JP6082396B2 - 誤差補償を伴うバイオセンサ - Google Patents

誤差補償を伴うバイオセンサ Download PDF

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JP6082396B2
JP6082396B2 JP2014531954A JP2014531954A JP6082396B2 JP 6082396 B2 JP6082396 B2 JP 6082396B2 JP 2014531954 A JP2014531954 A JP 2014531954A JP 2014531954 A JP2014531954 A JP 2014531954A JP 6082396 B2 JP6082396 B2 JP 6082396B2
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function
output signal
error
sample
signal processing
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JP2014527186A (ja
JP2014527186A5 (enExample
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ウー，ホワン−ピーン
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Bayer Healthcare LLC
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Bayer Healthcare LLC
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP2014531954A 2011-09-21 2012-09-20 誤差補償を伴うバイオセンサ Active JP6082396B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161537145P 2011-09-21 2011-09-21
US61/537,145 2011-09-21
PCT/US2012/056280 WO2013043839A1 (en) 2011-09-21 2012-09-20 Biosensor with error compensation

Publications (3)

Publication Number Publication Date
JP2014527186A JP2014527186A (ja) 2014-10-09
JP2014527186A5 JP2014527186A5 (enExample) 2015-11-12
JP6082396B2 true JP6082396B2 (ja) 2017-02-15

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Family Applications (1)

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JP2014531954A Active JP6082396B2 (ja) 2011-09-21 2012-09-20 誤差補償を伴うバイオセンサ

Country Status (8)

Country Link
US (2) US9775806B2 (enExample)
EP (3) EP3586831A1 (enExample)
JP (1) JP6082396B2 (enExample)
KR (1) KR20140063829A (enExample)
ES (2) ES2757909T3 (enExample)
MX (1) MX350696B (enExample)
TW (1) TWI600892B (enExample)
WO (1) WO2013043839A1 (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX368104B (es) * 2010-03-22 2019-09-19 Ascensia Diabetes Care Holdings Ag Compensacion residual para un biosensor.
CA2902541A1 (en) * 2013-03-14 2014-10-02 Bayer Healthcare Llc System error compensation of analyte concentration determinations
HK1221771A1 (zh) * 2013-03-14 2017-06-09 安晟信医疗科技控股公司 分析物浓度测定的标准化校准
EP3457141B1 (en) 2013-03-14 2021-09-29 Ascensia Diabetes Care Holdings AG Progressive approximation of sample analyte concentration
US10551362B2 (en) 2013-03-26 2020-02-04 Waters Technologies Corporation Method for extending the dynamic range of absorbance detectors
GB2531728A (en) * 2014-10-27 2016-05-04 Cilag Gmbh Int Method for determining diffusion
HK1248818A1 (zh) 2015-05-15 2018-10-19 安晟信医疗科技控股公司 改进的生物传感器系统分析物测量
CN109690304A (zh) * 2016-07-12 2019-04-26 安晟信医疗科技控股公司 通过使用来自两个电极的交替输出信号进行电化学分析的方法
CA3045090A1 (en) * 2016-12-05 2018-06-14 Ascensia Diabetes Care Holdings Ag Risk factor monitoring
CN113167760B (zh) * 2018-12-02 2023-11-03 聚合物技术系统公司 用于电化学测试条带中的电子门特征的系统和方法
CN113490454A (zh) 2019-02-05 2021-10-08 安晟信医疗科技控股公司 用于探测连续分析物感测及自动更正的传感器操作的设备及方法
CN113646625A (zh) 2019-02-22 2021-11-12 安晟信医疗科技控股公司 用于使用谐波关系监测分析物浓度的方法和设备
CN109884150B (zh) * 2019-03-08 2021-05-14 武汉璟泓科技股份有限公司 一种红细胞积压校正方法及存储介质
US11678820B2 (en) 2019-09-10 2023-06-20 Ascensia Diabetes Care Holdings Ag Methods and apparatus for information gathering, error detection and analyte concentration determination during continuous analyte sensing
CN112432988B (zh) * 2020-11-25 2023-03-03 重庆迈联医疗科技有限公司 电化学测试系统的温度校正方法
CN114777888B (zh) * 2022-04-28 2024-09-20 四川泛华航空仪表电器有限公司 一种基于光纤光栅压力传感器液位测量误差补偿修正方法
CN119224239B (zh) * 2024-12-02 2025-04-18 无锡零界净化设备股份有限公司 一种用于离线式浓度监测仪的信号增强方法及平台

