JP6046609B2 - 皮膚ケア製品の送達 - Google Patents
皮膚ケア製品の送達 Download PDFInfo
- Publication number
- JP6046609B2 JP6046609B2 JP2013514498A JP2013514498A JP6046609B2 JP 6046609 B2 JP6046609 B2 JP 6046609B2 JP 2013514498 A JP2013514498 A JP 2013514498A JP 2013514498 A JP2013514498 A JP 2013514498A JP 6046609 B2 JP6046609 B2 JP 6046609B2
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- Prior art keywords
- magnetic
- dipole
- active agent
- pairs
- skin
- Prior art date
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- 230000005291 magnetic effect Effects 0.000 claims description 312
- 239000013543 active substance Substances 0.000 claims description 124
- 210000003491 skin Anatomy 0.000 claims description 84
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 75
- 230000008591 skin barrier function Effects 0.000 claims description 67
- 238000000034 method Methods 0.000 claims description 57
- 230000004907 flux Effects 0.000 claims description 47
- 239000004202 carbamide Substances 0.000 claims description 38
- 235000013877 carbamide Nutrition 0.000 claims description 38
- 239000003795 chemical substances by application Substances 0.000 claims description 30
- 230000033001 locomotion Effects 0.000 claims description 24
- 239000002537 cosmetic Substances 0.000 claims description 22
- 210000002615 epidermis Anatomy 0.000 claims description 20
- 230000005292 diamagnetic effect Effects 0.000 claims description 19
- 239000000499 gel Substances 0.000 claims description 17
- 210000000434 stratum corneum Anatomy 0.000 claims description 16
- 230000001965 increasing effect Effects 0.000 claims description 14
- 230000004044 response Effects 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 11
- 238000009792 diffusion process Methods 0.000 claims description 10
- 239000004909 Moisturizer Substances 0.000 claims description 9
- -1 cholesterol Chemical compound 0.000 claims description 9
- 230000001333 moisturizer Effects 0.000 claims description 9
- 239000000126 substance Substances 0.000 claims description 9
- 150000001875 compounds Chemical class 0.000 claims description 8
- 239000003981 vehicle Substances 0.000 claims description 7
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 6
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 6
- 239000002781 deodorant agent Substances 0.000 claims description 6
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims description 5
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims description 5
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- INAXVXBDKKUCGI-UHFFFAOYSA-N 4-hydroxy-2,5-dimethylfuran-3-one Chemical compound CC1OC(C)=C(O)C1=O INAXVXBDKKUCGI-UHFFFAOYSA-N 0.000 claims description 4
- QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 claims description 4
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- 150000001298 alcohols Chemical class 0.000 claims description 4
- 229910052782 aluminium Inorganic materials 0.000 claims description 4
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 claims description 4
- 239000002738 chelating agent Substances 0.000 claims description 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims description 4
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 4
- RXKJFZQQPQGTFL-UHFFFAOYSA-N dihydroxyacetone Chemical compound OCC(=O)CO RXKJFZQQPQGTFL-UHFFFAOYSA-N 0.000 claims description 4
- RRAFCDWBNXTKKO-UHFFFAOYSA-N eugenol Chemical compound COC1=CC(CC=C)=CC=C1O RRAFCDWBNXTKKO-UHFFFAOYSA-N 0.000 claims description 4
- 239000000194 fatty acid Substances 0.000 claims description 4
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- 150000001261 hydroxy acids Chemical class 0.000 claims description 4
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
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- 239000001993 wax Substances 0.000 claims description 4
- XEFQLINVKFYRCS-UHFFFAOYSA-N Triclosan Chemical compound OC1=CC(Cl)=CC=C1OC1=CC=C(Cl)C=C1Cl XEFQLINVKFYRCS-UHFFFAOYSA-N 0.000 claims description 3
- ZGUQGPFMMTZGBQ-UHFFFAOYSA-N [Al].[Al].[Zr] Chemical compound [Al].[Al].[Zr] ZGUQGPFMMTZGBQ-UHFFFAOYSA-N 0.000 claims description 3
