a compound selected from More preferably, these micronutrients and micronutrient-containing compounds also contain the zinc-containing compounds propineb, polyoxin Z (zinc salt), dineb, dilam, zinc thiodazole, zinc naphthenate and mancozeb (which also contains manganese) ), Manneb, methylam and mankappa of manganese-containing compounds (which also contain copper), Felbum of iron-containing compounds, Bordeaux liquid of copper (Cu) and copper-containing compounds, Burgundy liquid, Cheshunt liquid mixture), basic copper chloride, copper sulfate, basic copper sulfate (eg tribasic copper sulfate), copper oxide, copper octoate, copper hydroxide, oxine-copper, copper ammonium acetate, copper naphthenate, chelation Copper (for example amino acid key Mankappa, acipetacs-copper, copper acetate, basic copper carbonate, copper oleate, copper silicate, copper zinc chromate, kufuranebu, cuprobam, saisentong and thiodiazole- Selected from the group consisting of copper, and combinations thereof.

  The combination according to the invention can be the composition itself, but the final composition used is usually compound (A), (B1) a member of the group of host defense inducers selected from thiazinyl and probenazole and (B2 ) By mixing with at least one compound (B) selected from the group consisting of members of other fungicide groups selected from isopyrazam and propiconazole, and by mixing with an inert carrier, and if necessary , Surfactants and / or other auxiliary agents for the formulation, such as bulking agents, etc., and combinations of oil formulations, emulsions, flowable formulations, wettable powders, granular wettable powders, powders, granules etc. It is prepared by formulating into Formulations used alone or by adding another inert component can be used as a pesticide.

  According to a preferred embodiment of the present invention, a composition is prepared comprising mixing a synergistically effective combination according to the present invention with a bulking agent, a surfactant or a combination thereof.

  Certain additional components of this final composition will be described later.

  “Composition” is a member of a group of compounds (A) and (B1) a host defense inducer selected from thiazinyl and probenazole and (B2) a member of another fungicide group selected from isopyrazam and propiconazole It can be prepared by formulating at least one compound (B) selected from the group consisting of as described above, and then making the formulation or dilutions thereof.

  For clarity, the combinations are compounds (A) and (B1) members of the group of host defense inducers selected from thiazinyl and probenazole, and (B2) other fungicides selected from isopyrazam and propiconazole. While means a physical combination with at least one compound (B) selected from the group consisting of members of the group, the composition comprises said combination with further additives such as surfactants, solvents, carriers, It means a combination of pigments, antifoaming agents, thickeners, extenders and the like suitable for agricultural applications.

  Accordingly, the present invention also relates to a composition comprising an effective but non-phytotoxic amount of a combination of the present invention for controlling harmful microorganisms, particularly harmful fungi and bacteria. These are preferably fungicidal compositions comprising agriculturally suitable auxiliaries, solvents, carriers, surfactants or extenders.

  In the context of the present invention, “control of harmful microorganisms” means a reduction of infection by harmful microorganisms compared to untreated plants, measured as fungicidal efficacy, preferably not treated 25-100% reduction compared to plants (100%), more preferably 40-100% reduction compared to untreated plants (100%); even more preferably infection by harmful microorganisms Is completely suppressed (70 to 100%). Control may be therapeutic, ie for the treatment of already infected plants, or protective, ie for the protection of plants that are not yet infected.

  An “effective but non-phytotoxic amount” is sufficient to satisfactorily control a fungal disease of a plant or to completely eradicate a fungal disease, while at the same time causing some significant phytotoxic symptoms. It means no amount of the composition of the present invention. In general, this application rate can vary within a relatively wide range. It depends on several factors, for example the fungus to be controlled, the plant, the climatic conditions and the components of the composition of the invention.

  The present invention also relates to a method for controlling phytopathogenic microorganisms, including fungi and bacteria, which comprises contacting said microorganisms or their habitat with the above composition.

  The present invention further relates to a method for treating seed, comprising contacting said seed with said composition. According to one preferred embodiment of the invention, the seed is treated with component (A) at the same time as it is treated with component (s) (B). According to another preferred embodiment of the invention, the seed is treated with component (A) at a different time than it is treated with component (s) (B).

  Finally, the present invention also relates to seed treated with the composition described above.

Formulations Suitable organic solvents include all polar and nonpolar organic solvents commonly used for formulation purposes. Preferably, the solvent is a ketone, such as methyl-isobutyl-ketone and cyclohexanone, an amide, such as dimethylformamide and an alkanecarboxylic acid amide, such as N, N-dimethyldecanamide and N, N-dimethyloctaneamide, and Cyclic solvents such as N-methyl-pyrrolidone, N-octyl-pyrrolidone, N-dodecyl-pyrrolidone, N-octyl-caprolactam, N-dodecyl-caprolactam and butyrolactone, as well as strongly polar solvents such as dimethyl sulfoxide, and aromatics Group hydrocarbons such as xylol, Solvesso ™, mineral oils such as white spirit, petroleum, alkylbenzene and spindle oils, and esters such as propylene group Recall-monomethyl ether acetate, adipic acid dibutyl ester, acetic acid hexyl ester, acetic acid heptyl ester, citric acid tri-n-butyl ester and phthalic acid di-n-butyl ester, and also alcohol, eg benzyl alcohol and 1 -Selected from methoxy-2-propanol.

  According to the invention, the carrier is a natural or synthetic, organic or inorganic substance with which the active ingredients are mixed or combined for better applicability, in particular for application to plants or plant parts or seeds. . The carrier may be solid or liquid and is generally inert and should be suitable for use in agriculture.

  Useful solid or liquid carriers include: ammonium salts and ground natural rocks such as kaolin, clay, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth, and ground synthetic rocks such as fine silica, alumina And natural or synthetic silicates, resins, waxes, solid fertilizers, water, alcohols, especially butanol, organic solvents, mineral and vegetable oils, and derivatives thereof. Combinations of such carriers can also be used.

  Suitable solid excipients and carriers include inorganic particles having an average particle size between 0.005 and 20 μm, preferably between 0.02 and 10 μm, such as carbonates, silicates, sulfates And oxides, such as ammonium sulfate, ammonium phosphate, urea, calcium carbonate, calcium sulfate, magnesium sulfate, magnesium oxide, aluminum oxide, silicon dioxide, so-called fine silica, silica gel, natural or synthetic silicates and alumo Examples include silicates and vegetable products such as cereal flour, wood powder / sawdust and cellulose powder.

  Useful solid carriers for granules include: natural rocks that have been crushed and sized, such as calcite, marble, pumice, sepiolite, dolomite, and synthetic granules of inorganic and organic coarse particles, and also organic materials Granules such as sawdust, coconut husk, corn cob and tobacco petiole are included.

  Useful liquefied gas extenders or carriers are liquids that are gaseous at standard temperatures and under standard pressures, such as aerosol propellants such as halogenated hydrocarbons, and also butane, propane, nitrogen And carbon dioxide.

  In formulations, tackifiers such as carboxymethylcellulose, and natural and synthetic polymers in powder, granule or latex form such as gum arabic, polyvinyl alcohol and polyvinyl acetate, or natural phospholipids such as cephalin and lecithin As well as synthetic phospholipids. Further additives can be mineral and vegetable oils.

  If the extender used is water, it is also possible to use, for example, an organic solvent as auxiliary solvent. Useful liquid solvents are essentially: aromatic compounds such as xylene, toluene or alkylnaphthalene, chlorinated aromatic compounds and chlorinated aliphatic hydrocarbons such as aliphatic hydrocarbons such as chlorobenzene, chloroethylene or dichloromethane, For example, cyclohexane or paraffin, such as mineral oil fractions, mineral oils and vegetable oils, alcohols such as butanol or glycol, and ethers and esters thereof, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, such as dimethyl solvents Such as formamide and dimethyl sulfoxide, and also water.

  The composition according to the invention may additionally comprise further components, such as surfactants. Useful surfactants are emulsifiers and / or foam formers, dispersants or wetting agents with ionic or nonionic properties, or combinations of these surfactants. Examples of these are polyacrylic acid salts, lignosulfonic acid salts, phenolsulfonic acid or naphthalenesulfonic acid salts, polycondensates of ethylene oxide with fatty alcohols, with fatty acids, or with fatty amines, substituted phenols. (Preferably alkylphenol or arylphenol), salts of sulfosuccinates, taurine derivatives (preferably alkyl taurates), polyethoxylated alcohols or phosphates of phenol, fatty esters of polyols, and sulfates, sulfonates and phosphates Compound derivatives such as alkyl aryl polyglycol ethers, alkyl sulfonates, alkyl sulfates, aryl sulfonates, protein hydrolysates, lignin sulfite effluents and A Le cellulose. The presence of a surfactant is necessary when one of the active ingredients and / or one of the inert carriers is insoluble in water and when the application is carried out in water. The proportion of surfactant is between 5 and 40% by weight of the composition of the invention.

  Suitable surfactants (adjuvants, emulsifiers, dispersants, protective colloids, wetting agents and adhesives) include all customary ionic and non-ionic substances, such as polyethoxylated ethoxylated nonylphenols, linear or branched alcohols. Alkylene glycol ethers, reaction products of alkylphenols with ethylene oxide and / or propylene oxide, reaction products of fatty acid amines with ethylene oxide and / or propylene oxide, as well as fatty acid esters, alkyl sulfonates, alkyl sulfates, alkyls Ether sulfates, alkyl ether phosphates, aryl sulfates, ethoxylated aryl alkyl phenols such as tristyryl-phenol-ethoxylates, and Sulfated or phosphated aryl alkylphenol - ethoxylates and - ethoxy - and - ethoxylated and propoxylated arylalkylphenols such propoxylates. Further examples are natural and synthetic water-soluble polymers such as lignosulfonates, gelatin, gum arabic, phospholipids, starches, hydrophobically modified starches and cellulose derivatives, especially cellulose esters and cellulose ethers, as well as polyvinyl alcohol, polyvinyl acetate, Polyvinyl pyrrolidone, polyacrylic acid, polymethacrylic acid and copolymers of (meth) acrylic acid and (meth) acrylic acid esters, as well as methacrylic acid and methacrylic acid esters neutralized with alkali metal hydroxides As well as condensates of optionally substituted naphthalene sulfonate and formaldehyde.

  Pigments such as inorganic pigments such as iron oxide, titanium oxide and Prussian blue, and organic dyes such as alizarin dyes, azo dyes and metal phthalocyanine dyes, and micronutrients such as iron, manganese, boron, copper, cobalt, molybdenum and Zinc salts can be used.

  Antifoaming agents that may be present in the formulation include, by way of example, silicone emulsions, long chain alcohols, fatty acids and their salts, as well as fluorinated organic materials and combinations thereof.

  Examples of thickeners are polysaccharides such as xanthan gum or bee gum, silicates such as attapulgite, bentonite as well as fine silica.

  Where appropriate, it is also possible for other additional components, such as protective colloids, binders, adhesives, thickeners, thixotropic substances, penetrants, stabilizers, scavengers, complexing agents to be present. . In general, the active ingredient can be combined with any solid or liquid additive customarily used for pharmaceutical purposes.

  The combinations or compositions according to the invention can be used as such or in the form of their formulations or the use forms prepared therefrom, depending on their respective physical and / or chemical properties, eg aerosols, capsules Suspensions, cold-fogging concentrates, warm-fogging concentrates, encapsulated granules, fine granules, flowable agents for seed treatment, ready-to-use solutions, powders, Emulsions, oil-in-water emulsions, water-in-oil emulsions, macro granules, fine granules, oil-dispersible powders, oil-miscible flowables, oil-miscible liquids, gas agents (under pressure), gas generating products ), Foam, paste, pesticide-coated seed, suspension formulation, suspoe Lotions, solutions, suspensions, wettable powders, soluble powders, soluble powders and granules, water-soluble and water-dispersible granules or tablets, water-soluble and water-dispersible powders for seed treatment In the form of wettable powders, natural and synthetic substances impregnated with active ingredients, and also microencapsulates in polymeric substances and in coating materials for seeds, and also ULV cold and hot fumes Can be used.

  The compositions of the present invention are not only formulations that are already ready for use and can be applied to plants or seeds using suitable equipment, but also commercial concentrates that must be diluted with water before use. Include. Conventional applications are, for example, dilution in water and subsequent spraying of the resulting spray solution, application after dilution in oil, direct application without dilution, seed treatment or soil application of granules. .

  The combinations, compositions and formulations according to the invention are generally between 0.05 and 99% by weight, between 0.01 and 98% by weight, preferably between 0.1 and 95% by weight, more preferably Contains between 0.5 and 90% by weight of active ingredient, most preferably between 10 and 70% by weight. For special applications, for example for the protection of wood and derived timber products, the combinations, compositions and formulations according to the invention are generally between 0.0001 and 95% by weight, preferably between 0.001 and 60. Contains between% by weight of active ingredient.

  The active ingredient content in the application forms prepared from the formulations can vary within wide limits. The concentration of the active ingredient in the application form is generally between 0.000001 and 95% by weight, preferably between 0.0001 and 2% by weight.

  The mentioned preparations are in a manner known per se, for example with the active ingredient being at least one conventional bulking agent, solvent or diluent, adjuvant, emulsifier, dispersant and / or binder or fixative, wetting agent, water repellent Agents, if appropriate desiccants and UV stabilizers, and if appropriate dyes and pigments, antifoams, preservatives, inorganic and organic thickeners, adhesives, gibberellins, and also further processing aids, and It can also be prepared by mixing with water. Depending on the formulation type to be prepared, further processing steps are required, eg wet grinding, dry grinding and granulation.

  The combinations or compositions according to the invention can be used directly or in their (commercial) formulations and in the use forms prepared from these formulations, with other (known) active ingredients such as insecticides, attractants. , Sterilants, bactericides, acaricides, nematicides, fungicides, growth regulators, herbicides, fertilizers, safeners and / or information chemicals and the like.

  The treatment of the present invention on plants and plant parts using the combination or composition can be carried out directly or by action on the surroundings, habitat or storage space, by conventional treatment methods, e.g. immersion, spraying, atomization, Irrigation, transpiration, dusting, fogging, fullcasting, foaming, application, spreading-on, irrigation (irrigation), by drip irrigation and especially in the case of breeding materials In the case of seeds, it can also be carried out by dry seed treatment, wet seed treatment, slurry treatment, shell formation, coating with one or more coatings, and the like. It is also possible to develop the combination or composition by the micro method, or to inject the combination or composition preparation or the combination or composition itself into the soil.

Plant / Crop Protection The combination or composition of the present invention has strong microbicidal activity and can be used in crop protection and material protection for the control of harmful microorganisms such as phytopathogenic fungi and bacteria .

  The invention also relates to a method for controlling harmful microorganisms characterized in that the combination or composition of the invention is applied to phytopathogenic fungi, phytopathogenic bacteria and / or their habitat.

  Fungicides can be used for the control of phytopathogenic fungi in crop protection. They are characterized by outstanding potency against a broad spectrum of phytopathogenic fungi, and these phytopathogenic fungi include soil-borne pathogens, especially Plasmophorophycetes, Peronosporomycetes (Syn. Oomycetes) (Omycetes)), Chytridiomycetes, Zygomycetes, Ascomycetes, Basidiomycetes (Deuteromycetes) and Deuteromycetes. impfecti)). Some fungicides have osmotic activity and can be used as leaf, seed dressing or soil fungicides in plant protection. Furthermore, they are suitable for combating fungi, especially fungi that parasitize the roots of wood or plants.

