JP6054405B2 - 培養期間を用いた磁性粒子の検出 - Google Patents

培養期間を用いた磁性粒子の検出 Download PDF

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Publication number
JP6054405B2
JP6054405B2 JP2014536360A JP2014536360A JP6054405B2 JP 6054405 B2 JP6054405 B2 JP 6054405B2 JP 2014536360 A JP2014536360 A JP 2014536360A JP 2014536360 A JP2014536360 A JP 2014536360A JP 6054405 B2 JP6054405 B2 JP 6054405B2
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detection surface
magnetic particles
culture period
sensor device
sample chamber
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Japanese (ja)
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JP2014531029A (ja
Inventor
シッケ フォッペン
シッケ フォッペン
ベルナルドス ヨセフ マリア ベールリンフ
ベルナルドス ヨセフ マリア ベールリンフ
クール ウィレミナ マリア フイネン
クール ウィレミナ マリア フイネン
フラーフ ヘンドリク ヤン デ
フラーフ ヘンドリク ヤン デ
ファン デ ウィール ダニーレ ワルテラ マリア ケムペール
ファン デ ウィール ダニーレ ワルテラ マリア ケムペール
ローランド アントニウス ヨハネス ヘラルドス スミッツ
ローランド アントニウス ヨハネス ヘラルドス スミッツ
アルベルト ヘンドリク ヤン イミンク
アルベルト ヘンドリク ヤン イミンク
ティエ フェムケ カリナ デ
ティエ フェムケ カリナ デ
ウエンデラ メールテンス
ウエンデラ メールテンス
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Koninklijke Philips NV
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Koninklijke Philips NV
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/064—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Measuring devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
    • A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6804—Garments; Clothes
    • A61B5/6805—Vests, e.g. shirts or gowns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Fluid Mechanics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Dispersion Chemistry (AREA)
  • Human Computer Interaction (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physiology (AREA)
  • Dentistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2014536360A 2011-10-20 2012-10-05 培養期間を用いた磁性粒子の検出 Active JP6054405B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161549428P 2011-10-20 2011-10-20
US61/549,428 2011-10-20
PCT/IB2012/055355 WO2013057616A1 (en) 2011-10-20 2012-10-05 Magnetic particle detection with incubation period

Publications (2)

Publication Number Publication Date
JP2014531029A JP2014531029A (ja) 2014-11-20
JP6054405B2 true JP6054405B2 (ja) 2016-12-27

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JP2014536360A Active JP6054405B2 (ja) 2011-10-20 2012-10-05 培養期間を用いた磁性粒子の検出

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Country Link
US (2) US10031132B2 (cg-RX-API-DMAC7.html)
EP (1) EP2745118B1 (cg-RX-API-DMAC7.html)
JP (1) JP6054405B2 (cg-RX-API-DMAC7.html)
CN (1) CN103890588B (cg-RX-API-DMAC7.html)
IN (1) IN2014CN02659A (cg-RX-API-DMAC7.html)
WO (1) WO2013057616A1 (cg-RX-API-DMAC7.html)

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* Cited by examiner, † Cited by third party
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CN105266765A (zh) * 2014-11-10 2016-01-27 北京至感传感器技术研究院有限公司 用于检测乳房生理变化的装置
US10226219B2 (en) * 2015-05-11 2019-03-12 Elwha Llc Interactive surgical drape, system, and related methods
US10235737B2 (en) * 2015-05-11 2019-03-19 Elwha Llc Interactive surgical drape, system, and related methods
CN105929149B (zh) * 2016-04-26 2018-09-11 中国科学院电子学研究所 一种基于磁富集和全内反射的光学检测仪
JP7455529B2 (ja) * 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定装置の制御方法
US11136543B1 (en) 2020-02-11 2021-10-05 Edward R. Flynn Magnetic cell incubation device
WO2024057310A1 (en) * 2022-09-13 2024-03-21 Marrow Wiz Ltd. Entry point identification system

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US6319670B1 (en) * 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
JP3647587B2 (ja) * 1997-01-20 2005-05-11 シスメックス株式会社 免疫測定法
US6180418B1 (en) * 1998-01-20 2001-01-30 The United States Of America As Represented By The Secretary Of The Navy Force discrimination assay
US6816266B2 (en) * 2000-02-08 2004-11-09 Deepak Varshneya Fiber optic interferometric vital sign monitor for use in magnetic resonance imaging, confined care facilities and in-hospital
WO2003067258A1 (fr) 2002-01-29 2003-08-14 Asahi Kasei Kabushiki Kaisha Biocapteur, procede de mesure de molecules magnetiques et procede de mesure de l'objet mesure
US7736889B2 (en) * 2003-06-10 2010-06-15 The United States Of America As Represented By The Secretary Of The Navy Fluidic force discrimination
FR2858758B1 (fr) * 2003-08-14 2006-04-07 Tam Telesante Sarl Systeme de surveillance medicale au moyen d'un vetement
JP2009508103A (ja) * 2005-09-08 2009-02-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ マイクロセンサ装置
US8637317B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
JP2009544033A (ja) * 2006-07-17 2009-12-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ センサ表面に対する磁性物体又は磁化可能物体の引き付け及び引き離し
WO2008017972A2 (en) 2006-08-09 2008-02-14 Koninklijke Philips Electronics N. V. A magnet system for biosensors
EP2125215B1 (en) * 2007-03-21 2019-05-08 University Of The West Of England, Bristol Particle facilitated testing
WO2008142492A1 (en) * 2007-05-22 2008-11-27 Koninklijke Philips Electronics N.V. Method for detecting label particles
EP2160592A1 (en) 2007-06-21 2010-03-10 Koninklijke Philips Electronics N.V. Microelectronic sensor device with light source and light detector
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
JP2011508199A (ja) * 2007-12-20 2011-03-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 標的粒子を検出するためのマイクロエレクトロニクスセンサデバイス
WO2010042242A1 (en) 2008-10-10 2010-04-15 Rutgers, The State University Of New Jersey Methods and related devices for continuous sensing utilizing magnetic beads
CN102187241B (zh) * 2008-10-17 2015-11-25 皇家飞利浦电子股份有限公司 用于灵敏测定的脉冲磁激励
JP2013503352A (ja) * 2009-08-31 2013-01-31 エムバイオ ダイアグノスティクス，インコーポレイティド 統合されたサンプル調製及び検体検出
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Also Published As

Publication number Publication date
WO2013057616A1 (en) 2013-04-25
EP2745118B1 (en) 2020-12-09
US20140329335A1 (en) 2014-11-06
EP2745118A1 (en) 2014-06-25
US10031132B2 (en) 2018-07-24
US20140323856A1 (en) 2014-10-30
CN103890588A (zh) 2014-06-25
CN103890588B (zh) 2017-02-15
JP2014531029A (ja) 2014-11-20
IN2014CN02659A (cg-RX-API-DMAC7.html) 2015-06-26

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