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- 235000011187 glycerol Nutrition 0.000 claims description 3
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- DBSABEYSGXPBTA-RXSVEWSESA-N (2r)-2-[(1s)-1,2-dihydroxyethyl]-3,4-dihydroxy-2h-furan-5-one;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@H](O)[C@H]1OC(=O)C(O)=C1O DBSABEYSGXPBTA-RXSVEWSESA-N 0.000 claims description 2
- NDVRKEKNSBMTAX-MVNLRXSJSA-N (2s,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal;phosphoric acid Chemical compound OP(O)(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)C=O NDVRKEKNSBMTAX-MVNLRXSJSA-N 0.000 claims description 2
- DSSYKIVIOFKYAU-XCBNKYQSSA-N (R)-camphor Chemical compound C1C[C@@]2(C)C(=O)C[C@@H]1C2(C)C DSSYKIVIOFKYAU-XCBNKYQSSA-N 0.000 claims description 2
- UOQHWNPVNXSDDO-UHFFFAOYSA-N 3-bromoimidazo[1,2-a]pyridine-6-carbonitrile Chemical compound C1=CC(C#N)=CN2C(Br)=CN=C21 UOQHWNPVNXSDDO-UHFFFAOYSA-N 0.000 claims description 2
- 244000144927 Aloe barbadensis Species 0.000 claims description 2
- 235000002961 Aloe barbadensis Nutrition 0.000 claims description 2
- 244000144730 Amygdalus persica Species 0.000 claims description 2
- NPBVQXIMTZKSBA-UHFFFAOYSA-N Chavibetol Natural products COC1=CC=C(CC=C)C=C1O NPBVQXIMTZKSBA-UHFFFAOYSA-N 0.000 claims description 2
- 241000723346 Cinnamomum camphora Species 0.000 claims description 2
- 244000060011 Cocos nucifera Species 0.000 claims description 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 2
- XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 claims description 2
- 241000402754 Erythranthe moschata Species 0.000 claims description 2
- 239000005770 Eugenol Substances 0.000 claims description 2
- 240000004670 Glycyrrhiza echinata Species 0.000 claims description 2
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 2
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 2
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 2
- 241000208680 Hamamelis mollis Species 0.000 claims description 2
- XPPALVZZCMPTIV-ARJAWSKDSA-N Jasmine lactone Chemical compound CC\C=C/CC1CCCC(=O)O1 XPPALVZZCMPTIV-ARJAWSKDSA-N 0.000 claims description 2
- XPPALVZZCMPTIV-UHFFFAOYSA-N Jasmine lactone Natural products CCC=CCC1CCCC(=O)O1 XPPALVZZCMPTIV-UHFFFAOYSA-N 0.000 claims description 2
- 239000004166 Lanolin Substances 0.000 claims description 2
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 claims description 2
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 claims description 2
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- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 claims description 2
- LQKRYVGRPXFFAV-UHFFFAOYSA-N Phenylmethylglycidic ester Chemical compound CCOC(=O)C1OC1(C)C1=CC=CC=C1 LQKRYVGRPXFFAV-UHFFFAOYSA-N 0.000 claims description 2
- 235000006040 Prunus persica var persica Nutrition 0.000 claims description 2
- UVMRYBDEERADNV-UHFFFAOYSA-N Pseudoeugenol Natural products COC1=CC(C(C)=C)=CC=C1O UVMRYBDEERADNV-UHFFFAOYSA-N 0.000 claims description 2
- 229930182558 Sterol Natural products 0.000 claims description 2
- UJNOLBSYLSYIBM-WISYIIOYSA-N [(1r,2s,5r)-5-methyl-2-propan-2-ylcyclohexyl] (2r)-2-hydroxypropanoate Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@H]1OC(=O)[C@@H](C)O UJNOLBSYLSYIBM-WISYIIOYSA-N 0.000 claims description 2
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- 229940061720 alpha hydroxy acid Drugs 0.000 claims description 2
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- AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims description 2
- DNXNYEBMOSARMM-UHFFFAOYSA-N alumane;zirconium Chemical class [AlH3].[Zr] DNXNYEBMOSARMM-UHFFFAOYSA-N 0.000 claims description 2
- 235000011124 aluminium ammonium sulphate Nutrition 0.000 claims description 2
- 235000011126 aluminium potassium sulphate Nutrition 0.000 claims description 2
- LCQXXBOSCBRNNT-UHFFFAOYSA-K ammonium aluminium sulfate Chemical compound [NH4+].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O LCQXXBOSCBRNNT-UHFFFAOYSA-K 0.000 claims description 2
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- 229940071097 ascorbyl phosphate Drugs 0.000 claims description 2