  Bactericides are used in crop protection in the fields of Xanthomonasaceae, Pseudomonadaceae, Rhizobaceaceae, Enterobacteraceae and Corynebacterium terecetoacetaceae. Can be used to control

Non-limiting examples of fungal pathogens that can be treated according to the present invention include the following:
Diseases caused by powdery mildew pathogens, for example, Blumeria species, such as Blumeria graminis; Podsphaera sp., Such as Species (Sphaerotheca species), for example, Sphaerotheca friginea; Uncinula species, for example, Uncinula necator;
Diseases caused by rust disease pathogens, for example, Gymnosporangium species, such as Gimnosporangium sabinae; Hemileis species such as Hemirea spp. (Hemileia vastatrix); Phakopsora species (e.g. Phacosora pachiridi); Phacosora peciliae (Phocosora peciliae); e), P.I. P. triticina, P. P. graminis or P. graminis P. striformis; caused by Uromyces species, such as Uromyces appendiculatus;
Diseases caused by pathogens from the group of Omycetes, such as Albugo species, such as Algubo candida; Bremia species, such as Bremi lacte Peronospora species, such as Peronospora pisi or P .; P. brassicae; Phytophthora species; eg, Phytophthora infestans; Plasmopara species; eg, Plasmopara pistula p. species, such as Pseudoperonospora humuli or Pseudoperosporum cubensis; Phythium species, Phythium sp. Due to timum);
Leaf blotch disease and leaf wilt disease, such as Alternaria species, such as Alternaria solani, cercospora sp, C For example, Cercospora beticola; Cladiosporium species, such as Cladiosporium cucumulinum; Birth forms: Drechslera, Syn: Synonymous with Helminthosporum, Cochliobolus miyathaneus; Choletotricum species Cycloconium species, such as Cycloconium oleaginum; Diaporthe species, such as Diaporthe citri; Elsinoe species ), E.g. Elsinoe fawcettii; Gloeosporium species, e.g., Gloeosporium laeticolol; Glomerella spp. ); Guinardia species, such as Guinardia bidwelli; Leptosperia species, such as Leptosperia Leptosphaelia, ptosphaeria nodorum); Magnaporthe spp (Magnaporthe species), for example, Magnaporthe grisea (Magnaporthe grisea); Microdochium species (Microdochium species), for example Microdochium nivale (Microdochium nivale); Mikosufaerera species (Mycosphaerella species), e.g. Mikosufaerera-Guraminikora (Mycosphaerella gramicola), M.M. Arachidicola and M. arachidicola M. fijiensis; Phaeosphaeria species, such as Phaeosphaeria nodrum; Pirenophora species, Pelenophora species, such as Pelenophora species Pyrenophora tritici repentiis; Ramularia species, such as Ramularia collo-cygni, Ramularia sp. (Rumularia sp.) For example, Rhynchosporium secalis; Septoria species, such as Septoria aphi, Septoria lycopersi, Tula; incarnat); due to Venturia species, such as Venturia inaequalis;
Root and stem diseases, such as Corticium species, such as Corticium graminearum; Fusarium species, such as Fusarium esporum sp. For example, caused by Gaumanomyces graminis; Rhizoctonia species, such as Rhizoctonia solani, etc .; Caused by (Sarocladium oryzae); caused by Sclerotim disease, eg, Sclerotium oryzae; Tapesia species, eg, Tapesia opiella; Thielabiopsis species), for example, caused by Thielabiopsis basicola;
Diseases of ear and panicles (including corn cobs) such as Alternaria spp., Eg Alternaria spp .; Aspergillus species, eg Aspergillus flavus ); Cladosporium species, such as Cladosporium cladosporoides; Claviceps species, such as Clavicepureza spp. Kumorumum (Fusarium culmorum); Gibber Gibberella species, such as Gibberella zeae; Monographella species, such as Monographella nivalis; or Tri, um or Sep, d. What to do;
Diseases caused by smut fungi, such as Sphacerotheca species, such as Sfaceloteca reliana; Tilletia species, such as Tileti caries Controversa; Urocystis species, such as Urocystis occulta; Ustylago species, such as Ustilago, Nuda, Ustila Due to N. trida (U. nuda tritici);
Spoilage of fruits, such as Aspergillus species, such as Aspergillus flavus; Botrytis species, such as Botrytis cinerea; Botrytis cinerea; Expansam (Penicillium expansum) and P. P. purpurogenum; Sclerotinia species, such as Sclerotinia sclerotiorum; Verticillium species, such as Verticillium sp.
Seed and soil mediated corrosion, mold, wilt, rot and damping-off, eg caused by Alternaria species, eg Alternaria brassicicola; Aphanomyces Genus Species (Aphanomyces species), for example, Aphanomyces eutices; for example, Ascochita species, for example, the genus Ascochite speris; Aspergillus flavus caused by Lavus; caused by Cladosporium species, such as Cladosporium herbarum; Cochliobolus species, such as Cochliobols soribas Conidia form: Drechslera, Bipolaris: synonymous with Helminthosporum); Colletotrichum species, eg, Coltotrichum cochlet; Fusarium Species (Fusarium species), such as those derived from Fusarium culmorum; Gibberella species, such as those from Gibberella zeae; • Caused by Macrophomina phaseolina; Monographella species, such as Monographella nivariis; Penicillium species, such as Penicillium sp. caused by Lillium expansum; caused by Forma species, such as Phoma lingam; Phomopsis species, eg caused by Phomopsis sojae; Phytophthora species, for example Phytophthora species; Pyrenophora species, for example Pyrenophora species, Pyrenophora species For example, Piliclaria ori Caused by Pyricularia oryzae; Phythium species, such as Pythium ultimum; Rhizotonia species, such as Rhizotonis Rhizopus species, for example, Rhizopus oryzae; Sclerotium species, for example, Sclerotium sp. ), Eg Septoria Nodrum (S due to Eptoria nodorum; from Typhula species, such as Typhula incarnata; from Verticillium species, such as from Verticillium dahlia;
Cancer disease, gallbladder and witches' room, such as those caused by Nectria species, such as Nectria galligena;
Wilt disease, for example, caused by Monilinia species, such as Monilinia laxa;
Caused by leaf blister disease or leaf curl disease, eg, Exobasidium species, eg, Exobasidium vexans;
Taphrina species, for example, Taphrina deformans;
Degenerative diseases of woody plants, such as Esca disease, for example, Phaemonella clamidospora, Phaeoacremonium aleophilum; Eypapa back, eg due to Eutypa lata; Ganoderma disease, eg due to Ganoderma boninense; Due to Gidoporusu-Rigunosasu (Rigidoporus lignosus);
Flower and seed diseases, such as those caused by Botrytis species, such as Botrytis cinerea;
Diseases of plant tubers, such as Rhizoctonia species, such as Rhizoctonia solani; Helminthosporum species, such as Helminthorium suloni ;
Root nodules, such as those resulting from Plasmodiophora species, such as Plasmodifora brassicae;
Diseases caused by bacterial pathogens, such as Xanthomonas species, such as Xanthomonas campestris pv. Oryzae; Pseudomonas species, Pseudomonas species, Pseudomonas species pv. lacrymans); derived from Erwinia species, such as Erwinia amylovara.

Examples of phytopathogenic bacteria in apple, banana, citrus, kiwi, melon, peach, pear, pineapple, pomegranate, pomegranate, cabbage, cauliflower, cucumber, cucurbitaceae, tomato, potato, wheat, rice and soybean Is
Acidoborax avena subsp. Citrulli, Agrobacterium tumefaciens (Agrobacterium tumefaciens), Aferanchoides fragiles (Aphelanchoides fragilis fragiles) ), Burkholderia glumae, Candidatus Liberabacterium spec., Clavibacter michiganensis, Krabibacter sect Scan subspecies Mishiganenshisu (Clavibacter michiganensis subsp.michiganensis), Krabi Arthrobacter Mishiganenshisu subspecies Teserariusu (Clavibacter michiganensis subsp.tessellarius), Krabi Arthrobacter Mishiganenshisu subspecies Sependonikusu (Clavibacter michiganensis subsp.Sepedonicus), Krabi Arthrobacter Mishiganenshisu subspecies Neburasukenshisu ( Clavibacter michiganensis subsp. Nebraskensis), Clavibacter iranixus, Clavibacter tritici Corynebacterium fasciens, Corynebacterium fracfaciens pathogenic fractum faciens (Corynebacterium faccumfaciens pv. Flaccumfaciens) (Corynebacterium michiganense pv. Tritici), Corynebacterium michiganense pathogenic type Nebraskense (Cornebacterium michiganense pv. Nebraskense), Corynebacterium sepedonic (Corynebacter) rium sepedonicum), Kurt Corynebacterium fracture-time tumefaciens pathogenic type fracture-time tumefaciens (Curtobacterium flaccumfaciens pv. flaccumfaciens), Enterobacter dissolvens, Erwinia subspecies, Erwinia amylovora, Erwinia anorawina Atroceptica (Erwinia carotovora subsp. Atropeptica), Erwinia carotovora subsp. Carotovora (Erwinia carotovora subsp. Kurisansemi pathogenic type Zeae (Erwinia chrysanthemi pv.Zeae), Erwinia Jisorubensu (Erwinia dissolvens), Erwinia herbicola (Erwinia herbicola), Erwinia Rapontiku (Erwinia rhapontic), Erwinia Sutewaruti (Erwinia stewartiii), Erwinia Torakeifira (Erwinia tracheiphila ), Erwinia uredovora, Pantoea agglomerans, Pectobacterium carotovorum, Pectobacter carotovorum Beam subspecies Atorosepuchikumu (Pectobacterium carotovorum subsp.atrosepticum), Baek Doo Corynebacterium Karotoborumu subspecies Karotoborumu (Pectobacterium carotovorum subsp.carotovorum), Baek Doo Corynebacterium Kurisansemi (Pectobacterium chrysanthemi), Pseudomonas Andro Pogo varnish (Pseudomonas andropogonis), Pseudomonas Abenae subspecies Abenae (Pseudomonas avenae subsp. Avenae), Pseudomonas corrugata (Pseudomonas corrugata), Pseudomonas fluoresence (Pseudomonas fluo) rescens), Pseudomonas glumae, Pseudomonas fuscovaginae, Pseudomonas al pseudomonas v. marginalis), Pseudomonas shoe de alkali monocytogenes (Pseudomonas pseudoalcaligenes), Pseudomonas shoe de alkali monocytogenes subspecies Shitoruri (Pseudomonas pseudoalcaligenes subsp.citrulli), Pseudomonas Soranasearumu (Pseudomonas solanacearum), Pseudomonas syringae (Pseudomonas syringae), Pseudomonas syringae pathogenic type Akuchinidae ( Pseudomonas syringae pv. Actinidae), Pseudomonas syringae pv. Atrofaciens, Pseudomonas Vinegar syringae pathogenic type corona tumefaciens (Pseudomonas syringae pv.coronafaciens), Pseudomonas syringae pathogenic type Gurishinea (Pseudomonas syringae pv.glycinea), Pseudomonas syringae pathogenic type Rakurimansu (Pseudomonas syringae pv.Lachrymans), Pseudomonas syringae pathogenic type Makurikora (Pseudomonas syringae pv. Maculacola), Pseudomonas syringae pathogenic strifaciens (Pseudomonas syringae pv. Strafaciens), Pseudomonas syringae pathogenic syringae (Pseudomonas syringae) v. syringae) [Kiwi fruit is similarly damaged], Pseudomonas syringae pv. Rathaybacter tritici, Rhodococcus fascians, Spiroplasma kunkelii, Streptomyces sp. abiei), Streptomyces Sukabiesu (Streptomyces scabies), Streptomyces reeds disk mold es (Streptomyces acidiscabies), Streptomyces Taj disk mold es (Streptomyces turgidiscabies), the genus Xanthomonas species (Xanthomonas spp. ), Xanthomonas Akusonopodisu (Xanthomonas axonopodis), Xanthomonas Akusonopodisu pathogenic type citri (Xanthomonas axonopodis pv.citri), Xanthomonas Akusonopodisu pathogenic type Gurishinesu (Xanthomonas axonopodis pv.glycines), Xanthomonas Kamupesutorisu (Xanthomonas campestris), Xanthomonas Kamupesutorisu pathogenic Xanthomonas campestris pv. Armoracaie, Xanthomonas campestris pathogenic citrumello (Xanthomonas campestris pv. Citrulumelo), Xanthomonas campestris Pathogenic type citri (Xanthomonas campestris pv.citri), Xanthomonas Kamupesutorisu pathogenic type Gurishinesu (Xanthomonas campestris pv.glycines), Xanthomonas Kamupesutorisu pathogenic type Horukikora (Xanthomonas campestris pv.Holcicola), Xanthomonas Kamupesutorisu pathogenic type Marubasearumu (Xanthomonas campestris pv. Malvaacearum, Xanthomonas campestris pv. Musacearum, Xanthomonas campestris pv. Praun. Xanthomonas campestris pv. ), Xanthomonas campestris pv. Xanthomonas campestris pv. Oryzae, Xanthomonas fragaliae, Xanthomonas oryzae, Xanthomonas oryzae pathogenic oryzae (Xanthomonas oryzae) anthomonas oryzae pv. oryzae), Xanthomonas oryzae pv. Oryzicola, Xanthomonas translucens, Xanthomonas translucensus Xanthomonas translucens. fastidiosa, Acidborax avenae, Burkholderia sp., Burkholderia glumae, Candidas reverbacter t r spec.), Corynebacterium spp., Erwinia spec., Pseudomonas syringae, Pseudomonas syringae spp. Pseudomonas syringae pv. Glycinea), Pseudomonas syringae tomato (Pseudomonas syringae)
pv. tomato, Pseudomonas syringae pv. lacrymans, Streptomyces spp., Xanthomonas spp. Xanthomonas axonopodis pv.citri, Xanthomonas axonopodis pathogenic glycinez (Xanthomonas axonopodis pv. Glycines), Xanthomonas campestris disease, Xanthomonas campestris disease Xanthomonas campestris pv. Musacearum, Xanthomonas campestris pathogenic Pruni (Xanthomonas campestris pv.

  The following bacterial pests can be preferably controlled: Acidovorax avenae, Burkholderia sp., Burkholderia glmae, Candida terbium sp. roseptica), Erwinia carotovora subsp. carotobola, Erwinia chrysanthemia, Erwinia chrysanthemia, Erwinia chrysanthemia, Erwinia chrysanthemia. (Erwinia stewartii), Erwinia uredovora, Pseudomonas syringae, Pseudomonas syringae pathogenic actinidae tinidae), Pseudomonas syringae pv. glycinea, Pseudomonas syringae ps. (Streptomyces spp.), Xanthomonas spp., Xanthomonas axonopodis, Xanthomonas axonopodis pathogenic citrus (Xanthomonas axonopodis. citri), Xanthomonas Akusonopodisu pathogenic type Gurishinesu (Xanthomonas axonopodis pv.glycines), Xanthomonas Kamupesutorisu (Xanthomonas campestris), Xanthomonas Kamupesutorisu pathogenic type Musasearumu (Xanthomonas campestris pv.musacearum), Xanthomonas Kamupesutorisu pathogenic type Puruni (Xanthomonas campestris pv. pruni), Xanthomonas fragaliae and Xanthomonas translucens.

  The following bacterial pests can be preferably controlled in the following crops: Acidovorax avenae and / or Burkholderia glumae in rice, Candidaceae reverbacter species in citrus (Candidacus sp. tris) and / or Xanthomonas campestris pv. Burkholderia spec. And / or Xanthomonas translucens in cereals, Pseudomonas syringae, Pseudomonas siriae in tomatoes Ngae pathogenic tomatoes (Pseudomonas syringae pv. Tomato) and / or Xanthomonas campestris; Erwinia atroceptica, Erwinia caratobora and / or Streptomyces scabies.

The following diseases of soybean can be preferably controlled:
Fungal diseases of leaves, stems, pods and seeds, such as Alternaria leaf spot (Alternaria spp. Atlans tenuisima), anthrax (Colletotricum gloeosporides dematium varieties Colletotrichum gloeosporoides dematium var. Truncatum), brown spot (Septria glycines), Sercospora colek and cercospora lech (cercospora lech) Coreephora leaf blight (chonephora l af blight) (synonymous with Choanephora infundibulifera trisporah), dactuliophora leaf spore (dactiophora leaf spot) (Peronospora manshurica)), drechslera blight (Drechslera glycini), frogeye leaf spot (sorkospolerso j) Leptosphaerulina leaf spot (Leptosphaerulina trifolii), phyllostica leaf fot (phyrostica leaf cot) (phyrostica leaf pot) ) (Phomopsis sojae), powdery mildew (Microsphaera diffusa), Pyrenochaeta leaf fot (Pirenochaeta glyzo leaves) Spider web (Rhizoctonia aerial, foliage, and web blight) (Rhizoctonia solai (Rhizoctonia solai)), rust disease (Phakopsora pachymei phai, phasomosis (Sphaceroma glycines), stemphylium leaf blight ((Stemphylium botryosum)), ring spot disease (corynespora ol ss i) .

