JP6145946B2 - 併用als療法 - Google Patents

併用als療法 Download PDF

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Publication number
JP6145946B2
JP6145946B2 JP2014520335A JP2014520335A JP6145946B2 JP 6145946 B2 JP6145946 B2 JP 6145946B2 JP 2014520335 A JP2014520335 A JP 2014520335A JP 2014520335 A JP2014520335 A JP 2014520335A JP 6145946 B2 JP6145946 B2 JP 6145946B2
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JP
Japan
Prior art keywords
riluzole
composition
administered
combination
subject
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Expired - Fee Related
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JP2014520335A
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English (en)
Japanese (ja)
Other versions
JP2014520856A (ja
JP2014520856A5 (enExample
Inventor
ジェシー シダーバーム,
ジェシー シダーバーム,
マオ, ジョン
ジョン マオ,
ファディー マリック,
ファディー マリック,
アンドリュー エー. ウォルフ,
アンドリュー エー. ウォルフ,
Original Assignee
サイトキネティックス, インコーポレイテッド
サイトキネティックス, インコーポレイテッド
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Publication of JP2014520856A publication Critical patent/JP2014520856A/ja
Publication of JP2014520856A5 publication Critical patent/JP2014520856A5/ja
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/428Thiazoles condensed with carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014520335A 2011-07-13 2012-07-12 併用als療法 Expired - Fee Related JP6145946B2 (ja)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201161507381P 2011-07-13 2011-07-13
US61/507,381 2011-07-13
US201161544533P 2011-10-07 2011-10-07
US61/544,533 2011-10-07
US201261637770P 2012-04-24 2012-04-24
US201261637759P 2012-04-24 2012-04-24
US61/637,759 2012-04-24
US61/637,770 2012-04-24
US201261646699P 2012-05-14 2012-05-14
US61/646,699 2012-05-14
PCT/US2012/046523 WO2013010015A2 (en) 2011-07-13 2012-07-12 Combination als therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017090313A Division JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Publications (3)

Publication Number Publication Date
JP2014520856A JP2014520856A (ja) 2014-08-25
JP2014520856A5 JP2014520856A5 (enExample) 2015-09-03
JP6145946B2 true JP6145946B2 (ja) 2017-06-14

Family

ID=47506929

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014520335A Expired - Fee Related JP6145946B2 (ja) 2011-07-13 2012-07-12 併用als療法
JP2017090313A Pending JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017090313A Pending JP2017128610A (ja) 2011-07-13 2017-04-28 併用als療法

Country Status (16)

Country Link
US (1) US10272082B2 (enExample)
EP (1) EP2731611B1 (enExample)
JP (2) JP6145946B2 (enExample)
KR (1) KR101951220B1 (enExample)
CN (2) CN104039148A (enExample)
AU (2) AU2012281042B2 (enExample)
BR (1) BR112014000742A2 (enExample)
CA (1) CA2849213A1 (enExample)
EA (2) EA028060B1 (enExample)
HK (1) HK1197178A1 (enExample)
IL (1) IL230391B (enExample)
IN (1) IN2014DN00200A (enExample)
PH (1) PH12014500094A1 (enExample)
SG (1) SG10201605707UA (enExample)
WO (1) WO2013010015A2 (enExample)
ZA (1) ZA201400236B (enExample)

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US20160263110A1 (en) * 2013-11-04 2016-09-15 Ab Science Use of masitinib for treatment of amyotrophic lateral sclerosis
EP3137622B1 (en) * 2014-04-29 2021-11-24 Cytokinetics, Inc. Methods of reducing decline in vital capacity
EA201791110A1 (ru) * 2014-11-21 2017-11-30 Биохэвен Фармасьютикэл Холдинг Компани Лтд. Сублингвальное введение рилузола
LT3220891T (lt) 2014-11-21 2019-11-11 Biohaven Therapeutics Ltd Poliežuvinė riluzolio kompozicija
EP3072513A1 (en) * 2015-03-26 2016-09-28 Medday Biotin for treating Amyotrophic lateral sclerosis
SG11201808106YA (en) 2016-03-25 2018-10-30 Ab Science Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
EP4031135A4 (en) 2019-09-20 2023-10-18 Icahn School of Medicine at Mount Sinai CONTROLLED RELEASE FORMULATIONS OF RILUZOLE AND USES THEREOF

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Also Published As

Publication number Publication date
CN109316480A (zh) 2019-02-12
EP2731611A4 (en) 2015-02-18
JP2017128610A (ja) 2017-07-27
CA2849213A1 (en) 2013-01-17
KR101951220B1 (ko) 2019-02-22
JP2014520856A (ja) 2014-08-25
AU2012281042A1 (en) 2014-01-30
PH12014500094A1 (en) 2014-03-17
SG10201605707UA (en) 2016-09-29
IL230391B (en) 2019-03-31
KR20140074270A (ko) 2014-06-17
AU2012281042B2 (en) 2016-07-14
US20140243344A1 (en) 2014-08-28
WO2013010015A2 (en) 2013-01-17
NZ619924A (en) 2016-02-26
EA028060B1 (ru) 2017-10-31
WO2013010015A3 (en) 2014-05-15
BR112014000742A2 (pt) 2016-08-23
CN104039148A (zh) 2014-09-10
IN2014DN00200A (enExample) 2015-06-05
EA201490011A1 (ru) 2014-08-29
EA201791043A1 (ru) 2017-09-29
AU2016244263A1 (en) 2016-11-03
HK1197178A1 (en) 2015-01-09
US10272082B2 (en) 2019-04-30
EP2731611B1 (en) 2019-09-18
EP2731611A2 (en) 2014-05-21
ZA201400236B (en) 2014-10-29

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