MX2014003015A - Biosensor con compensacion de error. - Google Patents

Biosensor con compensacion de error.

Info

Publication number
MX2014003015A
MX2014003015A MX2014003015A MX2014003015A MX2014003015A MX 2014003015 A MX2014003015 A MX 2014003015A MX 2014003015 A MX2014003015 A MX 2014003015A MX 2014003015 A MX2014003015 A MX 2014003015A MX 2014003015 A MX2014003015 A MX 2014003015A
Authority
MX
Mexico
Prior art keywords
function
residual
primary
ssp
error
Prior art date
Application number
MX2014003015A
Other languages
English (en)
Other versions
MX350696B (es
Inventor
Huan-Ping Wu
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of MX2014003015A publication Critical patent/MX2014003015A/es
Publication of MX350696B publication Critical patent/MX350696B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Electrochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Un sistema biosensor determina la concentración de un analito a partir de una señal de salida que es generada a partir de una especie identificable con luz o una reacción de redox del analito. Este biosensor puede determinar por ejemplo la concentración de glucosa en sangre. El sistema biosensor compensa por lo menos 50% del error total en la señal de salida con una función primaria y puede compensar una porción del error residual con por lo menos una función residual. Una función basada en el procesamiento de señales segmentadas (SSP) puede servir como la función primaria, la primera función residual o la segunda función residual. Preferiblemente, cuando la función de SSP sirve como la primera función residual, la función de SSP compensa por lo menos 50% del error residual que permanece después de la compensación primaria. Preferiblemente, cuando la función de SSP sirve como la segunda función residual, la función de SSP compensa por lo menos 50% del error residual que permanece después de la compensación primaria y la primera compensación residual. La compensación de error proporcionada por la función primaria, la primera función residual y la segunda función residual se puede ajustar con coeficientes de ponderación de funciones. La figura más representativa de la invención es la número 1A.
MX2014003015A 2011-09-21 2012-09-20 Biosensor con compensación de error. MX350696B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161537145P 2011-09-21 2011-09-21
PCT/US2012/056280 WO2013043839A1 (en) 2011-09-21 2012-09-20 Biosensor with error compensation

Publications (2)

Publication Number Publication Date
MX2014003015A true MX2014003015A (es) 2014-05-07
MX350696B MX350696B (es) 2017-09-14

Family

ID=47881000

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2014003015A MX350696B (es) 2011-09-21 2012-09-20 Biosensor con compensación de error.

Country Status (8)

Country Link
US (2) US9775806B2 (es)
EP (3) EP2758039B1 (es)
JP (1) JP6082396B2 (es)
KR (1) KR20140063829A (es)
ES (2) ES2663097T3 (es)
MX (1) MX350696B (es)
TW (1) TWI600892B (es)
WO (1) WO2013043839A1 (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2012010860A (es) * 2010-03-22 2013-03-05 Bayer Healthcare Llc Compensacion residual para un biosensor.
JP6305508B2 (ja) * 2013-03-14 2018-04-04 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ 分析物濃度決定の正規化された較正
US10330629B2 (en) 2013-03-14 2019-06-25 Ascensia Diabetes Care Holdings Ag System error compensation of analyte concentration determinations
EP2972398B1 (en) 2013-03-14 2018-12-19 Ascensia Diabetes Care Holdings AG Progressive approximation of sample analyte concentration
US10551362B2 (en) 2013-03-26 2020-02-04 Waters Technologies Corporation Method for extending the dynamic range of absorbance detectors
GB2531728A (en) * 2014-10-27 2016-05-04 Cilag Gmbh Int Method for determining diffusion
CA2984090A1 (en) 2015-05-15 2016-11-24 Ascensia Diabetes Care Holdings Ag Improved biosensor system analyte measurement
US11268925B2 (en) 2016-07-12 2022-03-08 Ascensia Diabetes Care Holdings Ag Intertwined electrical input signals
WO2018104835A1 (en) * 2016-12-05 2018-06-14 Ascensia Diabetes Care Holdings Ag Risk factor monitoring
EP3920798A1 (en) 2019-02-05 2021-12-15 Ascensia Diabetes Care Holdings AG Apparatus and methods for probing sensor operation of continuous analyte sensing and auto-calibration
US11445944B2 (en) 2019-02-22 2022-09-20 Ascensia Diabetes Care Holdings Ag Methods and apparatus for analyte concentration monitoring using harmonic relationships
CN109884150B (zh) * 2019-03-08 2021-05-14 武汉璟泓科技股份有限公司 一种红细胞积压校正方法及存储介质
US11678820B2 (en) 2019-09-10 2023-06-20 Ascensia Diabetes Care Holdings Ag Methods and apparatus for information gathering, error detection and analyte concentration determination during continuous analyte sensing
CN112432988B (zh) * 2020-11-25 2023-03-03 重庆迈联医疗科技有限公司 电化学测试系统的温度校正方法
CN114777888A (zh) * 2022-04-28 2022-07-22 四川泛华航空仪表电器有限公司 一种基于光纤光栅压力传感器液位测量误差补偿修正方法