  Fungal diseases of the roots and stems, for example, black root rot (Caronectria crotalariae), anthracnose (charcoal rot) (Macrophomina, Macrophomina red) Fungus or Fusarium wilt, root rot and pod and border rot (fusarium blight or wilt, and pod and collar rot), Fusarium oxysporum (Fusarium oxysporum) Semitectum (Fusarium semitec) um), Fusarium equiseti), mycoletodiscus root rot (Mycoletodiscus terrestris), neocosmosposmospo ), Pod and stem blight (Diaporthe phaseolum), stem tanker (Diaporthe phaseolacorum, Diaporthe varoseorum. Phytophthora rot (Phytophthora megasperma), fallen leaf rot (Phialophora gregata), Phythium rotum Phythium aphanidermatum, Phythium irregulare, Phythium debaryanum, Phythium myriotium, Rotium rum rhizocto nia root rot, stem decay, and damping-off) (Rhizoctonia sola rot), sclerotia stem decay (Sclerotinia strorole selenium) (Sclerotinia rolfsii), Thielabiopsis root rot (Thieraviopsis basicola).

  The fungicidal mixture or composition of the present invention can be used for therapeutic or protective / prophylactic control of phytopathogenic fungi. The invention therefore also relates to therapeutic and protective methods for controlling phytopathogenic fungi by use of the mixtures or compositions of the invention, wherein the active ingredient or composition of the invention comprises seeds, plants or Applied to soil where plant parts, fruits or plants grow.

  The fact that the mixture or composition is well tolerated by the plants at the concentrations required to control plant diseases allows for the treatment of above-ground parts of plants, breeding rootstocks and seeds, and soil.

Plants According to the invention, all plants and plant parts can be treated. By plant is meant all plants and plant populations, such as desirable and undesired wild plants, cultivars and plant varieties, whether or not they can be protected by plant varieties or plant grower rights. Cultivars and plant varieties are produced by one or more biotechnology methods, such as doubled haploid, protoplast fusion, random and directed mutagenesis, use of molecular or genetic markers, or biotechnological methods and It can be a plant obtained by conventional breeding and breeding methods that can be aided or supplemented by genetic engineering methods. Plant parts mean all above-ground and underground parts and organs of the plant, such as shoots, leaves, flowers and roots, for example leaves, needles, stems, branches, flowers, fruit bodies, fruits and seeds. Similarly, roots, corms and rhizomes are listed. Crop and vegetative and reproductive propagation materials such as cuttings, corms, rhizomes, stems and seeds also belong to the plant part.

  The combination or composition of the invention increases the yield to protect plants and plant organs when well tolerated by plants, has favorable thermophilic animal toxicity, and well tolerated by the environment. In addition, it is suitable for improving the quality of harvested materials. They can preferably be used as crop protection compositions. They are usually active against sensitive and resistant species, as well as against all or several developmental stages.

  Plants that can be treated according to the present invention include the following main crop plants: corn, soybean, alfalfa, cotton, sunflower, Brassica oil seeds such as Brassica napus (as an example) Canola, rapeseed), Brassica rapa, B.I. B. juncea (e.g. mustard (field mustard)) and brassica carinata (e.g., Alaceacee sp.) (E.g. oil palm, coconut), rice, wheat, sugar beet, Sugar cane, oats, rye, barley, millet and sorghum, triticale, flax, nuts, grapes and vines, and various fruits and vegetables from various botanical classifications, for example Rosaceae sp. Examples include berries, such as apples and pears, as well as berries, such as apricots, cherries, almonds, plums and peaches, and berries, such as strawberries, raspberries, red currants and black currants. ), Ribesioidae sp., Walnut plant (Juglandaceae sp.), Birch plant (Betulaceae sp.), Uracaceae plant (Facacee, Fasaceae). Moraceae sp., Oleaceae sp. (Eg olive), scorpionaceae (actinidaceae sp.), Camphoraceae (Lauraceae sp.) (Eg avocado, cinnamon, camphor), Musaceae sp. (Example banana tree and planting), Rubiaceae plant (Rubiaceae sp.) (Example coffee), Camellia family (Theac) ae sp.) (example tea), Aceraceae plant (Sterculaeae sp.), Citrus family plant (Rutaceae sp.) (example lemon, orange, mandarin and grapefruit); Solanumae plant (Solanasae sp.) (example) Tomato, Potato, Pepper, Pepper, Eggplant, Tobacco), Lilyaceae sp., Asteraceae (Compositiae sp.) (Eg lettuce, artichoke and chicory-root chicory, endive or camo (Common chicory), etc., Umbelliferae sp. (For example, carrot, parsley, celery and celeriac), Cucurbitaceae (Cucurb) itaceae sp. ) (Eg cucumber-gherkin, pumpkin, watermelon, gourd and melon), leeks (Alliaceae sp.) (Eg leek and onion), cruciferae (Cruciferae sp.) (Eg white cabbage) , Red cabbage, broccoli, cauliflower, brussels sprouts, king beetle, kohlrabi, radish, horseradish, watercress and Chinese cabbage), leguminous plants (Leguminosae sp.) (Eg peanuts, peas, lentils and legumes-eg kidney beans and broad beans) ), Rhesaceae plants (Chenopodiaceae sp.) (For example, chard, feed beet, spinach, beetroot), flaxaceae (Linaceae sp.) (Casa as an example), Cannabeacea sp. (For example, cannabis), Mallow (For example, okra, cocoa), Papaveraceae (for example, poppy), Cyprus (for example) Asparagaceae) (asparagus as an example); plants and ornamental plants useful in gardens and forests such as turf, lawn, grass and Stevia rebaudiana; and in each case genetic modifications of these plants.

  Soybean is a particularly preferred plant.

In particular, the mixtures and compositions according to the invention are suitable for controlling the following plant diseases:
Albgo spp. (White rust), which is an ornamental plant, vegetable crop (eg A. Candida) and sunflower (eg A. tragopogonis) Alternaria spp. (Black spot disease, black blotch), which is a vegetable, rape (eg A. brassicola or A A. brassicae), sugar beet (eg A. tenuis), fruit, rice, soybean, and also potato (eg A. solani or A. alternata ( A. alterna a)) and tomatoes (eg A. solani or A. alternata), as well as Alternaria spp. (black head), Attached to wheat; Aphanomyces spp., Which is attached to sugar beet and vegetables; Ascochita spp., Which is exemplified by cereals and vegetables. A. tritici (Ascochita leaf blight) is associated with A. tritici per wheat. A. hordei attaches to barley; Bipolaris and Drechlera spp. (Teleomorph: Cochliobolus spp.), For example, leaf spot disease. (D. maydis) and B. zeicola) for corn, for example, glume blotch (B. sorokiniana) for cereals, for example B. B. oryzae attaches to rice and turf; Blumeria (formerly Erysiphe), Graminis (powder mildew), which is used in cereals (eg wheat or barley) Botryosphaeria spp. ("Slack Dead Arm Disease"), which attaches to grapes (for example, B. obtusa); Botrytis cinerea ( Botrytis cinerea (Teleomorph: Botryotinia fucheliana: Gray mold disease, gray rot)) And berries (especially strawberries), vegetables (especially lettuce, carrots, celeriac and cabbage), rape, flowers, grapes, forest crops and wheat (ear mold); Bremia lactucae ) (Downy mildew), which affects lettuce; Ceratocystis spp. (Syn. Ophiostoma) (blue fungus), for deciduous and coniferous trees, for example C. C. ulmi (Dutch elm disease) grows on elm; Cercospora spp. (Cereosspora let spot), which is corn (eg C. zeae-Meydis) (C. zeae-maydis)), rice, sugar beet (eg C. beticola), sugar cane, vegetables, coffee, soybean (eg C. sojina or C. koctyl (C. kikuchil) and rice; Cladosporium spp., which is an example for tomatoes (eg C. fulvum: tomato leaf mold) and cereals To C. C. herbarum (ear rot) attaches to wheat; Clavipes purpurea (ergot), attaches to cereals; Cochliobolus spp. ( Anamorph: Helminthosporium or Bipolaris (leaf spot), which is corn (e.g. C. carbonum), cereals (e.g. C. subtilis) sativus), anamorph: B. sorokiniana: bacterial blotch) and rice (eg, C. miyabeanus, anamorph: Colletotrichum spp. (Teleomorph: Glomerella) (Anthracnosis), which is cotton (for example, C. gossippi) Corn (e.g. C. graminicola: stem rot and anthracnosis), small soft fruit, potato (e.g. C. coccodes: wilt disease) )), Common bean (eg C. lindemuthianum) and soybean (eg C. truncatum); Corticium species (Cor ticium spp.), for example C.I. C. sasakii (sheath blight) attaches to rice; Corynespora casicola (leaf spot), which attaches to soybeans and ornamental plants; Cyclocolo c oni spp.), for example C.I. C. oleaginum attaches to olives; Cylindrocarpon spp. (Eg, grape tree disease or black foot disease, black foot disease, teleomorph: Nectria Netria or Neolectria spp.), Which are fruit trees, grapes (for example C. liriodendon); teleomorphs: Neolectria liriodendri, di ole sse Many ornamental trees; Dematophora (Teleomorph: Roselinia) · Necatrix (necatrix) (root / stem blight (root / stem rot)), which is attached to the soybeans; (. Diaporthe spp) Jiaporute species, D. Examples Phaseolum (stem disease) attaches to soybeans; Drechlera spp. (Syn. Helminthosporium), Teleomorph: Pirenophora cereals For example, barley (eg D. teres, net blotch) and wheat (eg D. tritici-repentis: DTR leaf spot) , Rice and lawn; Esca disease (deeback of grape, apoplexia), which is per grape, formitipolia ( ormitiporia) (syn. Ferinusu (Phellinus)) · Punkutata (punctata), F. Mejiteranea (F.mediterranea), Faeomoniera-Kuramidosupora (Phaeomoniella chlamydospora) (formerly faecium OR Cremophor iodonium chlamydosporum (Phaeoacremonium chlamydosporum)), Faye OR Cremophor iodonium-Areofiramu (Phaeoacremonium aleophilum) and / or bottoming Rios file area Obutsusa (Botryosphaeria obtusa Elsinoe spp., Which is composed of berries (E. pyri) and small fruits (E. veneta: anthracnosis) and Grapes (E. ampelina): charcoal Enthromaoma oryzae (Leaf smut), which affects rice; Epicoccum spp. (Black head), which Wheat; Erysiphe spp. (Powder mildew), which is sugar beet (E. betae), vegetables (eg E. pisi) It is found in cucumber species (eg E. cichoraceralum) and cabbage species such as rape (eg E. cruciferarum); Eutypa fata (eutypa) Eumorpha cancer or dieback, anamorphs: Cytosporina lata, syn. Libertella blepharis, which is found in fruit trees, grapes and many ornamental tree hills; Species (Exerohilum spp.) (Synonymous with Helminthosporia), which attaches to corn (eg E. turcicum); Fusarium spp. (Teleomorph: Giberella) )) (Wilt disease, stem and stem rot), which for various plants, for example F Graminealum or F. F. culmorum (root rot and silver-top) is applied to cereals (eg wheat or barley as an example), Oxysporum is applied to tomato, F. oxysporum. F. solani is applied to soybeans and F. solani. F. verticilioides attaches to corn; Gaeumnomyces graminis (takeall), which attaches to cereals (eg wheat or barley) and corn; Gibberella species (Gibberell) ), Which is associated with cereals (eg G. zeae) and rice (eg G. fujikuroi: Bakaana disease); Glomerella singulata This is for grapes, pears and other plants, G. G. gossypi is on cotton; grain staining complex, it is on rice; Guinardia bidwellii (black rot), on grapes; Gymnosporangium spp., For Rosaceae and juniper, by way of example Sabinae (pear rust) is a pear; Helmintosporium spp.
(Drechslera, Teleomorph: synonymous with Cochliobolus), which attaches to corn, cereals and rice; Hemirea spp. H. vastatrix (coffee leaf rust), which sticks to coffee; Isariopsis clavispora (syn. Cladosporia vitis, vines) Macrophomina phaseolina (synonymous with phaseoli) (root / stem rot), which affects soybeans and cotton; Microdochium (same as Fusarium) Nivale (pink snow mold), which is a cereal (eg wheat or orange as an example) Attached to wheat); microspheres file Ella Jifusa (Microsphaera diffusa) (powdery mildew (powdery mildew)), which is attached to soybeans;. Monirinia species (Monilinia spp), M. Examples L. laxa, M. et al. M. fructicola and M. fractica. Fructigena (blossom and twig blight), which attaches to the fruits and other Rosaceae; Mycosphaerella spp., Which is a cereal, banana, small soft For fruits and peanuts, as an example Graminicola (Anamorph: Septoria tritici, Septoria leaf blotch) in wheat, or in M. cerevisiae (Anamorph: Septoria tritici, Septoria leaf blotch). M. fijiensis (Sigatoka disease) attaches to bananas; Peronospora spp. (Downy mildew), which is an example of cabbage (P. brassicae)), rape (e.g. P. parasitica), bulbous plant (e.g. P. destructor), tobacco (P. tabacina)) and soybean (e.g. P P. manshurica; Phakopsora pachyrhizi and P. manschuricha. P. meibomiae (soybean rust), which affects soybeans; Fialophora spp., Which is exemplified by grapes (eg P. tracheophila and P. tetraspora) (P. tetraspora) and soybeans (eg P. gregata: stem disease); Fora lingam (root and stem rot) This is for rape and cabbage. P. betae (leaf spot) develops in sugar beet; Phomopsis spp., Which consists of sunflower, grapes (for example P. viticola: vine split disease (dead) -Arm disease)) and soybeans (eg stem cancer / stem blight: P. phaseolii, teleomorph: diaporte phaseolum); (Physodera maydis) (brown spot), which attaches to corn; Phytophthora spp. (Wilt disease, root, Leaf, stem and fruit rot (root, leaf, stem and fruit rot), which is a variety of plants such as pepper and cucumber species (eg P. capsici), soybean (eg P. capsici). Megasperma (P. megasperma), syn.P. sojae), potatoes and tomatoes (eg P. infestans, late blight and brown rot) And deciduous trees (eg P. ramorum, sudden oak death), etc .; Plasmodiophora brassicae (club-root) , Which is cabbage, rape, get to radish and other plants; (. Plasmopara spp) Plasmopara spp, P. Examples P. viticola (grape peronospora, downy mildew) is applied to grapes and P. vicicola (P. viticola). P. halstedii attaches to sunflower; Podosphaera spp. (Powder mildew), which is related to Rosaceae, hops, pears and small soft fruits, for example P . P. leukotrica attaches to apples; polymyxa spp., Which includes, for example, cereals such as barley and wheat (P. graminis), and sugar beet (P. bettae). P. betae)) and viral infections transmitted by them; Pseudocosporelella herpotriochoides (eyeespot) / stem break, teleomorphs: tapesial yallundae)), which attaches to cereals, eg wheat or barley; Pseudoperonospora (downy mildew (dow) ny mildew)), which is a variety of plants, for example P.I. P. cubensis is a cucumber species or P. cubensis. Humilii hops; Pseudopezicula trachephila (angular leaf scorch, anamorph Fialophora), vine genus; Rust disease), which is described for various plants by way of example P. triticina (wheat red rust), P. triticina. P. striformis (yellow rust), P. P. hordei (dwarf leaf rust), P. hordei. Graminis (black rust) or P. graminis P. recondita (rye red rust) is found in cereals such as wheat, barley or rye. Kuehnii is a sugarcane, for example, on asparagus (eg P. asparagi); Pyrenophora (anamorph: Drechslera), Tritici-repentis (reticis) Blight (specked leaf blotch)), which is per wheat P. teres (net blotch) is found in barley; Pyricularia spp. P. oryzae (Tereomorph: Magnaporthe grisea, rice blast) is about rice. P. grisea attaches to grass and cereals; Phythium spp. (Damping-off disease), which is lawn, rice, corn, wheat, cotton, rape, sunflower, sugar beet , Vegetables and other plants (eg P. ultimum or P. aphanidermatum); Rumaria spp. R. collo-cygni (Rumaria leaf and lawn spot disease / physical leaf spot) per barley, R. collo-cygni (Rumaria leaf and lawn spot disease / physical leaf spot). R. beticola attaches to sugar beet; Rhizoctonia spp., Which is related to cotton, rice, potato, lawn, corn, rape, potato, sugar beet, vegetables and various other plants, for example R. beticola. R. solani (root and stalk rot is rooted in soybean, R. solani (sheath blight) is in rice, or R. selearis (R. cerealis (sharp eyespot) on wheat or barley; Rhizopus stroonifer (soft rot) on strawberry, carrot, cabbage, grape and tomato; linkospo Rhynchosporium secalis (leaf spot), which is found in barley, rye and triticale; Sarocladium oryzae and S. athen S. attenuatum (sheath rot), which attaches to rice; Sclerotinia spp. (Stem rot or stem or white rot), which It attaches to vegetables and crops such as rape, sunflower (eg, Sclerotinia sclerotiorum) and soybean (eg, S. rolfsii); various species of Septoria spp. For plants, for example, S. glycines (leaf spot) is applied to soybeans, S. tritici (Septoria leaf blot disease). ch)) on wheat, S. (syn. Stagonospora) nodolum (leaf blotch) and leaf bloch on cereals; Uncinula ( syn.Erysiphe, necator (powder mildew, anamorph: Oidium tuckeri), which is associated with grapes; Setospaeria sppp. leaf spot), which is corn (for example, S. turcumum, syn. Helminthosporium turcumum). )) And turf; Sphacerotheca spp. ) (Head smut), which is corn, (for example, S. reiliana: kernel smut), millet and sugar cane; Sphaerotheca fuliginea (U. Disease (powder mildew), which attaches to cucumber species; Spongo
Sporaspora subterranea (powder scab), which is a disease of potatoes and transmitted by them; Stagonospora spp., For example cereals . S. nodorum (leaf blotch and glume blotch, teleomorph: Leptospherea [syn. Phaeosphaeria] Nodrum (nodrum) Syncytium endobioticum, which is found in potatoes (potato wart disease); Taphrina spp. T. deformans (curly-leaf disease) per peach, T. deformans. T. pruni (plum-pocket disease) attaches to plum; Thielabiopsis spp. (Black root rot), which is tobacco, pomegranate, For vegetable crops, soybeans and cotton, T. T. basicola (syn. Chalara elegans); Tilletia spp. (Bunt or slinking smut), for example cereals . T. tritici (syn. T. caries, wheat bunt) and T. tritici. T. controversa (dwarf bunt) attaches to wheat; Typhula incarnata (gray snow mold), which applies to barley or wheat Urocystis spp., For example U. O. occulta (flag smut), which attaches to rye; Uromyces spp. (Rust), which is a vegetable plant such as kidney bean (eg U. bean). Appendiculatus, syn.U. phaseolii, sugar beet (eg U.betae), etc .; Ustylago spp. (Loose scab) smut)), which includes cereals (eg U. nuda and U. avaenae), corn (eg U. maydis: corn smut) and It attaches to sugarcane; Venturia species (Ve turia spp. (scab), which is about apples (eg V. inaequalis) and pears, and Verticillium spp. (leaf and leaf wilt) shot wilt)), which is for various plants such as fruit trees and ornamental trees, grapes, small soft fruits, vegetables and crops, etc. V. dahliae is found on strawberries, rape, potatoes, tomatoes and the like.

