IN2014CN02659A - - Google Patents

Info

Publication number
IN2014CN02659A
IN2014CN02659A IN2659CHN2014A IN2014CN02659A IN 2014CN02659 A IN2014CN02659 A IN 2014CN02659A IN 2659CHN2014 A IN2659CHN2014 A IN 2659CHN2014A IN 2014CN02659 A IN2014CN02659 A IN 2014CN02659A
Authority
IN
India
Prior art keywords
sample
magnetic particles
incubation
sample chamber
sensing surface
Prior art date
Application number
Inventor
Sytske Foppen
Bernardus Jozef Maria Beerling
Keur Willemina Maria Huijnen
Graaf Hendrik Jan De
Van De Wiel Danielle Walthera Maria Kemper
Roland Antonius Johannes Gerardus Smits
Albert Hendrik Jan Immink
Theije Femke Karina De
Wendela Meertens
Original Assignee
Koninkl Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Nv filed Critical Koninkl Philips Nv
Publication of IN2014CN02659A publication Critical patent/IN2014CN02659A/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/064—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using markers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/103—Detecting, measuring or recording devices for testing the shape, pattern, colour, size or movement of the body or parts thereof, for diagnostic purposes
    • A61B5/11—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb
    • A61B5/113—Measuring movement of the entire body or parts thereof, e.g. head or hand tremor, mobility of a limb occurring during breathing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/6804—Garments; Clothes
    • A61B5/6805—Vests
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient ; user input means
    • A61B5/742—Details of notification to user or communication with user or patient ; user input means using visual displays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0647—Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668—Trapping microscopic beads
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0877—Flow chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/043—Moving fluids with specific forces or mechanical means specific forces magnetic forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Clinical Laboratory Science (AREA)
  • Fluid Mechanics (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Dentistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Human Computer Interaction (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Physiology (AREA)
  • Microbiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The invention relates to a method and a device for the detection of magnetic particles (1) in a sample chamber (112). After introduction of the sample into said sample chamber (112) the magnetic particles (1) are first retained within the sample chamber (112) and kept away from the sensing surface (111) by an appropriate magnetic field (B) to allow for an incubation of the sample with reagents. A reference measurement may be made during this incubation period (T) preferably at the end thereof. After incubation the magnetic particles (1) are allowed to contact the sensing surface (111) where a target measurement can be conducted.
IN2659CHN2014 2011-10-20 2012-10-05 IN2014CN02659A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161549428P 2011-10-20 2011-10-20
PCT/IB2012/055355 WO2013057616A1 (en) 2011-10-20 2012-10-05 Magnetic particle detection with incubation period

Publications (1)

Publication Number Publication Date
IN2014CN02659A true IN2014CN02659A (en) 2015-06-26

Family

ID=47227982

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2659CHN2014 IN2014CN02659A (en) 2011-10-20 2012-10-05

Country Status (6)

Country Link
US (2) US10031132B2 (en)
EP (1) EP2745118B1 (en)
JP (1) JP6054405B2 (en)
CN (1) CN103890588B (en)
IN (1) IN2014CN02659A (en)
WO (1) WO2013057616A1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105266765A (en) * 2014-11-10 2016-01-27 北京至感传感器技术研究院有限公司 Device for detecting physiological changes of breasts
US10235737B2 (en) * 2015-05-11 2019-03-19 Elwha Llc Interactive surgical drape, system, and related methods
US10226219B2 (en) * 2015-05-11 2019-03-12 Elwha Llc Interactive surgical drape, system, and related methods
CN105929149B (en) * 2016-04-26 2018-09-11 中国科学院电子学研究所 A kind of optical detector based on magnetic enrichment and total internal reflection
JP7455529B2 (en) * 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 Sample measuring device and method for controlling the sample measuring device
US11136543B1 (en) 2020-02-11 2021-10-05 Edward R. Flynn Magnetic cell incubation device
WO2024057310A1 (en) * 2022-09-13 2024-03-21 Marrow Wiz Ltd. Entry point identification system

