JP6235603B2 - 消炎性および/または免疫抑制性活性成分としてのデルフィニジン複合体 - Google Patents
消炎性および/または免疫抑制性活性成分としてのデルフィニジン複合体 Download PDFInfo
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- JP6235603B2 JP6235603B2 JP2015542208A JP2015542208A JP6235603B2 JP 6235603 B2 JP6235603 B2 JP 6235603B2 JP 2015542208 A JP2015542208 A JP 2015542208A JP 2015542208 A JP2015542208 A JP 2015542208A JP 6235603 B2 JP6235603 B2 JP 6235603B2
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- delphinidin
- inflammatory
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- cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
- A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
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- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
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- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Inorganic Chemistry (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Communicable Diseases (AREA)
- Physical Education & Sports Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Vascular Medicine (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12192717 | 2012-11-15 | ||
| EP12192717.2 | 2012-11-15 | ||
| PCT/EP2013/072856 WO2014075935A1 (de) | 2012-11-15 | 2013-11-01 | Delphinidinkomplex als antiphlogistischer oder immunsuppressiver wirkstoff |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503416A JP2016503416A (ja) | 2016-02-04 |
| JP2016503416A5 JP2016503416A5 (https=) | 2016-11-10 |
| JP6235603B2 true JP6235603B2 (ja) | 2017-11-22 |
Family
ID=47189771
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015542208A Active JP6235603B2 (ja) | 2012-11-15 | 2013-11-01 | 消炎性および/または免疫抑制性活性成分としてのデルフィニジン複合体 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9925274B2 (https=) |
| EP (1) | EP2919791B1 (https=) |
| JP (1) | JP6235603B2 (https=) |
| KR (1) | KR102147084B1 (https=) |
| CN (1) | CN104870001B (https=) |
| CA (1) | CA2890022C (https=) |
| DK (1) | DK2919791T3 (https=) |
| WO (1) | WO2014075935A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014075935A1 (de) | 2012-11-15 | 2014-05-22 | Sapiotec Gmbh | Delphinidinkomplex als antiphlogistischer oder immunsuppressiver wirkstoff |
| US9949947B2 (en) | 2012-12-11 | 2018-04-24 | Sapiotec Gmbh | Delphinidin for combating melanoma cells |
| CN106361755A (zh) * | 2016-10-23 | 2017-02-01 | 徐州诺克非医药科技有限公司 | 含Zoarenone用于治疗溃疡性结肠炎的药物 |
| WO2022050431A1 (ko) * | 2020-09-01 | 2022-03-10 | 경상국립대학교병원 | 골관절염 예방 또는 치료용 약학 조성물 및 건강기능식품 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5946228A (ja) | 1982-09-08 | 1984-03-15 | Zeria Shinyaku Kogyo Kk | 生物学的に活性な有機化合物の水溶性及びリンパ移行性薬剤の製造方法 |
| HU199444B (en) | 1985-09-10 | 1990-02-28 | Chinoin Gyogyszer Es Vegyeszet | Process for producing 7-isopropoxy-isoflavone-cyclodextrene inclusion complex and pharmaceutical compositions therefrom |
| GB8907008D0 (en) | 1989-03-28 | 1989-05-10 | Inverni Della Beffa Spa | Intermediates useful for the synthesis for delphinidin chloride |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| US5376645A (en) * | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| ZA962214B (en) | 1995-04-10 | 1996-10-07 | Farmarc Nederland Bv | Pharmaceutical composition |