  The mixtures and compositions according to the invention are particularly preferred for controlling the following plant diseases: Soybean diseases: Cercospora kikuchii, Elsinoe glycines, Diaporte faceolum var. sojae), Seputaria-Gurishinesu (Septaria glycines), Cercospora Sojina (Cercospora sojina), Phakopsora pachyrhizi (Phakopsora pachyrhizi), Phytophthora sojae (Phytophthora sojae), Rhizoctonia solani (Rhizoctonia solani), Korinesupora-Kashiikora (Cory espora casiicola) and Sclerotinia sclerotiorum (Sclerotinia sclerotiorum).

Plant Health According to the present invention, the combinations and compositions of the present invention are suitable for enhancing plant health.

  Plant health enhancement is defined below as a plant growth regulator as defined below, and as a plant strengthening / resistance inducing compound as defined below. It can be used to bring about such plant physiology and to increase yield in crops as defined below.

Plant Growth Modulation In some cases, the combinations or compositions of the present invention may be used as herbicides, safeners, growth regulators or agents that improve plant properties, or microbicides at certain concentrations or application rates. As an agent, for example as a fungicide, antifungal agent, fungicide, viricide (including compositions for viroids) or as a composition for MLO (mycoplasma-like organisms) and RLO (rickettsia-like organisms) You can also. The active ingredients of the combination or composition of the present invention intervene in plant metabolism and can therefore be used as growth regulators.

  Plant growth regulators can exert various effects on plants. The effect of the substance depends essentially on the time of application relative to the developmental stage of the plant and also the amount of active ingredient applied to the plant or their environment and the type of application. In each case, the growth regulator should have a particular desired effect on the crop plant.

  Plant growth regulating compounds can be used, for example, to inhibit vegetative growth of plants. Such inhibition of growth is therefore possible, for example in the case of grass, because it can reduce the frequency of mowing in ornamental botanical gardens, parks and sports facilities, on the roadside, at airports, or in fruit crops. Economically interesting. Also of significance is the inhibition of herbaceous and woody plant growth on the roadside and in the vicinity of pipelines or overhead lines, or in areas where quite generally vigorous plant growth is not desired.

  Also important is the use of growth regulators to inhibit the vertical growth of cereals. This reduces or eliminates the risk of plant lodging before harvesting. In addition, growth regulators can strengthen cocoons in the case of cereals, which also counters lodging. The use of growth regulators to shorten and strengthen cocoons allows for the deployment of larger amounts of fertilizer to increase yield without any risk of lodging in cereal crops.

  In many crop plants, inhibition of vegetative growth allows for denser planting and thus higher yields can be achieved on a soil surface basis. Another advantage of the smaller plants obtained in this way is that it is easier to grow and harvest crops.

  Inhibition of vegetative plant growth can also lead to increased yields because nutrients and anabolic products are more beneficial to flower and fruit formation than to the vegetative part of the plant.

  Often, growth regulators can also be used to promote vegetative growth. This is highly beneficial when harvesting vegetative plant parts. However, because more anabolic products are formed, promoting vegetative growth can also promote reproductive growth, which results in a greater or larger number of fruits.

  In some cases, increased yield can be achieved by manipulating plant metabolism without any detectable change in vegetative growth. In addition, growth regulators can be used to alter the composition of the plant, which can result in improved quality of the harvested product. For example, it is possible to increase sugar content in sugar beet, sugar cane, pineapple and citrus fruits, or increase protein content in soybeans or cereals. It is also possible to use growth regulators, for example to inhibit the degradation of desirable components before or after harvest, for example sugar degradation in sugar beet or sugar cane. It can also have a positive impact on the production or removal of secondary plant components. One example is stimulating latex flow in rubber trees.

  Under the influence of growth regulators, parthenofruits can be formed. In addition, it is possible to influence the sex of flowers. It is also possible to produce sterile pollen, which is of great importance in the breeding and production of hybrid seeds.

  The use of growth regulators can control plant branching. On the other hand, it is possible to promote the development of side buds by breaking the apical dominance, which can be highly desirable especially in the cultivation of ornamental plants and also in combination with growth inhibition. On the other hand, however, it is also possible to inhibit the growth of side buds. This effect is particularly interesting, for example, in tobacco cultivation or in tomato cultivation.

  Under the influence of a growth regulator, the amount of plant leaves can be controlled so that plant defoliation is achieved at a desired time. Such litter plays a major role in the mechanical harvesting of cotton but is also of interest for facilitating harvesting in other crops, for example in viticulture. Plant littering can also be done to reduce transpiration of the plant before transplanting.

  Growth regulators can also be used to regulate fruit dehiscence. On the other hand, it is possible to prevent fruit cleavage before ripening. On the other hand, in order to eliminate variation, it is also possible to encourage fruit dehiscence or even stop flower development ("decimation") in order to achieve the desired mass. Variation is understood to mean the characteristics of several fruit species that make yields vary greatly from year to year due to intrinsic causes. Finally, growth regulators can be used at harvest time to reduce the force required to separate the fruits in order to allow mechanical harvesting or facilitate manual harvesting. is there.

  Growth regulators can also be used to achieve faster or slower ripening of harvested material before or after harvesting. This is particularly advantageous because it allows optimal adjustment to market demands. Moreover, growth regulators can improve fruit color in some cases. In addition, growth regulators can also be used to focus maturity within a certain period of time. This establishes the requirements for a complete mechanical or manual harvest in a single operation, for example in the case of tobacco, tomato or coffee.

  By using growth regulators, in addition, the seeds or buds of the plant so that plants in the nursery, such as pineapples or ornamental plants, usually germinate, germinate or bloom at times when they do not tend to do so. It is also possible to affect the rest of the machine. In areas where frost is at risk, it may be desirable to delay seed sprouting or germination using growth regulators to avoid damage resulting from late frost.

  Ultimately, growth regulators can induce plant resistance to frost, drought or high soil salinity. This allows for the cultivation of plants in areas that are usually not suitable for this purpose.

Resistance Induction and Other Effects The combination or composition according to the invention also exhibits a strong enhancing effect in plants. They can therefore be used to mobilize plant defenses against attack by undesirable microorganisms.

  Plant strengthening (resistance-inducing) substances, in the context of the present invention, develop a high resistance to these microorganisms when the treated plant is subsequently inoculated with unwanted microorganisms, It is understood to mean a substance capable of stimulating the defense system of plants.

  The active compounds according to the invention are also suitable for increasing the yield of crops. In addition, they exhibit reduced toxicity and are well tolerated by plants.

Furthermore, in the context of the present invention, plant physiological effects include:
Abiotic stress tolerance, which is temperature tolerance, drought tolerance and recovery after drought stress, water use efficiency (correlated with reduced water consumption), flooding tolerance, ozone stress and UV tolerance, heavy metals, salt, pesticides ( Tolerance to chemical substances such as safeners.

  Biological stress tolerance, including improved fungal resistance and improved resistance to nematodes, viruses and bacteria. In the context of the present invention, biological stress tolerance preferably includes improved fungal resistance and improved resistance to nematodes.

  Increase plant growth, including plant quality and seed growth, stand failure reduction, appearance improvement, resilience improvement, greening effect improvement and photosynthetic efficiency improvement.

  Effects on plant hormones and / or functional enzymes.

Effects on growth regulators (promoters), which include earlier germination, better germination, improved development of root system and / or root growth, improved tillering ability, more productive tillers, and more Early flowering, plant height and / or biomass increase, stem shortening, shoot growth, number of grains / ear, number of ears / m ² , improved number of roots and / or flowers, increased harvest index, greater Leaves, fewer dead roots, stratification improvement, earlier ripening / early fruiting termination, uniform maturation, increased ripening duration, better fruiting termination, larger fruit / plant size, Includes sprouting resistance and lodging reduction.

Yield increase, which refers to total biomass per hectare, yield per hectare, grain / fruit weight, seed size and / or hectoliter weight, as well as improved product quality:
Size distribution (grain, fruit, etc.), uniform maturity, grain moisture, better crushing, better winemaking, better brewing, increased juice yield, harvestability, digestibility, sedimentation value, falling number , Improved sheath length, storage stability, improved fiber length / strength / uniformity, improved silage-fed animal milk and / or meat quality, improved processability for adaptation to cooking and frying;
In addition, improved fruit / grain quality, size distribution (grains, fruits, etc.), improved storage / shelf life, hardness / softness, flavor (aroma, texture, etc.), grade (size, shape, berries) Number), berries / fruits per bunch, crispness, freshness, wax coverage, frequency of physiological disturbances, color, etc.
Furthermore, an increase in the desired ingredients, eg protein content, fatty acids, oil content, oil quality, amino acid composition, sugar content, acid content (pH), sugar / acid ratio (Brix), polyphenol, starch content, nutritional quality, gluten Including content / index, energy content, flavor, etc .;
And in addition, there is a reduction in unwanted components, such as less mycotoxin, less aflatoxin, geosmin levels, phenolic aroma, laccase, polyphenol oxidase and peroxidase, nitrate content and the like.

Sustainable agriculture, which improves nutrient use efficiency, especially nitrogen (N) use efficiency, phosphorous (P) use efficiency, water use efficiency, transpiration, respiration and / or CO ₂ assimilation rate, better Including nodulation and Ca metabolism improvement.

  Delayed senescence, which is manifested in longer ripening periods, for example, leading to higher plant yields, longer green leaf coloration periods and hence plant physiology including color (greening), water content, dryness, etc. Includes functional improvements. Thus, in the context of the present invention, the application of certain active compound combinations of the present invention has been found to allow an extension of the green leaf area duration, which delays plant aging (aging). It was done. A major advantage for farmers is a longer ripening period that leads to higher yields. There is also an advantage for farmers based on the fact that the harvest time can be made larger and more flexible.

  The “sedimentation value” is a measure for the quality of the protein and describes the degree of sedimentation of the flour suspended in the lactic acid solution in a standard time interval according to zeleni (zeleny value). . This is taken as a measure of bread making quality. The expansion of the gluten fraction of the flour in the lactic acid solution affects the sedimentation rate of the flour suspension. Both higher gluten content and better gluten quality slow down settling and increase the zereni test value. The settling value of flour depends on the wheat protein composition and is most correlated with protein content, wheat firmness, and the volume of dish and oven loaf. The stronger correlation between loaf volume and zeleni sedimentation volume compared to SDS sedimentation volume may be due to protein content affecting both volume and zereni values (wherein “sediment number” is the protein's content). A measure of quality, which describes the degree of sedimentation of flour suspended in a lactic acid solution in a standard time interval according to zeleni (the zeleni value), which is taken as a measure of bread making quality. The expansion of the gluten fraction of the flour in lactic acid solution affects the settling rate of the flour suspension, both higher gluten content and better gluten quality both slow settling and increase the zereni test value. The settling value of flour depends on the wheat protein composition and is most correlated with protein content, wheat firmness, and the volume of dish and oven loaf. The stronger correlation between loaf volume and zeleni sedimentation volume may be due to the protein content affecting both volume and zereni values (Czech J. Food Sci. Vol. 21, No. 3: 91-96, 2000).

  In addition, the “falling number” referred to herein is a measure for the bread-making quality of cereals, especially wheat. The falling number test indicates that germination damage may have occurred. That means that changes to the physical properties of the starch portion of the wheat kernel have already occurred. In this, the falling number device analyzes the viscosity by measuring the resistance of the flour and water paste to the falling plunger. The time (in seconds) at which this occurs is known as the falling number. The falling number result is recorded as an indicator of enzyme activity in the wheat or flour sample, and the result is expressed in time as seconds. A high falling number (eg, over 300 seconds) indicates minimal enzyme activity and healthy quality wheat or flour. A low falling number (eg, less than 250 seconds) indicates significant enzyme activity and germinated damaged wheat or flour.

  The term “more developed root system” / “root growth improvement” means longer root system, deeper root growth, faster root growth, higher root dry / fresh weight, higher root volume, larger root surface area, greater Refer to root diameter, higher root stability, more root branching, higher root hair count, and / or more root tips and analyze root structure using preferred methods and image analysis programs (eg WinRhizo) Can be measured.

  The term “crop water use efficiency” refers technically to the amount of agricultural product per unit of water consumed, and economically to the value of the product (s) per unit of water consumed, By way of example, the yield per ha, the biomass of the plant, the mass of 1000 grains and the number of ears per m2 can be measured in units.

  The term “nitrogen efficiency” technically refers to the amount of agricultural product per unit nitrogen consumed, and economically the value of the product (s) per unit nitrogen consumed. , Reflecting uptake and utilization efficiency.

  Greening / color improvement and photosynthetic efficiency improvement as well as aging delay can be measured using well-known techniques such as the HandyPea system (Hanstech). Fv / Fm is a parameter that is widely used to indicate the maximum quantum efficiency of photosystem II (PSII). This parameter is widely considered to be a selective indicator of plant photosynthetic performance and typically achieves a maximum Fv / Fm value of about 0.85 in healthy samples. Lower values are observed when the sample is exposed to certain biological or abiotic stressors that reduce the ability of photochemical quenching of energy within PSII. Fv / Fm is expressed as the ratio of variable fluorescence (Fv) to maximum fluorescence value (Fm). The figure of merit is essentially a measure of the vitality of the sample (see, for example, Advanced Technologies in Soil Microbiology, 2007, 11, 319-341; Applied Soil Ecology, 2000, 15, 169-182).