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431004A (en) 1981-10-27 1984-02-14 Bessman Samuel P Implantable glucose sensor
US4750496A (en) 1987-01-28 1988-06-14 Xienta, Inc. Method and apparatus for measuring blood glucose concentration
US5243516A (en) 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
FR2701117B1 (fr) 1993-02-04 1995-03-10 Asulab Sa Système de mesures électrochimiques à capteur multizones, et son application au dosage du glucose.
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
US5352351A (en) 1993-06-08 1994-10-04 Boehringer Mannheim Corporation Biosensing meter with fail/safe procedures to prevent erroneous indications
IE72524B1 (en) 1994-11-04 1997-04-23 Elan Med Tech Analyte-controlled liquid delivery device and analyte monitor
US6153069A (en) 1995-02-09 2000-11-28 Tall Oak Ventures Apparatus for amperometric Diagnostic analysis
US5582697A (en) 1995-03-17 1996-12-10 Matsushita Electric Industrial Co., Ltd. Biosensor, and a method and a device for quantifying a substrate in a sample liquid using the same
US5620579A (en) * 1995-05-05 1997-04-15 Bayer Corporation Apparatus for reduction of bias in amperometric sensors
US5723284A (en) 1996-04-01 1998-03-03 Bayer Corporation Control solution and method for testing the performance of an electrochemical device for determining the concentration of an analyte in blood
DE69809391T2 (de) 1997-02-06 2003-07-10 Therasense Inc Kleinvolumiger sensor zur in-vitro bestimmung
US6391558B1 (en) 1997-03-18 2002-05-21 Andcare, Inc. Electrochemical detection of nucleic acid sequences
US6391645B1 (en) 1997-05-12 2002-05-21 Bayer Corporation Method and apparatus for correcting ambient temperature effect in biosensors
US5798031A (en) 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
EP0990151A2 (en) 1997-06-16 2000-04-05 ELAN CORPORATION, Plc Methods of calibrating and testing a sensor for (in vivo) measurement of an analyte and devices for use in such methods
HU222809B1 (hu) 1997-10-03 2003-10-28 77 Elektronika Műszeripari Kft. Eljárás és készülék kémiai összetevőnek anyagmintából, különösen vér glükóztartalmának vérmintából történő meghatározásához
DE69840916D1 (de) 1997-12-22 2009-07-30 Roche Diagnostics Operations Messgerät
US7494816B2 (en) * 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
DK1077636T3 (da) 1998-05-13 2004-05-24 Cygnus Therapeutic Systems Signalbehandling til måling af fysiologiske analytter
US6576117B1 (en) 1998-05-20 2003-06-10 Arkray Method and apparatus for electrochemical measurement using statistical technique
US6475372B1 (en) 2000-02-02 2002-11-05 Lifescan, Inc. Electrochemical methods and devices for use in the determination of hematocrit corrected analyte concentrations
CA2305922C (en) 1999-08-02 2005-09-20 Bayer Corporation Improved electrochemical sensor design
CA2385842C (en) 1999-09-20 2008-12-09 Roche Diagnostics Corporation Small volume biosensor for continuous analyte monitoring
US6616819B1 (en) 1999-11-04 2003-09-09 Therasense, Inc. Small volume in vitro analyte sensor and methods
JP4050434B2 (ja) 1999-11-29 2008-02-20 松下電器産業株式会社 サンプルの弁別方法
CN102012389B (zh) 2001-01-17 2013-04-10 爱科来株式会社 使用传感器的定量分析方法和定量分析装置
US6562625B2 (en) 2001-02-28 2003-05-13 Home Diagnostics, Inc. Distinguishing test types through spectral analysis
US6541266B2 (en) 2001-02-28 2003-04-01 Home Diagnostics, Inc. Method for determining concentration of an analyte in a test strip
AU784254B2 (en) 2001-05-21 2006-03-02 Bayer Corporation Improved electrochemical sensor