| GB2307176A (en) | 1995-11-15 | 1997-05-21 | Todd Selwyn Everest | Anti-inflammatory clathrating agents for topical use |
| HUP9701945A3 (en) | 1997-11-10 | 2000-04-28 | Hexal Ag | Pharmaceutical composition for injection containing cyclodextrin and taxoids |
| JP4101346B2 (ja) | 1998-02-18 | 2008-06-18 | ダイセル化学工業株式会社 | 酸化触媒系及びそれを用いた酸化方法 |
| CA2320772A1 (en) | 1998-02-23 | 1999-08-26 | Cyclops, Ehf. | High-energy cyclodextrin complexes |
| US6699849B1 (en) | 1998-02-23 | 2004-03-02 | Cyclops, Ehf. | Cyclodextrin complexes of benzodiazepines |
| GB2350297A (en) | 1999-05-27 | 2000-11-29 | Abbott Lab | Injectable halogenated anesthetic formulation in emulsion form |
| AU6527300A (en) | 1999-08-11 | 2001-03-05 | Josef Pitha | Potentiation of inclusion complex formation of cyclodextrin derivatives |
| AU7937500A (en) | 1999-10-27 | 2001-05-08 | Farmarc Nederland Bv | Pharmaceutical composition containing midazolam |
| ES2250460T3 (es) | 2000-09-12 | 2006-04-16 | Meiji Seika Kaisha, Ltd. | Procedimiento para la preparacion de glucosido de antocianidina purificado. |
| JP4334229B2 (ja) | 2001-03-20 | 2009-09-30 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | プロポフォール及びスルホアルキルエーテルシクロデキストリン含有製剤 |
| US7034013B2 (en) | 2001-03-20 | 2006-04-25 | Cydex, Inc. | Formulations containing propofol and a sulfoalkyl ether cyclodextrin |
| JP2003171274A (ja) | 2001-12-07 | 2003-06-17 | Tomihiko Higuchi | 薬剤耐性菌感染症治療のための医薬組成物および消毒剤 |
| BR0307518A (pt) | 2002-02-01 | 2004-12-28 | Shimoda Biotech Pty Ltd | Composição farmacêutica |
| US6869939B2 (en) * | 2002-05-04 | 2005-03-22 | Cydex, Inc. | Formulations containing amiodarone and sulfoalkyl ether cyclodextrin |
| JP2004238336A (ja) * | 2003-02-07 | 2004-08-26 | Sanei Gen Ffi Inc | 水易溶性包接フラボノイド類の製造方法 |
| US20050013880A1 (en) | 2003-03-06 | 2005-01-20 | Magnuson Bernadene Ann | Anthocyanin-rich compositions and methods for inhibiting cancer cell growth |
| HRP20050924A2 (en) | 2003-03-28 | 2006-08-31 | Ivax Corporation | Cladribine formulations for improved oral and transmucosal delivery |
| JPWO2005067905A1 (ja) | 2004-01-14 | 2007-12-27 | 株式会社大塚製薬工場 | プロポフォール含有脂肪乳剤 |
| CN1317961C (zh) | 2004-03-25 | 2007-05-30 | 吴朝琴 | 冻干草莓加工工艺 |
| WO2006076387A2 (en) | 2005-01-11 | 2006-07-20 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Cyanidin-3-glucoside as an anti-neoplastic agent |
| DE102005017775A1 (de) | 2005-04-13 | 2006-10-19 | Schering Ag | Komplexe aus Vitamin D-Verbindungen oder deren Analoga mit einem 5Z,7E,10(19)-Trien-System und methlierten Derivaten des ß-Cyclodextrins |
| KR100733913B1 (ko) * | 2005-08-30 | 2007-07-02 | 한국화학연구원 | 안토시아닌을 포함하는 뇌세포 보호제와 뇌경색 및 뇌졸중예방 또는 치료제 |
| US7645748B2 (en) | 2006-04-03 | 2010-01-12 | Forbes Medi-Tech Inc. | Sterol/stanol phosphorylnitroderivatives and use thereof |
| WO2008070490A2 (en) | 2006-11-28 | 2008-06-12 | Wisconsin Alumni Research Foundation | Fluoropolymer-based emulsions for the intravenous delivery of fluorinated volatile anesthetics |
| KR100756656B1 (ko) * | 2006-12-12 | 2007-09-10 | 한국화학연구원 | 안토시아닌을 포함하는 뇌경색 또는 뇌졸중 예방 및 개선용건강식품 |
| KR100880876B1 (ko) * | 2007-04-11 | 2009-01-30 | 경상대학교산학협력단 | 검정콩 껍질로부터 추출한 안토시아닌을 함유하는 피판이나조직의 허혈-재관류 손상의 예방 또는 치료용 의약 조성물 |
| WO2009018326A2 (en) * | 2007-07-31 | 2009-02-05 | Limerick Biopharma, Inc. | Soluble pyrone analogs methods and compositions |