  Greening improvement / color improvement and photosynthetic efficiency improvement, as well as aging delay, can also be measured by the net photosynthetic rate (Pn), eg chlorophyll content measurement by Ziegler and Ehle pigment extraction method, photochemical efficiency (Fv / Fm ratio) ) Measurement, shoot growth and determination of final root and / or canopy biomass, determination of tiller density, as well as determination of root mortality.

  In the context of the present invention, preference is given to improving plant physiological effects selected from the group comprising: increased root growth / more developed root system, improved greening, improved water use efficiency (water Correlation with reduced consumption), especially improved nutrient use efficiency, including improved nitrogen (N) use efficiency, delayed aging and increased yield.

  Among the increased yields, preference is given to improving the sedimentation value and falling number, as well as improving the protein and sugar content—especially in plants selected from the group of cereals (preferably wheat).

  Preferably, the novel use of the fungicidal combination or composition of the invention comprises: a) prophylactically and / or therapeutically controlling pathogenic fungi with or without resistance management; b ) Concerning combined use with at least one of increased root growth, improved greening, improved water use efficiency, delayed aging and increased yield. From group b) an increase in root system, water use efficiency and N use efficiency is particularly preferred.

Seed Treatment The present invention further includes a method of treating seed.

  The invention further relates to seed treated by one of the methods described in the previous paragraph. The seeds of the present invention are used in a method for protecting seeds from harmful microorganisms. In these methods, seed treated with at least one combination or composition of the invention is used.

  The combination or composition of the invention is also suitable for treating seed. Most of the damage to crop plants caused by pests is triggered by seed infection during storage or after sowing, and also during planting and after germination. This period is particularly critical since the roots and shoots of growing plants are particularly sensitive and even small damage can lead to plant death. Therefore, it is of great interest to protect seeds and germinating plants by using appropriate compositions.

  Control of phytopathogenic fungi by treating plant seeds has been known for a long time and is the subject of continuous improvement. However, seed treatment involves a series of problems that cannot always be solved satisfactorily. For example, it is desirable to develop a method for protecting seeds and germinating plants that eliminates, or at least significantly reduces, the additional development of a crop protection composition after planting or emergence of plants. Optimize the amount of active ingredient used to provide the best possible protection from attack by phytopathogenic fungi on seeds and germinating plants without damaging the plants themselves by the active ingredient used It is also desirable. In particular, the seed treatment method also takes into account the endogenous fungicidal properties of the transgenic plant in order to achieve optimal protection of the seed and the germinating plant while minimizing the consumption of the crop protection composition. Should.

  The invention therefore also relates to a method for the protection of seeds and germinating plants from attack by phytopathogenic fungi by treating the seeds with the composition of the invention. The invention also relates to the use of the composition according to the invention for the treatment of seed to protect the seed and the germinating plant from phytopathogenic fungi. The present invention further relates to seed treated with the composition of the present invention for protection from phytopathogenic fungi.

  Control of phytopathogenic fungi that damage plants after emergence is performed primarily by treating soil and above-ground parts of plants with crop protection compositions. Due to concerns regarding the potential impact of crop protection compositions on the environment and human and animal health, there are attempts to reduce the amount of active ingredient to deploy.

  One of the advantages of the present invention is that the unique osmotic properties of the combination or composition of the present invention is that the treatment of the seed with these active ingredients and compositions is not limited to the seed itself, but the resulting postemergence It means that plants are also protected from phytopathogenic fungi. In this way, immediate treatment at the time of sowing of the crop or immediately after it can be omitted.

  Likewise, the combination or composition of the invention can also be used in particular with transgenic seeds, in which case it is advantageous that plants growing from these seeds are capable of expressing proteins that act against pests. it is conceivable that. By treating such seeds with the combinations or compositions of the present invention, certain pests can be controlled only by the expression of proteins, such as insecticidal proteins. Surprisingly, in this case, a further synergistic effect can be observed, which further improves the effectiveness of protection against pest attack.

  The compositions according to the invention are suitable for protecting the seeds of any plant variety used in agriculture, in the greenhouse, in the forest or in horticulture and viticulture. Among other things, it includes cereals (such as wheat, barley, rye, triticale, sorghum / millet and oats), corn, cotton, soybeans, rice, potatoes, sunflowers, beans, coffee, beets (eg sugar beet and feed beets), peanuts Seeds of rape, poppy, olive, coconut, cocoa, sugar cane, tobacco, vegetables (such as tomatoes, cucumbers, onions and lettuce), turf and ornamental plants (see also below). The treatment of cereals (such as wheat, barley, rye, triticale and oats), corn and rice seeds is of particular significance. Particularly preferred are soybean seeds.

  Also, as described below, the treatment of transgenic seed with the mixture or composition of the present invention is particularly significant. This relates to seeds of plants that contain at least one heterologous gene that allows the expression of polypeptides or proteins with insecticidal properties. Heterologous genes in transgenic seeds include, for example, the genus Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, Clavibacter, and Clavibacter. It can originate from microorganisms of the species of Glomus or Gliocladium. The heterologous gene preferably originates from a Bacillus species, where the gene product is effective against European maize borer and / or Western corn rootworm. The heterologous gene is more preferably originated from Bacillus thuringiensis.

  In the context of the present invention, the combination or composition of the present invention is applied to the seed either alone or in a suitable formulation. Preferably, the seed is treated in a sufficiently stable state so as not to cause damage during the course of treatment. In general, seeds can be treated at any time between harvest and sowing. It is customary to use seeds that have been separated from the plant and from which the cobs, shells, stalks, skins, hairs or flesh have been removed. For example, it is possible to use seeds that have been harvested, purified and dried to reduce the water content to less than 15% by weight. Alternatively, it is also possible to use seeds that have been dried, for example treated with water and then dried again.

  When treating seeds, generally the amount of the composition of the present invention and / or the amount of further additives applied to the seed is selected so as not to harm the germination of the seed or damage the resulting plant. You have to be careful. This must be kept in mind especially in the case of combinations or compositions that may have phytotoxic effects at certain application rates.

  The combination or composition of the invention can be applied directly, i.e. without containing any other components and without being diluted. In general, it is preferred to apply the composition to the seed in the form of a suitable formulation. Suitable formulations and methods for seed treatment are known to those skilled in the art, for example, the following materials: US 4,272,417, US 4,245,432, US 4,808,430, US 5,876,739, US 2003 / 0176428A1, WO2002 / 080675, and WO2002 / 028186.

  Combinations or compositions that can be used in accordance with the present invention are converted into conventional seed dressing formulations such as solutions, emulsions, suspensions, powders, foams, slurries or other seed coating compositions, and also ULV formulations, etc. can do.

  These formulations are prepared in a known manner with the active ingredients as conventional additives such as customary bulking agents and also solvents or diluents, dyes, wetting agents, dispersing agents, emulsifiers, antifoaming agents, preservatives, diluting agents. Prepared by mixing with next thickener, adhesive, gibberellin and also water.

  Useful pigments that may be present in seed dressing formulations that can be used according to the present invention are all pigments customary for such purposes. Either a pigment that is barely soluble in water or a water-soluble dye can be used. Examples include rhodamine B, C.I. I. Pigment Red 112 and C.I. I. A dye known by the name of Solvent Red 1 is mentioned.

  Useful wetting agents that may be present in seed dressing formulations that can be used in accordance with the present invention are all substances that promote wetting and are conventionally used for the formulation of active pesticide ingredients. Preference is given to using alkyl naphthalene sulfonates such as diisopropyl or diisobutyl naphthalene sulfonate.

  Useful dispersants and / or emulsifiers that may be present in seed dressing formulations that can be used in accordance with the present invention are all nonionic, anionic and cationic that are conventionally used for the formulation of active pesticide ingredients. It is a dispersant. Preferably usable are nonionic or anionic dispersants or combinations of nonionic or anionic dispersants. Suitable nonionic dispersants include, among others, ethylene oxide / propylene oxide block polymers, alkylphenol polyglycol ethers and tristryrylphenol polyglycol ethers, and their phosphorylated or sulfated derivatives. Suitable anionic dispersants are in particular lignosulfonates, polyacrylates and aryl sulfonate / formaldehyde condensates.

  Antifoaming agents that may be present in seed dressing formulations that can be used according to the present invention are all suds suppressors that are conventionally used for the formulation of active pesticide ingredients. Silicone antifoaming agents and magnesium stearate can be preferably used.

  Preservatives that may be present in seed dressing formulations that can be used in accordance with the present invention are all substances that can be used for such purposes in agrochemical compositions. Examples include dichlorophen and benzyl alcohol hemiformal.

  Secondary thickeners that may be present in seed dressing formulations that can be used according to the present invention are all substances that can be used for such purposes in agrochemical compositions. Preferred examples include cellulose derivatives, acrylic acid derivatives, xanthan, modified clay and fine silica.

  Adhesives that may be present in seed dressing formulations that can be used according to the present invention are all customary binders that can be used in seed dressing products. Preferred examples include polyvinyl pyrrolidone, polyvinyl acetate, polyvinyl alcohol and tyrose.

  The gibberellins that may be present in the seed dressing formulation that can be used according to the invention can preferably be gibberellin A1, A3 (= gibberellic acid), A4 and A7; particularly preferred is the use of gibberellic acid. Gibberellins are known (see R. Wegler “Chemie der Pflanzenschutz- und Schadlingsbekampfungsmitttel,” Chemistry of the Crop Protection, 19), Vs., 40, Chemistry of the Crop Protection.

  The seed dressing formulations that can be used according to the present invention can be used directly or after prior dilution with water for the treatment of a wide range of different seeds such as seeds of transgenic plants. In this case, an additional synergistic effect may occur due to the interaction with the substance formed by the expression.

  All mixing units conventionally available for seed dressing, for the treatment of seeds with seed dressing formulations that can be used according to the invention or with preparations prepared therefrom by adding water Is useful. Specifically, the procedure for seed dressing is to place seeds in a mixer, add a specific desired amount of seed dressing formulation as it is or after pre-dilution with water, and the formulation is uniformly dispersed on the seed Mix everything until it is done. If appropriate, this is followed by a drying process.

Mycotoxin In addition, the treatment of the present invention can reduce the mycotoxin content in harvested material and food and feed prepared therefrom. As mycotoxins, but not exclusively, deoxynivalenol (DON), nivalenol, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxins, fumonisin, zearalenone, moniliformin, fusarin, diaseo Examples include diatotoxic sirpenol (DAS), bowbelisin, enniatin, fusaroproliferin, fusarenol, ochratoxin, patulin, ergot alkaloids and aflatoxins, which include, for example, the following fungi: Fusarium species such as F . F. accuminatum, F. acminatum. F. asiaticum, F. F. avenaceum, F. F. brookwellense, F. F. culmorum, F. F. graminearum (Giberbera zeae), F. F. equiseti, F. F. Fujikoroi, F. Fujikoroi F. musarum, F. musarum F. oxysporum, F. F. proliferatorum, F. F. poae, F. F. pseudograminearum, F. F. sambucinum, F. sambucinum F. sirpi, F. Semitectum, F. F. solani, F. F. sporotrichoides, F. F. langsethiae, F. F. subglutinans, F. F. tricinctum, F. Such as F. verticiliaides, and also Aspergillus sp. A. flavus, A. flavus Parasiticus, A. A. nomius, A. nomius. A. ochraceus, A. A. clavatus, A. A. terreus, A. Penicillium species such as A. versicolor, such as P. P. verrucosum, P. et al. P. viridicatum, P. P. citrinum, P. citrinum. EXPANSUM, P. P. claviforme, P. caviforme Claviceps species, such as C. roqueforti C. purpurea, C.I. C. fusiformis, C.I. C. paspali, C.I. Stachybotrys spec. And the like can be produced, such as Africana (C. africana).

Material Protection The combination or composition of the present invention can also be used in the protection of materials to protect industrial materials against attack and destruction by harmful microorganisms such as fungi and insects.

  In addition, the combination or composition of the present invention can be used as an anti-fouling composition alone or in combination with other active ingredients.

  Industrial materials are understood in the context of the present invention to mean non-biological materials prepared for industrial use. For example, industrial materials that are subject to protection from microbiological changes or destruction by the combination or composition of the present invention include adhesives, adhesives, paper, wallpaper and board / cardboard, textiles, carpets, leather, wood, It can be fibers and thin fabrics, paints and plastic products, cooling lubricants and other materials that can be infected or destroyed by microorganisms. Production plants and parts of buildings that can be damaged by microbial growth, such as cooling water circuits, cooling and heating systems and ventilation and air conditioning units, can also be mentioned within the scope of the material to be protected. Industrial materials within the scope of the present invention are preferably adhesives, sizing agents, paper and cardboard, leather, wood, paints, cooling lubricants and heat exchange fluids, more preferably wood.

  The combination or composition of the present invention may prevent detrimental effects such as decay, corrosion, discoloration, discoloration or mold formation.

  In the case of wood treatment, the combination or composition according to the invention can also be used against fungal diseases liable to develop on or inside timber. The term “timber” means all types of wood species, and all types of workpieces of this wood intended for construction, such as solid wood, high density wood, laminated wood and plywood. The method of treating timber according to the present invention mainly consists in contacting the combination or composition according to the present invention; this can be achieved, for example, by direct application, spraying, dipping, pouring or any other suitable means. Includes.

  In addition, the combination or composition of the present invention can be used to protect objects in contact with seawater or brackish water, especially hulls, screens, nets, buildings, mooring equipment and communication systems from fouling.

  The method of the invention for controlling harmful fungi can also be used for the protection of stored goods. Preserved products are understood to mean natural substances of plant or animal origin or processed products thereof that are of natural origin and for which long-term protection is desired. Preserved products of plant origin, such as plants or plant parts, such as stems, leaves, tubers, seeds, fruits, cereals, etc., are freshly harvested or (pre) dried, moistened, crushed, ground, pressed or roasted It can protect in the state after processing by roasting. Preserved products also include timber, both unprocessed, such as building timber, utility poles and fences, or in the form of finished products, such as furniture. Preserved products of animal origin are, for example, animal skin, leather, fur, hair. The combination or composition of the present invention may prevent detrimental effects such as decay, corrosion, discoloration, discoloration or mold formation.

  Microorganisms capable of degrading or altering industrial materials include, for example, bacteria, fungi, yeasts, algae and mucus organisms. The mixtures or compositions according to the invention are preferably fungi, in particular molds, wood-discoloring and wood-destroying fungi (Ascomycetes, Basidiomycetes, Deuteromycetes) and zygomycetes ( Act on Zygomycetes)) and on mucus organisms and algae. Examples include microorganisms of the following genera: Alternaria, such as Alternaria tenuis; Aspergillus, such as Aspergillus niger; Chaetomium, such as ketomicium Chaetomium globosum, etc .; Coniophora, eg, Coniophora puetana, etc .; Lentinus, eg, Lentinus tigrinus, etc. Polyporus genus (Poly orus), such as Polyporus versicolor; Aureobasidium, such as Aureobasidium pullulans; Sclerophyl, S, etc. Genus (Trichoderma), for example, Trichoderma viride, etc .; Ophiostoma spp., Ceratocystis spp., Humicolat spr. a spp.), Trichurus spp., Coriolus spp., Gloeophyllum spp., Pleurotus spp., Polya spp. ), Serpula spp., Tyromyces spp., Cladosporium spp., Paecilomyces spp., Mucor spp., Mucor spp. Genus (Escherichia), such as Escherichia coli; Pseudomonas, eg, pseudomonas Scan aeruginosa (Pseudomonas aeruginosa), and the like; Staphylococcus (Staphylococcus), for example Staphylococcus aureus (Staphylococcus aureus), etc., Candida species (Candida spp. ) And Saccharomyces spp., Such as Saccharomyces cerevisiae.

Antifungal activity In addition, the combinations or compositions of the invention also have a very good antifungal activity. They are especially against dermatophytes and yeasts, molds and biphasic fungi (eg against Candida species, eg C. albicans, C. glabrata, etc.) ), And Epidermophyton floccosum, Aspergillus sp. A. niger and A. niger Trichophyton species, such as A. fumigatus, such as T. fumigatus. Microsporon species such as M. tagrophytes, such as M. globules. M. canis and M. canis It has a very broad spectrum of antifungal activity against M. audouinii and the like. These lists of fungi in no way constitute a limitation of the fungal spectrum covered, but are merely exemplary in nature.

  The combinations or compositions of the invention can therefore be used in both medical and non-medical applications.