US6982178B2 (en) 2002-06-10 2006-01-03 E Ink Corporation Components and methods for use in electro-optic displays
US6797150B2 (en) 2001-10-10 2004-09-28 Lifescan, Inc. Determination of sample volume adequacy in biosensor devices
WO2003034055A1 (fr) 2001-10-12 2003-04-24 Arkray, Inc. Procede de mesure de concentration et dispositif de mesure de concentration
CA2419213C (en) 2002-03-07 2011-06-21 Bayer Healthcare Llc Improved electrical sensor
US6964871B2 (en) 2002-04-25 2005-11-15 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
US6946299B2 (en) 2002-04-25 2005-09-20 Home Diagnostics, Inc. Systems and methods for blood glucose sensing
AU2003234944A1 (en) 2002-08-27 2004-03-18 Bayer Healthcare, Llc Methods of Determining Glucose Concentration in Whole Blood Samples
US7132041B2 (en) 2003-02-11 2006-11-07 Bayer Healthcare Llc Methods of determining the concentration of an analyte in a fluid test sample
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
MXPA06001914A (es) 2003-08-21 2006-05-31 Agamatrix Inc Metodo y aparato para ensayo de propiedades electroquimicas.
JP4449431B2 (ja) 2003-11-19 2010-04-14 パナソニック株式会社 基質濃度の測定方法
ATE532063T1 (de) * 2004-02-06 2011-11-15 Bayer Healthcare Llc Elektrochemischer biosensor
CA2559297C (en) 2004-04-19 2012-05-22 Matsushita Electric Industrial Co., Ltd. Method for measuring blood components and biosensor and measuring instrument for use therein
TW200608019A (en) 2004-05-14 2006-03-01 Bayer Healthcare Llc Methods for performing hematocrit adjustment in glucose assays and devices for same
BRPI0516005A (pt) 2004-10-12 2008-08-19 Bayer Healthcare Llc determinação de concentração em uma camada-barreira de difusão
GB0428547D0 (en) 2004-12-31 2005-02-09 Euroflow Uk Ltd Methods and apparatus for observing vessel contents
GB0501826D0 (en) 2005-01-28 2005-03-09 Melys Diagnostics Ltd Apparatus for measurement of analyte concentration
US8002965B2 (en) 2005-04-08 2011-08-23 Bayer Healthcare Llc Oxidizable species as an internal reference in control solutions for biosensors
US7517439B2 (en) 2005-04-15 2009-04-14 Agamatrix, Inc. Error detection in analyte measurements based on measurement of system resistance
CA2890945C (en) 2005-07-20 2016-11-29 Bayer Healthcare Llc Gated amperometry
EP1934591B1 (en) 2005-09-30 2019-01-02 Ascensia Diabetes Care Holdings AG Gated voltammetry
CN101374455B (zh) * 2006-02-27 2013-10-16 拜尔健康护理有限责任公司 用于生物传感器系统的温度调节的分析物测定
US7966859B2 (en) 2006-05-03 2011-06-28 Bayer Healthcare Llc Underfill detection system for a biosensor
JP5121822B2 (ja) 2006-05-08 2013-01-16 バイエル・ヘルスケア・エルエルシー バイオセンサ用異常出力検出システム
JP5018777B2 (ja) * 2006-07-05 2012-09-05 パナソニック株式会社 液体試料測定方法および装置
US20080248581A1 (en) 2007-04-06 2008-10-09 Bayer Healthcare Llc Method for performing correction of blood glucose assay bias using blood hemoglobin concentration
US8101062B2 (en) 2007-07-26 2012-01-24 Nipro Diagnostics, Inc. System and methods for determination of analyte concentration using time resolved amperometry
EP2176653B1 (en) 2007-07-26 2011-09-07 Nipro Diagnostics, Inc. System and methods for determination of analyte concentration using time resolved amperometry
RU2706691C2 (ru) * 2007-12-10 2019-11-20 Асцензия Диабетс Кэар Холдингс АГ Способ определения концентрации аналита
RU2509304C2 (ru) * 2008-12-08 2014-03-10 БАЙЕР ХЕЛТКЭА ЭлЭлСи Биосенсорная система с корректировкой сигнала
CA2776332C (en) 2009-11-10 2018-05-01 Bayer Healthcare Llc Underfill recognition system for a biosensor
JP5856154B2 (ja) 2010-06-07 2016-02-09 バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅＬＬＣ 二次出力シグナルを含む勾配に基づく補正