| JP5574600B2 (ja) * | 2007-12-17 | 2014-08-20 | 日本製薬工業株式会社 | 吸収性骨疾患の予防・治療剤 |
| EP2106786A1 (de) | 2008-04-04 | 2009-10-07 | Roewer, Norbert, Univ.-Prof. Dr. med. | Pharmazeutische Zubereitung mit permethyliertem Cyclodextrin |
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| US20120083460A1 (en) | 2009-03-25 | 2012-04-05 | San Ei Gen F.F.I., Inc. | Readily water-soluble isoquercitrin composition |
| EP2437770A4 (en) | 2009-06-05 | 2013-11-06 | Univ Colorado Regents | ANTIMICROBIAL PEPTIDES |
| EP2344154B1 (en) | 2009-10-21 | 2016-12-07 | Maqui New Life S.A. | Compositions that include anthocyanidins and methods of use |
| EP2345427A1 (de) | 2010-01-14 | 2011-07-20 | SapioTec GmbH | Flurankomplex |
| CN102892310B (zh) | 2010-03-13 | 2016-07-06 | 伊斯顿庞德实验室有限公司 | 结合脂肪的组合物 |
| DE102010042615A1 (de) | 2010-10-19 | 2012-04-19 | Wacker Chemie Ag | 1:1, 2:1- oder 3:1-Komplex bestehend aus einem Cyclodextrin oder Cyclodextrinderivat und einem halogeniertem Ether, seine Herstellung und seine Verwendung als Schlafmittel |
| AU2010366535A1 (en) | 2010-12-31 | 2013-07-11 | Eastpond Laboratories Limited | Cellular hydration compositions containing cyclodextrins |
| DK2484350T3 (en) | 2011-02-04 | 2016-08-01 | Norbert Univ -Prof Dr Med Roewer | A pharmaceutical composition containing a complex of a cyclodextrin with a propofolsalt |
| JP6193970B2 (ja) | 2012-03-30 | 2017-09-06 | ザピオテック・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングSAPIOTEC GmbH | 黄色ブドウ球菌(Staphylococcusaureus)に対するデルフィニジンの使用 |
| CA2869056C (en) | 2012-03-30 | 2020-02-25 | Sapiotec Gmbh | Anthocyanidin complex |
| CN104780925A (zh) * | 2012-10-17 | 2015-07-15 | 赛博尔泰克股份公司 | 用于治疗多发性骨髓瘤的花青素络合物 |
| WO2014075935A1 (de) | 2012-11-15 | 2014-05-22 | Sapiotec Gmbh | Delphinidinkomplex als antiphlogistischer oder immunsuppressiver wirkstoff |
| US9949947B2 (en) | 2012-12-11 | 2018-04-24 | Sapiotec Gmbh | Delphinidin for combating melanoma cells |
| EP2913050A1 (de) | 2014-02-28 | 2015-09-02 | SapioTec GmbH | Verfahren zur Herstellung eines Flurankomplexes |
| EP2913366A1 (de) | 2014-02-28 | 2015-09-02 | SapioTec GmbH | Anthocyanidin-Komplex |
-
2013
- 2013-11-01 WO PCT/EP2013/072856 patent/WO2014075935A1/de not_active Ceased
- 2013-11-01 DK DK13786226.4T patent/DK2919791T3/da active
- 2013-11-01 EP EP13786226.4A patent/EP2919791B1/de active Active
- 2013-11-01 CA CA2890022A patent/CA2890022C/en active Active
- 2013-11-01 CN CN201380058822.9A patent/CN104870001B/zh active Active
- 2013-11-01 US US14/443,166 patent/US9925274B2/en active Active
- 2013-11-01 JP JP2015542208A patent/JP6235603B2/ja active Active
- 2013-11-01 KR KR1020157014744A patent/KR102147084B1/ko active Active
Also Published As
| Publication number | Publication date |
|---|---|
| KR102147084B1 (ko) | 2020-08-24 |
| CN104870001B (zh) | 2019-01-18 |
| CA2890022C (en) | 2020-07-14 |
| US9925274B2 (en) | 2018-03-27 |
| WO2014075935A1 (de) | 2014-05-22 |
| EP2919791B1 (de) | 2017-03-22 |
| CA2890022A1 (en) | 2014-05-22 |
| KR20150084030A (ko) | 2015-07-21 |
| EP2919791A1 (de) | 2015-09-23 |
| DK2919791T3 (da) | 2017-07-17 |
| CN104870001A (zh) | 2015-08-26 |
| JP2016503416A (ja) | 2016-02-04 |
| US20150306247A1 (en) | 2015-10-29 |
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