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
US5243516A (en) 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5352351A (en) 1993-06-08 1994-10-04 Boehringer Mannheim Corporation Biosensing meter with fail/safe procedures to prevent erroneous indications
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
US5723284A (en) 1996-04-01 1998-03-03 Bayer Corporation Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood
AU6157898A (en) 1997-02-06 1998-08-26 E. Heller & Company Small volume (in vitro) analyte sensor
US6391558B1 (en) 1997-03-18 2002-05-21 Andcare, Inc. Electrochemical detection of nucleic acid sequences
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
CA2294610A1 (en) 1997-06-16 1998-12-23 George Moshe Katz Methods of calibrating and testing a sensor for in vivo measurement of an analyte and devices for use in such methods
HU222809B1 (hu) 1997-10-03 2003-10-28 77 Elektronika Műszeripari Kft. Eljárás és készülék kémiai összetevőnek anyagmintából, különösen vér glükóztartalmának vérmintából történő meghatározásához
US7494816B2 (en) * 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
WO1999032881A1 (en) 1997-12-22 1999-07-01 Roche Diagnostics Corporation Meter
ATE258028T1 (de) 1998-05-13 2004-02-15 Cygnus Therapeutic Systems Signalverarbeitung zur messung von physiologischen analyten
US6576117B1 (en) 1998-05-20 2003-06-10 Arkray Method and apparatus for electrochemical measurement using statistical technique
US6475372B1 (en) 2000-02-02 2002-11-05 Lifescan, Inc. Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
JP3655587B2 (ja) 1999-09-20 2005-06-02 ロシュ ダイアグノスティックス コーポレーション 連続アナライトモニタリング用小型バイオセンサー
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
JP4050434B2 (ja) 1999-11-29 2008-02-20 松下電器産業株式会社 サンプルの弁別方法
CN1486423A (zh) 2001-01-17 2004-03-31 ������������ʽ���� 使用传感器的定量分析方法和定量分析装置
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
AU784254B2 (en) 2001-05-21 2006-03-02 Bayer Corporation Improved electrochemical sensor
US6982178B2 (en) 2002-06-10 2006-01-03 E Ink Corporation Components and methods for use in electro-optic displays
US6797150B2 (en) 2001-10-10 2004-09-28 Lifescan, Inc. Determination of sample volume adequacy in biosensor devices
JP4246633B2 (ja) 2001-10-12 2009-04-02 アークレイ株式会社 濃度測定方法および濃度測定装置
CA2419213C (en) 2002-03-07 2011-06-21 Bayer Healthcare Llc Improved electrical sensor
US6964871B2 (en) 2002-04-25 2005-11-15 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
US6946299B2 (en) 2002-04-25 2005-09-20 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
AU2003234944A1 (en) 2002-08-27 2004-03-18 Bayer Healthcare, Llc Methods of Determining Glucose Concentration in Whole Blood Samples
US7132041B2 (en) 2003-02-11 2006-11-07 Bayer Healthcare Llc Methods of determining the concentration of an analyte in a fluid test sample
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
EP1656554B1 (en) 2003-08-21 2018-11-07 AgaMatrix, Inc. Method and apparatus for assay of electrochemical properties