Also Published As

Publication number Publication date
JP2014527186A (ja) 2014-10-09
EP2758039A1 (en) 2014-07-30
KR20140063829A (ko) 2014-05-27
TW201314195A (zh) 2013-04-01
US10646445B2 (en) 2020-05-12
US9775806B2 (en) 2017-10-03
WO2013043839A1 (en) 2013-03-28
EP3315123B1 (en) 2019-08-21
US20130071869A1 (en) 2013-03-21
ES2757909T3 (es) 2020-04-30
TWI600892B (zh) 2017-10-01
MX350696B (es) 2017-09-14
US20170360712A1 (en) 2017-12-21
ES2663097T3 (es) 2018-04-11
EP2758039B1 (en) 2018-01-24
EP3315123A1 (en) 2018-05-02
EP3586831A1 (en) 2020-01-01
JP6082396B2 (ja) 2017-02-15

Similar Documents

Publication Publication Date Title
MX350696B (es) Biosensor con compensación de error.
MX368104B (es) Compensacion residual para un biosensor.
MX2010006392A (es) Compensacion basada en la pendiente.
MX340921B (es) Compensacion basada en la pendiente que incluye señales de salida secundarias.
WO2011119201A3 (en) Calibration of glucose monitoring sensor and/or insulin delivery system
WO2017044654A8 (en) Transcutaneous analyte sensors and monitors, calibration thereof, and associated methods
EP4218570A3 (en) Polymer membranes for continuous analyte sensors
MX2010008920A (es) Estabilizacion de deshidrogenasas utilizando coenzimas estables.
WO2010062627A3 (en) Biosensors based on optical probing and sensing
MX367439B (es) Sistema de gestion de llenado insuficiente para un biosensor.
MX2010014228A (es) Metodos y productos de diagnostico del p/gf-1 acompañante.
WO2010055155A3 (en) Assessing a subject's circulatory system
NZ597628A (en) Hla-b5801 allele associated with adverse drug reactions and methods for detecting such
WO2009031045A3 (en) Anti-chikungunya monoclonal antibodies and uses thereof
WO2008131361A3 (en) Biosensors for measuring analytes in the interstitial fluid
WO2012145142A3 (en) Control of electronic device using nerve analysis
GB0711327D0 (en) Diagnostic method
MY173855A (en) Amperometric biosensor for histamine determination
MX357655B (es) Mediador soluble.
GB201113435D0 (en) Sensor calibration
ATE530966T1 (de) Auftriebsmessung
WO2007037910A3 (en) Specific removal of activated immune cells
TW200703537A (en) Substrate processing apparatus and substrate housing method
WO2008059041A3 (en) Complementation of factor xi deficiency by factor v mutants
Manju et al. Relationship between glycosylated hemoglobin, serum nitric oxide and mean arterial blood pressure

Legal Events

Date Code Title Description
GB Transfer or assignment

Owner name: ASCENSIA DIABETES CARE HOLDINGS AG

FG Grant or registration