JP6031122B2 - 抗微生物療法のための三環式ホウ素化合物 - Google Patents

抗微生物療法のための三環式ホウ素化合物 Download PDF

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JP6031122B2
JP6031122B2 JP2014548243A JP2014548243A JP6031122B2 JP 6031122 B2 JP6031122 B2 JP 6031122B2 JP 2014548243 A JP2014548243 A JP 2014548243A JP 2014548243 A JP2014548243 A JP 2014548243A JP 6031122 B2 JP6031122 B2 JP 6031122B2
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JP2015502974A (ja
JP2015502974A5 (enExample
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フェドロビッチ ゴルデエフ ミハイル
フェドロビッチ ゴルデエフ ミハイル
リウ ジンキアン
リウ ジンキアン
ユアン ズヘンギュ
ユアン ズヘンギュ
ワング ジングハイ
ワング ジングハイ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
JP2014548243A 2011-12-22 2012-12-20 抗微生物療法のための三環式ホウ素化合物 Expired - Fee Related JP6031122B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161579271P 2011-12-22 2011-12-22
US61/579,271 2011-12-22
PCT/IB2012/002880 WO2013093615A1 (en) 2011-12-22 2012-12-20 Tricyclic boron compounds for antimicrobial therapy

Publications (3)

Publication Number Publication Date
JP2015502974A JP2015502974A (ja) 2015-01-29
JP2015502974A5 JP2015502974A5 (enExample) 2016-02-12
JP6031122B2 true JP6031122B2 (ja) 2016-11-24

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ID=47664367

Family Applications (1)

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JP2014548243A Expired - Fee Related JP6031122B2 (ja) 2011-12-22 2012-12-20 抗微生物療法のための三環式ホウ素化合物

Country Status (7)

Country Link
US (1) US8530452B2 (enExample)
EP (1) EP2793901A1 (enExample)
JP (1) JP6031122B2 (enExample)
KR (1) KR20140114380A (enExample)
CN (1) CN104136032B (enExample)
CA (1) CA2858799A1 (enExample)
WO (1) WO2013093615A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11039617B2 (en) 2013-01-30 2021-06-22 Agrofresh Inc. Large scale methods of uniformly coating packaging surfaces with a volatile antimicrobial to preserve food freshness
US10070649B2 (en) 2013-01-30 2018-09-11 Agrofresh Inc. Volatile applications against pathogens
AR094666A1 (es) * 2013-01-30 2015-08-19 Dow Agrosciences Llc Uso de benzoxaborolas como agentes antimicrobianos volátiles en carnes, plantas o partes de plantas
US9585396B2 (en) 2013-01-30 2017-03-07 Agrofresh Inc. Volatile applications against pathogens
KR101636431B1 (ko) * 2013-07-30 2016-07-05 동아에스티 주식회사 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
US20160251380A1 (en) * 2013-08-09 2016-09-01 Glaxosmithkline Intellectual Property (No.2) Limited Tricyclic benzoxaborole compounds and uses thereof
EA038093B1 (ru) * 2013-12-20 2021-07-05 Глаксосмитклайн Интеллекчуал Проперти (№2) Лимитед Способ лечения заболевания, вызванного инфекцией комплекса mycobacterium tuberculosis, с использованием (s)-(3-хлор-7,8-дигидро-2h-1,6,9-триокса-9a-борабензо[cd]азулен-2-ил)метанамина или его фармацевтически приемлемой соли
CN106459097A (zh) * 2014-07-01 2017-02-22 第三共株式会社 作为抗菌剂的三环苯并氧杂硼杂环戊烯类
CN104177226A (zh) * 2014-07-31 2014-12-03 河北国蓬化工有限公司 一种聚醚用催化剂的制备方法
MA41495A (fr) * 2015-02-12 2017-12-19 Anacor Pharmaceuticals Inc Composés benzoxaborole et leurs utilisations
WO2017155879A1 (en) 2016-03-07 2017-09-14 Agrofresh Inc. Synergistic methods of using benzoxaborole compounds and preservative gases as an antimicrobial for crops
KR101925338B1 (ko) 2016-12-22 2018-12-05 엘에스산전 주식회사 전력기기 진단 장치
EP3850029A1 (en) 2019-08-09 2021-07-21 Safas Saf Plastik Sanayi Ve Ticaret Anonim Sirketi Boron-modified flexible polyurethane foam for hygiene and a method of production therefor
CA3239097A1 (en) 2022-06-23 2023-12-28 Shanghai Micurx Pharmaceutical Co., Ltd. Prodrugs of boron compounds and their use in treating bacterial infections
JP2025520237A (ja) 2022-06-23 2025-07-03 ミクウルク ファーマシューティカルズ， インコーポレイテッド ホウ素化合物を用いて非結核性マイコバクテリア感染症を治療する方法及びその用途、並びに同じ疾患を治療するための医薬組成物
WO2025140370A1 (zh) * 2023-12-27 2025-07-03 上海盟科药业股份有限公司 硼化合物前药的盐型、晶型及其药物组合物和用途