JP4449431B2 (ja) 2003-11-19 2010-04-14 パナソニック株式会社 基質濃度の測定方法
CA2554060C (en) * 2004-02-06 2013-04-16 Bayer Healthcare Llc Electrochemical biosensor
EP1742045B1 (en) 2004-04-19 2016-11-02 Panasonic Healthcare Holdings Co., Ltd. Method for measuring blood components and biosensor and measuring instrument for use therein
RU2006144458A (ru) 2004-05-14 2008-06-20 БАЙЕР ХЕЛТКЭР ЭлЭлСи (US) Способы осуществления корректировки по гематокриту в анализах глюкозы и устройства для этого
CA2887517C (en) 2004-10-12 2017-09-12 Bayer Healthcare Llc Concentration determination in a diffusion barrier layer
GB0428547D0 (en) 2004-12-31 2005-02-09 Euroflow Uk Ltd Methods and apparatus for observing vessel contents
GB0501826D0 (en) 2005-01-28 2005-03-09 Melys Diagnostics Ltd Apparatus for measurement of analyte concentration
JP5009897B2 (ja) 2005-04-08 2012-08-22 バイエル・ヘルスケア・エルエルシー バイオセンサのためのコントロール溶液中の内部基準としての酸化可能種
US7517439B2 (en) 2005-04-15 2009-04-14 Agamatrix, Inc. Error detection in analyte measurements based on measurement of system resistance
KR101321296B1 (ko) 2005-07-20 2013-10-28 바이엘 헬스케어 엘엘씨 게이트형 전류 측정법 온도 결정 방법
KR101477947B1 (ko) 2005-09-30 2014-12-30 바이엘 헬스케어 엘엘씨 게이트형 전압 전류 측정 이온화제 및 헤마토크리트 결정 방법
ES2791724T3 (es) * 2006-02-27 2020-11-05 Ascensia Diabetes Care Holdings Ag Medida de analito ajustada en temperatura para sistemas de biosensor
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
EP2020909A2 (en) 2006-05-08 2009-02-11 Bayer HealthCare LLC Abnormal output detection system for a biosensor
KR101040860B1 (ko) 2006-07-05 2011-06-14 파나소닉 주식회사 액체 시료 측정 방법 및 장치
US20080248581A1 (en) 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
US8101062B2 (en) 2007-07-26 2012-01-24 Nipro Diagnostics, Inc. System and methods for determination of analyte concentration using time resolved amperometry
MX2010000972A (es) * 2007-07-26 2010-03-01 Home Diagnostics Inc Sistema y metodos que determinan concentracion de analito utilizando amperometria resuelta en tiempo.
CN103760356B (zh) 2007-12-10 2019-06-28 安晟信医疗科技控股公司 斜率式补偿
JP5738770B2 (ja) 2008-12-08 2015-06-24 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ 信号調整を持つバイオセンサシステム
BR112012009291A2 (pt) 2009-11-10 2016-05-31 Bayer Healthcare Llc sistema de reconhecimento de subenchimento para um biossensor
SG186179A1 (en) 2010-06-07 2013-01-30 Bayer Healthcare Llc Slope-based compensation including secondary output signals

Also Published As

Publication number Publication date
EP2758039B1 (en) 2018-01-24
US20170360712A1 (en) 2017-12-21
MX350696B (es) 2017-09-14
US10646445B2 (en) 2020-05-12
EP3315123B1 (en) 2019-08-21
TWI600892B (zh) 2017-10-01
US20130071869A1 (en) 2013-03-21
KR20140063829A (ko) 2014-05-27
WO2013043839A1 (en) 2013-03-28
MX2014003015A (es) 2014-05-07
EP2758039A1 (en) 2014-07-30
EP3315123A1 (en) 2018-05-02
ES2757909T3 (es) 2020-04-30
JP2014527186A (ja) 2014-10-09
ES2663097T3 (es) 2018-04-11
EP3586831A1 (en) 2020-01-01
TW201314195A (zh) 2013-04-01
US9775806B2 (en) 2017-10-03

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