Genetically modified organisms As already mentioned above, it is possible to treat all plants and their parts according to the invention. In preferred embodiments, wild-type plant species and plant cultivars, or those obtained by conventional biological breeding methods, such as crossing or protoplast fusion, and portions thereof are treated. In further preferred embodiments, transgenic plants and plant cultivars (genetically modified organisms) and parts thereof obtained by genetic engineering methods combined with conventional methods, if appropriate, are treated. The terms “parts” or “parts of plants” or “plant parts” are explained above. More preferably, plants of plant cultivars that are commercially available or used are treated according to the present invention. Plant cultivars are understood to mean plants obtained by conventional breeding, by mutagenesis or by recombinant DNA technology, having a novel property (“trait”). They can be cultivars, varieties, biotypes or genotypes.

  The treatment method according to the invention can be used in the treatment of genetically modified organisms (GMO), for example plants or seeds. A genetically modified plant (or transgenic plant) is a plant in which a heterologous gene is stably integrated into the genome. The expression “heterologous gene” is essentially a gene supplied or constructed outside a plant that expresses the protein or polypeptide of interest when introduced into the nucleus, chloroplast or mitochondrial genome. Or down-regulate or silence other gene (s) present in the plant (eg, using antisense technology, co-suppression technology, RNA interference-RNAi-technology or microRNA-miRNA-technology) By singing is meant a gene that confers new or improved agronomic or other properties to the transformed plant. A heterologous gene located in the genome is also called a transgene. A transgene that is defined by its particular location in the plant genome is called a transformation or gene transfer event.

  Depending on the plant species or plant cultivars, their location and growth conditions (soil, climate, growth period, nutrition), the treatment according to the invention can also lead to an additive (“synergistic”) effect. . Thus, for example, reducing the application rate of active compounds and compositions that can be used according to the invention and / or broadening the activity spectrum and / or improving the activity, better plant growth, improved resistance to high or low temperatures. , Improved tolerance to drought or water or soil salinity, improved flowering performance, easier harvesting, accelerated ripening, higher yield, larger fruits, larger plant height, darker green leaf color, earlier Flowering, higher quality and / or higher nutritional value of the harvested product, higher fruit sugar concentration, better storage stability and / or processability of the harvested product are possible and are actually expected It exceeds the effect.

  At certain application rates, the combination or composition according to the invention may also have a strengthening effect in plants. They are therefore also suitable for mobilizing plant defense systems against attack by harmful microorganisms. This may be one of the reasons for enhancing the activity of the combination or composition according to the invention, for example against fungi, if appropriate. Plant strengthening (resistance-inducing) substances are used in the context of the present invention so that, when subsequently inoculated with harmful microorganisms, the treated plant presents a substantial degree of resistance against these microorganisms. It is understood to mean a substance or combination of substances that is capable of stimulating the defense system. In this case, harmful microorganisms are understood to mean phytopathogenic fungi, bacteria and viruses. Therefore, the combination or composition according to the invention can be used to protect plants against attack by the above mentioned pathogens for a certain period of time after treatment. The period during which the protection is effective generally ranges from 1 to 10 days, preferably from 1 to 7 days, after the plant has been treated with the active compound.

  Plants and plant cultivars that are preferably treated according to the present invention include all plants (generally obtained by breeding and / or biotechnological means) that have genetic material that imparts particularly advantageous and useful traits to these plants. Even).

  Plants and plant cultivars that are also preferably treated according to the invention are resistant to one or more biological stresses, i.e. the plants are resistant to harmful animals and harmful microorganisms, e.g. nematodes. Better protection against insects, ticks, phytopathogenic fungi, bacteria, viruses and / or viroids.

  Examples of nematodes or insect-resistant plants include, by way of example, US patent application Ser. Nos. 11 / 765,491, 11 / 765,494, 10 / 926,819, 10 / 782,020, 12 / 032,479, 10 / 783,417, 10 / 782,096, 11 / 657,964, 12 / 192,904, 11 / 396,808, 12/166 No. 253, No. 12 / 166,239, No. 12 / 166,124, No. 12 / 166,209, No. 11 / 762,886, No. 12 / 364,335, No. 11 / 763,947 No. 12 / 252,453, No. 12 / 209,354, No. 12 / 491,396, No. 12 / 497,221, No. 12 / 644,632, No. 12 / 646,004, 12/701, 58 No., No. 12 / 718,059, No. 12 / 721,595, are described in No. 12 / 638,591.

  Plants and plant cultivars that can also be treated according to the present invention are plants that are resistant to one or more abiotic stresses. Abiotic stress conditions include, for example, drought, low temperature exposure, heat exposure, osmotic stress, flooding, increased soil salinity, increased mineral exposure, ozone exposure, high light exposure, limited availability of nitrogen nutrients, Mention the limited availability of phosphorus nutrients, avoiding shade.

  Plants and plant cultivars that can also be treated by the present invention are plants characterized by enhanced yield characteristics. Yield increases in the plant include, for example, improved plant physiology, growth and development, such as water use efficiency, water retention efficiency, nitrogen use improvement, carbon assimilation, photosynthesis improvement, germination efficiency and It can be the result of accelerated aging and the like. In addition, improved plant composition (under stress and non-stress conditions) can affect yield, including, but not limited to, early flowering, hybrid seed production. For flowering control, seedling growth, plant size, internode number and distance, root growth, seed size, fruit size, pod size, pod or ear number, pod or ear The number of seeds per seed, the mass of seeds, the increase of seed ripening, the reduction of seed scattering, the reduction of pod dehiscence and the lodging resistance. Further yield traits include seed composition such as carbohydrate content, protein content, oil content and oil composition, nutritional value, reduction of anti-nutrient compounds, improved processability and better storage stability.

  Plants that can be treated according to the present invention are hybrid plants that have already developed heterosis, i.e. hybrid stress characteristics, that generally result in higher yields, vigor, health and resistance to biological and abiotic stresses. Such plants are typically made by crossing an inbred male sterile parent line (female parent) with another inbred male fertile parent line (male parent). Hybrid seed is typically harvested from male sterile plants and sold to growers. Male sterile plants can be produced at the time (eg, in the corn) by removal of the ears, ie, mechanical removal of the male reproductive organs (ie, male flowers), but more typically, male steriles are It is the result of genetic determinants within. In that case, and particularly when the seed is the desired product harvested from the hybrid plant, it is typically useful to ensure that male fertility is fully restored in the hybrid plant. This is achieved by ensuring that the male parent has an appropriate fertility-recovering gene capable of restoring male fertility in hybrid plants containing genetic determinants involved in male sterility. be able to. The genetic determinant of male sterility can be located in the cytoplasm. Examples of cytoplasmic male sterility (CMS) have been described, for example, in Brassica species (WO 92/05251, WO 95/09910, WO 98/27806, WO 05/002324, WO 06/021972 and US 6,229,072). ). However, male sterility genetic determinants can also be located in the nuclear genome. Male sterile plants can also be obtained by plant biotechnology methods such as genetic manipulation. A particularly useful means for obtaining male sterile plants is described in WO 89/10396, where, for example, ribonucleases such as barnase are selectively expressed in tapetum cells in the stamen. Fertility can then be restored by expression of a ribonuclease inhibitor, such as balster, in tapetum cells (eg WO91 / 02069).

  Plants or plant cultivars that can be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are herbicide-tolerant plants, ie plants that have been rendered tolerant to one or more predetermined herbicides. It is. Such plants can be obtained by genetic transformation or by selection of plants containing mutations that confer such herbicide tolerance.

  Herbicide-resistant plants are, for example, glyphosate-tolerant plants, ie plants made tolerant to the herbicide glyphosate or a salt thereof. Through different means, plants can be made resistant to glyphosate. For example, glyphosate-tolerant plants can be obtained by transforming plants with a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (EPSPS). Examples of such EPSPS genes include the AroA gene (mutant CT7) (Science 1983, 221, 370-371) of the bacterium Salmonella typhimurium, and the CP4 gene (Curr. Sp.) Of the genus Agrobacterium sp. (Topics Plant Physiol. 1992, 7, 139-145), a gene encoding EPSUN in Petunia (Science 1986, 233, 478-481), a gene encoding EPSPS in tomato (J. Biol. Chem. 1988, 263, 4280). -4289), or the gene encoding WOPS / Eleusine EPSPS (WO01 / 66704). It can also be a mutant EPSPS, for example as described in EP0837944, WO00 / 66746, WO00 / 66747 or WO02 / 26995. Glyphosate-tolerant plants can also be obtained by expressing a gene encoding the glyphosate oxidoreductase enzyme, as described in US 5,776,760 and US 5,463,175. Glyphosate-tolerant plants can also be obtained by expressing a gene encoding a glyphosate acetyltransferase enzyme, for example as described in WO02 / 036782, WO03 / 092360, WO2005 / 0125515 and WO2007 / 024782. Glyphosate-tolerant plants can also be obtained by selecting plants containing naturally occurring mutations of the above-mentioned genes, for example as described in WO01 / 024615 or WO03 / 013226. Plants expressing EPSPS genes conferring glyphosate tolerance are exemplified by US patent applications 11 / 517,991, 10 / 739,610, 12 / 139,408, 12 / 352,532, 11 / 312,866, 11 / 315,678, 12 / 421,292, 11 / 400,598, 11 / 651,752, 11 / 681,285, 11 / 605,824, 12 / 468,205, 11 / 760,570, 11 / 762,526, 11 / 769,327, 11 / 769,255, 11/943801 Or as described in 12 / 362,774. Plants containing other genes conferring glyphosate tolerance, such as decarboxylase genes, are exemplified by US patent applications 11 / 588,811, 11 / 185,342, 12 / 364,724, 11 / 185,560 or 12 / 423,926.

  Other herbicide resistant plants are, for example, plants made tolerant to herbicides that inhibit the enzyme glutamine synthase, such as bialaphos, phosphinotricin or glufosinate. Such plants are obtained by expressing a mutant glutamine synthase enzyme that is resistant to herbicide detoxification or inhibition, as described in US patent application Ser. No. 11 / 760,602 as an example. be able to. One such efficient detoxifying enzyme is an enzyme that encodes a phosphinothricin acetyltransferase, such as the bar or pat protein from Streptomyces species. Plants expressing exogenous phosphinothricin acetyltransferase are described, for example, in US Pat. Nos. 5,561,236; 5,648,477; 5,646,024; 5,273,894; 5,637,489; 5,276,268; 5,739,082; 5,908,810 and 7,112,665.

  Additional herbicide-tolerant plants are also plants that have been rendered resistant to herbicides that inhibit the enzyme hydroxyphenylpyruvate dioxygenase (HPPD). HPPD is an enzyme that catalyzes a reaction that converts para-hydroxyphenylpyruvate (HPP) to homogentisate. Plants that are resistant to HPPD inhibitors are naturally occurring resistances as described in WO 96/38567, WO 99/24585, WO 99/24586, WO 09/144079, WO 02/046387 or US 6,768,044. It can be transformed with a gene encoding a sex HPPD enzyme, or a gene encoding a mutant or chimeric HPPD enzyme. Resistance to HPPD inhibitors can also be obtained by transforming plants with genes encoding certain enzymes that allow the formation of homogentisate despite the inhibition of the wild type HPPD enzyme by HPPD inhibitors. Such plants and genes are described in WO99 / 34008 and WO02 / 36787. Plant tolerance to HPPD inhibitors also encodes an enzyme with prephenate deshydrogenase (PDH) activity in addition to the gene encoding the HPPD resistant enzyme, as described in WO 04/024928. It can also be improved by transforming the plant with the gene to be treated. Furthermore, by adding a gene encoding an enzyme capable of metabolizing or degrading the HPPD inhibitor, such as the CYP450 enzyme shown in WO2007 / 103567 and WO2008 / 150473, into the genome of the plant, the HPPD inhibitor Can be made more resistant to herbicides.

  Still further herbicide resistant plants are plants that have been rendered tolerant to acetolactate synthase (ALS) inhibitors. Known ALS inhibitors include, for example, sulfonylureas, imidazolinones, triazolopyrimidines, priimidinoxy (thio) benzoates and / or sulfonylaminocarbonyltriazolinone herbicides. Different mutations in the ALS enzyme (also known as acetohydroxyacid synthase, AHAS) are described, for example, in Channel and Wright (Weed Science 2002, 50, 700-712) as well as US Pat. No. 5,605,011. , 5,378,824, 5,141,870 and 5,013,659, known to confer tolerance to different herbicides and herbicide groups. Yes. Production of sulfonylurea resistant plants and imidazolinone resistant plants is described in US Pat. Nos. 5,605,011; 5,013,659; 5,141,870; 5,767,361; No. 5,304,732; No. 4,761,373; No. 5,331,107; No. 5,928,937 and No. 5,378,824; and in WO 96/33270. Have been described. Other imidazolinone resistant plants are also described, for example, in WO 2004/040012, WO 2004/106529, WO 2005/020673, WO 2005/093093, WO 2006/007373, WO 2006/015376, WO 2006/024351 and WO 2006/060634. Additional sulfonylurea and imidazolinone resistant plants are also described, for example, in WO 2007/024782 and US patent application 61/288958.

  Other plants that are resistant to imidazolinones and / or sulfonylureas are, for example, in US 5,084,082 for soybeans, in WO 97/41218 for rice, in US 5,773,702 and sugar beet in US 99/057965. As described in US 5,198,599 for lettuce or in WO 01/065922 for sunflower, by induced mutagenesis, by selection in cell culture in the presence of herbicides, or by mutant breeding Can be obtained.

  Other plants that are resistant to imidazolinones and / or sulfonylureas are, for example, in US 5,084,082 for soybeans, in WO 97/41218 for rice, in US 5,773,702 and sugar beet in US 99/057965. As described in US 5,198,599 for lettuce or in WO 01/065922 for sunflower, by induced mutagenesis, by selection in cell culture in the presence of herbicides, or by mutant breeding Can be obtained.

  Plants or plant cultivars that can also be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are resistant to attack by insect-resistant transgenic plants, ie certain target insects. Plant. Such plants can be obtained by genetic transformation or by selection of plants containing mutations that confer such insect resistance.

As used herein, an “insect resistance transgenic plant” includes any plant containing at least one transgene comprising a coding sequence encoding:
1) Insecticidal crystal protein from Bacillus thuringiensis or an insecticidal part thereof, such as listed by Crickmore et al. (1998, Microbiology and Molecular Biology Reviews, 62: 807-813), and Bacillus thuringi by Crickmore et al. (2005). Updated in toxin nomenclature, http: // www. lifesci. sussex. ac. Examples are Cry protein classes Cry1Ab, Cry1Ac, Cry1B, Cry1C, Cry1D, Cry1F, Cry2Ab, Cry3Ab or Cry3Bb, etc. Such a protein or an insecticidal part thereof (eg EP-A 1999141 and WO 2007/107302) or such a protein encoded by a synthetic gene as described in US patent application Ser. No. 12 / 249,016; ) A crystal protein from Bacillus thuringiensis that is insecticidal in the presence of a second other crystal protein from Bacillus thuringiensis or part thereof, or A binary toxin formed from, for example, Cry34 and Cry35 crystal proteins (Nat. Biotechnol. 2001, 19, 668-72; Applied Environm. Microbiol. 2006, 71, 1765-1774), or Cry1A or Cry1F protein and Cry2Aa Or binary toxins formed from Cry2Ab or Cry2Ae proteins (US patent application Ser. Nos. 12 / 214,022 and EP-A 2300618) etc .; or 3) hybrids containing portions of different insecticidal crystal proteins from Bacillus thuringiensis For example, insecticidal proteins such as the protein hybrid from 1) above or the protein hybrid from 2) above. , Cry1A produced by corn event MON89034. 105 protein (WO2007 / 027777); or 4) any one of the above 1) to 3), the target insect species acting and / or acting to obtain higher insecticidal activity against the target insect species In order to expand the range of and / or due to changes introduced into the coding DNA during cloning or transformation, some proteins, in particular 1 to 10 amino acids have been replaced by another amino acid, e.g. Cry3Bb1 protein in corn event MON863 or MON88017, or Cry3A protein in corn event MIR604; or 5) Insecticidal properties from Bacillus thuringiensis or Bacillus cereus Secreted proteins or insecticidal portions thereof, such as http: // www. lifesci. sussex. ac. uk / home / Neil_Crickmore / Bt / vip. eg, from the VIP3Aa protein class; or 6) insecticidal in the presence of a second secreted protein from Bacillus thuringiensis or Bacillus cereus, such as vegetative growth insecticidal protein (VIP) listed in html A secreted protein from Bacillus thuringiensis or Bacillus cereus, such as binary toxins formed from VIP1A and VIP2A proteins (WO94 / 21795); or 7) different secretion from Bacillus thuringiensis or Bacillus cereus A hybrid insecticidal protein comprising a portion from a protein, such as a hybrid of a protein in 1) above or a hybrid of a protein in 2) above; or 8) above ) To 7) to obtain higher insecticidal activity against the target insect species and / or to expand the range of target insect species that act and / or (still A protein in which some, especially 1 to 10 amino acids have been replaced by another amino acid, eg cotton events, due to changes introduced into the coding DNA during cloning or transformation (while encoding insecticidal proteins) VIP3Aa protein, etc. in COT102; or 9) formed from a secreted protein from Bacillus thuringiensis or Bacillus cereus, such as VIP3 and Cry1A or Cry1F, that is insecticidal in the presence of a crystal protein from Bacillus thuringiensis Ba Naritoxin (US Patent Application Nos. 61/126083 and 61/195019), or Binary Toxin formed from VIP3 protein and Cry2Aa or Cry2Ab or Cry2Ae protein (US Patent Application Nos. 12 / 214,022 and EP- A) 2300618), etc .; or 10) to obtain higher insecticidal activity against the target insect species and / or to expand the range of target insect species that act and / or (and A protein in which some, especially 1 to 10 amino acids are replaced by another amino acid due to changes introduced into the coding DNA during cloning or transformation (while encoding an insecticidal protein).