- XNEFYCZVKIDDMS-UHFFFAOYSA-N avobenzone Chemical compound C1=CC(OC)=CC=C1C(=O)CC(=O)C1=CC=C(C(C)(C)C)C=C1 XNEFYCZVKIDDMS-UHFFFAOYSA-N 0.000 claims description 2
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- LVYZJEPLMYTTGH-UHFFFAOYSA-H dialuminum chloride pentahydroxide dihydrate Chemical compound [Cl-].[Al+3].[OH-].[OH-].[Al+3].[OH-].[OH-].[OH-].O.O LVYZJEPLMYTTGH-UHFFFAOYSA-H 0.000 claims description 2
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N2/00—Magnetotherapy
- A61N2/002—Magnetotherapy in combination with another treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Medical Informatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
- Magnetic Treatment Devices (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2010902650A AU2010902650A0 (en) | 2010-06-17 | Delivery of Skin Care Products | |
| AU2010902650 | 2010-06-17 | ||
| PCT/AU2011/000735 WO2011156869A1 (en) | 2010-06-17 | 2011-06-17 | Delivery of skin care products |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013534842A JP2013534842A (ja) | 2013-09-09 |
| JP2013534842A5 JP2013534842A5 (OSRAM) | 2014-08-14 |
| JP6046609B2 true JP6046609B2 (ja) | 2016-12-21 |
Family
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|---|---|---|---|
| JP2013514498A Active JP6046609B2 (ja) | 2010-06-17 | 2011-06-17 | 皮膚ケア製品の送達 |
Country Status (4)
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|---|---|
| US (1) | US9463330B2 (OSRAM) |
| EP (1) | EP2582424A4 (OSRAM) |
| JP (1) | JP6046609B2 (OSRAM) |
| WO (1) | WO2011156869A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2806940B1 (en) * | 2012-01-24 | 2019-05-22 | International Scientific PTY Ltd | Delivery device |
| EP3154552B1 (en) * | 2014-06-11 | 2021-03-24 | International Scientific Pty Ltd | Device and method to treat or prevent joint degeneration |
| WO2016044567A1 (en) | 2014-09-17 | 2016-03-24 | The Procter & Gamble Company | Skin care products |
| US10034827B2 (en) * | 2014-09-17 | 2018-07-31 | The Procter & Gamble Company | Skin care product and method of use |
| EP3200865B1 (en) | 2014-09-17 | 2020-12-23 | The Procter and Gamble Company | Skin care applicator |
| JP6858506B2 (ja) * | 2016-08-09 | 2021-04-14 | ロレアル | 改善された経皮浸透のための化粧用器具及びその製造方法 |
| JP2018126390A (ja) * | 2017-02-09 | 2018-08-16 | 維聡 榊原 | 外用成分経皮吸収促進用具 |
| JP6810278B2 (ja) * | 2017-03-16 | 2021-01-06 | ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ | スキンケアアプリケータ |
| WO2019033160A1 (en) * | 2017-08-14 | 2019-02-21 | International Scientific Pty Ltd | ENHANCED PENETRATION OF ACTIVE AGENTS |
| CA3069999A1 (en) * | 2017-08-18 | 2019-02-21 | The Procter & Gamble Company | Skin care products |
| USD846751S1 (en) | 2017-08-23 | 2019-04-23 | The Procter And Gamble Company | Cosmetic skin care device |
| US11717696B2 (en) | 2017-10-31 | 2023-08-08 | Otomagnetics, Inc. | Magnetically-assisted delivery into and through the skin |
| WO2020010389A1 (en) * | 2018-07-13 | 2020-01-16 | International Scientific Pty Ltd | A method and apparatus for enhanced transdermal, intradermal or transappendageal delivery of titanium dioxide |
| ES2788800B2 (es) * | 2019-04-22 | 2021-04-29 | De La Cal Antonio Madronero | Recipiente para acondicionar aceites vegetales mediante la utilización de campos magnéticos y método de aplicación para cosmética. |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4180646A (en) | 1975-01-28 | 1979-12-25 | Alza Corporation | Novel orthoester polymers and orthocarbonate polymers |
| US4093709A (en) | 1975-01-28 | 1978-06-06 | Alza Corporation | Drug delivery devices manufactured from poly(orthoesters) and poly(orthocarbonates) |
| US4131648A (en) | 1975-01-28 | 1978-12-26 | Alza Corporation | Structured orthoester and orthocarbonate drug delivery devices |
| JPS51125888U (OSRAM) * | 1975-04-04 | 1976-10-12 | ||
| US4079038A (en) | 1976-03-05 | 1978-03-14 | Alza Corporation | Poly(carbonates) |
| US4304767A (en) | 1980-05-15 | 1981-12-08 | Sri International | Polymers of di- (and higher functionality) ketene acetals and polyols |
| JPS5957951U (ja) * | 1982-10-08 | 1984-04-16 | 株式会社井上ジャパックス研究所 | ブラシ |
| US4502497A (en) | 1983-01-28 | 1985-03-05 | Joseph Siahou | Toothbrush for polarizing the active ingredients of toothpaste |