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6319670B1 (en) * 1995-05-09 2001-11-20 Meso Scale Technology Llp Methods and apparatus for improved luminescence assays using microparticles
JP3647587B2 (en) * 1997-01-20 2005-05-11 シスメックス株式会社 Immunoassay
US6180418B1 (en) * 1998-01-20 2001-01-30 The United States Of America As Represented By The Secretary Of The Navy Force discrimination assay
US6816266B2 (en) * 2000-02-08 2004-11-09 Deepak Varshneya Fiber optic interferometric vital sign monitor for use in magnetic resonance imaging, confined care facilities and in-hospital
JP4240303B2 (en) 2002-01-29 2009-03-18 旭化成株式会社 Biosensor, magnetic molecule measuring method, and measuring object measuring method
US7736889B2 (en) * 2003-06-10 2010-06-15 The United States Of America As Represented By The Secretary Of The Navy Fluidic force discrimination
FR2858758B1 (en) * 2003-08-14 2006-04-07 Tam Telesante Sarl MEDICAL MONITORING SYSTEM USING A CLOTHING
EP1926994A1 (en) * 2005-09-08 2008-06-04 Koninklijke Philips Electronics N.V. Microsensor device
US8637317B2 (en) 2006-04-18 2014-01-28 Advanced Liquid Logic, Inc. Method of washing beads
WO2008010110A1 (en) * 2006-07-17 2008-01-24 Koninklijke Philips Electronics N. V. Attraction and repulsion of magnetic of magnetizable objects to and from a sensor surface
CN101501519A (en) 2006-08-09 2009-08-05 皇家飞利浦电子股份有限公司 A magnet system for biosensors
US9610584B2 (en) * 2007-03-21 2017-04-04 University Of The West Of England, Bristol Particle facilitated testing
WO2008142492A1 (en) 2007-05-22 2008-11-27 Koninklijke Philips Electronics N.V. Method for detecting label particles
WO2008155723A1 (en) 2007-06-21 2008-12-24 Koninklijke Philips Electronics N. V. Microelectronic sensor device with light source and light detector
EP2017618A1 (en) * 2007-07-20 2009-01-21 Koninklijke Philips Electronics N.V. Methods and systems for detecting
CN101903758B (en) * 2007-12-20 2013-05-08 皇家飞利浦电子股份有限公司 Microelectronic sensor device for the detection of target particles
WO2010042242A1 (en) 2008-10-10 2010-04-15 Rutgers, The State University Of New Jersey Methods and related devices for continuous sensing utilizing magnetic beads
CN102187241B (en) * 2008-10-17 2015-11-25 皇家飞利浦电子股份有限公司 Pulsed magnetic for sensitive determination encourages
EP2473595A4 (en) * 2009-08-31 2013-04-24 Mbio Diagnostics Inc Integrated sample preparation and analyte detection
US9075052B2 (en) 2009-09-28 2015-07-07 Koninklijke Philips N.V. Biosensor system for single particle detection
US20130115715A1 (en) * 2010-05-27 2013-05-09 Episentec Ab Method of sensor measurement
EP2586041A1 (en) 2010-06-22 2013-05-01 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
US20120077184A1 (en) * 2010-09-28 2012-03-29 Starkdx Incorporated Electromagnetic multiplex assay biosensor

Also Published As

Publication number Publication date
JP6054405B2 (en) 2016-12-27
US10031132B2 (en) 2018-07-24
CN103890588B (en) 2017-02-15
US20140323856A1 (en) 2014-10-30
EP2745118A1 (en) 2014-06-25
US20140329335A1 (en) 2014-11-06
JP2014531029A (en) 2014-11-20
EP2745118B1 (en) 2020-12-09
WO2013057616A1 (en) 2013-04-25
CN103890588A (en) 2014-06-25

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