JP6091100B2 - 共焦点顕微装置 - Google Patents

共焦点顕微装置 Download PDF

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Publication number
JP6091100B2
JP6091100B2 JP2012154398A JP2012154398A JP6091100B2 JP 6091100 B2 JP6091100 B2 JP 6091100B2 JP 2012154398 A JP2012154398 A JP 2012154398A JP 2012154398 A JP2012154398 A JP 2012154398A JP 6091100 B2 JP6091100 B2 JP 6091100B2
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Japan
Prior art keywords
light
aperture
sample
apertures
confocal microscope
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JP2012154398A
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Japanese (ja)
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JP2014016531A5 (enExample
JP2014016531A (ja
Inventor
見斗 会沢
見斗 会沢
克史 前田
克史 前田
井上 勉
勉 井上
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Jasco Corp
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Jasco Corp
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Priority to JP2012154398A priority Critical patent/JP6091100B2/ja
Priority to EP13175871.6A priority patent/EP2685304A1/en
Publication of JP2014016531A publication Critical patent/JP2014016531A/ja
Publication of JP2014016531A5 publication Critical patent/JP2014016531A5/ja
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    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0032Optical details of illumination, e.g. light-sources, pinholes, beam splitters, slits, fibers
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0036Scanning details, e.g. scanning stages
    • G02B21/004Scanning details, e.g. scanning stages fixed arrays, e.g. switchable aperture arrays
    • GPHYSICS
    • G02OPTICS
    • G02BOPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00Microscopes
    • G02B21/0004Microscopes specially adapted for specific applications
    • G02B21/002Scanning microscopes
    • G02B21/0024Confocal scanning microscopes (CSOMs) or confocal "macroscopes"; Accessories which are not restricted to use with CSOMs, e.g. sample holders
    • G02B21/0052Optical details of the image generation
    • G02B21/0064Optical details of the image generation multi-spectral or wavelength-selective arrangements, e.g. wavelength fan-out, chromatic profiling

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  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
JP2012154398A 2012-07-10 2012-07-10 共焦点顕微装置 Active JP6091100B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2012154398A JP6091100B2 (ja) 2012-07-10 2012-07-10 共焦点顕微装置
EP13175871.6A EP2685304A1 (en) 2012-07-10 2013-07-10 Spectroscopic confocal microscope with aperture stop for increased spatial resolution and parallelized data acquisition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2012154398A JP6091100B2 (ja) 2012-07-10 2012-07-10 共焦点顕微装置

Publications (3)

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JP2014016531A JP2014016531A (ja) 2014-01-30
JP2014016531A5 JP2014016531A5 (enExample) 2015-08-13
JP6091100B2 true JP6091100B2 (ja) 2017-03-08

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Family Applications (1)

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JP2012154398A Active JP6091100B2 (ja) 2012-07-10 2012-07-10 共焦点顕微装置

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EP (1) EP2685304A1 (enExample)
JP (1) JP6091100B2 (enExample)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015166763A (ja) * 2014-03-03 2015-09-24 エバ・ジャパン 株式会社 顕微鏡装置および解析方法
RU2579640C1 (ru) * 2014-10-14 2016-04-10 Владимир Алексеевич Шульгин Конфокальный спектроанализатор изображений
CN104614846B (zh) * 2015-03-03 2017-01-11 北京理工大学 反射式分光瞳差动共焦‑光声显微成像装置与方法
CN104677884B (zh) * 2015-03-17 2017-07-11 北京理工大学 高空间分辨激光分光瞳差动共焦质谱显微成像方法与装置
DE102015209756A1 (de) * 2015-05-28 2016-12-01 Carl Zeiss Microscopy Gmbh Anordnung und Verfahren zur Lichtblattmikroskopie
JP6661307B2 (ja) 2015-08-31 2020-03-11 大塚電子株式会社 顕微分光装置
CN106610528A (zh) * 2016-12-27 2017-05-03 中国科学院长春光学精密机械与物理研究所 长波红外和短波红外复合准直光学系统
US11085753B2 (en) * 2017-02-15 2021-08-10 ContinUse Biometrics Ltd. System and method for use in remote sensing
RU2658140C1 (ru) * 2017-05-24 2018-06-19 федеральное государственное бюджетное образовательное учреждение высшего образования "Воронежский государственный университет" (ФГБОУ ВО "ВГУ") Конфокальный спектроанализатор флуоресцентных изображений
CN107607059B (zh) * 2017-10-10 2023-07-25 东莞市嘉仪自动化设备科技有限公司 一种一键式3d轮廓测量设备及其测量计算方法
CN109085119A (zh) * 2018-09-04 2018-12-25 席鹏 一种拉曼层析光谱检测的共聚焦三维成像系统和实现方法
CN110426124A (zh) * 2019-08-12 2019-11-08 长春理工大学 用于芯片式光谱仪能够实现信号光耦合与对准监测的装置
CN112285090A (zh) * 2020-09-29 2021-01-29 军事科学院系统工程研究院卫勤保障技术研究所 一种便携式共焦单细胞拉曼散射检测系统
GB2599651B (en) 2020-10-06 2024-07-24 Andor Tech Limited Confocal Raman analysing apparatus and method
CN114280774A (zh) * 2021-12-30 2022-04-05 深圳立仪科技有限公司 一种带光谱共焦测量功能的多功能装置
CN116088137A (zh) * 2022-12-30 2023-05-09 天府兴隆湖实验室 光学系统
FR3147862B1 (fr) * 2023-04-14 2025-07-18 Horiba France Sas Spectromètre optique et microscope Raman comprenant un tel spectromètre
CN118329205B (zh) * 2024-04-16 2024-11-26 上海默乐光检科技有限公司 一种角分辨光谱测量方法及系统

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3667397B2 (ja) 1995-09-04 2005-07-06 日本分光株式会社 ラマン分光装置
US5804813A (en) * 1996-06-06 1998-09-08 National Science Council Of Republic Of China Differential confocal microscopy
JP2004191251A (ja) * 2002-12-12 2004-07-08 Olympus Corp 蛍光分光分析装置
JP4137682B2 (ja) * 2003-03-31 2008-08-20 オリンパス株式会社 蛍光分光分析装置
JP4887989B2 (ja) * 2005-12-02 2012-02-29 ナノフォトン株式会社 光学顕微鏡及びスペクトル測定方法
DE102006007170B4 (de) * 2006-02-08 2009-06-10 Sirona Dental Systems Gmbh Verfahren und Anordnung zur schnellen und robusten chromatisch konfokalen 3D-Messtechnik
DE102007019267A1 (de) * 2007-04-24 2008-10-30 Degudent Gmbh Messanordnung sowie Verfahren zum dreidimensionalen Messen eines Objekts
US20080277595A1 (en) * 2007-05-10 2008-11-13 Pacific Biosciences Of California, Inc. Highly multiplexed confocal detection systems and methods of using same
US8773760B2 (en) * 2009-04-27 2014-07-08 The Arizona Board Of Regents On Behalf Of The University Of Arizona Multi-point scan architecture
JP5838466B2 (ja) * 2011-03-11 2016-01-06 ナノフォトン株式会社 光学顕微鏡、及び分光測定方法

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Publication number Publication date
EP2685304A1 (en) 2014-01-15
JP2014016531A (ja) 2014-01-30

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