Family Cites Families (16)

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US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US5023252A (en) 1985-12-04 1991-06-11 Conrex Pharmaceutical Corporation Transdermal and trans-membrane delivery of drugs
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5011472A (en) 1988-09-06 1991-04-30 Brown University Research Foundation Implantable delivery system for biological factors
CN1829521B (zh) 2003-06-16 2011-01-26 安纳考尔医药公司 耐水解的含硼治疗剂和使用方法
RU2642628C2 (ru) * 2006-02-16 2018-01-25 Анакор Фармасьютикалз, Инк. Бор-содержащие малые молекулы в качестве противовоспалительных средств
BRPI0711155A2 (pt) 2006-05-02 2011-08-23 Anacor Pharmaceuticals Inc terapêuticos contendo boro resistentes hidroliticamente e métodos de uso
US20070286822A1 (en) * 2006-06-12 2007-12-13 Anacor Pharmaceuticals Inc. Compounds for the Treatment of Periodontal Disease
JO3396B1 (ar) * 2007-06-20 2019-10-20 Anacor Pharmaceuticals Inc جزيئات صغيرة تحتوي على البورون
US20100256092A1 (en) * 2008-05-12 2010-10-07 Anacor Pharmaceuticals, Inc. Boron-containing small molecules
US20110259250A1 (en) 2008-08-21 2011-10-27 Mcknight James T Systems And Methods For Converting Biomass In The Field To A Combustible Fluid For Direct Replacement Or Supplement To Liquid Fossil Fuels
SG172040A1 (en) 2008-12-17 2011-07-28 Anacor Pharmaceuticals Inc Polymorphs of (s)-3-aminomethyl-7-(3-hydroxy-propoxy)-3h-benzo[c][1,2] oxaborol-1-ol
EP2458995A1 (en) 2009-07-28 2012-06-06 Anacor Pharmaceuticals, Inc. Trisubstituted boron-containing molecules
AU2011237681B2 (en) 2010-04-07 2015-01-22 Glaxosmithkline Llc Process for preparing benzoxaboroles
DK2613788T3 (en) 2010-09-07 2017-08-07 Anacor Pharmaceuticals Inc BENZOXABOROLD DERIVATIVES FOR TREATMENT OF BACTERIA INFECTIONS

Also Published As

Publication number Publication date
WO2013093615A1 (en) 2013-06-27
CN104136032A (zh) 2014-11-05
JP2015502974A (ja) 2015-01-29
EP2793901A1 (en) 2014-10-29
US20130165411A1 (en) 2013-06-27
KR20140114380A (ko) 2014-09-26
CA2858799A1 (en) 2013-06-27
CN104136032B (zh) 2018-11-13
US8530452B2 (en) 2013-09-10

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