  Of course, the insect-resistant transgenic plant used herein also includes any plant containing a combination of genes encoding any one of the above classes 1 to 10 proteins. In one embodiment, the insect resistant plant contains more than one transgene encoding a protein of any one of the above classes 1 to 10, but this is different for different target insect species To broaden the range of target insect species that act when using proteins, or to act as insecticidal but different modes of action against the same target insect species, such as binding to different receptor binding sites within the insect This is to delay the development of insect resistance to plants by using different proteins with a mode.

  As used herein, an “insect resistance transgenic plant” is further expressed as described, for example, in WO2007 / 080126, WO2006 / 129204, WO2007 / 074405, WO2007 / 080127, and WO2007 / 035650. Any plant containing at least one transgene comprising a sequence that produces double stranded RNA that inhibits the growth of the harmful insect when ingested by the plant harmful insect is included.

Plants or plant cultivars that can also be treated according to the present invention (obtained by plant biotechnology methods such as genetic engineering) are resistant to abiotic stress. Such plants can be obtained by genetic transformation or by selecting plants containing mutations that confer such stress resistance. Particularly useful stress-tolerant plants include the following:
1) Expression and / or activity of poly (ADP-ribose) polymerase (PARP) gene in plant cells or plants as described in WO00 / 04173, WO2006 / 045633, EP-A1807519 or EP-A2018431 A plant containing a transgene that has the ability to reduce.

2) Plants containing a stress tolerance-enhancing transgene capable of reducing the expression and / or activity of the gene encoding PARG in plants or plant cells, as described in WO 2004/090140 as an example.

3) Nicotinamidase, nicotinate phosphoribosyltransferase, nicotinate mononucleotide adenyltransferase, nicotinamide, as described in EP-A 1794306, WO 2006/133827, WO 2007/107326, EP-A 1999263 or WO 2007/107326 as examples A plant containing a stress tolerance-enhancing transgene encoding a plant functional enzyme of the salvage biosynthetic pathway of nicotinamide adenine dinucleotide, including adenine dinucleotide synthase or nicotinamide phosphoribosyltransferase.

Plants or plant cultivars (obtained by plant biotechnology methods such as genetic engineering, etc.) that can also be treated according to the present invention can be used to change the quantity, quality and / or storage stability of harvested products and / or harvested products. Changes in the properties of certain components of these, such as:
1) Wild-type physicochemical properties, especially amylose content or amylose / amylopectin ratio, degree of branching, average chain length, side chain distribution, viscosity behavior, gel strength, starch granule size and / or starch granule morphology A transgenic plant that synthesizes modified starch that is altered compared to starch synthesized in a plant cell or plant and is therefore more suitable for special applications. The transgenic plant for synthesizing the modified starch is, for example, EP-A0571427, WO95 / 04826, EP-A0719338, WO96 / 15248, WO96 / 19581, WO96 / 27274, WO97 / 11188, WO97 / 26362, WO97 / 32985, WO97 / 42328, WO97 / 44472, WO97 / 45545, WO98 / 27212, WO98 / 40503, WO99 / 58688, WO99 / 58690, WO99 / 58654, WO00 / 08184, WO00 / 08185, WO00 / 08175, WO00 / 28052, WO00 / 77229, WO01 / 12782, WO01 / 12826, WO02 / 101059, WO03 / 071860, WO04 / 056999, WO05 / 30942, WO 2005/030941, WO 2005/095632, WO 2005/095617, WO 2005/095619, WO 2005/095618, WO 2005/123927, WO 2006/018319, WO 2006/103107, WO 2006/108702, WO 2007/009823, WO 00/22140, WO 62, 3862 WO2006 / 076023, WO02 / 034923, WO2008 / 017518, WO2008 / 080630, WO2008 / 080631, EP07090007.1, WO2008 / 090008, WO01 / 14569, WO02 / 79410, WO03 / 33540, WO2004 / 078983, WO01 / 19975, WO95 H.264 7, WO96 / 34968, WO98 / 20145, WO99 / 12950, WO99 / 66050, WO99 / 53072, US6,734,341, WO00 / 11192, WO98 / 22604, WO98 / 32326, WO01 / 98509, WO01 / 98509, WO2005 / 002359, US 5,824,790, US 6,013,861, WO 94/04693, WO 94/09144, WO 94/11520, WO 95/35026, WO 97/20936, WO 2010/012796, WO 2010/003701.

2) A transgenic plant that synthesizes non-starch carbohydrate polymers or synthesizes non-starch carbohydrate polymers that have altered properties compared to wild-type plants without genetic modification. Examples are plants producing polyfructose, in particular inulin and levan type polyfructose, as disclosed in EP-A 0 663 356, WO 96/01904, WO 96/21023, WO 98/39460 and WO 99/24593, WO 95/31553. Plants producing alpha-1,4-glucan as disclosed in US2002031826, US6,284,479, US5,712,107, WO97 / 47806, WO97 / 47807, WO97 / 47808 and WO00 / 14249, Plants producing alpha-1,6-branched alpha-1,4-glucan as disclosed in WO00 / 73422, for example WO00 / 47727, WO00 / 73422, EP0607731.7, US5 A plant for producing alternan, as disclosed in 908,975 and EP-A0728213.

3) Transgenic plants that produce hyaluronan as disclosed, for example, in WO2006 / 032538, WO2007 / 039314, WO2007 / 039315, WO2007 / 039316, JP-A2006-304779 and WO2005 / 012529.

4) As described in US patent application Ser. Nos. 12 / 020,360 and 61 / 054,026, for example, “high soluble solids content” “low hotness” (LP) and / or “ Transgenic plants or hybrid plants such as onions having characteristics such as “long-term storage” (LS).

Plants or plant cultivars that can also be treated according to the present invention (which can be obtained by plant biotechnology methods such as genetic engineering) are plants with altered fiber properties, such as cotton plants. Such plants can be obtained by genetic transformation or by selection of plants containing mutations that confer such changes in fiber properties, including:
a) Plants containing a modified cellulose synthase gene, such as cotton plants, as described in WO 98/00549.

b) Plants containing altered forms of rsw2 or rsw3 homologous nucleic acids, such as cotton plants, as described in WO 2004/053219.

c) Plants with increased expression of sucrose phosphate synthase, such as cotton plants, as described in WO01 / 17333.

d) Plants with increased expression of sucrose synthase, such as cotton plants, as described in WO 02/45485.

e) Protoplasmic communication in the base of fiber cells through, for example, fiber selective β1,3-glucanase down-regulation as described in WO 2005/015157 or as described in WO 2009/143395 Plants whose gate opening / closing timing has changed, such as cotton plants.

f) Plants having fibers with altered reactivity, such as cotton plants, through the expression of N-acetylglucosamine transferase genes such as nodC and chitin synthase genes, as described in WO 2006/136351, for example.

Plants or plant cultivars that can also be treated according to the present invention (which can be obtained by plant biotechnology methods such as genetic engineering) are plants that have altered oil profile characteristics, such as rape or related Brassica. Such as plants. Such plants can be obtained by genetic transformation or by selection of plants containing mutations that confer such oil profile property changes, including:
a) Plants producing oils with high oleic acid content, such as rape plants, as described in US 5,969,169, US 5,840,946 or US 6,323,392 or US 6,063,947 as examples Such.

b) Plants producing oils with low linolenic acid content, such as rape plants, as described in US 6,270,828, US 6,169,190 or US 5,965,755.

c) Plants producing oils with low levels of saturated fatty acids, such as rape plants, as described in US 5,434,283 or US patent application Ser. No. 12 / 668,303 by way of example.

  Plants or plant cultivars (which can be obtained by plant biotechnology methods such as genetic engineering) that can also be treated according to the present invention are plants that have altered seed shedding characteristics, such as rape or related Brassica. ) Plants. Such plants can be obtained by genetic transformation or by selection of plants containing mutations that confer such seed shattering characteristics changes, in US Patent Application Nos. 61 / 135,230, WO2009 / 068313 and WO2010 / 006732. And plants with delayed or reduced seed shedding, such as rape plants.

  Plants or plant cultivars (which can be obtained by plant biotechnology methods such as genetic engineering) that can also be treated according to the invention are post-translational, as described, for example, in WO2010 / 121818 and WO2010 / 145847 Plants with altered protein modification patterns, such as tobacco plants.

Particularly useful transgenic plants that can be treated by the present invention are transformation events or combinations of transformation events that are the subject of an application to the US Department of Agriculture (USDA) Animal and Plant Quarantine Station (APHIS) for exemption in the United States. It does not matter whether the application has been approved or is still pending. From time to time, this information is readily available from APHIS (4700 River Road, Riverdale, MD 20737, USA), for example on its Internet site (URL http://www.aphis.usda.gov/brs/not_reg.html). . As of the filing date of this application, the application for regulatory exclusion pending or authorized by APHIS contained the following information:
-Application: Application identification number. A technical description of the transformation event can be found in the individual application documents available from APHIS on the APHIS website, for example, by reference to this application number. These descriptions are incorporated herein by reference.

-Application extension: A reference to the previous application for which an extension is requested.

− Institution: Name of the entity that submitted the application.

-Regulated products: applicable plant species.

-Transgenic phenotype: A trait conferred to a plant by a transformation event.

-Transformation event or strain: the name of the event (s) for which exemption is being claimed (sometimes also referred to as strain (s)).

-APHIS Documents: Various documents issued by APHIS with respect to the application and can be charged to APHIS.

  Further particularly useful plants containing a single transformation event or a combination of transformation events are listed, for example, in databases from various national or regional regulators (eg http: //gmoinfo.jrc .It / gmp_browse.aspx and http://www.agbios.com/dbase.php).

Particularly useful transgenic plants that can be treated by the present invention are those that contain transformation events or combinations of transformation events, such as listed in databases for regulatory authorities in various countries or regions. , These include event 1143-14A (cotton, insect control, not deposited, described in WO 2006/128569); event 1143-51B (cotta, insect control, not deposited, in WO 2006/128570) Event 1445 (cotton, herbicide resistance, not deposited, described in US-A 2002-120964 or WO 02/034946); event 17053 (rice, herbicide resistance, PTA-9843) As WO2010 / 11 Event 17314 (rice, herbicide resistance, deposited as PTA-9844, described in WO2010 / 117735); event 281-24-236 (cotton, insect control- Herbicide tolerance, deposited as PTA-6233, described in WO 2005/103266 or US-A 2005-216969; event 3006-210-23 (cotton, insect control-herbicide tolerance, PTA-6233 Deposited, as described in US-A 2007-143876 or WO 2005/103266); Event 3272 (deposited as corn, quality trait, PTA-9972, in WO 2006/098952 or US-A 2006-230473 Listed Event 40416 (corn, insect control—herbicide resistance, deposited as ATCC PTA-11508, described in WO2011 / 075593); event 43A47 (corn, insect control—herbicide resistance, ATCC PTA) Event 5307 (Deposited as Corn, Insect Control, ATCC PTA-9561, Described in WO2010 / 0777816); Deposited as -11509, described in WO2011 / 075595; Event ASR -368 (bentgrass, herbicide tolerance, deposited as ATCC PTA-4816, described in US-A 2006-162007 or WO 2004/053062); event B16 (corn, herbicide tolerance, not deposited, It is described in S-A2003-126634); event BPS-CV127-9 (soybean, herbicide tolerance, NCIMB No. Event CE43-67B (deposited as cotton, insect control, DSM ACC2724, US-A2009-217423 or WO2006 / 128573, deposited as 41603, described in WO2010 / 080829); Event CE44-69D (cotton, insect control, not deposited, described in US-A 2010-0024077); Event CE44-69D (cotton, insect control, not deposited, in WO 2006/128571) Event CE46-02A (cotton, insect control, not deposited, described in WO 2006/128572); event COT102 (cotton, insect control, not deposited, US-A 2006) 130175 Or event COT202 (cotton, insect control, not deposited, described in US-A 2007-066786 or WO2005 / 054479); event COT203 (cotton, insect control) Event DAS40278 (cone, herbicide resistance, deposited as ATCC PTA-10244, described in WO2011 / 022469); Event DAS- 59122-7 (corn, insect control-herbicide resistance, deposited as ATCC PTA 11384, described in US-A 2006-070139); event DAS-59132 (corn, insect control-herbicide resistance, deposit) Is Not described in WO2009 / 100188); event DAS68416 (soybean, herbicide resistant, deposited as ATCC PTA-10442, described in WO2011 / 066384 or WO2011 / 0666360); event DP- 098140-6 (corn, herbicide tolerance, deposited as ATCC PTA-8296, described in US-A 2009-137395 or WO 2008/112019); event DP-305423-1 (soybean, quality trait, deposit Not described in US-A 2008-312082 or WO 2008/054747); event DP-32138-1 (cone, hybrid, deposited as ATCC PTA-9158, US- Event DP-356043-5 (soybean, herbicide tolerance, deposited as ATCC PTA-8287, described in US-A2010-0184079 or WO2008 / 002872) described in 2009-0210970 or WO2009 / 103049). Event EE-1 (brinjal, insect control, not deposited, described in WO2007 / 091277); event FI117 (corn, herbicide resistant, deposited as ATCC 209031) , US-A 2006-059581 or WO 98/044140); Event GA21 (corn, herbicide resistance, deposited as ATCC 209033, US-A 2005-086719 Event GG25 (corn, herbicide tolerance, deposited as ATCC 209032, US-A 2005-188434 or described in WO 98/044140); event GHB119 (cotton) , Insect control-herbicide resistance, deposited as ATCC PTA-8398, described in WO2008 / 151780); event GHB614 (cotta, herbicide resistance, deposited as ATCC PTA-6878, US- A2010-050282 or WO 2007/017186); Event GJ11 (corn, herbicide tolerance, deposited as ATCC 209030, US-A 2005-188434 or WO 98/044140) Event GM RZ13 (deposited as sugar beet, virus resistance, NCIMB-41601, described in WO2010 / 076121); event H7-1 (beet, herbicide resistance, NCIMB 41158 or (Deposited as NCIMB 41159, described in US-A 2004-172669 or WO 2004/074492); event JOPLIN1 (wheat, disease resistance, not deposited, described in US-A 2008-066402) Event LL27 (soybean, herbicide tolerance, deposited in NCIMB 41658, described in WO 2006/108674 or US-A 2008-320616); event LL55 (soybean, herbicide tolerance, N Deposited as CIMB 41660, described in WO 2006/108675 or US-A 2008-196127); event LLcotton 25 (cotton, herbicide resistance, deposited as ATCC PTA-3343, WO 03/013224 or US- Event LLRICE06 (rice, herbicide tolerance, deposited as ATCC-23352, described in US 6,468,747 or WO 00/026345); event LLRICE 601 (rice) , Herbicide tolerance, deposited as ATCC PTA-2600, described in US-A 2008-2289060 or WO 00/026356; event LY038 (corn, quality form , Deposited as ATCC PTA-5623, described in US-A 2007-028322 or WO 2005/061720); event MIR 162 (cone, insect control, deposited as PTA-8166, US-A 2009-300784 Or event MIR604 (cone, insect control, not deposited, described in US-A2008-167456 or WO2005 / 103301); event MON15985 (cotton, insect control, or Event MON810 (cone, insect control, not deposited, U, deposited as ATCC PTA-2516, described in US-A 2004-250317 or WO 02/100163) Event MON863 (cone, insect control, deposited as ATCC PTA-2605, described in WO2004 / 011601 or US-A2006-095986); event MON87427 (Described as corn, pollination control, ATCC PTA-7899, described in WO2011 / 062904); Event MON87460 (Deposited as corn, stress tolerance, ATCC PTA-8910, WO2009 / 111263 or US Event MON87701 (deposited as soybean, insect control, ATCC PTA-8194, US-A 2009-130071 or Event MON87705 (soybean, quality trait-herbicide tolerance, deposited as ATCC PTA-9241, described in US-A2010-0080887 or WO2010 / 037016); Event MON87708 (soy, herbicide resistance, deposited as ATCC PTA 9670, described in WO2011 / 034704); event MON87754 (soy, quality trait, deposited as ATCC PTA-9385, in WO2010 / 024976 Event MON87769 (deposited as soybean, quality trait, ATCC PTA-8911, US-A2011-0067141 or WO2009 / 10287) Event MON88017 (cone, insect control-herbicide tolerance, deposited as ATCC PTA-5582, described in US-A2008-028482 or WO2005 / 059103); event MON88913 (Wood, Herbicide Tolerance, Deposited as ATCC PTA-4854, described in WO 2004/072235 or US-A 2006-059590); Event MON89034 (Corn, Insect Control, ATCC PTA-7455 deposited Event MON89788 (soybean, herbicide tolerance, deposited as ATCC PTA-6708, US-A200), as described in WO2007 / 140256 or US-A2008-260932 Event MS11 (as rape, pollination control-herbicide tolerance, deposited as ATCC PTA-850 or PTA-2485, described in WO 01/031042). ); Event MS8 (rape, pollination control-herbicide resistance, deposited in ATCC PTA-730, described in WO01 / 041558 or US-A2003-188347); event NK603 (corn, herbicide resistance, Event PE-7 (described in US-A 2007-292854, deposited as ATCC PTA-2478); Event PE-7 (rice, insect control, not deposited, described in WO 2008/114282); Event RF3 (rape Pollination control-herbicide tolerance, deposited as ATCC PTA-730, described in WO 01/041558 or US-A 2003-188347; event RT73 (rape, herbicide tolerance, not deposited, WO 02 / Event T227-1 (sugar beet, herbicide tolerance, not deposited, described in WO 02/44407 or US-A 2009-265817); event T25 (Corn, herbicide resistance, not deposited, described in US-A 2001-029014 or WO 01/051654); event T304-40 (cotton, insect control-herbicide resistance, deposited as ATCC PTA-8171 US-A Event T342-142 (cotton, insect control, not deposited, described in WO2006 / 128568); event TC1507 (corn, insect control-weeding) Drug resistance, not deposited, described in US-A 2005-039226 or WO 2004/099447); event VIP1034 (corn, insect control-herbicide resistance, deposited as ATCC PTA-3925, WO 03/052073 Event 32316 (cone, insect control-herbicide resistance, deposited as PTA-11507, described in WO2011 / 084632), event 4114 (corn, insect control-herbicide) Resistance , Deposited as PTA-11506, described in WO2011 / 084621).

