JP6147737B2 - 選択的グリコシダーゼ阻害剤およびその使用 - Google Patents

選択的グリコシダーゼ阻害剤およびその使用 Download PDF

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JP6147737B2
JP6147737B2 JP2014517357A JP2014517357A JP6147737B2 JP 6147737 B2 JP6147737 B2 JP 6147737B2 JP 2014517357 A JP2014517357 A JP 2014517357A JP 2014517357 A JP2014517357 A JP 2014517357A JP 6147737 B2 JP6147737 B2 JP 6147737B2
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fluoro
pyrano
tetrahydro
thiazol
hydroxyethyl
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JP2014524911A (ja
JP2014524911A5 (cg-RX-API-DMAC7.html
Inventor
トン−シュアン リ，
トン−シュアン リ，
アーネスト ジェイ． マケーチャン，
アーネスト ジェイ． マケーチャン，
デイビッド ジェイ． ヴォカドゥロ，
デイビッド ジェイ． ヴォカドゥロ，
ユアンシ ジョウ，
ユアンシ ジョウ，
ヨンバオ ジュー，
ヨンバオ ジュー，
ハロルド ジー． セルニック，
ハロルド ジー． セルニック，
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Merck Sharp and Dohme LLC
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Merck Sharp and Dohme LLC
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    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/06—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing nitrogen as ring hetero atoms
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
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    • G01N2333/914—Hydrolases (3)
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    • G—PHYSICS
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Physical Education & Sports Medicine (AREA)
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  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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JP2014517357A 2011-06-27 2012-06-27 選択的グリコシダーゼ阻害剤およびその使用 Active JP6147737B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161501377P 2011-06-27 2011-06-27
US61/501,377 2011-06-27
PCT/CA2012/050433 WO2013000084A1 (en) 2011-06-27 2012-06-27 Selective glycosidase inhibitors and uses thereof

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JP2014524911A JP2014524911A (ja) 2014-09-25
JP2014524911A5 JP2014524911A5 (cg-RX-API-DMAC7.html) 2015-08-13
JP6147737B2 true JP6147737B2 (ja) 2017-06-14

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EP (1) EP2723753B1 (cg-RX-API-DMAC7.html)
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KR (1) KR102054744B1 (cg-RX-API-DMAC7.html)
CN (1) CN103889996B (cg-RX-API-DMAC7.html)
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AU2009276223B2 (en) 2008-08-01 2015-04-02 Simon Fraser University Selective glycosidase inhibitors and uses thereof
EP2569291B1 (en) 2010-05-11 2016-04-06 Simon Fraser University Selective glycosidase inhibitors and uses thereof
EP2638052B1 (en) 2010-11-08 2017-03-22 Alectos Therapeutics, Inc. Selective glycosidase inhibitors and uses thereof
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WO2012126091A1 (en) 2011-03-24 2012-09-27 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
WO2012129651A1 (en) 2011-03-31 2012-10-04 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
WO2013000084A1 (en) 2011-06-27 2013-01-03 Alectos Therapeutics Inc. Selective glycosidase inhibitors and uses thereof
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JP2015534991A (ja) 2012-10-31 2015-12-07 アレクトス・セラピューティクス・インコーポレイテッド グリコシダーゼ阻害剤およびその使用
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US9409924B2 (en) 2016-08-09
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