JP6110140B2 - ナノエマルションワクチン - Google Patents

ナノエマルションワクチン Download PDF

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Publication number
JP6110140B2
JP6110140B2 JP2012516271A JP2012516271A JP6110140B2 JP 6110140 B2 JP6110140 B2 JP 6110140B2 JP 2012516271 A JP2012516271 A JP 2012516271A JP 2012516271 A JP2012516271 A JP 2012516271A JP 6110140 B2 JP6110140 B2 JP 6110140B2
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volume
oil
chloride
dih
composition
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Japanese (ja)
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JP2012530146A (ja
JP2012530146A5 (https=
Inventor
ダブリュー. ルカーチ,ニコラス
ダブリュー. ルカーチ,ニコラス
エム. リンデル,デニス
エム. リンデル,デニス
アール. ベイカー,ジュニア.,ジェームズ
アール. ベイカー,ジュニア.,ジェームズ
Original Assignee
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン
ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン
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Publication of JP2012530146A publication Critical patent/JP2012530146A/ja
Publication of JP2012530146A5 publication Critical patent/JP2012530146A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/155Paramyxoviridae, e.g. parainfluenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541Mucosal route
    • A61K2039/543Mucosal route intranasal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0008Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18511Pneumovirus, e.g. human respiratory syncytial virus
    • C12N2760/18534Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012516271A 2009-06-16 2010-06-16 ナノエマルションワクチン Active JP6110140B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18752909P 2009-06-16 2009-06-16
US61/187,529 2009-06-16
PCT/US2010/038854 WO2010148111A1 (en) 2009-06-16 2010-06-16 Nanoemulsion vaccines

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2015209217A Division JP6122083B2 (ja) 2009-06-16 2015-10-23 ナノエマルションワクチン

Publications (3)

Publication Number Publication Date
JP2012530146A JP2012530146A (ja) 2012-11-29
JP2012530146A5 JP2012530146A5 (https=) 2015-03-05
JP6110140B2 true JP6110140B2 (ja) 2017-04-05

Family

ID=43306638

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2012516271A Active JP6110140B2 (ja) 2009-06-16 2010-06-16 ナノエマルションワクチン
JP2015209217A Active JP6122083B2 (ja) 2009-06-16 2015-10-23 ナノエマルションワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2015209217A Active JP6122083B2 (ja) 2009-06-16 2015-10-23 ナノエマルションワクチン

Country Status (8)

Country Link
US (1) US20100316673A1 (https=)
EP (2) EP2442827B1 (https=)
JP (2) JP6110140B2 (https=)
CN (1) CN102596243B (https=)
BR (1) BRPI1014031A2 (https=)
CA (1) CA2765511C (https=)
ES (1) ES2566646T3 (https=)
WO (1) WO2010148111A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492525B2 (en) 2011-07-06 2016-11-15 Nanobio Corporation Human respiratory syncytial virus vaccine
JP6460792B2 (ja) * 2011-09-09 2019-01-30 ナノバイオ コーポレーション ナノエマルション呼吸器合胞体ウイルス(rsv)サブユニットワクチン
EP4112076A1 (en) * 2014-10-10 2023-01-04 The Regents of The University of Michigan Nanoemulsion compositions for preventing, suppressing or eliminating allergic and inflammatory disease
JP2020526567A (ja) * 2017-07-13 2020-08-31 ナノビオ コーポレイションNanobio Corporation クラミジアナノエマルジョンワクチン
MX2020004151A (es) 2017-10-30 2020-08-13 Takeda Pharmaceuticals Co Detergentes compatibles con el medio ambiente para la inactivacion de virus envueltos en lipidos.
WO2022149609A1 (ja) * 2021-01-07 2022-07-14 国立大学法人東京工業大学 Mhc分子に適合する病原微生物由来のペプチドが担持された複合蛋白質単量体、当該単量体の会合体、及び当該会合体を有効成分とするコンポーネントワクチン、並びに、免疫後の生理活性物質の分泌に関する情報の取得方法
EP4319880A4 (en) * 2021-04-08 2025-03-19 Codagenix Inc. Method of eliciting an immune response against respiratory syncytial virus
CN116532057A (zh) * 2023-05-08 2023-08-04 四川大学 一种不依赖金属离子的超分子水凝胶及其制备方法和应用

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Also Published As

Publication number Publication date
EP2442827A4 (en) 2013-04-17
JP2012530146A (ja) 2012-11-29
HK1173661A1 (zh) 2013-05-24
WO2010148111A1 (en) 2010-12-23
JP6122083B2 (ja) 2017-04-26
CA2765511A1 (en) 2010-12-23
ES2566646T3 (es) 2016-04-14
BRPI1014031A2 (pt) 2018-02-20
EP3020412B1 (en) 2017-10-11
CA2765511C (en) 2015-05-12
EP3020412A1 (en) 2016-05-18
EP2442827A1 (en) 2012-04-25
US20100316673A1 (en) 2010-12-16
JP2016026202A (ja) 2016-02-12
CN102596243A (zh) 2012-07-18
EP2442827B1 (en) 2016-01-06
CN102596243B (zh) 2015-10-21

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