  Very particularly useful transgenic plants that can be treated according to the present invention are plants containing transformation events or combinations of transformation events, such as listed in databases for various national or regional regulatory authorities. These include Event BPS-CV127-9 (soybean, herbicide tolerance, deposited in NCIMB No. 41603, described in WO2010 / 080829); Event DAS68416 (soybean, herbicide tolerance, ATCC Event DP-356043-5 (soy, herbicide resistance, deposited as ATCC PTA-8287, US-A201, deposited as PTA-10442, described in WO2011 / 066384 or WO2011 / 066360) Event EE-1 (Brinjal, insect control, not deposited, described in WO2007 / 091277); Event FI117 (corn, herbicide resistance, ATCC) Event GA21 (cone, herbicide resistance, deposited as ATCC 209033, US-A 2005-086719 or WO 98/044140, deposited as 209031; described in US-A 2006-059581 or WO 98/044140). Event LL27 (described as soybean, herbicide tolerance, NCIMB 41658, described in WO 2006/108674 or US-A 2008-320616) Event LL55 (soybean, herbicide tolerance, deposited as NCIMB 41660, described in WO 2006/108675 or US-A 2008-196127); event MON87701 (soybean, insect control, deposited as ATCC PTA-8194 Event MON87705 (soybean, quality trait-herbicide resistance, deposited as ATCC PTA-9241, US-A2010-00808887 or WO2010 / 037016). Event MON87708 (soybean, herbicide tolerance, deposited as ATCC PTA 9670, described in WO2011 / 034704) ); Event MON87754 (deposited as soybean, quality trait, ATCC PTA-9385, described in WO2010 / 024976); Event MON87769 (deposited as soybean, quality trait, ATCC PTA-8911, US) -Described in A2011-0067141 or WO2009 / 102873); event MON89788 (soybean, herbicide tolerance, deposited as ATCC PTA-6708, described in US-A2006-282915 or WO2006 / 130436) ).

  Particularly preferred is transgenic soybean.

Application rate and timing When the combination or composition of the invention is used as a fungicide, the application rate can be varied within a relatively wide range, depending on the type of application. The application rate of the combination or composition of the invention is:
In the case of treatment of plant parts, for example leaves: 0.1 to 10,000 g / ha, preferably 10 to 1000 g / ha, more preferably 10 to 800 g / ha, even more preferably 50 to 300 g / ha (irrigation or instillation) The application rate can still be reduced, especially when an inert substrate such as rock wool or pearlite is used).
For seed treatment: 2 to 200 g per 100 kg seed, preferably 3 to 150 g per 100 kg seed, more preferably 2.5 to 25 g per 100 kg seed, even more preferably 2.5 to 12 per 100 kg seed .5g;
In the case of soil treatment: 0.1 to 10,000 g / ha, preferably 1 to 5000 g / ha
It is.

  These application rates are merely exemplary and do not limit the purpose of the present invention.

  The combination or composition of the invention can therefore be used to protect plants from attack by the mentioned pathogens for a certain period of time after treatment. The period of time during which protection is provided is generally from 1 to 84 days, preferably from 1 to 56 days, more preferably from 1 to 28 days, most preferably from 1 to 14 days after treatment of the plant with the combination or composition, or from the seed. Up to 200 days after treatment.

  The treatment method according to the invention also provides for simultaneous, separate or sequential use or application of the combination partners (A) and (B). If single active ingredients are applied continuously, i.e. at different times, they are applied in sequence within a reasonably short period of time, e.g. hours or days. Preferably, the order in which compounds (A) and (B) are applied is not essential for the functioning of the present invention.

  According to a preferred embodiment of the invention, the combination partners (A) and (B) are applied simultaneously or sequentially.

  The listed plants can be treated particularly advantageously according to the invention using the combinations or compositions of the invention. The preferred ranges described above for the combination or composition also apply to the treatment of these plants. Of particular emphasis is the treatment of plants with the combinations or compositions specifically mentioned in the text.

  According to another aspect of the present invention, in the combination or composition according to the present invention, the ratio A / B of the compounds can be advantageously chosen to produce a synergistic effect. The term synergistic effect is understood to mean, inter alia, what is defined by Welby in the title “Calculation of the synthetic and antagonistic responses of herbicide combinations”, Weeds, (1967), 15, pages 20-22. Is done.

The latter paper has the formula:

Where E represents the expected percentage of pest inhibition for a combination of two compounds at a defined dose (eg, equal to x and y, respectively), and X is defined Is the percentage of inhibition observed against the pest by compound (A) at the dose (equal to x), Y is observed against the pest by compound (B) at the defined dose (equal to y) The percentage of inhibition made. If the percentage of inhibition observed for the combination is greater than E, there is a synergistic effect.

  The term “synergistic effect” is also defined by the method of Tammes, as defined by “Isoleles, a graphical representation of synergism in pestices”, The Netherlands Journal of Plant Pathology, 70 (1964), page 73-80. .

  The synergistic effect of the fungicide is always present when the fungicidal action of the active compound combination exceeds the expected activity of the active compound.

The expected fungicidal action for a given combination of 2 or 3 active compounds is as follows: R. It can be calculated according to Colby ("Calculating Synthetic and Antagonistic Responses of Herbide Combinations", Weeds 1967 , 15 , 20-22):
X is the efficacy when active compound A was used at an application rate of m g / ha,
Y is the efficacy when active compound B was used at an application rate of n g / ha,
If E is the efficacy when active compounds A and B were used at an application rate of m and n g / ha,
E = X + Y- (X * Y) / 100
It is.

  Here, efficacy is determined in%. 0% means efficacy corresponding to that of the control, 100% efficacy means no infection is observed.

If the actual fungicidal action exceeds the calculated value, the combined action is super-additive, ie there is a synergistic effect. In this case, the actually observed efficacy necessarily exceeds the value calculated using the above formula for expected efficacy (E).

  The invention is illustrated by the following examples. However, the present invention is not limited to these examples.

Example 1 Puccinia triticina-test (wheat) / prophylactic Solvent: 49 parts by weight N, N-dimethylacetamide emulsifier: 1 part by weight alkylaryl polyglycol ether Suitable formulation of the active compound To produce the agent, 1 part by weight of active compound or active compound combination is mixed with a defined amount of solvent and emulsifier and the concentrate is diluted with water to the desired concentration.

  To test for prophylactic activity, seedlings are sprayed with a formulation of active compound or active compound combination at a defined application rate.

  After the spray coating has dried, the plants are sprayed with a spore suspension of P. aeruginosa. The plants are left in the incubation cabinet for 48 hours at about 20 ° C. and about 100% atmospheric relative humidity.

  Plants are placed in a greenhouse at a temperature of about 20 ° C. and an atmospheric relative humidity of about 80%.

  The test is evaluated 8 days after inoculation. 0% means potency corresponding to that of the untreated control, 100% potency means no disease is observed.

  The table below clearly shows that the observed activity of the active compound combinations according to the invention is higher than the calculated activity, ie there is a synergistic effect.

Table 1: Pussinia Triticina test (wheat) / preventive

Example 2 Leptosphaeria nodrum test (wheat) / prophylactic Solvent: 49 parts by weight N, N-dimethylacetamide emulsifier: 1 part by weight alkylaryl polyglycol ether Suitable formulation of the active compound To produce the agent, 1 part by weight of the active compound or active compound combination is mixed with a defined amount of solvent and emulsifier and the concentrate is diluted with water to the desired concentration.

  To test for prophylactic activity, seedlings are sprayed with a formulation of active compound or active compound combination at a defined application rate.

  After the spray coating has dried, the plants are sprayed with a spore suspension of Leptoferia nodrum. The plants are left in the incubation cabinet for 48 hours at about 20 ° C. and about 100% atmospheric relative humidity.

  The plants are placed in a greenhouse at a temperature of about 22 ° C. and an atmospheric relative humidity of about 80%.

  The test is evaluated 8 days after inoculation. 0% means potency corresponding to that of the untreated control, 100% potency means no disease is observed.

  The table below clearly shows that the observed activity of the active compound combinations according to the invention is higher than the calculated activity, ie there is a synergistic effect.

Table 2. Leptosferia nodrum test (wheat) / preventive

Example 3 Septoria tritici-test (wheat) / prophylactic Solvent: 49 parts by weight N, N-dimethylacetamide emulsifier: 1 part by weight alkylaryl polyglycol ether Suitable formulation of active compound To produce the agent, 1 part by weight of active compound or active compound combination is mixed with a defined amount of solvent and emulsifier and the concentrate is diluted with water to the desired concentration.

  To test for prophylactic activity, seedlings are sprayed with a formulation of active compound or active compound combination at a defined application rate.

  After the spray coating has dried, the plants are sprayed with a spore suspension of Septoria tritici. Plants are left in an incubation cabinet for 48 hours at about 20 ° C. and about 100% atmospheric relative humidity, followed by about 15 ° C. in a translucent incubation cabinet for about 60 hours at about 100% atmospheric relative humidity. .

  The plants are placed in a greenhouse at a temperature of about 15 ° C. and an atmospheric relative humidity of about 80%.

  The test is evaluated 21 days after inoculation. 0% means potency corresponding to that of the untreated control, 100% potency means no disease is observed.

  The table below clearly shows that the observed activity of the active compound combinations according to the invention is higher than the calculated activity, ie there is a synergistic effect.

Table 3: Septoria Tritici test (wheat) / preventive

Example 4 Blumeria test (barley) / prophylactic solvent: 49 parts by weight N, N-dimethylacetamide emulsifier: 1 part by weight alkylaryl polyglycol ether 1 part by weight to produce a suitable formulation of the active compound Part of the active compound or active compound combination is mixed with a defined amount of solvent and emulsifier and the concentrate is diluted with water to the desired concentration.

  To test for prophylactic activity, seedlings are sprayed with a formulation of active compound or active compound combination at a defined application rate.

  After the spray coating has dried, the plants are sprinkled with spores of Blumeria graminis f. Sp.

  Plants are placed in a greenhouse at a temperature of about 18 ° C. and an atmospheric relative humidity of about 80% to promote the development of powdery mildew paste.

  The test is evaluated 7 days after inoculation. 0% means potency corresponding to that of the untreated control, 100% potency means no disease is observed.

  The table below clearly shows that the observed activity of the active compound combinations according to the invention is higher than the calculated activity, ie there is a synergistic effect.

Table 4: Blumeria study (barley) / preventive

Claims (14)

A group of host defense inducers selected from (A) isotianil and (B) at least one additional compound selected from the group consisting of: (B1) thiazinyl (2.1) and probenazole (2.2) Members of
A composition comprising a. The composition of claim 1 comprising components (A) :( B) in a weight ratio of 1:25 to 25: 1. A method of preparing a composition comprising mixing the composition of claim 1 or 2 with a bulking agent, a surfactant, or a combination thereof. A method for controlling phytopathogenic microorganisms including fungi and bacteria, wherein the microorganisms or their habitats are contacted with the composition according to claim 1 or 2 , or the component (A) isotianil And contacting with a combination of at least one compound selected from the components (B) thiazinyl (2.1) and probenazole (2.2) .   Phytopathogenic bacteria are Acidoborax avenae and / or Burkholderia glumae in rice, Candida Liberia sp. And Candidatus Libidobacter sp. Xanthomonas axonopodis pv.citri), Pseudomonas syringae pathogenic actinidae in Kiwi (Pseudomonas syringae pv.actinidae), Xanthomonas campestris or Xanthomonas campestris Pathogenic type Pruni (Xanthomonas campestris pv. Pruni), Pseudomonas syringae pathogenic glycinea (Pseudomonas syringae pv. Glycinea) and / or Xanthomonas axonopodis genus p. (Burkholderia spec.) And / or Xanthomonas translucens, Pseudomonas syringae in tomato, Pseudomonas syringae tomato (Pseudomonas sucrose) ae pv. ), Erwinia caratovora and / or Streptomyces scabies. 6. A method according to claim 4 or 5, comprising applying components (A) and (B) simultaneously or sequentially.   The method according to any one of claims 4 to 6, wherein the amount of the composition of claim 1 or 2 is 0.1 g / ha to 10 kg / ha in the case of foliar and soil treatment. A method of processing seeds, the seeds contacting a composition according to claim 1 or 2, or a structure is the component (A) Isotianil and component (B) tiadinil (2.1 And a combination of at least one compound selected from probenazole (2.2) . The method according to claim 8, wherein the seed is a transgenic seed. 10. The method according to claim 8 or 9 , wherein the amount of the composition of claim 1 or 2 is 2 to 200 g / 100 kg seed. The method according to any of claims 8 to 10, wherein the seed is treated with component (A) at the same time as it is treated with component ( B). 10. The method according to claim 8 or 9, wherein the seed is treated with component (A) at a different time than treated with component ( B). Treated with the composition according to claim 1 or 2 were, seeds.   The seed according to claim 13, wherein the seed is a transgenic seed.