| JPS59149480A (ja) | 1983-02-16 | 1984-08-27 | Sharp Corp | 文字放送受信機 |
| JPS6036727U (ja) | 1983-08-19 | 1985-03-13 | 栃木精工株式会社 | 歯ブラシ |
| JPS6088825A (ja) | 1983-10-21 | 1985-05-18 | Kawasaki Heavy Ind Ltd | エンジンガバナ− |
| JPS61196756A (ja) | 1985-02-25 | 1986-08-30 | Hitachi Metals Ltd | リニアパルスモ−タ |
| US4946931A (en) | 1989-06-14 | 1990-08-07 | Pharmaceutical Delivery Systems, Inc. | Polymers containing carboxy-ortho ester and ortho ester linkages |
| JPH0614813A (ja) | 1990-12-12 | 1994-01-25 | Yao Shoko Kaigishiyo | 磁気歯ブラシ |
| JPH0546200A (ja) | 1991-08-14 | 1993-02-26 | Toshiba Corp | 音声記録再生装置 |
| US6383129B1 (en) * | 1999-07-14 | 2002-05-07 | Nu-Magnetics, Inc. | Magnetotherapeutic device with bio-ceramic fibers |
| WO2000023144A1 (en) | 1995-04-23 | 2000-04-27 | Electromagnetic Bracing Systems, Inc. | Transdermal active drug delivery system and method |
| US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
| US5968543A (en) | 1996-01-05 | 1999-10-19 | Advanced Polymer Systems, Inc. | Polymers with controlled physical state and bioerodibility |
| US5735942A (en) | 1996-02-07 | 1998-04-07 | Usbiomaterials Corporation | Compositions containing bioactive glass and their use in treating tooth hypersensitivity |
| US5785956A (en) | 1996-06-07 | 1998-07-28 | Colgate Palmolive Company | Dual component dentifrice composition for dental fluoridation |
| US6461288B1 (en) | 1996-09-10 | 2002-10-08 | Holcomb Healthcare Services | Method and apparatus for altering the charge distribution upon living membranes with functional stabilization of the membrane physical electrical integrity |
| US5800685A (en) | 1996-10-28 | 1998-09-01 | Cardiotronics Systems, Inc. | Electrically conductive adhesive hydrogels |
| JPH10192419A (ja) | 1997-01-07 | 1998-07-28 | Hiroshi Fukuba | 血行促進器 |
| JPH11113638A (ja) | 1997-10-16 | 1999-04-27 | Yoshiro Nakamatsu | 薄小型磁場歯ブラシ |
| JP2000197709A (ja) * | 1998-10-29 | 2000-07-18 | Unilever Nv | スキンケア化粧システム及び方法 |
| ATE256421T1 (de) | 1999-05-25 | 2004-01-15 | Medicotest As | Hautelektrode |
| WO2001010421A1 (en) | 1999-08-06 | 2001-02-15 | Board Of Regents, The University Of Texas System | Drug releasing biodegradable fiber implant |
| US6613355B2 (en) | 2000-05-11 | 2003-09-02 | A.P. Pharma, Inc. | Semi-solid delivery vehicle and pharmaceutical compositions |
| US6631294B2 (en) | 2001-06-01 | 2003-10-07 | Biofisica, Llc | Apparatus and methods for facilitating wound healing |
| EP1404245A4 (en) * | 2001-07-12 | 2006-04-05 | Water Pik Inc | TWO-TONE ORAL HYGIENE DEVICE |
| US6524606B1 (en) | 2001-11-16 | 2003-02-25 | Ap Pharma, Inc. | Bioerodible polyorthoesters containing amine groups |
| ATE252334T1 (de) * | 2002-02-21 | 2003-11-15 | Grital Group Anstalt | Zahnbürste mit magnetelementen |
| AT7445U3 (de) | 2004-11-16 | 2005-10-17 | Karl Peter May | Magnetische zahnbürste |
| US20060115785A1 (en) | 2004-11-30 | 2006-06-01 | Chunhua Li | Systems and methods for intra-oral drug delivery |
| JP5046200B2 (ja) | 2006-04-17 | 2012-10-10 | トヨタ自動車株式会社 | 転造工具 |
| WO2009046345A1 (en) | 2007-10-05 | 2009-04-09 | Worthington, W. Bradley | Magnetophoresis apparatus and method of use |
| EP2303393A4 (en) | 2008-05-07 | 2011-10-19 | Obj Ltd | METHOD AND APPARATUS FOR ENHANCED TRANSDERMAL DIFFUSION |
| US8316862B2 (en) | 2009-02-25 | 2012-11-27 | University Of Maryland | Devices, systems and methods for magnetic-assisted therapeutic agent delivery |
-
2011
- 2011-06-17 EP EP11794962.8A patent/EP2582424A4/en not_active Withdrawn
- 2011-06-17 WO PCT/AU2011/000735 patent/WO2011156869A1/en not_active Ceased
- 2011-06-17 US US13/704,157 patent/US9463330B2/en active Active
- 2011-06-17 JP JP2013514498A patent/JP6046609B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2582424A1 (en) | 2013-04-24 |
| WO2011156869A1 (en) | 2011-12-22 |
| EP2582424A4 (en) | 2014-08-06 |
| JP2013534842A (ja) | 2013-09-09 |
| US20130144109A1 (en) | 2013-06-06 |
| US9463330B2 (en) | 2016-10-11 |
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Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
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| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |